公开(公告)号：US20120302731A1

公开(公告)日：2012-11-29

申请号：US13522306

申请日：2010-10-14

Applicant: Lin Li ,  Bing Li ,  Yingjuan Tian ,  Ling Chen ,  Liang Zhu ,  Guoqin Liu ,  Jianyu Su ,  Xiaoxi Li

Inventor： Lin Li ,  Bing Li ,  Yingjuan Tian ,  Ling Chen ,  Liang Zhu ,  Guoqin Liu ,  Jianyu Su ,  Xiaoxi Li

IPC: C07K2/00 ,  C07K1/34 ,  C12P21/06

CPC classification number: C12P21/06 ,  A23J3/34 ,  A61K38/00 ,  C07K2319/00 ,  C12F3/06

Abstract: The present invention provides methods for the preparation of protein hydrolysate, peptide solution and peptide from BSG. The wet BSG or BSG powder is dispersed in extract solution to prepare the crude BSG protein or the crude BSG protein solution. Preparing the crude BSG protein solution using the crude BSG protein and adjusting the pH to 6.5˜8.5, or adjusting the pH of the crude BSG protein solution to 6.5˜8.5. Then the solution is hydrolyzed with protease at 45° C. to 65° C. for 1 h to 5 h in a water bath shaker to prepare BSG protein hydrolysate. The protein hydrolysate is heated to inactivate the protease and centrifuged to obtain the peptide solution. The peptide solution is separated by gel filtration and each peak is collected and pooled together to obtain the peptide. The protein hydrolysate, peptide solution and peptide in the present invention are all prepared from BSG which is a natural product and available at low cost throughout the year. There is no harmful material used in the production process. The results of in vitro experiment suggest that BSG peptide prepared by this method shows a significantly hypoglycemic effect.

Abstract translation: 本发明提供了从BSG制备蛋白质水解物，肽溶液和肽的方法。 将湿BSG或BSG粉末分散在提取液中以制备粗BSG蛋白或粗BSG蛋白溶液。 使用粗BSG蛋白制备粗BSG蛋白溶液并调节pH至6.5〜8.5，或将粗BSG蛋白溶液的pH调节至6.5〜8.5。 然后将溶液在45℃至65℃下用蛋白酶在水浴摇床中水解1小时至5小时以制备BSG蛋白水解产物。 将蛋白质水解产物加热灭活蛋白酶并离心得到肽溶液。 通过凝胶过滤分离肽溶液，并收集每个峰并将其汇合在一起以获得肽。 本发明中的蛋白质水解物，肽溶液和肽均由天然产物BSG制备，全年以低成本获得。 在生产过程中没有使用有害物质。 体外实验结果表明，通过该方法制备的BSG肽显示出明显的降血糖作用。

公开(公告)号：US20120289433A1

公开(公告)日：2012-11-15

申请号：US13462271

申请日：2012-05-02

Applicant: Zhuying Wang ,  Weiming Jiang ,  Jinyu Yang ,  Lin Li ,  Tao Bai

Inventor： Zhuying Wang ,  Weiming Jiang ,  Jinyu Yang ,  Lin Li ,  Tao Bai

IPC: C40B60/14 ,  C12M1/42 ,  G01N33/53 ,  G01N1/44 ,  C12M3/00 ,  C07K1/04 ,  C07H21/00 ,  B01J19/00 ,  B01J19/12 ,  C40B50/14 ,  C07K2/00

CPC classification number: C07K1/047 ,  B01L3/5085 ,  B01L2200/025 ,  B01L2200/0689 ,  B01L2200/12 ,  B01L2300/0851 ,  B01L2300/12 ,  C07K1/045

Abstract: An apparatus for forming a surface reservoir to hold a sample for a desirable period of time is described. The apparatus contains a platform, a solid surface disposed onto the platform, and an assembly of a bottomless vessel mounted on the solid surface. Also described is an apparatus that forms an array of surface reservoirs on a solid surface when multiple bottomless vessels are used, which can be used for high throughput applications. The apparatus can be used in applications on a solid surface, such as immunohistochemistry (IHC), oligo synthesis, peptide synthesis, ELISA, DNA array, peptide array, protein array, antibody array, tissue array, cell culturing, etc.

