-
公开(公告)号:US20220218763A1
公开(公告)日:2022-07-14
申请号:US17709277
申请日:2022-03-30
Applicant: CHR. HANSEN A/S
Inventor: Dorthe SANDVANG , Tina STYRISHAVE
IPC: A61K35/742 , A23K50/75 , A23K10/18 , A61K9/00 , C12N1/20
Abstract: The present invention provides a Bacillus subtilis strain selected from the group consisting of a) the strain deposited as DSM32324,b) the strain deposited as DSM32325, and c) a mutant strain of (a) or (b) which has sensitivity for ampicillin, vancomycin, gentamicin, kanamycin, streptomycin, erythromycin, clindamycin, tetracycline, and chloramphenicol; and has inhibitory activity against E. coli and Clostridium perfringens. The invention further relates to Bacillus compositions comprising at least one Bacillus subtilis strain of the invention, preferably the Bacillus subtilis strain DSM32324 and/or the Bacillus subtilis strain DSM32325, as Direct Fed Microbial (DFM), premix, animal feed additive or animal feed. The invention provides a method of improving one or more animal performance parameters selected from the group consisting of i) increased weight gain (WG), ii) lower feed conversion ratio (FCR), iii) lower necrotic enteritis lesion scoring, iv) lower necrotic enteritis frequency, v) lower necrotic enteritis mortality, vi) increased European Production Efficacy Factor (EPEF), and vii) lower mortality, by feeding a strain or a composition according to the invention to an animal.
-
132.
公开(公告)号:US20220211062A1
公开(公告)日:2022-07-07
申请号:US17611416
申请日:2020-05-15
Applicant: Chr. Hansen A/S
Inventor: Surender Kumar DHAYAL , Martin LUND , Henrik BISGAARD-FRANTZEN , Johannes Maarten VAN DEN BRINK
Abstract: The present invention relates to methods for producing dairy food products modified with respect to their firmness and/or gelation time comprising cross-linked protein compounds and to methods for modifying said properties of said dairy food products, as well as to said modified dairy food products obtainable or obtained by such methods. Modification is achieved by in situ generation of H2O2 via carbohydrate oxidase, preferably cellobiose oxidase (EC 1.1.99.18), and cross-linking protein-tyrosine residues in a reaction using H202 via peroxidase (EC 1.11.1.7). Adding small phenolic compounds such as preferably p-coumaric acid or vanillin allows better control of the cross-linking reaction.
-
公开(公告)号:US11291695B2
公开(公告)日:2022-04-05
申请号:US16492897
申请日:2018-03-14
Applicant: CHR. HANSEN A/S
Inventor: Dorthe Sandvang , Tina Styrishave
IPC: A23K1/17 , A23K1/165 , A23K1/18 , A61K47/00 , A61K45/00 , A01N63/00 , A61K39/108 , A61K39/08 , A61K35/742 , A23K50/75 , A23K10/18 , A61K9/00 , C12N1/20 , C12R1/125
Abstract: The present invention provides a Bacillus subtilis strain selected from the group consisting of a) the strain deposited as DSM32324, b) the strain deposited as DSM32325, and c) a mutant strain of (a) or (b) which has sensitivity for ampicillin, vancomycin, gentamicin, kanamycin, streptomycin, erythromycin, clindamycin, tetracycline, and chloramphenicol; and has inhibitory activity against E. coli and Clostridium perfringens. The invention further relates to Bacillus compositions comprising at least one Bacillus subtilis strain of the invention, preferably the Bacillus subtilis strain DSM32324 and/or the Bacillus subtilis strain DSM32325, as Direct Fed Microbial (DFM), premix, animal feed additive or animal feed. The invention provides a method of improving one or more animal performance parameters selected from the group consisting of i) increased weight gain (WG), ii) lower feed conversion ratio (FCR), iii) lower necrotic enteritis lesion scoring, iv) lower necrotic enteritis frequency, v) lower necrotic enteritis mortality, vi) increased European Production Efficacy Factor (EPEF), and vii) lower mortality, by feeding a strain or a composition according to the invention to an animal.
-
134.
