公开(公告)号：US20110112281A1

公开(公告)日：2011-05-12

申请号：US12993684

申请日：2009-05-19

申请人： Takashi Yamashita

发明人： Takashi Yamashita

IPC分类号： C07K16/02 ,  C07K16/30

CPC分类号： C07K16/241 ,  A01K67/0275 ,  A01K2217/052 ,  A01K2227/30 ,  A01K2267/01 ,  C07K16/2806 ,  C07K2317/11 ,  C07K2317/21 ,  C07K2317/72 ,  C07K2317/734 ,  C12N15/8509 ,  C12N2799/027

摘要： The present invention relates to a cytotoxic composition that contains, as an active ingredient, an IgG antibody produced in eggs of a transgenic avian with a gene encoding the IgG antibody. The IgG antibody is expected to produce high anti-tumor effects with less side-effects because this antibody has higher CDC activity than that of the corresponding CHO cell-derived IgG antibody and its primary protein structure is not altered. The present invention also provides an agent for ameliorating or treating a cancer and an agent for treating an autoimmune disease, which contain the cytotoxic composition.

摘要翻译： 本发明涉及含有编码IgG抗体的基因的转基因禽类卵中产生的IgG抗体作为活性成分的细胞毒性组合物。 预期IgG抗体产生较高的抗肿瘤作用，具有较少的副作用，因为该抗体具有比相应的CHO细胞来源的IgG抗体更高的CDC活性，并且其初级蛋白质结构不被改变。 本发明还提供了用于改善或治疗癌症的药剂和用于治疗包含细胞毒性组合物的自身免疫疾病的药剂。

公开(公告)号：US07882083B2

公开(公告)日：2011-02-01

申请号：US11985101

申请日：2007-11-14

申请人： Masahiro Kataoka ,  Takashi Yamashita ,  Kenji Furuichi ,  Takashi Tsubokura

发明人： Masahiro Kataoka ,  Takashi Yamashita ,  Kenji Furuichi ,  Takashi Tsubokura

IPC分类号： G06F17/30

CPC分类号： G06F17/30979

摘要： An information retrieval apparatus includes contents, an index data generating unit, a character frequency management data generating unit, a compressing/encrypting unit, a retrieval initializing unit, a full text retrieving unit, and a retrieval result displaying unit. The character frequency management data generating unit generates character frequency management data based on the contents. The compressing/encrypting unit compresses the contents and encrypts the character frequency management data. The retrieval initializing unit decrypts encrypted character frequency management data. The full text retrieving unit executes full text retrieval for compressed contents using the character frequency management data and index data when receiving a retrieval keyword. The retrieval result displaying unit decompresses a retrieval candidate selected from retrieval candidates and displays as a retrieval result.

摘要翻译： 信息检索装置包括内容，索引数据生成单元，字符频率管理数据生成单元，压缩/加密单元，检索初始化单元，全文检索单元和检索结果显示单元。 字符频率管理数据生成部基于内容生成字符频率管理数据。 压缩/加密单元压缩内容并加密字符频率管理数据。 检索初始化单元解密加密的字符频率管理数据。 全文检索单元在收到检索关键词时，使用字符频率管理数据和索引数据执行压缩内容的全文检索。 检索结果显示单元将从检索候选和显示中选择的检索候选解压缩作为检索结果。

公开(公告)号：US07869233B2

公开(公告)日：2011-01-11

申请号：US10553756

申请日：2004-07-12

申请人： Masaki Okamura ,  Takashi Yamashita

发明人： Masaki Okamura ,  Takashi Yamashita

IPC分类号： H02M1/14

CPC分类号： H02M5/4585

摘要： A control device calculates a voltage command value of a voltage step-up converter based on a torque command value and a motor revolution number and calculates an on-duty of an NPN transistor based on the calculated voltage command value and a DC voltage from a voltage sensor. When the on-duty is influenced by a dead time of NPN transistors, control device fixes the on-duty at 1.0 to control the NPN transistors in such a manner that the voltage is increased or decreased.

摘要翻译： 控制装置基于转矩指令值和电动机转数来计算升压转换器的电压指令值，并根据计算出的电压指令值和来自电压的直流电压计算NPN晶体管的占空比 传感器。 当占空比受NPN晶体管的死区时间影响时，控制装置将占空比固定为1.0，以使电压升高或降低的方式控制NPN晶体管。

公开(公告)号：US20100148686A1

公开(公告)日：2010-06-17

申请号：US12636242

申请日：2009-12-11

申请人： Tomoyoshi Arimoto ,  Takashi Yamashita ,  Tetsuji Hirao ,  Tetsu Okamoto ,  Kentaro Fujita

发明人： Tomoyoshi Arimoto ,  Takashi Yamashita ,  Tetsuji Hirao ,  Tetsu Okamoto ,  Kentaro Fujita

