公开(公告)号：US09795142B2

公开(公告)日：2017-10-24

申请号：US15195341

申请日：2016-06-28

申请人： Wizard Labs, LLC

发明人： Wiley William Hitchcock ,  James Michael Puckett

IPC分类号： A61K33/38 ,  A01N59/14 ,  A01N59/16 ,  A01N25/04

CPC分类号： A01N59/16 ,  A01N25/04 ,  A01N59/14 ,  A01N2300/00 ,  A61K33/38 ,  A61K2300/00

摘要： An odor eliminating solution comprises the active deodorizing and antimicrobial agents of silver nanoparticles dispersed in colloidal suspension in a solution containing excess sodium tetraborate decahydrate, commonly referred to as borax. The silver nanoparticles provide deodorizing and antimicrobial properties through the colloidal dispersion which provides a high surface area to volume ratio for the suspension. The sodium tetraborate decahydrate provides deodorizing and antimicrobial properties through its co-complexing ability with various substances. The combination of both provides the present invention with long term stability and deodorizing and antimicrobial activity. Furthermore, the present invention includes the method for formulating the odor eliminating solution through the combination of a silver nanoparticle source solution and an aqueous sodium tetraborate solution which results in a chemical reaction that synthesizes the silver nanoparticles from the silver cations. The resulting odor eliminating solution can be utilized independently or combined with existing odor management products.

公开(公告)号：US09776025B2

公开(公告)日：2017-10-03

申请号：US15016692

申请日：2016-02-05

申请人： Al Santelli, Jr.

发明人： Al Santelli, Jr.

IPC分类号： A62B23/06 ,  A61K9/00 ,  A61L9/16 ,  A61K33/38 ,  A61L2/00 ,  A61L2/238 ,  A61L9/00 ,  A61F5/08

CPC分类号： A62B23/06 ,  A61F5/08 ,  A61K9/0043 ,  A61K33/38 ,  A61L2/0082 ,  A61L2/238 ,  A61L9/00 ,  A61L9/16

摘要： A nasal insert including an antimicrobial agent is inserted into the nose to eliminate or reduce undesirable microbes in the area just inside the nose. Pads of the nasal insert can be formed from a blended polymer compound with a microbial agent. Processing of the pre-polymer results in the microbial agent being trapped in the polymer. A blowing agent or CO2 gas can be introduced in the process after decompression, and before molding to improve attraction of liquid born microbes to the nasal insert.

公开(公告)号：US20170246041A1

公开(公告)日：2017-08-31

申请号：US15590935

申请日：2017-05-09

申请人： Michelle Cumming ,  Mitchell Kastros ,  Marc Etchells ,  Paul E Lentz, III

发明人： Michelle Cumming ,  Mitchell Kastros ,  Marc Etchells ,  Paul E Lentz, III

IPC分类号： A61F13/12 ,  A61B5/145 ,  A61B5/00 ,  A61B17/132 ,  A61L15/58 ,  A61F13/00 ,  A61L15/26 ,  A61L15/60 ,  A61L15/44 ,  A61K33/38 ,  A61B5/01 ,  A61F7/02

CPC分类号： A61F13/12 ,  A61B5/0022 ,  A61B5/01 ,  A61B5/14542 ,  A61B17/1325 ,  A61F7/02 ,  A61F13/00017 ,  A61F13/00029 ,  A61F13/00038 ,  A61F13/00042 ,  A61F13/00046 ,  A61F13/00055 ,  A61F13/00059 ,  A61F13/00063 ,  A61F13/00987 ,  A61F13/0286 ,  A61F2007/0002 ,  A61F2007/0203 ,  A61F2007/0228 ,  A61F2007/0231 ,  A61F2013/00106 ,  A61K33/38 ,  A61L15/26 ,  A61L15/44 ,  A61L15/58 ,  A61L15/60 ,  A61L2300/404

摘要： An emergency hemostatic head trauma bandage cap with a strap system and method of use, which, when applied to the head, delivers minimal pressure to control bleeding, doesn't compromise cervical spine immobilization, allows for fast and effective application of cooling gel to control intracranial/internal swelling or hot packs to prevent hypothermia in non-trauma situations, doesn't come apart during treatment and transport, and doesn't require a caregiver to re-wrap the dressing.

