公开(公告)号：US20240351970A1

公开(公告)日：2024-10-24

申请号：US18683577

申请日：2021-12-24

Applicant: ZHEJIANG AUSUN PHARMACEUTICAL CO., LTD.

Inventor： Yunfeng LI ,  Zhiguo ZHENG

IPC: C07C51/377 ,  B01J23/72 ,  B01J27/122 ,  C07C41/01 ,  C07C227/16 ,  C07D309/10

CPC classification number: C07C51/377 ,  B01J23/72 ,  B01J27/122 ,  C07C41/01 ,  C07C227/16 ,  C07D309/10

Abstract: The invention relates to a preparation method and application of 5-bromo-2-chloro-benzoic acid as a synthetic raw material of a hypoglycemic agent. Specifically, the 5-bromo-2-chloro-benzoic acid is prepared by taking a 5-bromo-2-aminobenzoic acid derivative as an initial raw material through two steps of reactions of diazotization, chlorination and hydrolysis, and the obtained product has the advantages of few isomer impurities, high reaction yield, good purity, low cost and suitability for industrial production. The invention also relates to the application of the 5-bromo-2-amino-benzoic acid in preparing antidiabetic drugs.

公开(公告)号：US20240208966A1

公开(公告)日：2024-06-27

申请号：US18286964

申请日：2022-04-07

Applicant: SIEGFRIED AG

Inventor： Beat Theodor Weber ,  Fuping Huang ,  Mounuo Cheng ,  Chunli Cao

IPC: C07D471/04 ,  B01J27/055 ,  B01J27/122 ,  B01J31/02

CPC classification number: C07D471/04 ,  B01J27/055 ,  B01J27/122 ,  B01J31/0238 ,  B01J2231/64 ,  B01J2531/007

Abstract: The present invention relates to a novel method of producing a compound of Formula (I) from a compound of formula (II) by a novel cyclisation process, as well as a method of producing an acid adduct of the compound of Formula (I) wherein L represents a leaving group, and R represents hydrogen, a substituted or unsubstituted linear, branched and/or cyclic alkyl group that may contain one or more hetero atoms in the linear, branched and/or cyclic alkyl chain, a substituted or unsubstituted aromatic or heteroaromatic group, a substituted or unsubstituted linear, branched and/or cyclic aralkyl or heteroaromatic alkyl group that may contain one or more hetero atoms in the linear, branched and/or cyclic alkanediyl chain, or a substituted or unsubstituted alkylaryl or alkyl heteroaromatic group with at least one linear, branched and/or cyclic alkyl residue that may contain one or more hetero atoms in the linear, branched and/or cyclic alkyl chain.

公开(公告)号：US11986806B2

公开(公告)日：2024-05-21

申请号：US17115846

申请日：2020-12-09

Applicant: FUJITSU LIMITED

Inventor： Michio Ushigome ,  Masato Wakamura ,  Osamu Tsuboi

IPC: B01J27/122 ,  B01J35/00 ,  C01G3/04 ,  G01N27/12 ,  B01J37/02

CPC classification number: B01J27/122 ,  B01J35/004 ,  C01G3/04 ,  G01N27/125

Abstract: A photocatalyst made of cuprous bromide, wherein the cuprous bromide expresses a photocatalytic property of decomposing a substance brought into contact with the cuprous bromide by irradiation with light.

公开(公告)号：US11951459B2

公开(公告)日：2024-04-09

申请号：US17115846

申请日：2020-12-09

Applicant: FUJITSU LIMITED

Inventor： Michio Ushigome ,  Masato Wakamura ,  Osamu Tsuboi

IPC: B01J27/122 ,  B01J35/00 ,  C01G3/04 ,  G01N27/12 ,  B01J37/02

CPC classification number: B01J27/122 ,  B01J35/004 ,  C01G3/04 ,  G01N27/125

Abstract: A photocatalyst made of cuprous bromide, wherein the cuprous bromide expresses a photocatalytic property of decomposing a substance brought into contact with the cuprous bromide by irradiation with light.

公开(公告)号：US11643379B2

公开(公告)日：2023-05-09

申请号：US17209699

申请日：2021-03-23

Applicant: Corning Incorporated ,  Liaoning Shihua University

Inventor： Mingqian He ,  Yang Li ,  Jing Sun ,  Hongxiang Wang ,  Mong-dong Zhou

IPC: C07C29/10 ,  B01J27/122 ,  C07C41/30 ,  B01J31/22 ,  C07C41/01 ,  C07C43/164 ,  C07C29/00 ,  C07C51/305

CPC classification number: C07C29/10 ,  B01J27/122 ,  B01J31/226 ,  C07C29/00 ,  C07C41/01 ,  C07C41/30 ,  C07C43/164 ,  B01J2231/4205 ,  B01J2531/16 ,  C07C51/305

Abstract: A method includes: providing a mixture including at least one alkyl tosylate and a Grignard reagent; and reacting the at least one alkyl tosylate with the Grignard reagent in a C—C coupling reaction mechanism to form a branched aliphatic alcohol.