Abstract translation: 描述了一种用于形成用于将样品保持在期望时间段的表面储存器的装置。 该装置包括平台，设置在平台上的实心表面和安装在固体表面上的无底容器的组件。 还描述了当使用多个无底容器时在固体表面上形成表面储存器阵列的装置，其可用于高通量应用。 该装置可用于固体表面的应用，如免疫组化（IHC），寡聚合，肽合成，ELISA，DNA阵列，肽阵列，蛋白质阵列，抗体阵列，组织阵列，细胞培养等。

公开(公告)号：US08149164B2

公开(公告)日：2012-04-03

申请号：US12650154

申请日：2009-12-30

Applicant: Xiaoguang Yu ,  Haiquan Huang ,  Jinghua Zou ,  Lin Li ,  Bo Yu ,  Weihua Zhang ,  Lie Lu

Inventor： Xiaoguang Yu ,  Haiquan Huang ,  Jinghua Zou ,  Lin Li ,  Bo Yu ,  Weihua Zhang ,  Lie Lu

IPC: G01S19/37

CPC classification number: G01S19/24

Abstract: A signal processing system for demodulating navigation bits from a satellite signal is disclosed herein. The signal processing system includes a digital baseband processor for determining a boundary between two navigation bits in the navigation bits according to a first plurality of coarse acquisition (C/A) codes captured from the satellite signals, storing the first plurality of C/A codes, and demodulating a second plurality of C/A codes captured after determining the boundary to recover a first series of the navigation bits. The signal processing system further includes a complementary demodulating unit coupled to the digital baseband processor for demodulating the first plurality of C/A codes to recover a second series of the navigation bits.

Abstract translation: 本文公开了一种用于从卫星信号解调导航比特的信号处理系统。 信号处理系统包括数字基带处理器，用于根据从卫星信号捕获的第一多个粗略采集（C / A）码来确定导航比特中两个导航比特之间的边界，存储第一多个C / A码 并且解调在确定所述边界之后捕获的第二多个C / A码，以恢复所述导航比特的第一系列。 信号处理系统还包括一个互补解调单元，耦合到数字基带处理器，用于解调第一多个C / A码，以恢复第二系列导航位。

公开(公告)号：US20120074042A1

公开(公告)日：2012-03-29

申请号：US12889715

申请日：2010-09-24

Applicant: Shabbir Husain ,  Lin Li ,  Zhen Zhou ,  Alexander E. Kuperman ,  Zunqing He ,  Huping Luo

Inventor： Shabbir Husain ,  Lin Li ,  Zhen Zhou ,  Alexander E. Kuperman ,  Zunqing He ,  Huping Luo

IPC: C10G29/04

CPC classification number: C10G29/00 ,  C10G29/04 ,  C10G29/06 ,  C10G2300/1011 ,  C10G2300/1033 ,  C10G2300/107 ,  C10G2300/1074 ,  C10G2300/1077 ,  C10G2300/203 ,  C10G2300/4018 ,  Y02P30/20

Abstract: Disclosed are embodiments relating to a process for reducing the total acid number of a hydrocarbon feed by contacting the feed with a metal titanate catalyst having an MTiO3 structure wherein M is a metal having a valence of 2+, resulting in a hydrocarbon product having a final total acid number lower than the initial total acid number of the feed. The process is useful for pretreating high acid crudes prior to further processing thus avoiding corrosion of equipment used in refining operations. The process can be integrated into conventional refining operations in order to treat various refinery streams. In one embodiment, a process is provided for refining a low acid crude oil and a high acid crude oil by separately introducing a relatively low acid crude oil feed and a relatively high acid crude oil feed to an atmospheric distillation column, wherein the relatively high acid crude oil feed is contacted with a metal titanate catalyst prior to introduction to the atmospheric distillation column.

