公开(公告)号：US20100074853A1

公开(公告)日：2010-03-25

申请号：US12624980

申请日：2009-11-24

申请人： David Gan ,  Michelle Hines ,  Javier Aravena ,  Brian Jones

发明人： David Gan ,  Michelle Hines ,  Javier Aravena ,  Brian Jones

IPC分类号： A61K8/97 ,  A61K8/27 ,  A61Q19/00 ,  A61Q17/04

CPC分类号： A61K36/889 ,  A61K8/97 ,  A61K9/0014 ,  A61K9/06 ,  A61K9/107 ,  A61K36/185 ,  A61K45/06 ,  A61K2800/522 ,  A61Q19/02 ,  A61Q19/08 ,  A61K2300/00

摘要： A topical skin care composition comprising kakadu plum extract or acai berry extract, or a combination of both, is disclosed. The composition can include a high oxygen radical absorbance capacity (ORAC) value. The composition can improve the skin's visual appearance, physiological functions, clinical properties, and/or biophysical properties.

摘要翻译： 公开了包含卡卡杜李提取物或阿卡酸浆果提取物或两者的组合的局部皮肤护理组合物。 组合物可以包括高氧自由基吸收容量（ORAC）值。 该组合物可以改善皮肤的视觉外观，生理功能，临床特性和/或生物物理性质。

公开(公告)号：US07657896B2

公开(公告)日：2010-02-02

申请号：US11019095

申请日：2004-12-21

申请人： Shawn Alan Villaron ,  Brian Jones ,  Chad Rothschiller

发明人： Shawn Alan Villaron ,  Brian Jones ,  Chad Rothschiller

IPC分类号： G06F3/00 ,  G06F9/44 ,  G06F9/46 ,  G06F13/00

摘要： Methods and systems are provided for exposing nested data in computer-generated documents in a transparent manner. A mechanism is provided for a client application to query a server application for a list of available file formats after an object is requested from a server application document for embedding into a client application document. Another mechanism is provided for the client application to request a particular format associated with the embedded object from the server application document. Once the client application obtains file format information available to the server application or associated with the particular object, the client application may utilize the obtained file formats for utilizing or operating on the embedded object according to the native file formats associated with the embedded object.

公开(公告)号：US07451156B2

公开(公告)日：2008-11-11

申请号：US11275724

申请日：2006-01-25

申请人： David Ornstein ,  Andrey Shur ,  Mike Hillberg ,  Brian Jones ,  Daniel Emerson ,  Jerry Dunietz ,  Oliver Foehr ,  Bruce MacKenzie ,  Jean Paoli ,  Josh Pollock ,  Sarjana Sheth

发明人： David Ornstein ,  Andrey Shur ,  Mike Hillberg ,  Brian Jones ,  Daniel Emerson ,  Jerry Dunietz ,  Oliver Foehr ,  Bruce MacKenzie ,  Jean Paoli ,  Josh Pollock ,  Sarjana Sheth

IPC分类号： G06F17/30

CPC分类号： G06F17/211 ,  G06F17/2229 ,  G06F17/2247 ,  Y10S707/99942 ,  Y10S707/99943 ,  Y10S707/99945 ,  Y10S707/99953

摘要： Modular content framework and document format methods and systems are described. The described framework and format define a set of building blocks for composing, packaging, distributing, and rendering document-centered content. These building blocks define a platform-independent framework for document formats that enable software and hardware systems to generate, exchange, and display documents reliably and consistently. The framework and format have been designed in a flexible and extensible fashion. In addition to this general framework and format, a particular format, known as the reach package format, is defined using the general framework. The reach package format is a format for storing paginated documents. The contents of a reach package can be displayed or printed with full fidelity among devices and applications in a wide range of environments and across a wide range of scenarios.

