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公开(公告)号：US20210139684A1
公开(公告)日：2021-05-13
申请号：US17043179
申请日：2019-03-29
Inventor： Warintorn Thitsartarn , Chaobin He , Chee Chuan Jayven Yeo , Nopphawan Phonthammachai , Supakitt Treethammakul , Tanapon Sukachonmakul
Abstract: A reinforced polyolefin composite is provided. The reinforced polyolefin composite comprises a polyolefin such as polyethylene or polypropylene, a rigid fibre micro filler such as glass fiber, carbon or cellulosic fibers, and at least one nano filler such as clay. The reinforced polyolefin composite may also comprise a modified polyolefin, which has a polar functional group such as maleate monoester, an acid anhydride or an acrylate grafted thereon. The clay nano filler may also be modified with an organosilane. The reinforced polyolefin composite may also comprise a stabilizer or other additives. A method of producing the reinforced polyolefin composite is also provided, comprising mixing a polyolefin, a rigid micro filler and at least one nano filler to form a mixture, melting the mixture and kneading the melted mixture. The obtained reinforced polyolefin composite is used in transportation, infrastructure, consumer goods and construction.
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公开(公告)号：US10995220B2
公开(公告)日：2021-05-04
申请号：US15558738
申请日：2016-03-16
Applicant: Agency for Science, Technology and Research
Inventor： Parthiban Anbanandam
IPC: C09D5/16 , A01N33/12 , C08G18/75 , C08G18/32 , C09D175/04 , C08G18/08 , A01N47/12 , C07C215/40 , C08G18/24 , C09D175/12 , C08G73/02
Abstract: Provision of hydroxyl group functionalized quaternary ammonium halides, photocurable or hydrolytically curable urethane based polymers thereof and their use as antifouling agents.
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公开(公告)号：US10993917B2
公开(公告)日：2021-05-04
申请号：US16343434
申请日：2017-12-29
Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
Inventor： Motoichi Kurisawa , Ki Hyun Bae , Susi Tan
IPC: A61K9/50 , A61P35/00 , A61K47/61 , A61K33/243 , A61K9/51 , A61K31/282 , A61K31/41 , A61K31/555 , A61K47/69 , A61K31/665
Abstract: There is provided a nanocomplex having a core-shell structure. The shell of the nanocomplex comprises a functionalized hyaluronic acid while the core of the nanocomplex comprises a flavonoid encapsulating a metal-containing compound. Preferably, the flavonoid is epigallocatechin gallate (EGCG) and the hyaluronic acid is thiol-functionalized and subsequently conjugated to the flavonoid. There is also provided a method of forming the nanocomplex, a pharmaceutical composition comprising the nanocomplex, medical uses of the nanocomplex and a method of treating a patient, preferably with cancer using the nanocomplex.
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公开(公告)号：US20210123021A1
公开(公告)日：2021-04-29
申请号：US16965197
申请日：2019-01-25
Applicant: Agency for Science, Technology and Research
Inventor： Lai Guan NG , Maximilien EVRARD , Immanuel Weng Han KWOK
IPC: C12N5/0787 , C07K14/705 , G01N33/50
Abstract: Disclosed is a method of characterising and/or separating neutrophils, the method comprises characterising and/or separating the neutrophils into a first population comprising proliferative neutrophils and a second population comprising mature neutrophils, according to the expression of CD101 on the neutrophils. Also disclosed are compositions comprising proliferative neutrophils that are CD10−CD101−, and methods of treatment, diagnostic or prognostic using neutrophils thereof, as well as kits for characterising and/or separating proliferative neutrophils based on the expression of CD101 or CD10. In a preferred embodiment, the population of neutrophils may be characterised as proliferative neutrophils if CD10−CD101−, as immature neutrophils if CD10−CD101+ and as mature neutrophils if CD10+CD101+.
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公开(公告)号：US20210119623A1
公开(公告)日：2021-04-22
申请号：US16971226
申请日：2019-03-11
Applicant: Agency for Science, Technology and Research
Inventor： Yoshio Nishida , Ravinder Pal Singh
Abstract: Various embodiments may provide a comparator circuit arrangement. The comparator circuit arrangement may include a preamplifier having a first input configured to be coupled to a first input voltage, a second input configured to be coupled to a second input voltage, and an output configured to generate a preamplifier output signal based on the first input voltage and the second input voltage. The comparator circuit arrangement may also include a switch circuit arrangement coupled to the preamplifier, the switch circuit arrangement configured to deactivate the preamplifier upon the second input voltage exceeding the first input voltage and further configured to activate the preamplifier upon a fall of the second input voltage, and a pull-up circuit arrangement coupled to the output of the preamplifier, the pull-up circuit arrangement configured to provide a boost voltage to the preamplifier output signal for a predetermined duration upon the fall of the second input voltage.