Abstract translation: 公开了通过使进料与具有MTiO 3结构的金属钛酸酯催化剂接触来降低烃进料的总酸值的方法的实施方案，其中M是具有2+价数的金属，导致烃产物具有最终的 总酸值低于进料的初始总酸值。 该方法可用于在进一步加工之前预处理高酸性原油，从而避免在精炼操作中使用的设备的腐蚀。 该方法可以集成到常规的精炼操作中，以便处理各种炼油流。 在一个实施方案中，提供了通过将相对低的酸性原油进料和相对高的酸性原油进料单独引入常压蒸馏塔来提炼低酸原油和高酸性原油的方法，其中相对高的酸 原油进料在引入常压蒸馏塔之前与钛酸金属催化剂接触。

公开(公告)号：US08064943B2

公开(公告)日：2011-11-22

申请号：US12235188

申请日：2008-09-22

Applicant: Lin Li ,  Xugang Wu ,  Shengting Zhang ,  Zheng Wang

Inventor： Lin Li ,  Xugang Wu ,  Shengting Zhang ,  Zheng Wang

IPC: H04Q7/20

CPC classification number: H04L65/4061 ,  H04L65/1006 ,  H04W4/08 ,  H04W4/10 ,  H04W8/186 ,  H04W76/45

Abstract: The present invention discloses a method and an apparatus for controlling user's participation into a session so that the system can control accession to a PoC session requested by anonymous users and restrict an expelled user from joining the session again. Under the present invention, a client in the PoC session sends a request of expelling a user to the control server, with the SSRC identifier or nickname of the user or an anonymous user wildcard carried in the request; according to the received SSRC identifier, nickname or anonymous user wildcard, the control server searches for the corresponding PoC address, and expels the user out of the session as required according to the PoC address. Therefore, the client with the expulsion right can control accession to the PoC session requested by other users, especially anonymous users, thus keeping order of the session. The control server automatically rejects the reattempt of the expelled user according to the rejection list and the rejection policy, thus preventing such users from harassing the PoC session maliciously, and improving the service experience of the user.

Abstract translation: 本发明公开了一种用于控制用户参与会话的方法和装置，使得系统可以控制对匿名用户请求的PoC会话的加入，并限制被驱逐的用户再次加入该会话。 在本发明中，PoC会话中的客户端发送请求，该请求将用户的SSRC标识符或昵称或者请求中携带的匿名用户通配符发送到控制服务器; 根据接收到的SSRC标识符，昵称或匿名用户通配符，控制服务器搜索相应的PoC地址，并根据PoC地址根据需要将用户排除在会话之外。 因此，具有驱逐权限的客户端可以控制对其他用户特别是匿名用户请求的PoC会话的加入，从而保持会话顺序。 控制服务器根据拒绝列表和拒绝策略自动拒绝对被驱逐的用户的重试，从而防止这些用户恶意地骚扰PoC会话，并改善用户的服务体验。

公开(公告)号：US20110203973A1

公开(公告)日：2011-08-25

申请号：US12711124

申请日：2010-02-23

Applicant: Lin Li ,  Hua-Min Huang ,  Zunqing He

Inventor： Lin Li ,  Hua-Min Huang ,  Zunqing He

IPC: C10C1/20 ,  C10G1/00 ,  C10C3/02

CPC classification number: C10G31/08 ,  C10G2300/1033 ,  C10G2300/1074 ,  C10G2300/1077 ,  C10G2300/308 ,  C10G2300/805

Abstract: A process is disclosed using a dispersion of supercritical fluid and oil to upgrade a hydrocarbon feedstock such as a heavy oil into an upgraded hydrocarbon product or synthetic crude with highly desirable properties such as low sulfur content, low metals content, lower density (higher API), lower viscosity, lower residuum content, etc. The process utilizes a capillary mixer to form the dispersion. The process does not require external supply of hydrogen nor does it use externally supplied catalysts.