公开(公告)号：US20180029026A1

公开(公告)日：2018-02-01

申请号：US15661016

申请日：2017-07-27

Applicant: The Procter & Gamble Company ,  Friedrich Alexander Universitat Erlangen-Nurnberg

Inventor： Jakob Albert ,  Peter Wasserscheid ,  Nicola Taccardi ,  Jens Nagengast ,  Matthias Kehrer ,  Julian Kadar ,  Dimitris Ioannis Collias

IPC: B01J31/02 ,  B01J31/04 ,  B01J27/02 ,  B01J27/16 ,  B01J27/06

CPC classification number: B01J31/0288 ,  B01J27/02 ,  B01J27/06 ,  B01J27/122 ,  B01J27/125 ,  B01J27/138 ,  B01J27/16 ,  B01J31/0298 ,  B01J31/04 ,  B01J31/26

Abstract: Catalysts for the dehydration of lactic acid, lactic acid derivatives, or mixtures thereof to acrylic acid, acrylic acid derivatives, or mixtures thereof in liquid phase comprising an ionic liquid (IL) and an acid are provided.

公开(公告)号：US20160040304A1

公开(公告)日：2016-02-11

申请号：US14877329

申请日：2015-10-07

Applicant: CALERA CORPORATION

Inventor： Thomas A. Albrecht ,  Ryan J. Gilliam ,  Kyle Self ,  Dennis W. Solas ,  Margarete K. Leclerc

IPC: C25B1/26 ,  C25B11/04 ,  C25B1/02 ,  C25B1/18

CPC classification number: C25B3/06 ,  B01J27/122 ,  B01J27/132 ,  C07C17/02 ,  C07D301/03 ,  C25B1/00 ,  C25B1/02 ,  C25B1/16 ,  C25B1/18 ,  C25B1/20 ,  C25B1/26 ,  C25B1/46 ,  C25B3/02 ,  C25B9/06 ,  C25B9/08 ,  C25B11/0489 ,  Y02E60/366

Abstract: There are provided methods and systems for an electrochemical cell including an anode and a cathode where the anode is contacted with a metal ion that converts the metal ion from a lower oxidation state to a higher oxidation state. The metal ion in the higher oxidation state is reacted with hydrogen gas, an unsaturated hydrocarbon, and/or a saturated hydrocarbon to form products.

公开(公告)号：US09187834B2

公开(公告)日：2015-11-17

申请号：US13474598

申请日：2012-05-17

Applicant: Thomas A. Albrecht ,  Ryan J. Gilliam ,  Bryan Boggs ,  Kyle Self ,  Dennis W. Solas ,  Michael Kostowskyj ,  Margarete K. Leclerc ,  Alexander Gorer ,  Michael Joseph Weiss

Inventor： Thomas A. Albrecht ,  Ryan J. Gilliam ,  Bryan Boggs ,  Kyle Self ,  Dennis W. Solas ,  Michael Kostowskyj ,  Margarete K. Leclerc ,  Alexander Gorer ,  Michael Joseph Weiss

IPC: C07C17/00 ,  C07C315/00 ,  C08F14/06 ,  C25B1/20 ,  C25B1/00 ,  C25B1/02

CPC classification number: C25B3/06 ,  B01J27/122 ,  B01J27/132 ,  C07C17/02 ,  C07D301/03 ,  C25B1/00 ,  C25B1/02 ,  C25B1/16 ,  C25B1/18 ,  C25B1/20 ,  C25B1/26 ,  C25B1/46 ,  C25B3/02 ,  C25B9/06 ,  C25B9/08 ,  C25B11/0489 ,  Y02E60/366

Abstract: There are provided methods and systems for an electrochemical cell including an anode and a cathode where the anode is contacted with a metal ion that converts the metal ion from a lower oxidation state to a higher oxidation state. The metal ion in the higher oxidation state is reacted with hydrogen gas, an unsaturated hydrocarbon, and/or a saturated hydrocarbon to form products.

