公开(公告)号：US11208342B2

公开(公告)日：2021-12-28

申请号：US16173184

申请日：2018-10-29

Applicant: University of Florida Research Foundation, Inc.

Inventor： Mark E. Orazem ,  Arthur R. Dizon

IPC: C02F11/12 ,  C02F11/00 ,  B01D21/00 ,  C02F11/123 ,  C02F11/15 ,  C02F101/10 ,  C02F103/04 ,  C02F103/12 ,  C02F103/10

Abstract: Various examples related to electrokinetic dewatering (EKD) of suspensions such as, e.g., phosphatic clay suspensions are provided. In one example, a system for continuous EKD includes cake dewatering unit having a lower conveying belt extending across a dewatering chamber; an upper conveying belt extending across at least a portion of the dewatering chamber; and a sludge inlet configured to supply a sludge suspension on the first end of the lower conveying belt. The conveying belts can extend across the dewatering chamber at an angle. Rotation of the conveying belts draws the sludge suspension through an electric field where the sludge suspension is dewatered. The electric field can be established between an upper anode and a lower cathode. The upper and lower conveying belts can include the anode and cathode. A suspension thickening unit can provide a thickened sludge suspension the cake dewatering unit for enhanced dewatering.

公开(公告)号：US11207841B2

公开(公告)日：2021-12-28

申请号：US16334202

申请日：2017-09-18

Applicant: University of Florida Research Foundation, Inc.

Inventor： Yong Huang ,  Yifei Jin ,  Ashley M. Compaan ,  Wenxuan Chai ,  Chengcheng Liu

IPC: B29C64/40 ,  B29C64/106 ,  B29C64/20 ,  B33Y10/00 ,  B33Y30/00 ,  B33Y70/00 ,  B29C64/112 ,  B29C64/00 ,  B29K105/00

Abstract: Embodiments of the present disclosure provide for systems and methods of three dimensional printing including a precursor build material comprising a hydrogel precursor and a support material, wherein the precursor build material has a gel-like state when a stress applied to the precursor build material is less than a yield stress, wherein the precursor build material has a free-flow state when the stress applied to the precursor build material is above the yield stress, wherein when the stress applied to the precursor build material changes from above the yield stress to below the yield stress, the precursor build material returns to the gel-like state.

公开(公告)号：US11207663B2

公开(公告)日：2021-12-28

申请号：US16467088

申请日：2017-12-06

Applicant: University of Florida Research Foundation, Inc.

Inventor： George Christou ,  Kylie J. Mitchell

IPC: C01F17/30 ,  C01F17/235 ,  B01J23/10

Abstract: Described herein are compositions and methods relating to molecular cerium-oxide nanoclusters. In an aspect, described herein are methods of synthesizing molecular cerium-oxide nanocluster compositions and compositions thereof. In an aspect, described herein are methods of scavenging reactive oxygen species utilizing molecular cerium-oxide nanoclusters as described herein. Also described herein are pharmaceutical compositions and methods of use. Pharmaceutical compositions as described herein can comprise a therapeutically effective amount of a compound (such as a composition comprising one or more molecular cerium-oxide nanoclusters), or a pharmaceutically acceptable salt of the compound, and a pharmaceutically acceptable carrier. Methods of treating oxidative stress are also described herein, comprising administering pharmaceutical compositions as described herein to a subject in need thereof. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

公开(公告)号：US11197946B2

公开(公告)日：2021-12-14

申请号：US16347725

申请日：2017-11-07

Applicant: University of Florida Research Foundation, Inc.

Inventor： Wallace Gregory Sawyer ,  Thomas Ettor Angelini ,  Steven C. Ghivizzani ,  C. Parker Gibbs

IPC: A61L27/38 ,  A61F2/28

Abstract: Described herein are methods and apparatus for constructing tissue replacements, such as bone replacements that may be used to repair damaged or missing segments of bone, such as may occur in wound repair or as a repair of a congenital anomaly. These methods involve a three-dimensional (3D) cell growth medium made from a yield stress material that allows cells and structures to be easily deposited and positioned.

公开(公告)号：US11193925B2

公开(公告)日：2021-12-07

申请号：US16384122

申请日：2019-04-15

Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. ,  XHALE, INC.

Inventor： Donn Dennis ,  Matthew Booth ,  Scott Wasdo ,  Chris Batich ,  Hank Wohltjen ,  Douglas Crumb ,  Mark Tanner ,  Susan Baumgartner ,  Poonam Kaul

IPC: G01N33/497 ,  G01N30/74 ,  A61B5/00 ,  A61B5/083 ,  A61B5/097 ,  A61B5/08 ,  A61B5/087 ,  A61B10/00 ,  G01N30/02

Abstract: A Self Monitoring And Reporting Therapeutics, SMART® composition, method apparatus and system are provided which flexibly provide options, by combining different embodiments of the device with different embodiments of the composition, the ability to conduct definitive medication adherence monitoring over the short term (Acute Medication Adherence Monitoring, immediately up to an hour or so after taking a medication), intermediate term (Intermediate Medication Adherence Monitoring, IMAM, an hour or so to a day or so after taking a medication), and longer term (Chronic Medication Adherence Monitoring, CMAM, a day to several days after taking a medication).

