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公开(公告)号：US20130243753A1
公开(公告)日：2013-09-19
申请号：US13708685
申请日：2012-12-07
Applicant: GENENTECH, INC.
Inventor： Lin Pei , Yan Wu , Xiaofen Ye
IPC: A61K45/06 , A61K39/395
CPC classification number: A61K45/06 , A61K39/39558 , A61K2039/505 , A61K2039/507 , C07K16/22 , C07K16/2863 , C07K2317/21 , C07K2317/31 , C07K2317/73 , C07K2317/76 , C07K2317/92 , A61K2300/00
Abstract: The invention provides anti-Axl antibodies and methods of using the same.
Abstract translation: 本发明提供抗Ax1抗体及其使用方法。
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公开(公告)号：US20240384000A1
公开(公告)日：2024-11-21
申请号：US18416031
申请日：2024-01-18
Applicant: Genentech, Inc.
Inventor： Yvonne Chinn , Julie Q. Hang , Christian W. Siebel , Yan Wu , Daniel Lafkas
IPC: C07K16/28 , A61K39/00 , A61K39/395 , A61K47/68
Abstract: The invention provides anti-Jagged1 antibodies and methods of using the same.
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公开(公告)号：US11926674B2
公开(公告)日：2024-03-12
申请号：US17085750
申请日：2020-10-30
Applicant: Genentech, Inc.
Inventor： Yvonne Chinn , Julie Q. Hang , Christian W. Siebel , Yan Wu , Daniel Lafkas
IPC: A61K39/00 , A61K39/395 , A61K47/68 , C07K16/28
CPC classification number: C07K16/2896 , A61K39/3955 , A61K47/6849 , C07K16/28 , A61K2039/505 , A61K2039/507 , C07K2317/21 , C07K2317/33 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92
Abstract: The invention provides anti-Jagged2 antibodies and methods of using the same.
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公开(公告)号：US20240076388A1
公开(公告)日：2024-03-07
申请号：US18194906
申请日：2023-04-03
Applicant: GENENTECH, INC.
Inventor： Junichiro Sonoda , Yan Wu
IPC: C07K16/28 , A61K39/395 , A61K45/06 , C07K16/40
CPC classification number: C07K16/2863 , A61K39/3955 , A61K45/06 , C07K16/28 , C07K16/40 , A61K2039/505
Abstract: The invention provides FGFR1 agonists, including agonistic anti-FGFR1 antibodies, and methods of using the same.
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公开(公告)号：US11919948B2
公开(公告)日：2024-03-05
申请号：US17205663
申请日：2021-03-18
Applicant: Genentech, Inc.
Inventor： Wei-Ching Liang , Joseph R. Arron , Daryle Depianto , Wendy Green Halpern , WeiYu Lin , Patrick J. Lupardus , Thirumalai Rajan Ramalingam , Dhaya Seshasayee , Tianhe Sun , Tulika Tyagi , Jia Wu , Yan Wu , Jian Ping Yin
IPC: C07K16/22 , A61K39/00 , A61K39/395 , A61P11/00 , C07K16/46
CPC classification number: C07K16/22 , A61P11/00 , C07K16/464 , A61K39/39533 , A61K39/39566 , A61K2039/505 , C07K2317/24 , C07K2317/31 , C07K2317/41 , C07K2317/565 , C07K2317/76 , C07K2317/92
Abstract: The invention provides isoform-selective anti-TGFβ antibodies and methods of using the same. In particular, isoform-selective anti-TGFβ2, anti-TGFβ3, and anti-TGFβ2/3 monoclonal antibodies are provided, e.g., for the treatment of fibrosis and other TGFβ-related disorders.
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Patent Agency Ranking
公开(公告)号：US20240026033A1
公开(公告)日：2024-01-25
申请号：US18194276
申请日：2023-03-31
Applicant: Genentech, Inc.
Inventor： Yongmei Chen , James Ernst , Hok Seon Kim , Junichiro Sonoda , Christoph Spiess , Scott Stawicki , Yan Wu
CPC classification number: C07K16/40 , C07K14/71 , C07K16/2863 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/75 , C07K2317/92 , C07K2317/40 , C07K2317/41 , C07K2317/524 , C07K2317/567 , C07K2317/71 , A61K2039/505
Abstract: The presently disclosed subject matter provides antibodies that bind KLB and FGFR1, and methods of using the same. In certain embodiments, an antibody of the present disclosure includes a bispecific antibody that binds to an epitope present on FGFR1 and binds to an epitope present on KLB.
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公开(公告)号：US20220064331A1
公开(公告)日：2022-03-03
申请号：US17341990
申请日：2021-06-08
Applicant: GENENTECH, INC.
Inventor： Yongmei Chen , James Ernst , Hok Seon Kim , Junichiro Sonoda , Christoph Spiess , Scott Stawicki , Yan Wu
Abstract: The presently disclosed subject matter provides antibodies that bind KLB and FGFR1, and methods of using the same. In certain embodiments, an antibody of the present disclosure includes a bispecific antibody that binds to an epitope present on FGFR1 and binds to an epitope present on KLB.
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公开(公告)号：US10882920B2
公开(公告)日：2021-01-05
申请号：US15525791
申请日：2015-11-18
Applicant: Genentech, Inc. , Adimab LLC
Inventor： Yichin Liu , Jasvinder Atwal , Cecilia Pui Chi Chiu , Ryan J. Watts , Yan Wu , Eric Krauland , Michael Feldhaus
IPC: C07K16/40 , A61K47/68 , A61K39/00 , G01N33/573
Abstract: The invention provides antagonistic antibodies to BACE1 and methods of using the same for the treatment of neurological disease and disorders.
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公开(公告)号：US10858440B2
公开(公告)日：2020-12-08
申请号：US15997299
申请日：2018-06-04
Applicant: Genentech, Inc.
Inventor： Yvonne Chinn , Julie Q. Hang , Christian W. Siebel , Yan Wu , Daniel Lafkas
IPC: A61K39/00 , C07K16/28 , A61K47/68 , A61K39/395
Abstract: The invention provides anti-Jagged1 antibodies and methods of using the same.
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公开(公告)号：US20200377610A1
公开(公告)日：2020-12-03
申请号：US16872631
申请日：2020-05-12
Applicant: Genentech, Inc.
Inventor： Christian W. Siebel , Yan Wu
Abstract: The invention provides anti-Jagged antibodies and methods of using the same.
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