Abstract translation: 提供了包括阳极和阴极的电化学电池的方法和系统，其中阳极与将金属离子从较低氧化态转化为较高氧化态的金属离子接触。 较高氧化态的金属离子与氢气，不饱和烃和/或饱和烃反应形成产物。

公开(公告)号：US09079875B2

公开(公告)日：2015-07-14

申请号：US11913626

申请日：2006-05-10

Applicant: Lukas Goossen ,  Guojun Deng

Inventor： Lukas Goossen ,  Guojun Deng

IPC: C07C63/00 ,  C07C65/00 ,  C07C61/00 ,  C07C61/08 ,  C07C19/00 ,  C07C2/66 ,  C07C5/09 ,  C07C15/40 ,  C07C2/26 ,  C07D333/08 ,  B01J31/18 ,  B01J31/22 ,  B01J31/24 ,  B01J31/26 ,  C07B37/04 ,  C07C1/26 ,  C07C17/263 ,  C07C17/266 ,  C07C41/30 ,  C07C45/68 ,  C07C45/72 ,  C07C201/12 ,  C07C209/68 ,  C07C231/12 ,  C07C253/30 ,  C07C315/04 ,  C07C319/20 ,  B01J27/122 ,  B01J27/232

CPC classification number: C07D333/08 ,  B01J27/122 ,  B01J27/232 ,  B01J31/1815 ,  B01J31/183 ,  B01J31/2234 ,  B01J31/2404 ,  B01J31/26 ,  B01J2231/4205 ,  B01J2531/0241 ,  B01J2531/16 ,  B01J2531/17 ,  B01J2531/824 ,  C07B37/04 ,  C07C1/26 ,  C07C17/263 ,  C07C17/2637 ,  C07C17/266 ,  C07C41/30 ,  C07C45/68 ,  C07C45/72 ,  C07C201/12 ,  C07C209/68 ,  C07C231/12 ,  C07C253/30 ,  C07C315/04 ,  C07C319/20 ,  C07C2527/122 ,  C07C2531/24 ,  C07C2531/28 ,  C07C2531/30 ,  C07C2603/26 ,  C07C15/52 ,  C07C25/18 ,  C07C25/24 ,  C07C49/782 ,  C07C47/546 ,  C07C49/84 ,  C07C317/14 ,  C07C211/55 ,  C07C233/07 ,  C07C255/64 ,  C07C323/09 ,  C07C205/06 ,  C07C205/11 ,  C07C205/35 ,  C07C205/44 ,  C07C205/45 ,  C07C205/57 ,  C07C43/205

Abstract: The invention relates to a method for decarboxylating C—C bond formation by reacting carboxylic salts with carbon electrophiles in the presence of transition metal compounds as catalysts. The method represents a decarboxylating C—C bond formation of carboxylic acid salts with carbon electrophiles, wherein the catalyst contains two transition metals and/or transition metal compounds, from which one is present, preferably, in the oxidation step, which are different from each other by one unit, and catalyzes a radical decarboxylation which is absorbed during the second oxidation steps, which are different from each other by two units and catalyzes the two electron processes of a C—C bond formation reaction.

Abstract translation: 本发明涉及通过在过渡金属化合物作为催化剂存在下使羧酸与碳亲电体反应来脱羧C-C键形成的方法。 该方法表示与碳亲电体形成羧酸盐的羧基C-C键，其中催化剂含有两种过渡金属和/或过渡金属化合物，优选在氧化步骤中存在一种不同于 催化自由基脱羧，其在第二氧化步骤期间被吸收，它们通过两个单元彼此不同并且催化C-C键形成反应的两个电子过程。

公开(公告)号：US20140294989A1

公开(公告)日：2014-10-02

申请号：US14002276

申请日：2012-12-17

Applicant: SHOWA DENKO K.K.

Inventor： So Miyaishi ,  Yasushi Kuroka ,  Yasuhiro Hosogi ,  Ding Li

IPC: A01N59/20 ,  B01J27/135 ,  A61L9/01 ,  B01J27/055 ,  B01J27/25 ,  A01N55/02 ,  B01J23/72 ,  B01J31/38

CPC classification number: A01N59/16 ,  A01N55/02 ,  A01N59/20 ,  A61L9/01 ,  B01J21/063 ,  B01J23/72 ,  B01J27/055 ,  B01J27/122 ,  B01J27/135 ,  B01J27/25 ,  B01J31/38 ,  B01J35/004 ,  B01J37/033 ,  A01N25/08 ,  A01N2300/00

Abstract: The Cu- and Ti-containing composition of the present invention contains titanium oxide including rutile-crystal-type titanium oxide, and a divalent copper compound, wherein the rutile-crystal-type titanium oxide exhibits the most intense diffraction peak attributed to rutile-type titanium oxide having a full width at half maximum of 0.65° or less, in a Cu—Kα line X-ray diffraction pattern, which is obtained by plotting intensity of diffraction line with respect to diffraction angle 2θ. The composition exhibits excellent anti-viral property under light and in the dark, and excellent organic compound degradability under light.

Abstract translation: 本发明的含有Cu和Ti的组合物含有包括金红石型氧化钛的二氧化钛和二价铜化合物，其中金红石型氧化钛表现出金红石型的最强衍射峰 在Cu-Kα线X射线衍射图中，通过绘制衍射线的强度相对于衍射角2＆gt;得到的，具有半峰全宽度为0.65°以下的氧化钛。 该组合物在光和黑暗下表现出优异的抗病毒性能，并且在光照下具有优异的有机化合物降解性。