公开(公告)号：US07010080B2

公开(公告)日：2006-03-07

申请号：US10850499

申请日：2004-05-20

Applicant: Matthias Mitschke ,  Norbert Rahn ,  Dieter Ritter

Inventor： Matthias Mitschke ,  Norbert Rahn ,  Dieter Ritter

IPC: A61B6/03

CPC classification number: A61B6/547 ,  A61B6/12 ,  A61B6/4441 ,  A61B6/504 ,  A61B6/5235 ,  A61B6/5247 ,  G06T7/38 ,  G06T2207/30004 ,  Y10S378/901

Abstract: In a method and apparatus for automatic marker-free fusion (matching) of 2D fluoroscopic C-arm images with preoperative 3D images using an intraoperatively acquired 3D data record, an intraoperative 3D image is obtained using a C-arm x-ray system, image-based matching of an existing preoperative 3D image in relation to the intraoperative 3D image is undertaken, which generates a matching matrix of a tool plate attached to the C-arm system is matched in relation to a navigation system, a 2D fluoroscopic image to be matched is obtained, with the C-arm of the C-arm system in any arbitrary location, a projection matrix for matching the 2D fluoroscopic image in relation to the 3D image is obtained, and the 2D fluoroscopic image is fused (matched) with the preoperative 3D image on the basis of the matching matrix and the projection matrix.

Abstract translation: 在使用手术中获取的3D数据记录的2D荧光镜C臂图像与术前3D图像进行自动无标记融合（匹配）的方法和装置中，使用C臂x射线系统获得术中3D图像，图像 进行与术中3D图像相关的现有术前3D图像的匹配，其生成附接到C臂系统的工具板的匹配矩阵相对于导航系统匹配，2D透视图像为 获得与C臂系统的C臂在任意位置匹配的匹配，获得与3D图像相匹配的2D透视图像的投影矩阵，并将2D透视图像与 基于匹配矩阵和投影矩阵的术前3D图像。

公开(公告)号：US20050203420A1

公开(公告)日：2005-09-15

申请号：US11007492

申请日：2004-12-08

Applicant: Martin Kleen ,  Marcus Pfister ,  Norbert Rahn

Inventor： Martin Kleen ,  Marcus Pfister ,  Norbert Rahn

IPC: G01N21/64 ,  A61B1/00 ,  A61B5/00 ,  A61B5/055 ,  A61B6/03 ,  A61B8/00 ,  G06T1/00 ,  G06T7/00 ,  A61B6/00

CPC classification number: A61B5/0073 ,  A61B5/0071 ,  A61B5/0084 ,  A61B5/055 ,  A61B6/032 ,  A61B6/5247 ,  A61B8/00 ,  A61B8/5238 ,  G06K9/32 ,  G06K2209/05 ,  G06T7/38

Abstract: The invention relates to a method for the merged display of first image information captured using a first imaging device with second image information captured using a second imaging device, whereby said image information relates to the same area of examination in the human or animal body, in particular a hollow organ, in which method: a plurality of individual, two-dimensional images of the area under examination are recorded in the form of fluorescence images by light-excitation of fluorescent areas of the area under examination, using a medical instrument to be introduced invasively into the area under examination, in particular a catheter, a 3D fluorescence image data record, suitable for the three-dimensional reconstruction of a fluorescence three-dimensional image of the area under examination, is generated from the individual two-dimensional images, a further 3D image data record of the area under examination recorded using a further examination procedure, said further 3D image data record being suitable for the three-dimensional reconstruction of a further three-dimensional image of the area under examination, is used, the 3D fluorescence image data record and the further 3D image data record are registered with one another, and one or more fluorescence-optically marked, relevant areas of the examination volume, on the basis of the mapping rules determined by the registration process, are displayed on a monitor, said areas being accurately positioned in the further three-dimensional image generated using the further 3D data record, whereby either a) one or more fluorescence-optically marked, relevant areas of the area under examination are identified in the 3D fluorescence image data record in terms of their spatial position, and only these extracted partial image areas are displayed, said extracted partial image areas being accurately positioned in the further three-dimensional image, or b) the complete fluorescence three-dimensional image is superimposed over the further three-dimensional image, with voxels having predefined gray-scale values being masked out.