公开(公告)号：US20170239208A1

公开(公告)日：2017-08-24

申请号：US15590767

申请日：2017-05-09

申请人： University of Johannesburg

发明人： Reinout Meijboom ,  Marianne Jacqueline Cronje

IPC分类号： A61K31/28 ,  A61K31/095 ,  A61K49/00 ,  C07F9/54 ,  A61K31/66 ,  A61K33/38

CPC分类号： A61K31/28 ,  A61K31/095 ,  A61K31/66 ,  A61K33/38 ,  A61K49/0004 ,  C07F9/5442

摘要： The present invention relates to the use of silver(I) monophosphine complexes as Active Pharmaceutical Ingredients (API's), including anticancer agents, for the treatment, diagnosis and/or prevention of cancer. The present invention also relates to pharmaceutical compositions containing such complexes and further extends to a method of treating or diagnosing a subject/patient suffering from cancer.

公开(公告)号：US20170202880A1

公开(公告)日：2017-07-20

申请号：US15475114

申请日：2017-03-30

申请人： KING SAUD UNIVERSITY

发明人： EBTESAM MOHAMMED AL OLAYAN ,  MANAL AHMED GASMELSEED AWAD ,  MUZZAMMIL IQBAL SIDDIQUI ,  NADA MOHAMMED MERGHANI

IPC分类号： A61K33/38 ,  B22F1/00 ,  B22F9/24 ,  A61K9/00 ,  A61K9/14

CPC分类号： A61K33/38 ,  A61K9/0014 ,  A61K9/148 ,  A61K36/328 ,  B22F1/0018 ,  B22F9/24 ,  B22F2009/245 ,  B22F2301/255 ,  B22F2304/054 ,  B22F2998/10 ,  Y02A50/409

摘要： The method for preparing metal nanoparticles includes preparing an extract of myrrh and mixing the extract with an aqueous solution including a metal salt. The mixture changes in color from light yellow to dark brown upon formation of nanoparticles. The extract of myrrh can be a water extract prepared by, for example, soaking a quantity of myrrh in water, filtering the soaked myrrh to obtain a filtered product, and then centrifuging the filtered product. The metal salt can be, for example, silver nitrate (AgNO3). The metal nanoparticles can be spherical, spheroidal, elongated spherical, rod, and/or faceted. The metal nanoparticles can be used to treat Leishmaniasis (lesions) caused by Leishmania major.

公开(公告)号：US09686997B2

公开(公告)日：2017-06-27

申请号：US14342455

申请日：2012-09-06

申请人： Luiz Gustavo Pagotto Simões ,  Andre Luiz De Araújo ,  Daniel Tamassia Minozzi

发明人： Luiz Gustavo Pagotto Simões ,  Andre Luiz De Araújo ,  Daniel Tamassia Minozzi

IPC分类号： A01N59/16 ,  A61K33/38 ,  A61K33/30 ,  A61K33/08 ,  A61K33/24 ,  A61K33/34

CPC分类号： A01N59/16 ,  A61K33/08 ,  A61K33/24 ,  A61K33/30 ,  A61K33/34 ,  A61K33/38 ,  A61K2300/00

摘要： The invention is generally directed to antimicrobial composition comprising a matrix material and both of silver and zinc distributed there through, wherein the matrix material comprises at least one of Si02, Ti02, Zr02, AI203, or Zeolite, and the uses of such compositions as antibacterial and acaricidal. The invention is also generally directed to antimicrobial composition comprising a matrix material arid both of silver and a metal selected from the group of noble or transition metals distributed there through, wherein the matrix material comprises at least one of Si02, Ti02, Zr02, AI203, or Zeolite, and the uses of such compositions as antibacterial and acaricidal.

公开(公告)号：US20170173213A1

公开(公告)日：2017-06-22

申请号：US15124401

申请日：2015-03-10

申请人： University of Rochester

发明人： Matthew YATES ,  Keith SAVINO ,  Paul GABRYS ,  Cong FU

IPC分类号： A61L27/32 ,  A61L31/08 ,  A61K33/42 ,  C25D9/04 ,  A61L31/16 ,  A61K33/38 ,  C25D3/46 ,  A61L27/30 ,  A61L27/54

CPC分类号： A61L27/32 ,  A61K33/38 ,  A61K33/42 ,  A61L27/30 ,  A61L27/306 ,  A61L27/54 ,  A61L31/086 ,  A61L31/088 ,  A61L31/16 ,  A61L2300/404 ,  A61L2400/12 ,  A61L2400/18 ,  A61L2420/02 ,  A61L2430/02 ,  C25D3/46 ,  C25D9/04

摘要： Polarized hydroxyapatite films disposed on a substrate. The films have a residual polarization of at least 5 mC/cm2. Also provided are methods of making and using polarized hydroxyapatite. The films can be used as coatings of medical devices, such as, for example, medical implants.