公开(公告)号：US07416113B2

公开(公告)日：2008-08-26

申请号：US11891742

申请日：2007-08-13

申请人： Thomas A. VanKirk ,  Jon E. Washington ,  Brian Jones ,  William D. Beskitt ,  Harry Thomas Graef ,  David A. Peters ,  Damon J. Blackford ,  Dale H. Blackson ,  Edward L. Laskowski ,  Songtao Ma ,  Tim Crews ,  Kenneth Turocy ,  Douglas T. Dominick ,  Jason J. Smolk ,  Brian E. Lucas ,  Bradley Lightner

发明人： Thomas A. VanKirk ,  Jon E. Washington ,  Brian Jones ,  William D. Beskitt ,  Harry Thomas Graef ,  David A. Peters ,  Damon J. Blackford ,  Dale H. Blackson ,  Edward L. Laskowski ,  Songtao Ma ,  Tim Crews ,  Kenneth Turocy ,  Douglas T. Dominick ,  Jason J. Smolk ,  Brian E. Lucas ,  Bradley Lightner

IPC分类号： G07F19/00

CPC分类号： G07F19/202 ,  G06Q20/042 ,  G07D11/0087 ,  G07F19/20 ,  G07F19/203

摘要： An automated banking machine that is activated responsive to data read from user cards which accepts checks and dispense cash to users. The automatic banking machine is operated to acquire image and magnetic data from deposited checks to determine the genuineness of checks and the authority of a user to receive cash for such checks. Cash may be dispensed to the user from the automatic banking machine in exchange for a deposited check. The automatic banking machine dispenses cash responsive to communications with a transaction host.

摘要翻译： 一种自动银行机器，响应于从用户卡读取的数据被激活，该用户卡接受对用户的检查和分配现金。 操作自动银行机器从存入的支票中获得图像和磁数据，以确定支票的真实性和用户接收这种支票的现金的权限。 可以从自动银行机器向用户分配现金，以换取支票。 自动银行机器响应于与交易主机的通信而分配现金。

公开(公告)号：US20080063774A1

公开(公告)日：2008-03-13

申请号：US11809104

申请日：2007-05-31

申请人： Wolfgang Aehle ,  David Estell ,  Ronaldus Hommes ,  Brian Jones ,  Marc Kolkman ,  Chris Leeflang ,  Hiroshi Oh ,  Ayrookaran Poulose ,  Andrew Shaw ,  Wilhelmus Van Der Kley ,  Leonardus Van Marrewijk

发明人： Wolfgang Aehle ,  David Estell ,  Ronaldus Hommes ,  Brian Jones ,  Marc Kolkman ,  Chris Leeflang ,  Hiroshi Oh ,  Ayrookaran Poulose ,  Andrew Shaw ,  Wilhelmus Van Der Kley ,  Leonardus Van Marrewijk

IPC分类号： A23K1/00 ,  C07H21/00 ,  C11D7/42 ,  C12N1/00 ,  C12N1/15 ,  C12N1/21 ,  C12N15/63 ,  C12N9/50 ,  D06M16/00

CPC分类号： C12N9/52 ,  A23K20/189 ,  A23K50/75 ,  C11D3/386 ,  C12N9/96 ,  C12Y304/21 ,  D06M16/003

摘要： The present invention provides novel Micrococcineae spp serine proteases having multiple substitutions. In particular, the present invention provides serine proteases having multiple substitutions, DNA encoding these proteases, vectors comprising the DNA encoding the proteases, host cells transformed with the vector DNA, and enzymes produced by the host cells. The present invention also provides cleaning compositions (e.g., detergent compositions), animal feed compositions, and textile and leather processing compositions comprising these serine protease variants. In particularly preferred embodiments, the present invention provides mutant (i.e., variant) proteases derived from the wild-type proteases described herein. These variant proteases also find use in numerous applications.

