公开(公告)号：US20100234578A1

公开(公告)日：2010-09-16

申请号：US12729997

申请日：2010-03-23

申请人： Toshifumi Mikayama ,  Hitoshi Yoshida ,  Walker R. Force ,  Xingjie Chen ,  Nobuaki Takahashi

发明人： Toshifumi Mikayama ,  Hitoshi Yoshida ,  Walker R. Force ,  Xingjie Chen ,  Nobuaki Takahashi

IPC分类号： C07K16/18

CPC分类号： C07K16/2878 ,  A61K2039/505 ,  C07K2317/21 ,  C07K2319/00 ,  C07K2319/30

摘要： An antibody or a functional fragment thereof, acting agonistically or antagonistically on CD40.

摘要翻译： 一种抗体或其功能片段，在CD40上起激动作用或拮抗作用。

公开(公告)号：US20100171804A1

公开(公告)日：2010-07-08

申请号：US12644419

申请日：2009-12-22

申请人： Nobuaki Takahashi ,  Atsushi Kubota ,  Kazuhiko Ohtsu ,  Satoshi Kaiho ,  Takashi Kado

发明人： Nobuaki Takahashi ,  Atsushi Kubota ,  Kazuhiko Ohtsu ,  Satoshi Kaiho ,  Takashi Kado

IPC分类号： B41J2/01

CPC分类号： B41J11/0085 ,  B41J11/0025 ,  B41J11/007

摘要： An image recording apparatus includes a conveyance unit which includes a conveyance belt and an air suction unit for sucking air through the conveyance belt to adsorb a recording medium onto the conveyance belt. A recording head ejects ink to carry out recording on the recording medium conveyed by the conveyance unit. An adsorption force adjusting unit adjusts the adsorption force for the recording medium on the conveyance belt, which occurs by sucking air, according to the size of the recording medium.

摘要翻译： 图像记录装置包括输送单元，该输送单元包括输送带和吸气单元，用于通过输送带吸入空气以将记录介质吸附到输送带上。 记录头喷射墨水以在由输送单元输送的记录介质上进行记录。 吸附力调节单元根据记录介质的尺寸来调节通过吸入空气发生的输送带上的记录介质的吸附力。

公开(公告)号：US20100144091A1

公开(公告)日：2010-06-10

申请号：US12656616

申请日：2010-02-04

申请人： Masaya Kawano ,  Koji Soejima ,  Nobuaki Takahashi ,  Yoichiro Kurita ,  Masahiro Komuro ,  Satoshi Matsui

发明人： Masaya Kawano ,  Koji Soejima ,  Nobuaki Takahashi ,  Yoichiro Kurita ,  Masahiro Komuro ,  Satoshi Matsui

IPC分类号： H01L21/50

CPC分类号： H01L25/0657 ,  H01L21/76898 ,  H01L23/3128 ,  H01L23/481 ,  H01L23/562 ,  H01L23/642 ,  H01L25/50 ,  H01L2221/68345 ,  H01L2223/6622 ,  H01L2224/16145 ,  H01L2224/16225 ,  H01L2224/32225 ,  H01L2224/73204 ,  H01L2225/06513 ,  H01L2225/06517 ,  H01L2225/06524 ,  H01L2225/06541 ,  H01L2225/06572 ,  H01L2924/01046 ,  H01L2924/01078 ,  H01L2924/01079 ,  H01L2924/10155 ,  H01L2924/15311 ,  H01L2924/181 ,  H01L2924/00 ,  H01L2924/00012

摘要： A method of manufacturing a semiconductor device includes forming an interconnect member, mounting a first semiconductor chip having a semiconductor substrate in a face-down manner on the interconnect member, forming a resin layer on the interconnect member to cover a side surface of the first semiconductor chip, thinning the first semiconductor chip and the resin layer, forming an inorganic insulating layer on a back surface of the first semiconductor chip so as to be in contact with the back surface and to extend over the resin layer, and forming a through electrode so as to penetrate the inorganic insulating layer and the semiconductor substrate.

摘要翻译： 一种制造半导体器件的方法包括形成互连部件，将具有半导体衬底的第一半导体芯片以面向下的方式安装在互连部件上，在互连部件上形成树脂层以覆盖第一半导体的侧表面 芯片，使第一半导体芯片和树脂层变薄，在第一半导体芯片的背面上形成无机绝缘层，以与背面接触并延伸到树脂层上，并形成通孔，从而形成通孔 以穿透无机绝缘层和半导体衬底。

公开(公告)号：US20090199612A1

公开(公告)日：2009-08-13

申请号：US12318882

申请日：2009-01-12

申请人： Nobuaki Takahashi ,  Akio Yamamoto ,  Masahiko Hamada

发明人： Nobuaki Takahashi ,  Akio Yamamoto ,  Masahiko Hamada

IPC分类号： B21D9/00 ,  B21D9/05

CPC分类号： B21C37/08 ,  B23K33/006 ,  B23K2101/06 ,  B23K2103/04 ,  C21D9/08 ,  C21D9/50 ,  C22C38/02 ,  C22C38/04 ,  C22C38/06