公开(公告)号：US20050165303A1

公开(公告)日：2005-07-28

申请号：US11012971

申请日：2004-12-14

Applicant: Martin Kleen ,  Marcus Pfister ,  Norbert Rahn

Inventor： Martin Kleen ,  Marcus Pfister ,  Norbert Rahn

IPC: G01N21/64 ,  A61B1/00 ,  A61B5/00 ,  A61B5/06 ,  A61B19/00 ,  A61M25/00 ,  A61B5/05

CPC classification number: A61B5/0071 ,  A61B5/0073 ,  A61B5/0084 ,  A61B5/06 ,  A61B5/062 ,  A61B5/7285 ,  A61B34/20 ,  A61B90/36 ,  A61B90/361 ,  A61B2034/2051 ,  A61B2090/367 ,  A61B2090/373

Abstract: Catheter device comprising a catheter, in particular an intravascular catheter, for insertion into an area being examined, in particular into a vessel or cavity-containing organ in the body of a person or animal, wherein in the area of the catheter tip a device (3) is provided for emitting excitation light for light-optically exciting an area being examined surrounding said catheter tip, furthermore a device (3) is provided for collecting response light emitted, owing to excitation, from the area being examined, and furthermore a position sensor (13, 24, 27) is provided enabling said catheter tip's spatial position and/or orientation to be registered in a system of coordinates of a position-registering system (7, 14).

Abstract translation: 导管装置，其包括导管，特别是血管内导管，用于插入被检查的区域，特别是插入人或动物身体中的血管或含空腔的器官中，其中在导管末端的区域中， 3）用于发射用于光学激发围绕所述导管尖端的被检查区域的激发光，此外，设备（3）用于从被检查的区域收集由于激发而发射的响应光，并且还提供位置 传感器（13,24,27）被设置成能够使所述导管尖端的空间位置和/或取向登记在位置登记系统（7,14）的坐标系中。

公开(公告)号：US20050027193A1

公开(公告)日：2005-02-03

申请号：US10851259

申请日：2004-05-21

Applicant: Matthias Mitschke ,  Norbert Rahn ,  Dieter Ritter

Inventor： Matthias Mitschke ,  Norbert Rahn ,  Dieter Ritter

IPC: A61B5/05 ,  A61B19/00 ,  G06T7/00 ,  G06T17/00

CPC classification number: A61B34/20 ,  A61B6/12 ,  A61B6/4441 ,  A61B2090/364 ,  A61B2090/365 ,  A61B2090/376 ,  G06T7/33 ,  G06T7/38 ,  G06T2207/30004

Abstract: In a method and apparatus for the automatic merging of 2D fluoroscopic C-arm images with preoperative 3D images with a one-time use of navigation markers, markers in a marker-containing preoperative 3D image are registered relative to a navigation system, a tool plate fixed on the C-arm system is registered in a reference position relative to the navigation system, a 2D C-arm image (2D fluoroscopic image) that contains the image of at least a medical instrument is obtained in an arbitrary C-arm position, a projection matrix for a 2D-3D merge is determined on the basis of the tool plate and the reference position relative to the navigation system, and the 2D fluoroscopic image is superimposed with the 3D image on the basis of the projection matrix.

Abstract translation: 在一次性使用导航标记的2D透视C臂图像与术前3D图像的自动合并的方法和装置中，包含标记的术前3D图像中的标记相对于导航系统，工具板 在C臂系统上固定的参考位置相对于导航系统被记录在参考位置，在任意C臂位置处获得包含至少医疗器械的图像的2D C臂图像（2D透视图像） 基于工具板和相对于导航系统的参考位置确定用于2D-3D合并的投影矩阵，并且基于投影矩阵将2D透视图像与3D图像叠加。

公开(公告)号：US20050004454A1

公开(公告)日：2005-01-06

申请号：US10850499

申请日：2004-05-20

Applicant: Matthias Mitschke ,  Norbert Rahn ,  Dieter Ritter

Inventor： Matthias Mitschke ,  Norbert Rahn ,  Dieter Ritter

IPC: A61B6/00 ,  A61B6/12 ,  G06T7/00 ,  A61B5/05

CPC classification number: A61B6/547 ,  A61B6/12 ,  A61B6/4441 ,  A61B6/504 ,  A61B6/5235 ,  A61B6/5247 ,  G06T7/38 ,  G06T2207/30004 ,  Y10S378/901

Abstract: In a method and apparatus for automatic marker-free fusion (matching) of 2D fluoroscopic C-arm images with preoperative 3D images using an intraoperatively acquired 3D data record, an intraoperative 3D image is obtained using a C-arm x-ray system, image-based matching of an existing preoperative 3D image in relation to the intraoperative 3D image is undertaken, which generates a matching matrix of a tool plate attached to the C-arm system is matched in relation to a navigation system, a 2D fluoroscopic image to be matched is obtained, with the C-arm of the C-arm system in any arbitrary location, a projection matrix for matching the 2D fluoroscopic image in relation to the 3D image is obtained, and the 2D fluoroscopic image is fused (matched) with the preoperative 3D image on the basis of the matching matrix and the projection matrix.

