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公开(公告)号:US09956315B2
公开(公告)日:2018-05-01
申请号:US11414682
申请日:2006-04-28
CPC分类号: A61L27/3604 , A61B17/0057 , A61B2017/00641 , A61K35/22 , A61K35/38 , A61L31/005
摘要: Described are medical products, systems, and methods for treating fistulae having a primary opening, such as in the alimentary canal. Certain methods of the invention include providing an implantable material including a compliant sheet form biocompatible material, and forcing this sheet form biocompatible material into the primary opening so as to deform the sheet form biocompatible material to conform to and block the primary opening. The biocompatible material preferably comprises a remodelable material, for example, a remodelable extracellular matrix material such as submucosa.
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2.
公开(公告)号:US09538996B2
公开(公告)日:2017-01-10
申请号:US11669695
申请日:2007-01-31
CPC分类号: A61B17/0057 , A61B1/31 , A61B17/12159 , A61B17/3468 , A61B50/30 , A61B2017/00004 , A61B2017/00628 , A61B2017/00641 , A61B2017/00654 , A61B2017/00659 , A61B2017/00862 , A61B2017/00867 , A61B2017/22038 , A61L27/24 , A61L27/3604 , A61L27/3633 , A61L27/3641 , A61L27/50
摘要: Described are medical graft products, systems, and methods for treating fistulae. Certain products of the invention are configured to have portions residing in and around a primary fistula opening, e.g., one occurring in a wall of the alimentary canal. One such product includes a biocompatible graft body which is configured to block at least the primary opening. The graft body includes a capping member, which is configured to contact portions of the alimentary canal wall adjacent to the primary opening, and an elongate plug member extending from the capping member, which is configured to extend into at least a portion of the fistula. In certain embodiments, a graft body component has the capacity to expand or otherwise change form to provide a suitable capping arrangement. Such a component can include a resilient wire frame, e.g., one that is self-expandable or one that requires at least some manipulation in order to expand.
摘要翻译: 描述了用于治疗瘘的医疗移植产品,系统和方法。 本发明的某些产品被配置为具有驻留在主瘘开口内和周围的部分,例如存在于消化道壁的一个。 一种这样的产品包括生物相容性移植物体,其构造成至少阻挡初级开口。 移植物主体包括封盖构件,其被构造成接触与初级开口相邻的消化道壁的部分,以及从封盖构件延伸的细长塞构件,其构造成延伸到至少一部分瘘。 在某些实施方案中,移植物体组分具有膨胀或以其它方式改变形式以提供合适的封盖装置的能力。 这样的部件可以包括弹性线框架,例如可自扩展的弹性线框架,或者需要至少一些操纵以便扩展的线框架。
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公开(公告)号:US09271817B2
公开(公告)日:2016-03-01
申请号:US12114456
申请日:2008-05-02
申请人: Ryan Dempsey , Jeffrey Miller , Steve Chen , Umesh H. Patel , F. Joseph Obermiller , Bhavin Shah , Chad E. Johnson
发明人: Ryan Dempsey , Jeffrey Miller , Steve Chen , Umesh H. Patel , F. Joseph Obermiller , Bhavin Shah , Chad E. Johnson
CPC分类号: A61F2/0059 , A61B17/06004 , A61B2017/06052 , A61F2/02 , A61L27/24 , A61M5/32 , A61M25/0662 , A61M2025/018 , Y10S623/915
摘要: Tissue augmentation devices, as well as methods of manufacturing and using the same, are disclosed. In certain embodiments, a tissue augmentation device comprises an elongate tissue penetrating member and an amount of remodelable material, wherein at least a portion of the elongate member is cannulated, and at least a portion of the amount of material is received within at least a portion of the cannulated portion of the elongate member. The elongate tissue penetrating member may provide at least one deformation that is configured to constrict portions of the amount of remodelable material received within the elongate member. In alternate embodiments, a flexible covering over an implantable biomaterial provides protection and allows an easier delivery of the biomaterial to a tissue tract.
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公开(公告)号:US07905826B2
公开(公告)日:2011-03-15
申请号:US11295866
申请日:2005-12-07
CPC分类号: A61L27/3633 , A61F2/2475 , A61L27/3604 , A61L27/3641 , A61L27/3645 , A61L27/3839
摘要: This invention relates in one aspect to the treatment of a vascular vessel with a biomaterial. The biomaterial can be a remodelable material that strengthens and/or supports the vessel walls. Additionally the biomaterial can include a variety of naturally occurring or added bioactive agents and/or viable cellular populations.
