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    BACILLUS SUBTILIS STRAINS IMPROVING ANIMAL PERFORMANCE PARAMETERS
    131.
    发明申请
    BACILLUS SUBTILIS STRAINS IMPROVING ANIMAL PERFORMANCE PARAMETERS 有权

    公开(公告)号：US20220218763A1

    公开(公告)日：2022-07-14

    申请号：US17709277

    申请日：2022-03-30

    Applicant: CHR. HANSEN A/S

    Inventor： Dorthe SANDVANG ,  Tina STYRISHAVE

    IPC: A61K35/742 ,  A23K50/75 ,  A23K10/18 ,  A61K9/00 ,  C12N1/20

    Abstract: The present invention provides a Bacillus subtilis strain selected from the group consisting of a) the strain deposited as DSM32324,b) the strain deposited as DSM32325, and c) a mutant strain of (a) or (b) which has sensitivity for ampicillin, vancomycin, gentamicin, kanamycin, streptomycin, erythromycin, clindamycin, tetracycline, and chloramphenicol; and has inhibitory activity against E. coli and Clostridium perfringens. The invention further relates to Bacillus compositions comprising at least one Bacillus subtilis strain of the invention, preferably the Bacillus subtilis strain DSM32324 and/or the Bacillus subtilis strain DSM32325, as Direct Fed Microbial (DFM), premix, animal feed additive or animal feed. The invention provides a method of improving one or more animal performance parameters selected from the group consisting of i) increased weight gain (WG), ii) lower feed conversion ratio (FCR), iii) lower necrotic enteritis lesion scoring, iv) lower necrotic enteritis frequency, v) lower necrotic enteritis mortality, vi) increased European Production Efficacy Factor (EPEF), and vii) lower mortality, by feeding a strain or a composition according to the invention to an animal.

    Bacillus subtilis strains improving animal performance parameters
    133.
    发明授权
    Bacillus subtilis strains improving animal performance parameters 有权

    公开(公告)号：US11291695B2

    公开(公告)日：2022-04-05

    申请号：US16492897

    申请日：2018-03-14

    Applicant: CHR. HANSEN A/S

    Inventor： Dorthe Sandvang ,  Tina Styrishave

    IPC: A23K1/17 ,  A23K1/165 ,  A23K1/18 ,  A61K47/00 ,  A61K45/00 ,  A01N63/00 ,  A61K39/108 ,  A61K39/08 ,  A61K35/742 ,  A23K50/75 ,  A23K10/18 ,  A61K9/00 ,  C12N1/20 ,  C12R1/125

    Abstract: The present invention provides a Bacillus subtilis strain selected from the group consisting of a) the strain deposited as DSM32324, b) the strain deposited as DSM32325, and c) a mutant strain of (a) or (b) which has sensitivity for ampicillin, vancomycin, gentamicin, kanamycin, streptomycin, erythromycin, clindamycin, tetracycline, and chloramphenicol; and has inhibitory activity against E. coli and Clostridium perfringens. The invention further relates to Bacillus compositions comprising at least one Bacillus subtilis strain of the invention, preferably the Bacillus subtilis strain DSM32324 and/or the Bacillus subtilis strain DSM32325, as Direct Fed Microbial (DFM), premix, animal feed additive or animal feed. The invention provides a method of improving one or more animal performance parameters selected from the group consisting of i) increased weight gain (WG), ii) lower feed conversion ratio (FCR), iii) lower necrotic enteritis lesion scoring, iv) lower necrotic enteritis frequency, v) lower necrotic enteritis mortality, vi) increased European Production Efficacy Factor (EPEF), and vii) lower mortality, by feeding a strain or a composition according to the invention to an animal.

    USE OF LACTIC ACID BACTERIA FOR PREPARING FERMENTED FOOD PRODUCTS WITH INCREASED NATURAL SWEETNESS
    134.
    发明申请
    USE OF LACTIC ACID BACTERIA FOR PREPARING FERMENTED FOOD PRODUCTS WITH INCREASED NATURAL SWEETNESS 有权

    公开(公告)号：US20220061348A1

    公开(公告)日：2022-03-03

    申请号：US17389986

    申请日：2021-07-30

    Applicant: Chr. Hansen A/S

    Inventor： Eric JOHANSEN ,  Kim Ib SOERENSEN ,  Mirjana CURIC-BAWDEN ,  Mette Pia JUNGE

    IPC: A23C9/123 ,  C12N15/10 ,  C12N15/74 ,  C12N15/01 ,  C12N9/12 ,  C12N1/20 ,  A23C19/032

    Abstract: The dairy industry today faces a problem of providing an alternative to adding sweeteners to fermented milk products in order to achieve the desired sweet taste without the added calories. Furthermore, it would be highly advantageous to establish a method for reducing lactose in fermented milk products to a level which is acceptable for lactose-intolerant consumers. The above problems have been solved by providing mutant Streptococcus thermophilus strains and mutant Lactobacillus delbrueckii subsp. bulgaricus strains that excrete glucose to the milk when the milk is inoculated and fermented with such Streptococcus thermophilus strains and Lactobacillus delbrueckii subsp, bulgaricus strains. Thus, the present invention relates to strains of Streptococcus thermophilus and Lactobacillus delbrueckii subsp, bulgaricus which secrete glucose to the milk substrate during fermentation, as well as to mixed cultures comprising the Streptococcus thermophilus strains and the Lactobacillus delbrueckii subsp, bulgaricus strains, starter cultures comprising the strains and dairy products manufactured with the cultures. The present method also relates to use of the strains for decreasing the lactose content of a fermented food product and for boosting growth of the probiotic BB-12®.

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