IPC分类号： H05B41/36

CPC分类号： H05B41/2928 ,  H05B41/2883 ,  H05B41/3928 ,  Y02B20/202 ,  Y02B20/208

摘要： A discharge lamp lighting apparatus includes a discharge container, a pair of electrodes and a power supply apparatus. An alternating current of a frequency, which is lower than stationary frequency, is inserted periodically into the alternating current of stationary frequency. When a lighting current value of the discharge lamp is smaller than a predetermined lower limit, the frequency is set as predetermined minimum frequency. When the lighting current value of a discharge lamp is larger than a predetermined maximum value, the frequency is set as predetermined maximum frequency. When a lighting current value of the discharge lamp is between the lower limit and the maximum value, the frequency is set as a selected frequency corresponding to the lighting current value. The selected frequency increases according to an increase of frequency change as a lighting current value increases.

摘要翻译： 放电灯点灯装置包括放电容器，一对电极和电源装置。 频率低于固定频率的交流电周期性地插入到固定频率的交流电中。 当放电灯的点亮电流值小于预定的下限时，将频率设定为预定的最小频率。 当放电灯的点亮电流值大于预定的最大值时，将频率设定为预定的最大频率。 当放电灯的点亮电流值在下限和最大值之间时，频率被设定为与点亮电流值对应的选定频率。 所选择的频率随着照明电流值增加而随着频率变化的增加而增加。

公开(公告)号：US20090148641A1

公开(公告)日：2009-06-11

申请号：US11909881

申请日：2006-03-30

申请人： Koichi Uchida ,  Takashi Yamashita

发明人： Koichi Uchida ,  Takashi Yamashita

IPC分类号： B32B27/34 ,  B32B1/08

CPC分类号： B32B27/34 ,  B32B1/08 ,  C08G69/26 ,  C08G69/265 ,  C08L23/0815 ,  C08L77/06 ,  C08L77/10 ,  Y10T428/1393 ,  Y10T428/31732 ,  C08L2666/20 ,  C08L23/00

摘要： Provision of a multilayer structure superior in the alcohol gasoline permeation-preventing property, interlayer adhesiveness, low temperature impact resistance, heat resistance and chemical resistance. A multilayer structure comprising at least two layers of layer A consisting of a polyamide resin composition (a) comprising 30-90 mass % of a polyamide resin (X) comprising a dicarboxylic acid unit comprising 50-100 mol % of a terephthalic acid unit and/or a lo naphthalene dicarboxylic acid unit, and a diamine unit comprising 60-100 mol % of an aliphatic diamine unit having 9-13 carbon atoms, and 70-10 mass % of an impact resistance modifier, and layer B consisting of a polyamide resin composition (b) comprising 50-95 mass % of a polyamide resin (X′) comprising a dicarboxylic acid unit comprising 50-100 mol % of a terephthalic acid unit and/or a naphthalene dicarboxylic acid unit, and a diamine unit comprising 60-100 mol % of an aliphatic diamine unit having 9-13 carbon atoms, and 50-5 mass % of an impact resistance modifier, which satisfies Y≧Y′+5 wherein Y shows a content ratio (mass %) of the impact resistance modifier in layer A and Y′ shows a content ratio (mass %) of the impact resistance modifier in layer B.

摘要翻译： 提供优异的醇汽油渗透防止性，层间粘合性，低温耐冲击性，耐热性和耐化学性的多层结构。 一种多层结构，包括至少两层由聚酰胺树脂组合物（a）构成的层A，所述层包含30-90质量％的包含50-100摩尔％的对苯二甲酸单元的二羧酸单元的聚酰胺树脂（X）和 /或者萘二羧酸单元，以及含有碳原子数为9〜13的脂肪族二胺单元60〜100摩尔％，耐冲击性改性剂70〜10质量％的二胺单元，以及由聚酰胺 包含50-95质量％的包含包含50-100摩尔％的对苯二甲酸单元和/或萘二羧酸单元的二羧酸单元的聚酰胺树脂（X'）的树脂组合物（b）和包含60 -100摩尔％的具有9-13个碳原子的脂族二胺单元和50-5质量％的耐冲击性改性剂，其满足Y> = Y'+ 5，其中Y表示冲击的含量比（质量％） 层A和Y'中的电阻改性剂表示冲击的含量比（质量％） 层B中的电阻改性剂

公开(公告)号：US20090098325A1

公开(公告)日：2009-04-16

申请号：US11908974

申请日：2006-03-17

申请人： Koichi Uchida ,  Hirofumi Kikuchi ,  Tsugunori Kashimura ,  Takashi Yamashita ,  Hiroki Yamasaki