摘要翻译: 本发明在一个方面涉及用生物材料治疗血管血管。 生物材料可以是加强和/或支持血管壁的可重塑材料。 另外,生物材料可以包括多种天然存在或添加的生物活性剂和/或活细胞群体。
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公开(公告)号:US07897167B2
公开(公告)日:2011-03-01
申请号:US11472642
申请日:2006-06-21
IPC分类号: A61F2/02
CPC分类号: A61B17/0057 , A61B17/0401 , A61B17/06 , A61B17/06166 , A61B17/3468 , A61B50/30 , A61B2017/00004 , A61B2017/00628 , A61B2017/00641 , A61B2017/00646 , A61B2017/00654 , A61B2017/00659 , A61B2017/00898 , A61B2017/0404 , A61B2017/0464 , A61B2017/0496 , A61B2017/22038 , A61L27/227 , A61L27/24 , A61L27/3616 , A61L27/3629 , A61L27/3633 , A61L27/58 , A61M27/00
摘要: An implantable graft, which may be inserted into a fistula tract to occlude the primary opening of the fistula, is provided. To prevent unintentional displacement of the graft or extrusion of the graft from the fistula of a patient, the graft may be provided with a cap that extends laterally from at least one end of the body of the graft, where the cap may be integral with the body of the graft, attachable to at least one end of the body of the graft, and/or moveable along the body of the graft. The graft may also have a tail that extends from one end of the body of the graft to assist in placement of the graft in a fistula tract. The graft may be an integral unit made of a single material, such as a heterograft material, or may include distinct components made of the same or different materials. Methods for closing a fistula tract are also provided.
摘要翻译: 提供了一种植入式移植物,其可以插入瘘道以封闭瘘的主要开口。 为了防止移植物的意外移位或将移植物从患者的瘘管挤出,移植物可以设置有从移植物的主体的至少一端侧向延伸的帽,其中帽可以与 移植物的主体,可附接到移植物的身体的至少一端,和/或沿着移植物的主体移动。 移植物还可以具有从移植物的身体的一端延伸的尾部,以帮助将移植物放置在瘘管道中。 移植物可以是由诸如异种移植材料的单一材料制成的整体单元,或者可以包括由相同或不同材料制成的不同部件。 还提供了关闭瘘管的方法。
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公开(公告)号:US08834351B2
公开(公告)日:2014-09-16
申请号:US13048492
申请日:2011-03-15
CPC分类号: A61L27/3633 , A61F2/2475 , A61L27/3604 , A61L27/3641 , A61L27/3645 , A61L27/3839
摘要: This invention relates in one aspect to the treatment of a vascular vessel with a biomaterial. The biomaterial can be a remodelable material that strengthens and/or supports the vessel walls. Additionally the biomaterial can include a variety of naturally occurring or added bioactive agents and/or viable cellular populations.
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公开(公告)号:US08641776B2
公开(公告)日:2014-02-04
申请号:US13048458
申请日:2011-03-15
IPC分类号: A61F2/02
CPC分类号: A61B17/12 , A61F2/07 , A61F2/2475 , A61F2002/075 , A61F2002/077
摘要: This invention relates in one aspect to the treatment of a vascular vessel with a biomaterial. The biomaterial can be a remodelable material that strengthens and/or supports the vessel walls. Additionally the biomaterial can include a variety of naturally occurring or added bioactive agents and/or viable cellular populations.
摘要翻译: 本发明在一个方面涉及用生物材料治疗血管血管。 生物材料可以是加强和/或支持血管壁的可重塑材料。 另外,生物材料可以包括多种天然存在或添加的生物活性剂和/或活细胞群体。
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公开(公告)号:US20110125289A1
公开(公告)日:2011-05-26
申请号:US13018582
申请日:2011-02-01
IPC分类号: A61F2/02
CPC分类号: A61B17/0057 , A61B17/0401 , A61B17/06 , A61B17/06166 , A61B17/3468 , A61B50/30 , A61B2017/00004 , A61B2017/00628 , A61B2017/00641 , A61B2017/00646 , A61B2017/00654 , A61B2017/00659 , A61B2017/00898 , A61B2017/0404 , A61B2017/0464 , A61B2017/0496 , A61B2017/22038 , A61L27/227 , A61L27/24 , A61L27/3616 , A61L27/3629 , A61L27/3633 , A61L27/58 , A61M27/00
摘要: An implantable graft, which may be inserted into a fistula tract to occlude the primary opening of the fistula, is provided. To prevent unintentional displacement of the graft or extrusion of the graft from the fistula of a patient, the graft may be provided with a cap that extends laterally from at least one end of the body of the graft, where the cap may be integral with the body of the graft, attachable to at least one end of the body of the graft, and/or moveable along the body of the graft. The graft may also have a tail that extends from one end of the body of the graft to assist in placement of the graft in a fistula tract. The graft may be an integral unit made of a single material, such as a heterograft material, or may include distinct components made of the same or different materials. Methods for closing a fistula tract are also provided.