摘要翻译： 本发明提供了具有多个取代的新型微球菌spp丝氨酸蛋白酶。 特别地，本发明提供了具有多个取代的丝氨酸蛋白酶，编码这些蛋白酶的DNA，包含编码蛋白酶的DNA的载体，用载体DNA转化的宿主细胞和由宿主细胞产生的酶。 本发明还提供了清洁组合物（例如洗涤剂组合物），动物饲料组合物以及包含这些丝氨酸蛋白酶变体的纺织和皮革加工组合物。 在特别优选的实施方案中，本发明提供衍生自本文所述的野生型蛋白酶的突变体（即，变体）蛋白酶。 这些变体蛋白酶也可用于许多应用。

公开(公告)号：US20080023539A1

公开(公告)日：2008-01-31

申请号：US11881044

申请日：2007-07-25

申请人： Aarthi Rao ,  Dale Chapman ,  Eric Toepke ,  Kristen Stewart ,  Keith Carpenter ,  Thomas A. VanKirk ,  Jon E. Washington ,  Brian Jones ,  William D. Beskitt ,  Harry Thomas Graef ,  David A. Peters ,  Damon J. Blackford ,  Dale H. Blackson ,  Songtao Ma ,  Tim Crews ,  Kenneth Turocy ,  Douglas T. Dominick ,  Jasen J. Smolk ,  Brian E. Lucas ,  Bradley Lightner

发明人： Aarthi Rao ,  Dale Chapman ,  Eric Toepke ,  Kristen Stewart ,  Keith Carpenter ,  Thomas A. VanKirk ,  Jon E. Washington ,  Brian Jones ,  William D. Beskitt ,  Harry Thomas Graef ,  David A. Peters ,  Damon J. Blackford ,  Dale H. Blackson ,  Songtao Ma ,  Tim Crews ,  Kenneth Turocy ,  Douglas T. Dominick ,  Jasen J. Smolk ,  Brian E. Lucas ,  Bradley Lightner

IPC分类号： G07F19/00

CPC分类号： G07F19/207 ,  G06Q20/042 ,  G07F19/20

摘要： An automated banking-machine that is actuated responsive to data read from user cards, accepts checks and dispenses cash to users. The banking machine is operated to acquire image and magnetic data from deposited checks to determine the genuineness of checks and the authority of a user to receive cash for such checks. Cash may be dispensed to the user from the automated banking machine in exchange for a deposited check. The automated banking machine dispenses cash responsive to communications with a transaction host.

摘要翻译： 响应于从用户卡读取的数据而启动的自动银行机器接受对用户的检查和分配现金。 操作银行机器从存入的支票中获得图像和磁性数据，以确定支票的真实性和用户接收现金用于此类支票的权限。 可以从自动银行机器向用户分配现金，以换取存款支票。 自动银行机器响应于与交易主机的通信而分配现金。

公开(公告)号：US20070299506A1

公开(公告)日：2007-12-27

申请号：US11820094

申请日：2007-06-18

申请人： Matthew Carter ,  Brian Jones

发明人： Matthew Carter ,  Brian Jones

IPC分类号： A61F2/82 ,  A61F2/06

CPC分类号： A61F2/82 ,  A61B17/22 ,  A61B2017/320004 ,  A61B2017/320012

摘要： A stent is provided that is able to resist clogging from cumulative matter found within a fluid that passes therethrough. The stent includes a mass moveably disposed therein, wherein movement of the stent tends to dislodge any cumulative matter accumulated within the stent. As a result, the device is able to remain resident within the patient for an extended period of time before becoming clogged and needing to be replaced.

摘要翻译： 提供一种能够抵抗在通过其中的流体中发现的累积物质堵塞的支架。 支架包括可移动地设置在其中的质量块，其中支架的运动倾向于移除在支架内积累的任何累积物质。 因此，该设备能够在被阻塞并且需要更换之前长时间地保持在患者体内。

公开(公告)号：US20070292537A1

公开(公告)日：2007-12-20

申请号：US11789017

申请日：2007-04-23

申请人： Brian Jones ,  Michelle Hines

发明人： Brian Jones ,  Michelle Hines

IPC分类号： A61K36/00 ,  A61K36/424 ,  A61K36/746 ,  A61Q19/08

CPC分类号： A61Q19/08 ,  A61K8/63 ,  A61K8/64 ,  A61K8/97 ,  A61K2800/782

摘要： The present invention provides a cosmetic composition having a cosmetically acceptable vehicle and one or more gap junction inhibitors and/or one or more choline acetyl transferase (CAT) inhibitors in an amount effective for reducing the appearance of deep wrinkles on the skin. Also provided is a method of reducing the appearance of deep wrinkles on the skin, including the steps of topically applying to the skin the above cosmetic composition in an amount and for a period of time sufficient to reduce the appearance of deep wrinkles on the skin.

