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公开(公告)号：US20130134079A1
公开(公告)日：2013-05-30
申请号：US13677695
申请日：2012-11-15
Applicant: WATERS TECHNOLOGIES CORPORATION
Inventor： Joseph A. Jarrell , Pamela C. Iraneta , Douglas P. Wittmer
IPC: B01D15/14
CPC classification number: B01D15/14 , G01N30/30 , G01N30/32 , G01N30/34 , G01N2030/8881 , G01N2030/342 , B01D15/40
Abstract: Described is a mobile phase solvent delivery module for liquid chromatography and supercritical fluid chromatography systems. The module includes a pump disposed in a fluid path that conducts a mobile phase solvent. The pump provides the mobile phase solvent at an increased pressure. The module also includes a purification cartridge disposed in the fluid path either before or after the pump. The purification cartridge has an inlet to receive the mobile phase solvent and an outlet to provide a purified mobile phase solvent, and includes a packing material for removing an impurity from the mobile phase solvent. In various embodiments, the module also includes one or more additional components to allow various techniques for regeneration or replacement of spent purification cartridges. For example, the module may also include one or more of a temperature control module, a fluidic switch and one or more additional purification cartridges.
Abstract translation: 描述了用于液相色谱和超临界流体色谱系统的流动相溶剂递送模块。 模块包括设置在流动路径中的泵，其传导流动相溶剂。 该泵在增加的压力下提供流动相溶剂。 该模块还包括在泵之前或之后设置在流体路径中的净化筒。 净化筒具有容纳流动相溶剂的入口和出口以提供纯化的流动相溶剂，并且包括用于从流动相溶剂中除去杂质的填充材料。 在各种实施例中，模块还包括一个或多个附加部件，以允许用于再生或更换废净化筒的各种技术。 例如，模块还可以包括温度控制模块，流体开关和一个或多个附加的净化盒中的一个或多个。
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公开(公告)号：US20150047422A1
公开(公告)日：2015-02-19
申请号：US14383239
申请日：2013-03-05
Applicant: Waters Technologies Corporation
Inventor： Emily J. Berg , Joshua A. Shreve , James E. Usowicz , Douglas P. Wittmer , Aaron Lebeau
CPC classification number: B01D15/14 , B01D15/40 , G01N30/16 , G01N30/20 , G01N30/28 , G01N2030/201 , G01N2030/202 , G01N2030/207 , G01N30/32
Abstract: A supercritical fluid chromatography system is provided with an injection valve subsystem for introducing a sample into a flow of mobile phase fluid. The injection valve subsystem includes an auxiliary valve and an inject valve. The operations of the auxiliary and inject valves are coordinated in such a manner as to reduce sample carry-over and system pressure perturbations occurring during sample injection.
Abstract translation: 超临界流体色谱系统设置有用于将样品引入流动相流体流的注射阀子系统。 喷射阀子系统包括辅助阀和喷射阀。 辅助和注入阀的操作以减少样品注入期间发生的样品携带和系统压力扰动的方式进行协调。
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公开(公告)号：US10183238B2
公开(公告)日：2019-01-22
申请号：US14383241
申请日：2013-03-05
Applicant: Waters Technologies Corporation
Inventor： Michael R. Jackson , James E. Usowicz , Lucas O. Tiziani , Joseph A. Jarrell , Douglas P. Wittmer
IPC: B01D15/08 , B01D15/14 , B01D15/40 , F04B15/08 , G01N1/40 , G01N30/10 , G01N30/38 , G01N30/72 , G01N30/74 , G01N30/88 , H01J49/04 , G01N30/02 , F04B53/10 , G01N30/24
Abstract: A method includes passing a mobile phase fluid flow comprising liquefied CO2 through a separation column; then introducing a makeup fluid flow into the mobile phase fluid flow to form a mixed fluid flow; and then splitting the mixed fluid flow.
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公开(公告)号：US09764251B2
公开(公告)日：2017-09-19
申请号：US14383239
申请日：2013-03-05
Applicant: Waters Technologies Corporation
Inventor： Emily J. Berg , Joshua A. Shreve , James E. Usowicz , Douglas P. Wittmer , Aaron Lebeau
CPC classification number: B01D15/14 , B01D15/40 , G01N30/16 , G01N30/20 , G01N30/28 , G01N2030/201 , G01N2030/202 , G01N2030/207 , G01N30/32
Abstract: A supercritical fluid chromatography system is provided with an injection valve subsystem for introducing a sample into a flow of mobile phase fluid. The injection valve subsystem includes an auxiliary valve and an inject valve. The operations of the auxiliary and inject valves are coordinated in such a manner as to reduce sample carry-over and system pressure perturbations occurring during sample injection.
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