Abstract:
Provided is an imaging system which includes an optical fiber array probe unit integrated with an endoscope unit, thereby simultaneously measuring structural information and functional information of a sample. The optical fiber array probe unit includes an optical fiber array probe integrated with lenses including an optical fiber lens with a lens surface of a predetermined radius of curvature in which one ends of optical fibers are integrally connected with each other by heating a predetermined region including the one ends of two of the optical fibers using a heating means, as an optical fiber array probe integrated lens on which the light transmitted from the light source is incident and which guides light reflected from the sample, and a detector for selectively detecting the light transmitted from the optical fiber array probe integrated with lenses in a predetermined range of wavelength.
Abstract:
The present invention relates to an image sensor comprising a microlens array, and to a manufacturing method thereof. The method of the present invention includes gradually increasing the aluminum composition ratio of a compound semiconductor as the latter gradually gets farther from a substrate, to enable a microlens-forming layer to grow, and making the oxidation rate of the region adjacent to the substrate slower and the oxidation rate of the region farther from the substrate faster, making the interface between the oxidized region and the unoxidized region into a lens shape after the completion of oxidation. The thus-made lens is integrated into an image sensor. The present invention reduces costs for manufacturing image sensors in which a microlens is integrated, increases the signal-to-noise ratio and resolution of the image sensor, and achieves improved sensitivity.
Abstract:
Iron oxide nano contrast agents for Magnetic Resonance Imaging which have superior T2 contrast effect, and also can be used as a storage or a carrier for drugs and so on, are disclosed. The iron oxide nano contrast agents can be prepared by the steps of: coating surfaces of hydrophobic FeO nanoparticles with a coating material selected from the group consisting of polyethylene glycol-phospholipid conjugate, dextran, chitosan, dimercaptosuccinic acid and mixtures thereof in an organic solvent to form hydrophilic FeO nanoparticles having hydrophilic surfaces and dispersibility in water; dispersing the hydrophilic FeO nanoparticles in water to oxidize FeO; and exposing the oxidized hydrophilic FeO nanoparticles to an acidic buffer to dissolve and remove interior unoxidized FeO portions, and thereby to form Fe3O4 nanoparticles having an interior space.
Abstract:
Provided is an imaging system which includes an optical fiber array probe unit integrated with an endoscope unit, thereby simultaneously measuring structural information and functional information of a sample. The optical fiber array probe unit includes an optical fiber array probe integrated with lenses including an optical fiber lens with a lens surface of a predetermined radius of curvature in which one ends of optical fibers are integrally connected with each other by heating a predetermined region including the one ends of two of the optical fibers using a heating means, as an optical fiber array probe integrated lens on which the light transmitted from the light source is incident and which guides light reflected from the sample, and a detector for selectively detecting the light transmitted from the optical fiber array probe integrated with lenses in a predetermined range of wavelength.
Abstract:
Disclosed are a helium gas liquefier and a method for liquefying a helium gas. The disclosed helium gas liquefier includes: a first cooling part including a first cooling column; a first cold head installed on the first cooling column, and a first cylinder in which the first cooling column and the first cold head are built; a second cooling part including a second cooling column, a second cold head installed on the second cooling column, and a second cylinder in which the second cooling column and the second cold head are built; and a liquid helium storage disposed under the second cooling part.
Abstract:
The present invention relates to a biomarker for diagnosis of overactive bladder (OAB) disease, and a method for screening a drug using the biomarker. The markers described in the present invention can effectively detect or diagnose the onset of OAB by distinguishing them from normal populations. In particular, OAB-specific protein markers released into urine enable simple and rapid OAB diagnosis in a non-invasive manner. In addition, by selecting an agent that changes, particularly normalizes the expression and activity of the markers selected in the present invention, more effective preventative or therapeutic agents of OAB disease can be screened.
Abstract:
A spiral phase plate, according to one embodiment, for generating a Laguerre Gaussian beam by reflecting an incident beam emitted from a light source, may comprise: a first quadrant area in which the step height increase rate per unit angle decreases progressively in one direction from the point with the lowest step height to the point with the highest step height; and a second quadrant area in which the step height increase rate per unit angle increases progressively in the one direction.
Abstract:
The disclosure relates a to manufacturing method of an all-solid-state lithium secondary battery including a solid polymer electrolyte, including preparing an all-solid-state lithium secondary battery by interposing a polymer electrolyte between a cathode and an anode; hardening the polymer electrolyte by applying a pressure and heat to the all-solid-state lithium secondary battery; activating the all-solid-state lithium secondary battery by applying a current; and removing a gas generated in the activated all-solid-state lithium secondary battery. By hardening a polymer electrolyte interposed between a cathode and an anode through applying a pressure and heat, a bubble or dead area inside solid polymer electrolyte is minimized with providing an electrode having uniform thickness. By repeating activation operation and removing gas, bonding of electrode stack is more enhanced, and stability of a battery is improved.
Abstract:
Provided are an anode active material for secondary battery which includes porous iron oxide nanoparticles, a manufacturing method thereof, and a secondary battery including the same. The anode active material for secondary battery of the present disclosure minimizes a volume change of iron oxide caused by intercalation and deintercalation of lithium even during consecutive charges and discharges and thus can improve the capacity and lifespan characteristics of a secondary battery employing the anode active material. Further, the manufacturing method of an anode active material for secondary battery makes it possible to manufacture an anode active material for secondary battery including iron oxide nanoparticles in an environmentally friendly and simple manner and thus makes it possible to mass-produce the anode active material.
Abstract:
The present invention relates to a composition comprising a CYP4A-inhibiting compound as an active ingredient for preventing or treating metabolic diseases, more specifically to a composition comprising the compound expressed by chemical formula 1 of the present invention or pharmaceutically acceptable salt thereof as an active ingredient for preventing, ameliorating or treating metabolic diseases.