摘要： A high-strength hot bend pipe which has a balance between an excellent strength of at least X70 grade and toughness and which has excellent tensile properties and a weld metal with excellent low temperature toughness is manufactured. A UOE steel pipe having a base metal with a composition of C: 0.03-0.12%, Si: 0.05-0.50%, Mn: 1.4-2.2%, S: at most 0.01%, Al: at most 0.06%, N: at most 0.008%, and a remainder of Fe and impurities, with the carbon equivalent (Ceq) being at most 0.36% and the weld cracking parameter (Pcm) being at most 0.22%, and having a weld metal with a weld cracking parameter (Pcm) of at most 0.28%, a B content of at most 5 ppm, and an O content of at most 280 ppm is heated to a temperature range of 900-1100° C. and subjected to bending, and then is immediately cooled to a temperature range of 300° C. or lower at a cooling rate of at least 3° C./sec, and then is tempered in a temperature range of 300-500° C.

摘要翻译： 制造具有至少X70等级的优异强度和具有优异的拉伸性能的优异强度与具有优异的低温韧性的焊接金属之间的平衡的高强度热弯管。 具有组成为C：0.03〜0.12％，Si：0.05〜0.50％，Mn：1.4〜2.2％，S：0.01％以下，Al：0.06％以下的贱金属的UOE钢管，N： 最多0.008％，余量为Fe和杂质，碳当量（Ceq）最大为0.36％，焊接裂纹参数（Pcm）为0.22％以下，具有焊缝裂纹参数（Pcm ）为0.28％以下，B含量为5ppm以下，O含量为280ppm以下，加热到900〜1100℃的温度范围，进行弯曲，然后立即冷却至 温度范围为300℃以下，冷却速度为3℃/秒以上，然后在300-500℃的温度范围内回火。

公开(公告)号：US07537763B2

公开(公告)日：2009-05-26

申请号：US11633716

申请日：2006-12-05

申请人： Toshifumi Mikayama ,  Hitoshi Yoshida ,  Walker R. Force ,  Xingjie Chen ,  Nobuaki Takahashi

发明人： Toshifumi Mikayama ,  Hitoshi Yoshida ,  Walker R. Force ,  Xingjie Chen ,  Nobuaki Takahashi

IPC分类号： A61K39/395 ,  C07K16/28 ,  C12N5/12 ,  C12N15/13

CPC分类号： C07K16/2878 ,  A61K2039/505 ,  C07K2317/21 ,  C07K2319/00 ,  C07K2319/30

摘要： An antibody or a functional fragment thereof, acting agonistically or antagonistically on CD40.

摘要翻译： 一种抗体或其功能片段，在CD40上起激动作用或拮抗作用。

公开(公告)号：US20080005622A1

公开(公告)日：2008-01-03

申请号：US11839994

申请日：2007-08-16

申请人： Nobuaki Takahashi ,  Takeo Nakada ,  Nobuyuki Ohba

发明人： Nobuaki Takahashi ,  Takeo Nakada ,  Nobuyuki Ohba

IPC分类号： H04L1/22 ,  G06F3/00

CPC分类号： H04L1/24 ,  H04L2001/0094

摘要： A digital signal measuring apparatus comprises a bus probe unit for extracting a bus event occurring on a bus based on a digital bus signal on the bus of the system to be measured, a traffic measuring unit for counting the number of occurrences of bus event based on the occurrence information of the extracted bus event, and a console unit for acquiring and processing the count value of the traffic measuring unit.

摘要翻译： 一种数字信号测量装置，包括：总线探测单元，用于基于待测量系统的总线上的数字总线信号，提取总线上发生的总线事件;一个业务量测量单元，用于对总线事件的发生次数进行计数，基于 所提取的总线事件的发生信息，以及用于获取和处理交通量测量单元的计数值的控制台单元。

公开(公告)号：US20070148163A1

公开(公告)日：2007-06-28

申请号：US10584345

申请日：2004-12-24

申请人： Nobuaki Takahashi ,  Toru Miura ,  Yoshinori Kitagawa ,  Aki Hirano

发明人： Nobuaki Takahashi ,  Toru Miura ,  Yoshinori Kitagawa ,  Aki Hirano

IPC分类号： A61K39/40 ,  A61K39/395 ,  A61K39/42 ,  C07H21/04 ,  C12P21/06 ,  C07K16/42 ,  C07K16/30 ,  C07K16/12 ,  C07K16/10 ,  C12N5/06

CPC分类号： C07K16/2878 ,  C07K2317/34 ,  C07K2317/52 ,  C07K2317/53 ,  C07K2317/56 ,  C07K2317/73 ,  C07K2317/732 ,  C07K2317/734 ,  C07K2317/76

摘要： A mutant of a potentially therapeutic anti-CD40 antibody is provided which mutant has reduced ADCC and CDC activities designed to be optimized as a pharmaceutical agent. A mutant of an agonistic anti-CD40 antibody, comprising mutation and/or substitution of at least one amino acid in the constant region to reduce the ADCC and/or CDC activities therein, and a mutant of an antagonistic anti-CD40 antibody, comprising at least one mutation or substitution in the constant region to reduce the ADCC and/or CDC activities therein, both mutants having at least a hinge region derived from a human IgG2.

