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195 条记录 (耗时 0.048 秒)

    Inorganic-organic melt-extruded hybrid filaments and medical applications thereof
    121.
    发明申请
    Inorganic-organic melt-extruded hybrid filaments and medical applications thereof 审中-公开
    无机 - 有机熔融挤出混合长丝及其医疗应用

    公开(公告)号：US20090004470A1

    公开(公告)日：2009-01-01

    申请号：US12217314

    申请日：2008-07-03

    申请人： Shalaby W. Shalaby

    发明人： Shalaby W. Shalaby

    IPC分类号： D01F8/00 ,  A61B6/00

    CPC分类号： D01F1/10 ,  A61L17/10 ,  A61L31/128 ,  A61L31/18 ,  Y10T428/249938 ,  Y10T428/2913 ,  Y10T428/2927 ,  Y10T428/298

    摘要： Inorganic-organic hybrid, melt-extruded filaments having variable cross-sectional geometry with a cross-sectional area ranging between 100μ2 and 4 mm2 include an inorganic component that comprises at least 10 weight percent of the total system and is present as dispersed micro-/nanoparticles in an organic absorbable or non-absorbable matrix representing no more than 90 weight percent. Hybrid filaments are particularly useful for the production of absorbable/disintegratable coil components of an absorbable/disintegratable endoureteral stent and radiopaque surgical markers or sutures.

    摘要翻译： 无机 - 有机杂化物，具有横截面积在100m 2和4mm 2之间的截面几何形状的熔体挤出长丝包括无机组分，其包含总体系的至少10重量％，并以分散的微孔/ 表示不超过90重量％的有机可吸收或不可吸收的基质中的纳米颗粒。 混合细丝特别可用于生产可吸收/可分解的输尿​​管支架和不透射线外科标记物或缝合线的可吸收/可分解的线圈组件。

    High strength fibers of l-lactide copolymers, ε-caprolactone, and trimethylene carbonate and absorbable medical constructs thereof
    123.
    发明授权
    High strength fibers of l-lactide copolymers, ε-caprolactone, and trimethylene carbonate and absorbable medical constructs thereof 有权
    1-丙交酯共聚物，ε-己内酯和三亚甲基碳酸酯的高强度纤维及其可吸收的医用结构

    公开(公告)号：US07192437B2

    公开(公告)日：2007-03-20

    申请号：US09862093

    申请日：2001-05-21

    申请人： Shalaby W. Shalaby

    发明人： Shalaby W. Shalaby

    IPC分类号： A61L17/00 ,  A61B17/04 ,  C08G63/08

    CPC分类号： C08G63/64 ,  A61L17/12 ,  A61L27/18 ,  A61L31/06 ,  C08G63/08 ,  C08L67/04 ,  C08L69/00

    摘要： The present invention is directed to crystalline copolymers of l-lactide and a minor portion of a cyclic monomer, preferably ε-caprolactone or trimethylene carbonate or both. The present copolymers have a melting temperature of at least 150° C. and a crystallinity of at least 20%. Preferred are high molecular weight copolymers having an inherent viscosity of at least 1.1 dl/g. A variety of surgical constructs may be formed from the present copolymers. Surgical sutures made of mono- or multifilament yams of the present copolymers will bioabsorb in less than three years and will maintain at least 50% of their initial strength three weeks post-operatively.

    摘要翻译： 本发明涉及1-丙交酯和少部分环状单体的结晶共聚物，优选ε-己内酯或三亚甲基碳酸酯或两者。 本共聚物的熔融温度至少为150℃，结晶度至少为20％。 优选的是具有至少1.1dl / g的特性粘度的高分子量共聚物。 各种手术构建体可以由本发明的共聚物形成。 本发明共聚物的单丝或多丝纱线的手术缝合线将在不到三年的时间内生物吸收，术后3周将保持其初始强度的至少50％。