公开(公告)号:US20220061348A1
公开(公告)日:2022-03-03
申请号:US17389986
申请日:2021-07-30
Applicant: Chr. Hansen A/S
Inventor: Eric JOHANSEN , Kim Ib SOERENSEN , Mirjana CURIC-BAWDEN , Mette Pia JUNGE
Abstract: The dairy industry today faces a problem of providing an alternative to adding sweeteners to fermented milk products in order to achieve the desired sweet taste without the added calories. Furthermore, it would be highly advantageous to establish a method for reducing lactose in fermented milk products to a level which is acceptable for lactose-intolerant consumers. The above problems have been solved by providing mutant Streptococcus thermophilus strains and mutant Lactobacillus delbrueckii subsp. bulgaricus strains that excrete glucose to the milk when the milk is inoculated and fermented with such Streptococcus thermophilus strains and Lactobacillus delbrueckii subsp, bulgaricus strains. Thus, the present invention relates to strains of Streptococcus thermophilus and Lactobacillus delbrueckii subsp, bulgaricus which secrete glucose to the milk substrate during fermentation, as well as to mixed cultures comprising the Streptococcus thermophilus strains and the Lactobacillus delbrueckii subsp, bulgaricus strains, starter cultures comprising the strains and dairy products manufactured with the cultures. The present method also relates to use of the strains for decreasing the lactose content of a fermented food product and for boosting growth of the probiotic BB-12®.
-
公开(公告)号:US20210112837A1
公开(公告)日:2021-04-22
申请号:US17051852
申请日:2019-05-03
Applicant: Chr. Hansen A/S
Inventor: Birgitte YDE , Tina Malling THORSEN , George Nabin BAROI , Robin TAPONEN , Jakob SOELTOFT-JENSEN
IPC: A23L13/40 , C12N1/20 , C12N9/06 , A23L5/41 , A23B4/22 , A23L33/135 , A23L33/175 , A23L33/18 , A23L33/19 , A23L33/185 , A23L33/145 , A23L33/125
Abstract: The present invention is related to the field of reddening of food products. In particular the present invention relates to the preservation of nitrate reductase activity of frozen and/or dried lactic acid bacteria culture or Micrococcaceae culture.
-
公开(公告)号:US10945437B2
公开(公告)日:2021-03-16
申请号:US15346621
申请日:2016-11-08
Applicant: CHR. HANSEN A/S
Inventor: Abilio Alessandri , Inge Knap , Luciana Sekito De Freitas Zambelli
Abstract: The present invention refers to a composition comprising Bacillus subtilis (DSM 17231) and Bacillus licheniformis (DSM 17236) with nematicidal effect against phytonematodes on plants and/or its habitat, to its use and process for its preparation, use of Bacillus subtilis (DSM 17231) and Bacillus licheniformis (DSM 17236), processes for controlling, combating and conferring specific resistance to phytonematodes, and a kit.
-
公开(公告)号:US10941389B2
公开(公告)日:2021-03-09
申请号:US15755044
申请日:2016-08-31
Applicant: Chr. Hansen A/S
Inventor: Christian Jaeckel , Martin Lund , Enikö Fodor Hansen , Lone Riisberg , Iben Jeppesen , Johannes Maarten Van Den Brink
Abstract: Variants of chymosin with improved α S1-casein cleavage and C/P properties.
-
公开(公告)号:US20210032615A1
公开(公告)日:2021-02-04
申请号:US16998706
申请日:2020-08-20
Applicant: Chr. Hansen A/S
Inventor: Hans RAJ , Pernille SMITH , Thomas ECKHARDT , Vojislav VOJINOVIC , Charlotte Elisabeth Grüner SCHÖLLER , Johannes Maarten VAN DEN BRINK
Abstract: The present invention relates to new improved peptides and dimeric peptides exhibiting beta-galactosidase enzyme activity as well as methods using them for reducing the lactose content of milk-based compositions.
-
公开(公告)号:US10806157B2
公开(公告)日:2020-10-20
申请号:US15900603
申请日:2018-02-20
Applicant: Chr. Hansen A/S
Inventor: Johannes Maarten Van Den Brink , Martin Lund , Jonas Jacobsen , Sari Charlotte Hansen , Iben Jeppesen
IPC: C12N9/64 , C12N1/20 , C12N15/00 , C12P21/06 , C12P21/04 , C07H21/04 , A23C9/12 , C12N15/09 , A23C11/10 , A23C19/032 , A23C20/02 , A23K20/189 , C12N15/52
Abstract: Variants of chymosin with improved milk-clotting properties.
-
公开(公告)号:US10779552B2
公开(公告)日:2020-09-22
申请号:US14902946
申请日:2014-07-11
Applicant: Chr. Hansen A/S
Inventor: Martin Lund , Jonas Jacobsen , Johannes Maarten Van Den Brink
IPC: C12N9/64 , A23C19/032
Abstract: A liquid or dried granulated milk clotting aspartic protease enzyme composition and process for isolating a milk clotting aspartic protease enzyme of interest.
-
-
-
-
-
-
-
-
-