Abstract translation: 公开了一种使用超临界流体和油的分散体将烃原料如重油升级成升级的烃产物或合成粗品的方法，其具有高度期望的性能，例如低硫含量，低金属含量，较低密度（较高的API） ，较低的粘度，较低的渣油含量等。该方法利用毛细管混合器形成分散体。 该方法不需要外部氢气供应，也不需要使用外部供应的催化剂。

公开(公告)号：US07986400B2

公开(公告)日：2011-07-26

申请号：US13034539

申请日：2011-02-24

Applicant: Richard Karl Fenrich ,  Lin Li

Inventor： Richard Karl Fenrich ,  Lin Li

IPC: G06K9/74

CPC classification number: G06K9/00046

Abstract: A fingerprint imaging system configured to capture an image of a friction ridge pattern of a subject (e.g., a fingerprint, a palm print, a hand print, a footprint, etc.). The system may include one or more components that reduce the impact of ambient light on the performance of the system. In some implementations, the system may reduce the impact of ambient light without requiring additional power (e.g., to generate an increased amount of radiation) and without including “external” hoods and/or covers designed to block ambient light prior to the ambient light entering system. Instead, the system may reduce the impact of ambient light on performance by blocking ambient light internally within the system along an optical path of radiation used to electronically capture an image of the friction ridge pattern.

Abstract translation: 一种被配置为捕获被摄体的摩擦脊图案（例如，指纹，手掌印刷，手印，印记等）的图像的指纹成像系统。 该系统可以包括减少环境光对系统性能的影响的一个或多个组件。 在一些实施方案中，系统可以减少环境光的影响，而不需要额外的功率（例如，产生增加的辐射量），并且不包括设计成在环境光进入之前阻挡环境光的“外部”罩和/或盖 系统。 相反，系统可以通过沿着用于电子捕获摩擦脊图案的图像的辐射光路阻挡系统内的环境光来减小环境光对性能的影响。

公开(公告)号：US07964883B2

公开(公告)日：2011-06-21

申请号：US10788116

申请日：2004-02-26

Applicant: Joseph Mazzochette ,  Edmar Amaya ,  Lin Li ,  Greg E. Blonder

Inventor： Joseph Mazzochette ,  Edmar Amaya ,  Lin Li ,  Greg E. Blonder

IPC: H01L33/00

CPC classification number: F21V29/89 ,  F21K9/68 ,  F21V29/70 ,  F21Y2107/90 ,  F21Y2115/10 ,  H01L2224/45144 ,  H01L2224/48091 ,  H01L2224/48465 ,  H01L2924/19107 ,  H05K1/053 ,  H01L2924/00014 ,  H01L2924/00

Abstract: In accordance with the invention, a light emitting diode package assembly is provided to emulate the pattern of light produced by an incandescent filament bulb. The package assembly is composed of a substrate for LEDs comprising a heat-sinking base having a pair of opposing major surfaces. Each major surface has an overlying of thermally conducting ceramic and an outer surface layer of light reflective material. Disposed on each surface layer is a plurality of LEDs. Advantageously, the LEDs are arranged on the surface in a configuration of low mutual obstruction. Advantageously, reflecting elements transverse to each surface layer are positioned and shaped to reflect a substantial portion of the light emitted from the LEDs that would otherwise enter neighboring LEDs. In a preferred embodiment, the LEDs are arranged in the general form of a closed curve, and a transverse reflector is disposed in the interior of the curve. Alternatively, the LEDs can be arranged in a linear array. The assembly can be efficiently fabricated by back-to-back assembly of two similar subassemblies.