    Antimicrobial fabrics
    126.
    发明授权
    Antimicrobial fabrics 有权
    抗菌面料

    公开(公告)号：US06596657B1

    公开(公告)日：2003-07-22

    申请号：US09506046

    申请日：2000-02-17

    申请人： Shalaby W. Shalaby

    发明人： Shalaby W. Shalaby

    IPC分类号： B32B2704

    CPC分类号： D06M13/236 ,  A01N25/10 ,  A01N25/34 ,  A01N59/12 ,  D06M16/00 ,  D06M2101/20 ,  Y10T428/2915 ,  Y10T442/20 ,  Y10T442/2525 ,  Y10T442/2762 ,  Y10T442/2861 ,  Y10T442/2893 ,  Y10T442/2918 ,  Y10T442/60 ,  A01N31/16 ,  A01N33/12 ,  A01N47/44 ,  A01N59/16 ,  A01N63/02 ,  A01N2300/00

    摘要： The present invention is directed to surface functionalized fabrics, particularly those based on non-woven polypropylene, wherein the functional groups are capable of binding antimicrobial agents through ionic conjugation to control their release and prolong their antimicrobial activity. The invention also deals with Nylon 6 fabric that is complexed with iodine to control its release and to achieve prolonged antimicrobial activities. Similarly, polypropylene and cellulosic fabrics grafted with N-vinylpyrrolidone are disclosed. The N-vinylpyrrolidone can also complex with iodine to control its release and provide antimicrobial activity over desired periods of time.

    摘要翻译： 本发明涉及表面官能化织物，特别是基于非织造聚丙烯的织物，其中官能团能够通过离子缀合结合抗微生物剂以控制其释放并延长其抗微生物活性。 本发明还涉及与碘络合以控制其释放并实现延长的抗微生物活性的尼龙6织物。 类似地，公开了用N-乙烯基吡咯烷酮接枝的聚丙烯和纤维素织物。 N-乙烯基吡咯烷酮也可以与碘络合以控制其释放并在期望的时间段内提供抗微生物活性。

    Amorphous polymeric polyaxial initiators and compliant crystalline copolymers therefrom
    129.
    发明授权
    Amorphous polymeric polyaxial initiators and compliant crystalline copolymers therefrom 有权
    无定形聚合多轴引发剂和顺应性结晶共聚物

    公开(公告)号：US06462169B1

    公开(公告)日：2002-10-08

    申请号：US09698527

    申请日：2000-10-27

    申请人： Shalaby W. Shalaby

    发明人： Shalaby W. Shalaby

    IPC分类号： C08G6308

    CPC分类号： C08G63/64 ,  A61L17/12 ,  A61L31/06 ,  C08G63/08 ,  C08L67/04

    摘要： An absorbable crystalline, monocentric polyaxial copolymer comprising a central carbon or nitrogen atom and at least three axes, each of which includes an amorphous flexible component adjacent and originating from the central atom and a rigid, crystallizable component extending outwardly from the amorphous, flexible component is disclosed along with the use of such copolymer in medical devices which may contain a bioactive agent.

    摘要翻译： 包含中心碳原子或氮原子和至少三个轴的可吸收结晶的单中心多轴共聚物，每个轴包括邻近并源自中心原子的无定形柔性组分和从无定形柔性组分向外延伸的刚性可结晶组分。 公开了在可能含有生物活性剂的医疗装置中使用这种共聚物。

    Phosphonylated derivatives of aliphatic heterochain and acrylate erpolyms and applications thereof
    130.
    发明授权
    Phosphonylated derivatives of aliphatic heterochain and acrylate erpolyms and applications thereof 有权
    脂肪族杂链和丙烯酸酯的磷酸化衍生物及其应用

    公开(公告)号：US06395259B1

    公开(公告)日：2002-05-28

    申请号：US09464870

    申请日：1999-12-16

    申请人： Shalaby W. Shalaby

    发明人： Shalaby W. Shalaby

    IPC分类号： A61K716

    CPC分类号： C08F8/40 ,  C08G79/02

    摘要： A variety of phosphonylated heterochain polymers are disclosed, including, most preferably, phosphonylated polymethyl methacrylate. For each polymeric composition the phosphorous atom of a phosphorous-containing functional group is covalently bonded to a carbon atom of the polymeric chain. The phosphorous atoms are present in an amount of at least about 0.1 percent by weight in each polymeric composition.

    摘要翻译： 公开了各种膦酰化的杂链聚合物，包括最优选膦酰化的聚甲基丙烯酸甲酯。 对于每个聚合物组合物，含磷官能团的磷原子共价键合到聚合物链的碳原子上。 在每个聚合物组合物中，磷原子的存在量为至少约0.1重量％。