摘要翻译： 提供潜在治疗性抗CD40抗体的突变体，其突变体具有降低的ADCC和CDC活性，被设计为作为药剂优化。 激动性抗CD40抗体的突变体，其包含恒定区中至少一个氨基酸的突变和/或取代以降低其中的ADCC和/或CDC活性，以及​​拮抗性抗-CD40抗体的突变体，其包含 在恒定区域中至少一个突变或取代以减少其中的ADCC和/或CDC活性，两个突变体具有至少一个衍生自人IgG2的铰链区。

公开(公告)号：US07193064B2

公开(公告)日：2007-03-20

申请号：US10693629

申请日：2003-10-23

申请人： Toshifumi Mikayama ,  Hitoshi Yoshida ,  Walker R. Force ,  Xingjie Chen ,  Nobuaki Takahashi

发明人： Toshifumi Mikayama ,  Hitoshi Yoshida ,  Walker R. Force ,  Xingjie Chen ,  Nobuaki Takahashi

IPC分类号： C07K16/28 ,  A61K39/395 ,  C12N5/12 ,  C12N15/13

CPC分类号： C07K16/2878 ,  A61K2039/505 ,  C07K2317/21 ,  C07K2319/00 ,  C07K2319/30

摘要： An antibody or a functional fragment thereof, acting agonistically or antagonistically on CD40.

公开(公告)号：US06422452B1

公开(公告)日：2002-07-23

申请号：US09768837

申请日：2001-01-25

申请人： Takumi Yamamoto ,  Kazuhiko Futakami ,  Akira Hatase ,  Nobuaki Takahashi ,  Naoji Senba ,  Yuzo Shimada

发明人： Takumi Yamamoto ,  Kazuhiko Futakami ,  Akira Hatase ,  Nobuaki Takahashi ,  Naoji Senba ,  Yuzo Shimada

IPC分类号： B23K100

摘要： An apparatus for lining up micro-balls in accordance with the present invention includes: ball carrying pallets having a plurality of pits for holding the micro-balls, respectively, on its surface, a pallet holder for holding the ball carrying pallets, a lining-up container defining a sealed chamber in association with the pallet holder hermetically fitted thereto, a storing tank for storing liquid carrier in which micro-balls are dispersed, and applying/collecting device for communicating the storing tank with the lining-up container via a passage to supply the micro-balls together with the liquid carrier from the storing tank to the sealed chamber and return the surplus micro-balls together with the liquid carrier from the sealed chamber to the storing tank.

公开(公告)号：US06264580B1

公开(公告)日：2001-07-24

申请号：US09630431

申请日：2000-08-01

申请人： Atsushi Tabata ,  Masato Kaigawa ,  Nobuaki Takahashi

发明人： Atsushi Tabata ,  Masato Kaigawa ,  Nobuaki Takahashi

IPC分类号： F16H6104

CPC分类号： F16H63/502 ,  B60W10/04 ,  B60W10/10 ,  B60W30/19 ,  B60W2510/0638 ,  B60W2540/16 ,  B60W2710/021 ,  F16H61/061 ,  F16H2061/0087 ,  Y10T477/693762

摘要： A control system for an automatic transmission, which is capable of controlling the hydraulic pressures for frictional engagement units when a predetermined shift is performed such that a first frictional engagement unit is engaged and a second frictional engagement unit is released, being connected to a power source, the revolving speed of which is temporarily raised when a predetermined shift down is performed, the control unit for the automatic transmission for a vehicle being structured such that shift which is performed by engaging and releasing the two frictional engagement units is judged, whether the judged shift is shift down in which the revolving speed of the power source is temporarily raised or shift down in which the revolving speed of the power source is not raised is judged, and the contents of control of the hydraulic pressures for the frictional engagement units are changed between shift down in which the revolving speed of the power source is temporarily raised and shift down in which the revolving speed of the power source is not raised.

摘要翻译： 一种用于自动变速器的控制系统，其能够在执行预定换挡时控制摩擦接合单元的液压，使得第一摩擦接合单元接合并且第二摩擦接合单元被释放，连接到电源 当执行预定的换档时，其转速暂时升高，用于车辆的自动变速器的控制单元被构造成使得通过接合和释放两个摩擦接合单元执行的换档被判断 判断电源的转速暂时升高或者电源的转速没有上升的向下偏移，并且摩擦接合单元的液压控制的内容变化 在电源的旋转速度暂时升高之间的下降之间 电源的转速没有上升。