Abstract translation: 在使用手术中获取的3D数据记录的2D荧光镜C臂图像与术前3D图像进行自动无标记融合（匹配）的方法和装置中，使用C臂x射线系统获得术中3D图像，图像 进行与术中3D图像相关的现有术前3D图像的匹配，其生成附接到C臂系统的工具板的匹配矩阵相对于导航系统匹配，2D透视图像为 获得与C臂系统的C臂在任意位置匹配的匹配，获得与3D图像相匹配的2D透视图像的投影矩阵，并将2D透视图像与 基于匹配矩阵和投影矩阵的术前3D图像。

公开(公告)号：US06806864B2

公开(公告)日：2004-10-19

申请号：US09726408

申请日：2000-12-01

Applicant: Norbert Rahn ,  Siegfried Wach

Inventor： Norbert Rahn ,  Siegfried Wach

IPC: G09G508

CPC classification number: G06F3/043 ,  A61B5/742 ,  A61B6/03 ,  A61B6/463 ,  A61B8/00 ,  G06F3/033 ,  G06F3/0346 ,  G06F3/04845

Abstract: An operating device for influencing medical image information items displayed at a display surface with a movable operating element has a motion acquisition system for quantitatively determining adjustment motions of the operating element, with the representation of the image information items displayed at the display surface being influenced solely by motions of the operating element.

Abstract translation: 用于影响在可移动操作元件上显示在显示表面上的医用图像信息项的操作装置具有用于定量地确定操作元件的调节运动的运动采集系统，显示表面上显示的图像信息项的表示仅仅受到影响 通过操作元件的运动。

公开(公告)号：US06359960B1

公开(公告)日：2002-03-19

申请号：US09630968

申请日：2000-08-02

Applicant: Eric Wahl ,  Uwe Weber ,  Norbert Rahn ,  Rainer Graumann

Inventor： Eric Wahl ,  Uwe Weber ,  Norbert Rahn ,  Rainer Graumann

IPC: A61B603

CPC classification number: G06T7/66 ,  A61B6/12 ,  G06T7/70 ,  G06T2207/30016

Abstract: In a method for automatically determining coordinates, relative to a reference coordinate system, of markers contained in a 3D volume data set of a subject provided with markers imaged in 2D projections of the 3D volume data set are detected, the centers of gravity of the imaged markers are determined, and back projection straight lines through the markers are established. The intersection points of the back projection straight lines with each other are identified, or the points with the smallest distance from one another on different back projection straight lines are determined if the back projection lines arc skewed. Spatially limited areas are identified, which contain an accumulation of intersection points of back projection straight lines or an accumulation of points with the smallest distance from one another. The coordinates of the centers of gravity of these spatially limited areas are calculated and are used as the coordinates for the respective markers.

Abstract translation: 在用于自动确定相对于参考坐标系的坐标的方法中，检测包含在设置有3D体积数据集的2D投影中的标记的受试者的3D体积数据集中的标记的坐标，所成像的重心 确定标记，建立通过标记的背投直线。 识别背投直线的交点，或者如果背投影线歪斜，则确定在不同背投直线上彼此之间具有最小距离的点。 识别空间有限的区域，其包含背投影直线的交叉点的累积或彼此具有最小距离的点的累积。 计算这些空间受限区域的重心的坐标，并将其用作相应标记的坐标。

公开(公告)号：US09668704B2

公开(公告)日：2017-06-06

申请号：US10569957

申请日：2004-08-24

Applicant: Kristine Fuimaono ,  Gal Hayam ,  Yuval Karmi ,  Reinmar Killmann ,  Assaf Preiss ,  Norbert Rahn ,  Frank Sauer ,  Chenyang Xu

Inventor： Kristine Fuimaono ,  Gal Hayam ,  Yuval Karmi ,  Reinmar Killmann ,  Assaf Preiss ,  Norbert Rahn ,  Frank Sauer ,  Chenyang Xu

IPC: A61B5/05 ,  A61B6/03 ,  A61B5/055 ,  A61B8/14 ,  A61B5/00 ,  A61B6/00 ,  A61B8/00 ,  A61B18/14 ,  A61B18/00 ,  G01R33/56

CPC classification number: A61B6/032 ,  A61B5/055 ,  A61B5/7285 ,  A61B6/541 ,  A61B8/14 ,  A61B8/543 ,  A61B18/1492 ,  A61B2018/00375 ,  A61B2018/00839 ,  G01R33/5608

Abstract: The invention relates to a device and to a method for visual assistance during the electrophysiological use of a catheter in the heart, enabling electroanatomic 3D mapping data relating to an area of the heart to be treated to be visualized during the use of the catheter. Before the catheter is used, 3D image data of a body region containing the area to be treated is detected by means of a method for tomographic 3D imaging. The area to be treated or significant parts thereof are extracted from said 3D image data, in order to obtain selected 3D image data. The electroanatomic 3D mapping data and the selected 3D image data obtained are then classed in terms of position and dimension, and are adjacently visualized, for example, during the catheter ablation. The inventive method and associated device enable the orientation of the operator to be improved during the use of a catheter in the heart.