发明人： Koichi Uchida ,  Hirofumi Kikuchi ,  Tsugunori Kashimura ,  Takashi Yamashita ,  Hiroki Yamasaki

IPC分类号： F16L11/04 ,  C08G69/26 ,  F16L37/00 ,  B32B27/08 ,  C08L77/06

CPC分类号： B32B1/08 ,  B32B27/34 ,  C08G69/26 ,  C08K7/02 ,  C08L77/06 ,  Y10T428/1393

摘要： A semi-aromatic polyamide resin is provided which has a high level of residence stability, hot-water resistance and chemical resistance and is also excellent in adhesive properties and compatibility with other resins and the like.The semi-aromatic polyamide resin comprises: dicarboxylic acid units in which 50 to 100 mol % of the dicarboxylic acid units are aromatic dicarboxylic acid units; and diamine units in which 60 to 100 mol % of the diamine units are aliphatic diamine units having 9 to 13 carbon atoms. Furthermore, at least 10% of terminal groups of molecular chains of the polyamide resin are blocked with a terminal-blocking agent, and the amount of terminal amino groups of the molecular chains is 60 μeq/g or more and 120 μeq/g or less. In addition, [NH2]/[COOH]≧6 is satisfied, where [NH2] (μeq/g) represents the amount of the terminal amino groups and [COOH] (μeq/g) represents the amount of terminal carboxyl groups.

摘要翻译： 提供了具有高水平的保持稳定性，耐热水性和耐化学性的半芳族聚酰胺树脂，并且粘合性能和与其它树脂等的相容性也优异。 半芳香族聚酰胺树脂包括：二羧酸单元，其中50-100mol％的二羧酸单元是芳族二羧酸单元; 和二胺单元为60〜100摩尔％的二胺单元为碳原子数为9〜13的脂肪族二胺单元。 此外，聚酰胺树脂的分子链的末端基团的至少10％用封端剂封端，分子链的末端氨基的量为60mueq / g以上且120mueq / g以下 。 另外，[NH 2] / [COOH] = 6，其中[NH 2]（mueq / g）表示末端氨基的量，[COOH]（mueq / g）表示末端羧基的量。

公开(公告)号：US20070165432A1

公开(公告)日：2007-07-19

申请号：US10553756

申请日：2004-07-12

申请人： Masaki Okamura ,  Takashi Yamashita

发明人： Masaki Okamura ,  Takashi Yamashita

IPC分类号： H02M7/5387

CPC分类号： H02M5/4585

摘要： A control device calculates a voltage command value of a voltage step-up converter based on a torque command value and a motor revolution number and calculates an on-duty of an NPN transistor based on the calculated voltage command value and a DC voltage from a voltage sensor. When the on-duty is influenced by a dead time of NPN transistors, control device fixes the on-duty at 1.0 to control the NPN transistors in such a manner that the voltage is increased or decreased.

摘要翻译： 控制装置基于转矩指令值和电动机转数来计算升压转换器的电压指令值，并根据计算出的电压指令值和来自电压的直流电压计算NPN晶体管的占空比 传感器。 当占空比受NPN晶体管的死区时间影响时，控制装置将占空比固定为1.0，以使电压升高或降低的方式控制NPN晶体管。

公开(公告)号：US06794392B1

公开(公告)日：2004-09-21

申请号：US09417216

申请日：1999-10-13

申请人： Tsuneji Suzuki ,  Tomoyuki Ando ,  Katsutoshi Tsuchiya ,  Osamu Nakanishi ,  Akiko Saito ,  Takashi Yamashita ,  Yoshinori Shiraishi ,  Eishi Tanaka

发明人： Tsuneji Suzuki ,  Tomoyuki Ando ,  Katsutoshi Tsuchiya ,  Osamu Nakanishi ,  Akiko Saito ,  Takashi Yamashita ,  Yoshinori Shiraishi ,  Eishi Tanaka

IPC分类号： A61K31505

CPC分类号： C07D213/30 ,  C07C233/80 ,  C07C237/42 ,  C07C255/57 ,  C07C271/20 ,  C07C275/24 ,  C07C275/40 ,  C07C335/16 ,  C07C335/20 ,  C07D207/34 ,  C07D211/22 ,  C07D213/38 ,  C07D213/40 ,  C07D213/50 ,  C07D213/56 ,  C07D213/61 ,  C07D213/64 ,  C07D213/65 ,  C07D213/74 ,  C07D213/75 ,  C07D213/81 ,  C07D213/82 ,  C07D215/48 ,  C07D215/54 ,  C07D231/12 ,  C07D233/56 ,  C07D233/64 ,  C07D233/90 ,  C07D241/12 ,  C07D241/24 ,  C07D249/08 ,  C07D261/08 ,  C07D261/18 ,  C07D263/24 ,  C07D275/03 ,  C07D277/24 ,  C07D277/40 ,  C07D295/088 ,  C07D307/12 ,  C07D307/68 ,  C07D333/16 ,  C07D333/70 ,  C07D401/06 ,  C07D405/12 ,  C07D413/12 ,  C07D453/02 ,  C07D491/04

摘要： The novel benzamide derivative represented by formula (1) and the novel anilide derivative represented by formula (13) of this invention has differentiation-inducing effect, and are, therefore, useful a therapeutic or improving agent for malignant tumors, autoimmune diseases, dermatologic diseases and parasitism. In particular, they are highly effective as an anticancer drug, specifically to a hematologic malignancy and a solid carcinoma.