公开(公告)号：US09682172B2

公开(公告)日：2017-06-20

申请号：US14821019

申请日：2015-08-07

申请人： Warsaw Orthopedic, Inc.

发明人： Susan J. Drapeau ,  Guobao Wei

IPC分类号： A61F2/28 ,  A61F2/02 ,  A61K35/32 ,  A61L27/14 ,  A61L27/36 ,  A61L27/56 ,  A61K31/722 ,  A61K33/38 ,  A61K38/39 ,  A61L27/54 ,  A61K38/18 ,  A61L27/58

CPC分类号： A61L27/365 ,  A61K31/722 ,  A61K33/38 ,  A61K35/32 ,  A61K38/18 ,  A61K38/39 ,  A61L27/14 ,  A61L27/3608 ,  A61L27/54 ,  A61L27/56 ,  A61L27/58 ,  A61L2300/404 ,  A61L2300/406 ,  A61L2300/41 ,  A61L2300/414 ,  A61L2300/418 ,  A61L2400/04 ,  A61L2430/02 ,  A61K2300/00

摘要： A covering for delivering a therapeutic agent to a surgical site is provided. The covering may include a single or multi-compartment structure configured to at least partially retain the therapeutic agent until the covering is placed at a surgical site. Upon placement, the covering may facilitate transfer of the therapeutic agent to the surgical site. In some embodiments, the covering comprises an antimicrobial agent, a hemostatic agent, an anti-inflammatory agent, and/or a growth factor.

公开(公告)号：US09655924B2

公开(公告)日：2017-05-23

申请号：US14681701

申请日：2015-04-08

申请人： BioMedtrix, LLC

发明人： Christopher G. Sidebotham ,  Alan Mundell

IPC分类号： A61K33/38 ,  A61K31/60 ,  A61K45/06 ,  A61K36/752 ,  A61K31/56 ,  A61K9/00

CPC分类号： A61K33/38 ,  A61K9/0046 ,  A61K31/56 ,  A61K31/60 ,  A61K36/752 ,  A61K45/06 ,  A61K2300/00

摘要： Disclosed herein are compositions for treatment of ear infection (such as bacterial and/or yeast infection) in human or veterinary subjects. In some embodiments the compositions include silver microparticles, for example about 0.1% silver microparticles, about 0.2% silver microparticles, or about 0.4% silver microparticles. Also disclosed are methods for treating ear infection in a subject utilizing one or more of the disclosed compositions, for example sequential application of compositions including about 0.1% silver microparticles, about 0.2% silver microparticles, and about 0.4% silver microparticles to the ear canal of the subject. In some examples, one or more of the disclosed compositions are provided in a kit.

公开(公告)号：US09655923B2

公开(公告)日：2017-05-23

申请号：US14800997

申请日：2015-07-16

申请人： GNT Biotech & Medicals Corporation

发明人： Ying-Chen Yang ,  Chia-Nan Chen ,  Li-Ling Chi

IPC分类号： B82Y5/00 ,  A61K33/24 ,  A61K9/00 ,  B22F1/00 ,  A61K9/14 ,  A61K45/06 ,  A61K33/06 ,  A61K33/34 ,  A61K33/38

CPC分类号： A61K33/24 ,  A61K9/0019 ,  A61K9/14 ,  A61K33/06 ,  A61K33/34 ,  A61K33/38 ,  A61K45/06 ,  B22F1/00 ,  B82Y5/00 ,  C01P2004/64 ,  A61K2300/00

摘要： The invention relates to a method of using metal nanoparticle or metallic particle to promote neurite outgrowth and treat and/or prevent neurological disorders. Particularly, the method of the invention uses gold nanoparticles or gold particles to promote neurite outgrowth and treat and/or prevent neurological disorders.