公开(公告)号：US09078567B2

公开(公告)日：2015-07-14

申请号：US10569958

申请日：2004-08-19

Applicant: Kristine Fuimaono ,  Gal Hayam ,  Yuval Karmi ,  Reinmar Killmann ,  Assaf Preiss ,  Norbert Rahn ,  Frank Sauer ,  Chenyang Xu

Inventor： Kristine Fuimaono ,  Gal Hayam ,  Yuval Karmi ,  Reinmar Killmann ,  Assaf Preiss ,  Norbert Rahn ,  Frank Sauer ,  Chenyang Xu

IPC: A61B5/05 ,  A61B6/03 ,  A61B5/055 ,  A61B8/14 ,  A61B5/00 ,  A61B6/00 ,  A61B8/00 ,  A61B18/14 ,  A61B18/00 ,  G01R33/56

CPC classification number: A61B6/032 ,  A61B5/055 ,  A61B5/7285 ,  A61B6/5247 ,  A61B6/541 ,  A61B8/14 ,  A61B8/543 ,  A61B18/1492 ,  A61B2018/00375 ,  A61B2018/00839 ,  G01R33/5608

Abstract: The invention relates to a method and a device for visually supporting an electrophysiology catheter application in the heart, whereby electroanatomical 3D mapping data of an area of the heart to be treated which are provided during performance of the catheter application are visualized. Before the catheter application is carried out, 3D image data of the area to be treated are recorded by means of a tomographical 3D imaging method, a 3D surface profile of objects in the area to be treated is extracted from the 3D image data by segmentation and the electroanatomical 3D mapping data provided and the 3D images representing the 3D surface profile are associated with each other in the correct position and dimension relative each other and e.g. visualized in an superimposed manner during the catheter application. The present method and the corresponding device allow for an improved orientation of the user who carries out an electrophysiology catheter application in the heart.

Abstract translation: 本发明涉及用于视觉上支持心脏中的电生理学导管应用的方法和装置，由此可视化在执行导管应用过程中提供的待治疗心脏区域的电解剖3D绘图数据。 在执行导管应用之前，通过断层3D成像方法记录待处理区域的3D图像数据，通过分割从3D图像数据中提取待处理区域中的对象的3D表面轮廓， 所提供的电解剖3D图形数据和表示3D表面轮廓的3D图像彼此相对彼此相关联，并且例如彼此相对。 在导管应用期间以叠加的方式显现。 本方法和相应的装置允许在心脏中进行电生理学导管应用的用户的改进的取向。

公开(公告)号：US08195271B2

公开(公告)日：2012-06-05

申请号：US11983027

申请日：2007-11-06

Applicant: Norbert Rahn

Inventor： Norbert Rahn

IPC: A61B5/055 ,  A61B6/00

CPC classification number: A61B6/12 ,  A61B5/7289 ,  A61B18/1492 ,  A61B34/25 ,  A61B34/30 ,  A61B90/361 ,  A61B2018/00351 ,  A61B2018/00839 ,  A61B2034/2051 ,  A61B2034/2063 ,  A61B2034/301 ,  A61B2090/3762

Abstract: A system and method of treating tachycardias and similar syndromes by the use of catheter ablation of tissue is described. A computed tomography (CT)-like image of the heart is obtained and processed to segment the various types of tissue. Papillary muscle areas are identified and displayed differently from the other nearby tissues so that the muscles can be avoided during treatment to avoid or minimize damage to the muscles during ablation treatment. Electrophysical data and scar tissue may also be identified in the image, which may be of the endoscopic type. The position of the catheter may be displayed as a synthetic image on the endoscopic view.

Abstract translation: 描述了通过使用导管消融组织治疗心动过速和类似综合征的系统和方法。 获得心脏的计算机断层摄影（CT）样图像并进行处理以分割各种类型的组织。 识别和显示乳头肌区域与其他附近组织不同，使得在治疗期间可以避免肌肉以避免或最小化在消融治疗期间对肌肉的损伤。 也可以在图像中识别电物理数据和瘢痕组织，其可以是内窥镜型。 导管的位置可以在内窥镜视图上显示为合成图像。