公开(公告)号：US20180327431A1

公开(公告)日：2018-11-15

申请号：US15771017

申请日：2016-10-18

申请人： Nelson Mandela Metropolitan University

发明人： Fidelis CHIGONDO ,  Paul WATTS

IPC分类号： C07F7/02 ,  B01J23/72 ,  B01J21/06 ,  B01J35/00 ,  B01J37/04

CPC分类号： C07F7/025 ,  B01J21/06 ,  B01J23/72 ,  B01J27/122 ,  B01J35/0006 ,  B01J37/04

摘要： The invention provides a direct solvent free method for the selective synthesis of trialkoxysilanes having the formula SiH(OR)3, the method comprises providing a mixture of metallic silicon and copper based catalyst in a packed bed reactor, wherein neither the metallic silicon nor the silicon-catalyst mixture is subjected to any washing step. Claim 1 relates to a direct solvent free method for the selective synthesis of trialkoxysilanes having the formula SiH(OR)3, wherein each R is a C1-C4 alkyl, the method comprising the steps of: providing a mixture of metallic silicon and copper based catalyst in a packed bed reactor; heating the mixture at an activation temperature of about 180° C.-about 250° C.; introducing C1-C4 alcohol to the reactor at a reaction temperature of about 180° C.-less than about 250° C.; condensing the reaction products in a heat exchanger; and collecting the condensed reaction products, wherein neither the metallic silicon nor the silicon-catalyst mixture is subjected to any washing step, including a hydro fluoric acid (HF) washing step.

公开(公告)号：US10815223B2

公开(公告)日：2020-10-27

申请号：US16301255

申请日：2017-06-13

申请人： Nelson Mandela Metropolitan University

发明人： Devender Mandala ,  Paul Watts

IPC分类号： C07D411/04

摘要： This invention provides for flow and batch synthesis processes for the production of Lamivudine and Emtricitabine, including flow and batch synthesis processes wherein at least of the synthesis steps are conducted in a solvent free environment.

公开(公告)号：US10538715B2

公开(公告)日：2020-01-21

申请号：US14892873

申请日：2014-05-08

申请人： Nelson Mandela Metropolitan University

发明人： Bernard Zeelie

IPC分类号： C10L5/04 ,  B09B3/00 ,  C10L5/36 ,  C10L9/10

摘要： A method for upgrading coal fines by separating out at least some mineral components is provided. The method comprises the treatment of optionally graded coal fines with microalgae in aqueous medium to form a slurry under conditions that permit adsorption of microalgae onto particles of coal fines. The slurry is treated to separate a first fraction that is rich in coal fines together with adsorbed microalgae thereon from a second fraction that has more mineral components in it than does the first fraction and processing the first fraction to recover upgraded coal fines therefrom. Contacting is preferably carried out in a manner aimed at loading the coal fines generally evenly with microalgae adsorbed thereon in an amount of from 5 to 15% by weight of coal fines. Separation may be carried out by sedimentation, cyclone separation or flotation.

公开(公告)号：US20140247068A1

公开(公告)日：2014-09-04

申请号：US14353215

申请日：2012-10-19

申请人： Nelson Mandela Metropolitan University

发明人： Farouk Smith

IPC分类号： H03K19/003 ,  H03K19/00 ,  H03K19/007

CPC分类号： H03K19/00346 ,  G01R31/31816 ,  H03K19/0008 ,  H03K19/0033 ,  H03K19/0075

摘要： A circuit structure (200) for suppressing single event transients (SETs) or glitches in digital electronic circuits is provided. The circuit structure includes a first input (100) which receives an output of a digital electronic circuit (A), a second input (100′) which receives a redundant or duplicated output of the digital electronic circuit (A′), and two sub-circuits (102, 106) that each receive the inputs and have one output. One of the sub-circuits is insensitive to a change in the value of one of its inputs when the inputs are in a first logic state and the other sub-circuit is insensitive to a change in the value of one of the inputs when the inputs are in a second, inverted logic state. The sub-circuit outputs are input into a two-input multiplexer (202) which has its output (204) connected to its selection port (SEL), and the sub-circuits are arranged so that the sub-circuit which is insensitive to a change in the value of one of its inputs is selected whenever the output of the multiplexer changes. The multiplexer output (204) is provided as a final output in which SETs and glitches have been suppressed.