Abstract translation: 根据本发明，提供一种发光二极管封装组件以模拟由白炽灯丝灯泡产生的光的图案。 封装组件由用于LED的衬底组成，其包括具有一对相对的主表面的散热底座。 每个主表面具有覆盖导热陶瓷和光反射材料的外表面层。 在每个表面层上设置有多个LED。 有利地，LED以低相互阻塞的构造布置在表面上。 有利地，横向于每个表面层的反射元件被定位和成形以反射从LED发射的光的相当大部分，否则其将进入相邻的LED。 在优选实施例中，LED以闭合曲线的一般形式布置，并且横向反射器设置在曲线的内部。 或者，LED可以以线性阵列布置。 可以通过两个相似的子组件的背靠背组装来有效地制造组件。

公开(公告)号：US07884211B2

公开(公告)日：2011-02-08

申请号：US12509218

申请日：2009-07-24

Applicant: Patrick G. Harran ,  Xiaodong Wang ,  Jef K. De Brabander ,  Lin Li ,  Ranny Mathew Thomas ,  Hidetaka Suzuki

Inventor： Patrick G. Harran ,  Xiaodong Wang ,  Jef K. De Brabander ,  Lin Li ,  Ranny Mathew Thomas ,  Hidetaka Suzuki

IPC: C07D249/04 ,  A61K31/42

CPC classification number: C07D413/14 ,  A61K31/41 ,  A61K31/422 ,  C07D207/08 ,  C07D401/10 ,  C07D403/10 ,  C07D403/14 ,  C07D405/10 ,  C07D409/10 ,  C07D413/04 ,  C07D413/06 ,  C07D413/10 ,  C07D417/04 ,  C07D417/10 ,  C07D417/14 ,  C07D495/04 ,  C07K5/06026 ,  C07K5/06034

Abstract: Caspase activity and apoptosis are promoted using active, dimeric Smac peptide mimetics of the general formula M1-L-M2, wherein moieties M1 and M2 are monomeric Smac mimetics and L is a covalent linker. Target cancerous or inflammatory cells are contacted with an effective amount of an active, dimeric Smac mimetic, and a resultant increase in apoptosis of the target cells is detected. The contacting step may be effected by administering to a pharmaceutical composition comprising a therapeutically effective amount of The compoundic mimetic, wherein the individual may be subject to concurrent or antecedent radiation or chemotherapy for treatment of a neoproliferative pathology.

Abstract translation: 使用通式M1-L-M2的活性二聚体Smac肽模拟物促进胱天蛋白酶活性和凋亡，其中部分M1和M2是单体Smac模拟物，L是共价连接体。 靶向癌性或炎性细胞与有效量的活性二聚体Smac模拟物接触，并且检测到靶细胞凋亡的最终增加。 接触步骤可以通过给予包含治疗有效量的复合模拟物的药物组合物来实现，其中个体可以同时或先前放射或化疗用于治疗新生血管病变。

公开(公告)号：US20100014027A1

公开(公告)日：2010-01-21

申请号：US12504128

申请日：2009-07-16

Applicant: Lin Li ,  Israel J. Morejon

Inventor： Lin Li ,  Israel J. Morejon

IPC: G02F1/13357

CPC classification number: G02B6/0028 ,  G02B6/0036 ,  G02B6/0046 ,  G02B6/0068 ,  G02B6/0073 ,  G02F1/133615

Abstract: One or more embodiments of the present invention provide apparatuses and systems to form edge-illuminated LED backlight units for flat-panel LCD displays. The backlight unit is able to achieve uniform color and brightness distribution with very small dimensions of depth and bezels. One or more embodiments of the present invention include a light guide coupled to a light guide plate, which, by operating together, provide simple, efficient, few LEDs and low cost backlight units. Effective coupling structures provide high system efficiency.

Abstract translation: 本发明的一个或多个实施例提供了用于形成用于平板LCD显示器的边缘照明LED背光单元的设备和系统。 背光单元能够以非常小的深度和边框尺寸实现均匀的颜色和亮度分布。 本发明的一个或多个实施例包括耦合到导光板的光导，其通过一起操作来提供简单，有效的，少量的LED和低成本的背光单元。 有效的耦合结构提供高系统效率。