摘要翻译： 本发明提供了一种具有美容上可接受的载体和一种或多种间隙连接抑制剂和/或一种或多种胆碱乙酰转移酶（CAT）抑制剂的化妆品组合物，其量可以有效减少皮肤上的深层皱纹的出现。 还提供了减少皮肤上深层皱纹外观的方法，包括以下步骤：将上述化妆品组合物局部地施用至足以减少皮肤上皱纹外观的量和时间。

公开(公告)号：US20070278287A1

公开(公告)日：2007-12-06

申请号：US11891742

申请日：2007-08-13

申请人： Thomas Vankirk ,  Jon Washington ,  Brian Jones ,  William Beskitt ,  Harry Graef ,  David Peters ,  Damon Blackford ,  Dale Blackson ,  Edward Laskowski ,  Songtao Ma ,  Tim Crews ,  Kenneth Turocy ,  Douglas Dominick ,  Jasen Smolk ,  Brian Lucas ,  Bradley Lightner

发明人： Thomas Vankirk ,  Jon Washington ,  Brian Jones ,  William Beskitt ,  Harry Graef ,  David Peters ,  Damon Blackford ,  Dale Blackson ,  Edward Laskowski ,  Songtao Ma ,  Tim Crews ,  Kenneth Turocy ,  Douglas Dominick ,  Jasen Smolk ,  Brian Lucas ,  Bradley Lightner

IPC分类号： G07F19/00

CPC分类号： G07F19/202 ,  G06Q20/042 ,  G07D11/0087 ,  G07F19/20 ,  G07F19/203

摘要： An automated banking machine that is activated responsive to data read from user cards which accepts checks and dispense cash to users. The automatic banking machine is operated to acquire image and magnetic data from deposited checks to determine the genuineness of checks and the authority of a user to receive cash for such checks. Cash may be dispensed to the user from the automatic banking machine in exchange for a deposited check. The automatic banking machine dispenses cash responsive to communications with a transaction host.

摘要翻译： 一种自动银行机器，响应于从用户卡读取的数据被激活，该用户卡接受对用户的检查和分配现金。 操作自动银行机器从存入的支票中获得图像和磁数据，以确定支票的真实性和用户接收这种支票的现金的权限。 可以从自动银行机器向用户分配现金，以换取支票。 自动银行机器响应于与交易主机的通信而分配现金。

公开(公告)号：US07303752B2

公开(公告)日：2007-12-04

申请号：US10825692

申请日：2004-04-16

申请人： Peter Hotez ,  James Ashcom ,  Mahnaz Bdamchian ,  Bin Zhan ,  Yan Wang ,  John Hawdon ,  Alexander Loukas ,  Angela Williamson ,  Brian Jones ,  Jeffrey Bethony ,  Gaddam Goud ,  Maria Elena Bottazzi ,  Susana Mendez

发明人： Peter Hotez ,  James Ashcom ,  Mahnaz Bdamchian ,  Bin Zhan ,  Yan Wang ,  John Hawdon ,  Alexander Loukas ,  Angela Williamson ,  Brian Jones ,  Jeffrey Bethony ,  Gaddam Goud ,  Maria Elena Bottazzi ,  Susana Mendez

IPC分类号： A61K39/00 ,  A61K39/002

CPC分类号： A61K39/0003 ,  A61K2039/55577 ,  Y02A50/412 ,  Y02A50/466

摘要： Preparations which elicit an immune response to hookworm antigens and which may be utilized as hookworm vaccines are provided. In addition, a method of increasing the effectiveness of vaccinations against infectious diseases in patients infected with hookworm is provided. The method involves chemically treating the hookworm infestation prior to administering the vaccine.

摘要翻译： 提供了引起钩虫抗原免疫应答并可用作钩虫疫苗的制剂。 另外，提供了一种增加感染钩虫感染病毒感染性疾病疫苗接种有效性的方法。 该方法包括在施用疫苗之前化学处理钩虫感染。