METHOD AND SYSTEM FOR PREDICTING ADVERSE DRUG-DRUG INTERACTIONS BY RECOVERING THE MULTI-ATTRIBUTE INFORMATION OF DRUGS, AND MEDIUM

    公开(公告)号:US20240170104A1

    公开(公告)日:2024-05-23

    申请号:US18325572

    申请日:2023-05-30

    CPC classification number: G16C20/30 G16C20/70

    Abstract: The present invention discloses the method and system for predicting adverse drug-drug interactions by recovering the multi-attribute information of drugs and the medium. The method includes: collecting adverse drug-drug interactions data and multi-attribute data of drugs; constructing the recovery model of multi-attribute absent feature of drugs; correcting the recovery model of multi-attribute absent feature of drugs by the cosine similarity regularization term, and solving the corrected recovery model to obtain the common features and unique features of multi-attribute information of drugs; obtaining the multi-attribute information of two drugs, calculating common features and unique features of their multi-attribute information as the inputs of the prediction model to predict their adverse drug-drug interactions. The present invention improves the accuracy of the prediction of the adverse drug-drug interactions, promotes the experimental study of the adverse drug-drug interactions, and ensures the safety of medication.

    Blockchain-based time stamping method for digital signature

    公开(公告)号:US11936799B2

    公开(公告)日:2024-03-19

    申请号:US17032041

    申请日:2020-09-25

    CPC classification number: H04L9/3297 H04L9/3236 H04L9/3247 H04L9/50

    Abstract: A method for blockchain-based time stamping for digital signature is disclosed. The method includes two participants: a signer who signs a message, a verifier who verifies the message. In the method, the signer obtains hash values of a certain number of latest confirmed blocks in blockchain, binds these hash values and the message together to be a new message. The signer then generates a signature of the new message and inserts identification data of this signature and the new message into a transaction of blockchain. This method ensures that the generation time of the signature is prior to the generation time of the block which contains the signature and, at the same time, is after the generation time of the blocks whose hash values are included in the signature, which produces an accurate time interval for the digital signature.

    RANDOM PHASE MODULATION METHOD DEPENDING ON COMMUNICATION DISTANCE

    公开(公告)号:US20230421284A1

    公开(公告)日:2023-12-28

    申请号:US18033375

    申请日:2021-04-29

    CPC classification number: H04K1/006

    Abstract: A random phase modulation method depending on a communication distance is provided. In the method, time synchronization is carried out by means of a transmitter and a receiver, a local random signal is generated, and an original signal to be sent is pre-coded according to a transmission delay and the generated local random signal, such that random phase modulation depending on a communication distance is realized, potential security brought about by positions of the transmitter and the receiver is fully utilized, a receiver at an expected distance position can receive a signal with a correct phase, and a receiver at another distance position receives a signal with a scrambled phase, thereby improving the secure communication capability of a wireless communication system in terms of the dimension of space.

    METHOD FOR ROBOT ASSISTED MULTI-VIEW 3D SCANNING MEASUREMENT BASED ON PATH PLANNING

    公开(公告)号:US20230339112A1

    公开(公告)日:2023-10-26

    申请号:US18140784

    申请日:2023-04-28

    CPC classification number: B25J9/1664 B25J9/1671 B25J9/1692 B25J19/021

    Abstract: Robot assisted multi-view 3D scanning measurement based on path planning includes firstly, establishing a virtual simulation platform to complete the setting of measurement poses and measurement paths and perform the path evaluations of measurement paths. Then, completing the preliminary hand-eye calibration based on the properties of Kronecker product, and the preliminary hand-eye calibration is optimized by establishing a reprojection error cost function as the fitness function of the particle swarm optimization algorithm. Lastly, moving the robot to the measurement poses of the planned measurement paths, obtaining a single-view point cloud of the measured object and transforming it from the camera coordinate system to the robot base coordinate system to obtain a registered single-view point cloud based on the optimized hand-eye matrix. When registered single-view point clouds of all measurement poses are obtained, the points under the robot base coordinate system form a complete point cloud of the measured object.

    POWER AMPLIFIER
    118.
    发明公开
    POWER AMPLIFIER 审中-公开

    公开(公告)号:US20230327611A1

    公开(公告)日:2023-10-12

    申请号:US17875465

    申请日:2022-07-28

    CPC classification number: H03F1/42 H03F3/245 H03F1/32 H03F2200/36 H03F2200/451

    Abstract: An ultra-wideband power amplifier includes a preamplifier circuit and a post amplifier circuit. The preamplifier circuit includes a first DC blocking capacitor C1, a first decoupling capacitor C2, a second decoupling capacitor C3, a stabilizing resistor Rin, a first AC blocking resistor RG1, a first input inductor L1, a second input inductor L2, an output inductor L3, a first input microstrip line MLIN1, a second input microstrip line MLIN2, an output microstrip line MLIN3, and a first transistor Q1. A first end of the first DC blocking capacitor C1 acts as an input terminal of the preamplifier circuit, and a second end of the first DC blocking capacitor C1 is connected to the stabilizing resistor Rin, the first input inductor L1, the first input microstrip line MLIN1, and a gate electrode of the first transistor Q1 sequentially. One end of the first decoupling capacitor C2 is grounded.

    MULTI-LEVEL GATE DRIVER APPLIED TO SIC MOSFET
    119.
    发明公开

    公开(公告)号:US20230326973A1

    公开(公告)日:2023-10-12

    申请号:US17848422

    申请日:2022-06-24

    Abstract: A multi-level gate driver applied to the SiC metal-oxide-semiconductor field-effect transistor (MOSFET) includes three parts: the SiC MOSFET information detection circuit, the signal level shifting circuit, and the segmented driving circuit. The SiC MOSFET information detection circuit includes the SiC MOSFET drain-source voltage detection circuit and the SiC MOSFET drain-source current detection circuit. The segmented driving circuit includes a turn-on segmented driving circuit and a turn-off segmented driving circuit. The SiC MOSFET drain-source voltage detection circuit and the SiC MOSFET drain-source current detection circuit process a drain-source voltage and a drain-source current during the SiC MOSFET's switching as enable signals for segmented driving; the signal level shifting circuit transfers enable signals required by the segmented driving circuit to the suitable power supply rail; and the SiC MOSFET turn-on segmented driving circuit and the turn-off segmented driving circuit select suitable driving currents.

    Fish-like underwater robot
    120.
    发明授权

    公开(公告)号:US11685490B2

    公开(公告)日:2023-06-27

    申请号:US17326348

    申请日:2021-05-21

    CPC classification number: B63G8/001 B63H1/36 B63H23/02 B63G2008/002

    Abstract: A fish-like underwater robot includes a shell, a driving assembly and an integrated tension and swing component. The integrated tension and swing component includes a plurality of tension ropes and tension elements. Every two adjacent tension elements are connected in series through the plurality of tension ropes. The driving assembly and the integrated tension and swing component are disposed inside the shell. The driving assembly is disposed at a head of the shell. The integrated tension and swing component has an end connected to a tail of the shell and an end connected to the driving assembly. When the fish-like underwater robot is used, the driving assembly drives the integrated tension and swing component to swing to generate power for forward movement. A traditional fish-like tail swing structure is replaced with an integrated tension skeleton structure.

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