摘要翻译： 提供了用于抑制数字电子电路中的单事件瞬变（SET）或毛刺的电路结构（200）。 电路结构包括接收数字电子电路（A）的输出的第一输入（100），接收数字电子电路（A'）的冗余或复制输出的第二输入（100'）和两个子 - 电路（102,106），每个接收输入并具有一个输出。 当输入处于第一逻辑状态时，其中一个子电路对其输入之一的值的变化不敏感，另一个子电路对输入之一的值的变化不敏感时 处于第二个反转逻辑状态。 子电路输出被输入到其输出（204）连接到其选择端口（SEL）的双输入多路复用器（202）中，并且子电路被布置成使得不对A的电路不敏感的子电路 每当多路复用器的输出变化时，选择其输入之一的值的变化。 复用器输出（204）被提供为其中已经抑制了集合和毛刺的最终输出。

公开(公告)号：US10570160B2

公开(公告)日：2020-02-25

申请号：US15771017

申请日：2016-10-18

申请人： Nelson Mandela Metropolitan University

发明人： Fidelis Chigondo ,  Paul Watts

IPC分类号： B01J23/72 ,  C07F7/02 ,  B01J37/04 ,  B01J35/00 ,  B01J21/06

摘要： The invention provides a direct solvent free method for the selective synthesis of trialkoxysilanes having the formula SiH(OR)3, the method comprises providing a mixture of metallic silicon and copper based catalyst in a packed bed reactor, wherein neither the metallic silicon nor the silicon-catalyst mixture is subjected to any washing step. Claim 1 relates to a direct solvent free method for the selective synthesis of trialkoxysilanes having the formula SiH(OR)3, wherein each R is a C1-C4 alkyl, the method comprising the steps of: providing a mixture of metallic silicon and copper based catalyst in a packed bed reactor; heating the mixture at an activation temperature of about 180° C.-about 250° C.; introducing C1-C4 alcohol to the reactor at a reaction temperature of about 180° C.-less than about 250° C.; condensing the reaction products in a heat exchanger; and collecting the condensed reaction products, wherein neither the metallic silicon nor the silicon-catalyst mixture is subjected to any washing step, including a hydro fluoric acid (HF) washing step.

公开(公告)号：US20110198389A1

公开(公告)日：2011-08-18

申请号：US12995014

申请日：2009-05-29

申请人： Daniel Gerhardus Hattingh ,  Ian Norman Wedderburn ,  Philip Doubell

发明人： Daniel Gerhardus Hattingh ,  Ian Norman Wedderburn ,  Philip Doubell

IPC分类号： B23K20/12 ,  B23K31/02

CPC分类号： B23K20/1215 ,  B23K20/1245 ,  B23K20/127 ,  B23K20/129 ,  B23K20/1295 ,  B23K2101/10 ,  G01N1/08

摘要： This invention relates to a friction welding apparatus, and more particularly, but not exclusively, to a modular friction welding apparatus suitable for in-situ reparation of blind holes in pipes. The friction welding apparatus includes a frame assembly, a spindle assembly for holding a friction welding consumable; and a drive assembly for driving a spindle of the spindle assembly. The spindle assembly and the drive assembly are releasably securable to the frame assembly so as to form a modular friction welding apparatus, and the frame assembly is furthermore removable securable to an object to be welded.

摘要翻译： 本发明涉及一种摩擦焊接装置，更具体地但非排他地涉及一种适于在管道中盲孔进行原位修复的模块式摩擦焊接装置。 摩擦焊接装置包括框架组件，用于保持摩擦焊接消耗品的主轴组件; 以及用于驱动主轴组件的主轴的驱动组件。 主轴组件和驱动组件可释放地固定到框架组件上，以便形成模块式摩擦焊接装置，并且框架组件进一步可拆卸地安装到被焊接物体上。

公开(公告)号：US20200062722A1

公开(公告)日：2020-02-27

申请号：US16488975

申请日：2018-02-15

申请人： NELSON MANDELA METROPOLITAN UNIVERSITY

发明人： Paul Watts ,  Sravanthi Chada

IPC分类号： C07D263/58

摘要： This invention relates to a method for the manufacture of optically pure (S)-6-chloro-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one. Specifically, this invention relates to a flow synthesis method for the manufacture of (S)-6-chloro-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one.

公开(公告)号：US10442621B2

公开(公告)日：2019-10-15

申请号：US15520589

申请日：2015-10-19

申请人： Nelson Mandela Metropolitan University

发明人： Adriane Michele Bestic ,  Ashley Mark Naude ,  Shuldham Shaun Peard ,  Christopher John Sephton

IPC分类号： B65G1/04 ,  B65D25/22 ,  B65D81/20 ,  B65G1/06 ,  G05D1/02 ,  B65D51/16

摘要： A racking system and components are provided in which multiple storage positions are provided for individual storage boxes and automated guided vehicles are present to carry out automated placement, relocation and retrieval of boxes from storage positions in which they are located. The racking system has horizontally extending storage layers in each of which multiple storage positions are located and alternating vertically juxtaposed transfer layers in which automated guided vehicles are movable in at least two directions that are at right angles to each other to place, relocate and retrieve boxes to and from storage positions by vertical movement of the boxes into and out of storage positions in storage layers located above or below a transfer layer. The storage positions have associated with them storage guides for guiding boxes into and out of the storage positions and support arrangements for supporting the boxes in their storage positions.