摘要翻译: 提供了一种植入式移植物,其可以插入瘘道以封闭瘘的主要开口。 为了防止移植物的意外移位或将移植物从患者的瘘管挤出,移植物可以设置有从移植物的主体的至少一端侧向延伸的帽,其中帽可以与 移植物的主体,可附接到移植物的身体的至少一端,和/或沿着移植物的主体移动。 移植物还可以具有从移植物的身体的一端延伸的尾部,以帮助将移植物放置在瘘管道中。 移植物可以是由诸如异种移植材料的单一材料制成的整体单元,或者可以包括由相同或不同材料制成的不同部件。 还提供了关闭瘘管的方法。
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9.
公开(公告)号:US20110060362A1
公开(公告)日:2011-03-10
申请号:US12948177
申请日:2010-11-17
IPC分类号: A61B17/03
CPC分类号: A61B17/0057 , A61B2017/00004 , A61B2017/00641
摘要: Provided by certain aspects of the invention are methods for treating fistulae and various fistula graft assemblages useful in this regard. Illustratively, some inventive methods are useful in treating fistulae having at least a first fistula opening, a second fistula opening and a fistula tract extending therebetween. In one step, a first capping member is positioned over the first fistula opening such that a first pulling member, which extends from the first capping member, passes through the fistula tract. In another step, a second capping member is positioned over the second fistula opening such that a second pulling member, which extends from the second capping member, passes through the fistula tract. A first pulling force is applied to the first pulling member, and a second pulling force is applied to the second pulling member, for maintaining the first capping member over the first fistula opening and for maintaining the second capping member over the second fistula opening, respectively.
摘要翻译: 由本发明的某些方面提供的是用于治疗瘘管和各种瘘移植物组合物的方法。 说明性地,一些本发明的方法可用于治疗具有至少第一瘘开口,第二瘘开口和在其间延伸的瘘管道的瘘。 在一个步骤中,第一封盖构件定位在第一瘘开口上方,使得从第一封盖构件延伸的第一牵引构件穿过瘘管道。 在另一步骤中,第二封盖构件定位在第二瘘开口上方,使得从第二封盖构件延伸的第二牵引构件穿过瘘管道。 第一拉力被施加到第一牵引构件,并且第二拉力施加到第二牵引构件,用于将第一封盖构件保持在第一瘘开口上方并且用于将第二封盖构件分别保持在第二瘘开口上方 。
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公开(公告)号:US20110046576A1
公开(公告)日:2011-02-24
申请号:US12939636
申请日:2010-11-04
IPC分类号: A61M5/00
CPC分类号: A61F2/0059
摘要: Tissue augmentation devices, as well as methods of manufacturing and using the same, are disclosed. In certain embodiments, a tissue augmentation device comprises an elongate tissue penetrating member and an amount of remodelable material, wherein at least a portion of the elongate member is cannulated, and at least a portion of the amount of material is received within at least a portion of the cannulated portion of the elongate member. The elongate tissue penetrating member may provide at least one deformation that is configured to constrict portions of the amount of remodelable material received within the elongate member. In alternate embodiments, a flexible covering over an implantable biomaterial provides protection and allows an easier delivery of the biomaterial to a tissue tract.
摘要翻译: 公开了组织增加装置,以及制造和使用它们的方法。 在某些实施例中,组织增强装置包括细长的组织穿透构件和一定量的可重塑材料,其中细长构件的至少一部分被插管,并且至少部分材料量被容纳在至少一部分内 的细长构件的插管部分。 细长组织穿透构件可以提供至少一个变形,其被构造成收缩在细长构件内容纳的可重塑材料的量的部分。 在替代实施例中,可植入生物材料上的柔性覆盖物提供保护并且允许将生物材料更容易地递送到组织道。
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