摘要翻译： 由式（1）表示的新型苯甲酰胺衍生物和本发明式（13）表示的新型酰苯胺衍生物具有诱导分化作用，因此可用于恶性肿瘤，自身免疫疾病，皮肤病的治疗或改善剂 和寄生。 特别是作为抗癌药物，特别是血液恶性肿瘤和实体癌是非常有效的。

公开(公告)号：US06783171B2

公开(公告)日：2004-08-31

申请号：US10180731

申请日：2002-06-27

申请人： Minoru Teishi ,  Takashi Yamashita ,  Takashi Ogawa

发明人： Minoru Teishi ,  Takashi Yamashita ,  Takashi Ogawa

IPC分类号： B60J1008

CPC分类号： B60J10/24 ,  B60J10/21 ,  B60J10/80

摘要： When a sealing portion at an end portion of an extruded weatherstrip is cut out by a fixed length and a main body and a lip are set on a metal mold for die forming, concave portions are formed on a lower surface and side surface of the main body to be set on the metal mold, and are latched, respectively with convex portions of the metal mold to restrict movement. Thus a problem in external appearance caused by movement or bending of a part of the main body including the lip due to a molding pressure is eliminated.

摘要翻译： 当将挤压密封条的端部的密封部分切割成固定长度，将主体和唇缘设置在用于模具成型的金属模具上时，在主体的下表面和侧表面上形成凹部 主体被设置在金属模具上，分别与金属模具的凸起部分锁定以限制运动。 因此，消除了由于成型压力而由包括唇缘的主体的一部分的运动或弯曲引起的外观的问题。

公开(公告)号：US06677682B1

公开(公告)日：2004-01-13

申请号：US09620555

申请日：2000-07-20

申请人： Noriaki Fujiki ,  Shigeru Harada ,  Takashi Yamashita

发明人： Noriaki Fujiki ,  Shigeru Harada ,  Takashi Yamashita

IPC分类号： H01L23544

CPC分类号： H01L23/544 ,  H01L21/76819 ,  H01L2223/54426 ,  H01L2223/54453 ,  H01L2924/0002 ,  H01L2924/00

摘要： An interlayer insulating film (21) is formed on a substrate (1), and a polysilicon layer (10) is formed on the interlayer insulating film (21). An interlayer insulating film (22) is formed to cover the polysilicon layer (10), and a polysilicon layer (11) is formed on the interlayer insulating film (22). An interlayer insulating film (23) is formed to cover the interlayer insulating film (22). A hole (20M) for a mark to constitute an alignment mark or the like is formed from a surface (23S) of the interlayer insulating film (23) to the polysilicon layer (11). The hole (20M) for a mark is larger than a contact hole formed from the surface (23S) to the substrate (1) but is shallower than the contact hole. Consequently, a concave portion corresponding to the hole (20M) for a mark is formed, with difficulty, on a silicon oxide layer to be subjected to CMP polishing and then become an interlayer insulting film (4). Therefore, it is possible to prevent a slurry from remaining in the concave portion. Thus, it is possible to obtain a semiconductor device having high reliability without a disadvantage such as a wiring disconnection or the like which is caused by the remaining or scattering of the slurry to be used for a CMP method.

摘要翻译： 在基板（1）上形成层间绝缘膜（21），在层间绝缘膜（21）上形成多晶硅层（10）。 形成层间绝缘膜（22）以覆盖多晶硅层（10），并且在层间绝缘膜（22）上形成多晶硅层（11）。 形成层间绝缘膜（23）以覆盖层间绝缘膜（22）。 从层间绝缘膜（23）到多晶硅层（11）的表面（23S）形成用于构成对准标记等的标记的孔（20M）。 用于标记的孔（20M）大于从表面（23S）到基板（1）形成的接触孔，但是比接触孔浅。 因此，难以在氧化硅层上形成与用于标记的孔（20M）对应的凹部，进行CMP研磨后，成为层间绝缘膜（4）。 因此，可以防止浆料残留在凹部中。 因此，可以获得具有高可靠性的半导体器件，而没有由用于CMP方法的浆料的剩余或散射引起的诸如布线断开等的缺点。