公开(公告)号：US20160115410A1

公开(公告)日：2016-04-28

申请号：US14892873

申请日：2014-05-08

申请人： NELSON MANDELA METROPOLITAN UNIVERSITY

发明人： Bernard Zeelie

IPC分类号： C10L5/04 ,  C10L5/36 ,  C10L9/10 ,  B09B3/00

摘要： A method for upgrading coal fines by separating out at least some mineral components is provided. The method comprises the treatment of optionally graded coal fines with micro-algae in aqueous medium to form a slurry under conditions that permit adsorption of micro-algae onto particles of coal fines. The slurry is treated to separate a first fraction that is rich in coal fines together with adsorbed micro-algae thereon from a second fraction that has more mineral components in it than does the first fraction and processing the first fraction to recover upgraded coal fines therefrom. Contacting is preferably carried out in a manner aimed at loading the coal fines generally evenly with microalgae adsorbed thereon in an amount of from 5 to 15% by weight of coal fines. Separation may be carried out by sedimentation, cyclone separation or flotation.

摘要翻译： 提供了通过分离至少一些矿物成分来提炼煤粉的方法。 该方法包括在水介质中用微藻处理任选分级的煤粉，以在允许微藻吸附在细粉颗粒上的条件下形成浆料。 将浆料处理以将富含细粉的第一级分与其上吸附的微藻类分离，其中比第一级分具有更多矿物组分的第二级分，并处理第一馏分以从其中回收升级的煤粉。 接触优选的方式是以通常以5-15％重量的煤粉的量吸附在其上的微藻大致均匀地装载煤粉的方式进行。 分离可以通过沉降，旋风分离或浮选进行。

公开(公告)号：US20100305332A1

公开(公告)日：2010-12-02

申请号：US12302010

申请日：2007-05-22

申请人： Christopher Dennis Woolard ,  Damien Christopher Williams ,  Jason Leigh van Rooyen ,  Katherine Garde ,  Robert Michael Bosch ,  Stefanus Hendrik Josephus Strydom

发明人： Christopher Dennis Woolard ,  Damien Christopher Williams ,  Jason Leigh van Rooyen ,  Katherine Garde ,  Robert Michael Bosch ,  Stefanus Hendrik Josephus Strydom

IPC分类号： C07F3/08 ,  C07F3/06

CPC分类号： C01G1/02 ,  B82Y30/00 ,  C01G1/12 ,  C01G9/02 ,  C01G9/06 ,  C01G11/02 ,  C01P2002/72 ,  C01P2002/88 ,  C01P2004/64 ,  C08K3/22 ,  C08K3/30 ,  C08K9/04 ,  C08L21/00

摘要： The present invention relates to a method for the preparation of a functionalized nano size transition metal oxide or sulfide particle comprising the steps of (a) providing a ternary solvent system comprising a polar solvent, a non-polar solvent and an intermediate solvent allowing miscibility of all three components; (b) providing a mixture of a transition metal salt and a ternary solvent; (c) providing a mixture of a suitable source of oxide or sulfide and the ternary solvent; (d) providing a mixture of a non-polar end capping agent and the non-polar solvent; (e) mixing the mixtures; and (f) recovering the resultant functionalized nano size transition metal oxide or sulfide particle. The invention further relates to non-polar end capped nano sized transition metal oxide or sulfide particle so produced and the use of such particles.

摘要翻译： 本发明涉及一种制备官能化纳米尺寸过渡金属氧化物或硫化物颗粒的方法，包括以下步骤：（a）提供包含极性溶剂，非极性溶剂和中间体溶剂的三元溶剂体系，其允许 所有三个组成部分; （b）提供过渡金属盐和三元溶剂的混合物; （c）提供合适的氧化物或硫化物源和三元溶剂的混合物; （d）提供非极性封端剂和非极性溶剂的混合物; （e）混合混合物; 和（f）回收得到的官能化纳米尺寸的过渡金属氧化物或硫化物颗粒。 本发明还涉及如此制备的非极性封端的纳米尺寸的过渡金属氧化物或硫化物颗粒以及这种颗粒的使用。