公开(公告)号：US11179721B2

公开(公告)日：2021-11-23

申请号：US15746319

申请日：2016-07-21

Applicant: University of Florida Research Foundation, Inc.

Inventor： Jason E. Butler ,  Anthony J. Ladd ,  Mert Arca

IPC: G01N27/447 ,  B01L3/00 ,  G01N1/40 ,  C12Q1/6816 ,  C12Q1/6806

Abstract: Provided herein are microfluidic devices that can be configured to generate an electrophoretic flow that is in opposition to a fluid flow through a microcapillary of a microfluidic device provided herein. Also provided herein are methods that include adding an amount of particle to the inlet area of a microfluidic device as provided herein, generating a first fluid flow through a microcapillary of a microfluidic device provided herein; and applying a uniform electric field to the microfluidic device, where the uniform electric field generates an electrophoretic flow that is in opposition to the fluid flow.

公开(公告)号：US11177766B2

公开(公告)日：2021-11-16

申请号：US15069373

申请日：2016-03-14

Applicant: University of Florida Research Foundation, Inc.

Inventor： Jiangeng Xue ,  Wei David Wei

IPC: H02S40/22 ,  H02S20/26 ,  B32B27/18 ,  B32B27/36 ,  B32B27/20 ,  B32B17/00 ,  B32B3/08 ,  B32B27/30 ,  B32B27/06 ,  B32B7/04 ,  B32B27/40

Abstract: A photovoltaic system is formed as a window that is constructed of at least one polymer layer that is filled or decorated with metal nanoparticles and a window frame that includes one or more photovoltaic cells. The metal nanoparticles have a shape and size such that they display surface plasmon resonance frequencies in the near-infrared and/or the near-ultraviolet. The near-infrared and/or the near-ultraviolet radiations are scattered such that they are transmitted parallel to the face of the window to the photovoltaic cells, where an electrical current is generated.

公开(公告)号：US11160859B2

公开(公告)日：2021-11-02

申请号：US16382429

申请日：2019-04-12

Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. ,  CORNELL RESEARCH FOUNDATION, INC. ,  The Government of The United States of America as represented by The Secretary of The Department of Health and Human Services. Centers for Disease Control and Prevention

Inventor： Patti Cynthia Crawford ,  Paul J. Gibbs ,  Edward J. Dubovi ,  Ruben Omar Donis ,  Jacqueline Katz ,  Alexander I. Klimov ,  Nallakannu P. Lakshmanan ,  Melissa Anne Lum ,  Daniel Ghislena Emiel Goovaerts ,  Mark William Mellencamp ,  Nancy J. Cox ,  William L. Castleman

IPC: A61K39/145 ,  A61K39/12 ,  C07K14/005 ,  C12N7/00 ,  C07K16/10 ,  C12Q1/70 ,  G01N33/569 ,  C12N15/86 ,  A61K39/00

Abstract: The subject invention pertains to isolated influenza virus that is capable of infecting canids and causing respiratory disease in the canid. The subject invention also pertains to compositions and methods for inducing an immune response against an influenza virus of the present invention. The subject invention also pertains to compositions and methods for identifying a virus of the invention and diagnosing infection of an animal with a virus of the invention.

公开(公告)号：US20210322301A1

公开(公告)日：2021-10-21

申请号：US17124910

申请日：2020-12-17

Applicant: Abfero Pharmaceuticals, Inc. ,  University of Florida Research Foundation, Inc.

Inventor： Steven Keith BURKE ,  Raymond J. BERGERON

IPC: A61K9/00 ,  A61K31/357 ,  A61K31/075 ,  A61K31/426 ,  A61K47/54 ,  A61K31/4196 ,  A61K31/05 ,  A61K31/192 ,  A61K31/132 ,  A61K31/047 ,  A61K31/16 ,  A61K31/4412

Abstract: The present disclosure provides safe and effective dosing regimens of metal chelators as treatment for metal overload disorders and, in particular, iron overload and associated conditions.

公开(公告)号：US20210284540A1

公开(公告)日：2021-09-16

申请号：US17258191

申请日：2019-07-18

Applicant: University of Florida Research Foundation, Inc.

Inventor： Jonathan SCHEFFE ,  Kent J. WARREN

IPC: C01B32/50 ,  C01B5/00 ,  C01F17/32 ,  B01J19/32 ,  B01J19/24

Abstract: The present disclosure provide for methods of reforming a hydrocarbon such as methane. In an aspect, when the method is driven via renewable energy (e.g., use of solar energy, wind energy, or other renewable energy) and coupled with zero-energy input product gas separation, this enables the capture of pure CO2 (i.e., carbon sequestration) and carbon-neutral utilization of methane can be achieved. As a result, the present disclosure can provide for a method to reform methane with zero-energy input product gas separation.