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Patent Agency Ranking
公开(公告)号：US20210111880A1
公开(公告)日：2021-04-15
申请号：US15999422
申请日：2017-02-15
Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
Inventor： Shuqin REN , Hong Meng Benjamin TAN , Khin Mi Mi AUNG
Abstract: An access control method, which may be applied in a cloud environment, is provided in various embodiments. The access control method includes: receiving from a user a request for access to a resource; determining a group access key related to the resource; determining a user key of the user; determining whether the group key is an integer multiple of the user key; and granting the user access to the resource if it is determined that the group access key is an integer multiple of the user key.
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公开(公告)号：US20210108050A1
公开(公告)日：2021-04-15
申请号：US16499028
申请日：2018-03-28
Applicant: Agency for Science, Technology and Research
Inventor： Warintron Thitsartarn , Chaobin He , Jayven Chee Chuan Yeo
Abstract: According to the present disclosure, a method of forming an exfoliated or intercalated filler material is provided, wherein the said method comprises the steps of mixing particles of filler material such as montmorillonite (MMT), mica, layered double hydroxide (LDH), and attapulgite (AT) dispersed in an aqueous medium with cationic acrylate monomers to form modified particles comprising positively charged ions, dispersing the modified particles in organic medium to form a dispersion, contacting said dispersion with an organo-silicate such as tetraethyl orthosilicate (TEOS) and a functionalizing agent comprising an organo-silane such as aminopropyltrimethoxysilane (APTMS), in the presence of a basic catalyst to form a layer of silica on the modified particles. The present disclosure also relates to an exfoliated or intercalated filler material obtained by the said method as well as a method of forming a resin/clay nanocomposite.
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公开(公告)号：US20210107231A1
公开(公告)日：2021-04-15
申请号：US16968318
申请日：2019-02-14
Inventor： Xiling Yao , Youxiang Chew , Guijun Bi , Seung Ki Moon
IPC: B29C64/393 , G06T17/20 , B33Y50/02
Abstract: There is provided a method of additive manufacturing using at least one processor, the method includes: determining a first slicing layer of a three-dimensional (3D) model of a 3D object; determining a second slicing layer of the 3D model based on the first slicing layer, the second slicing layer being immediately subsequent to the first slicing layer; and determining a thickness of the second slicing layer and an orientation for a third slicing layer of the 3D model based on a difference between the second slicing layer and the first slicing layer, the third slicing layer being immediately subsequent to the second slicing layer. There is also provided a corresponding system and computer program product for additive manufacturing.
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129.发明申请公开(公告)号：US20210106997A1
公开(公告)日：2021-04-15
申请号：US17077828
申请日：2020-10-22
Applicant: Agency for Science, Technology and Research
Inventor： Jackie Y. Ying , Min-Han Tan , Yoke San Daniel Lee , Igor Cima , Yeon Joon Park , Wai Min Phyo
IPC: B01L3/00 , C12N5/071 , G01N33/50 , G01N33/574 , C12Q1/6886
Abstract: A column-based device and method for retrieving cells of interest were enclosed. The said device comprises a column comprising (i) an inner wall defining an inner chamber with inlet and outlet openings, (ii) a perforated plug disposed adjacent to the outlet opening, (iii) a sleeve insert with a channel and disposed within the chamber and adjacent to the perforated plug, and (iv) a filtering means housed within sleeve insert sandwiched between two sealing means. In particular, Tumor-derived endothelial cell clusters (TECCs) as characterized multiple nuclei, expression of endothelial markers (PECAM1, VWF and CDH5), and non-expression of leukocyte, megakaryocyte and platelets markers, may be retrieved using the disclosed device. Also encompassed are methods, reagents and kits for the diagnosis and prognosis of cancers by detecting for the presence of TECCs isolated from blood samples using the claimed device.
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公开(公告)号：US20210091942A1
公开(公告)日：2021-03-25
申请号：US16499132
申请日：2018-03-28
Applicant: Agency for Science, Technology and Research
Inventor： Duy Hieu Nguyen , Sumei Sun , Yong Dong Wu , Boon Shyang Lim
Abstract: There is provided a method of generating a secret key at a first node for data communication between the first node and a second node. The method includes obtaining a channel estimate of a communication channel between the first and second nodes; obtaining a time-frequency matrix associated with the communication channel based on a time-frequency transformation of the channel estimate; and producing the secret key based on the time-frequency matrix. There is also provided a corresponding key generator for generating a secret key.
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