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公开(公告)号:US10920203B2
公开(公告)日:2021-02-16
申请号:US15580853
申请日:2016-07-01
Applicant: NOVOZYMES A/S
Inventor: Carsten Hoerslev Hansen , Yitong Liu , Steffen Kayser , Vibeke Skovgaard Nielsen
Abstract: The present invention related to lipase variants having lipase activity and having between 60% to less than 100% sequence identity to a parent lipase or a fragment thereof, wherein the variant comprises one or more substitutions selected from H198A/D/E/F/G/I/L/N/Q/S/T/V/Y, F7H/K/R, F51A/I/L/V/Y, T143A/G/S/V, A150G/V, N200H/K/Q/R, I202G/L/V, S224C/F/H/I/L/P/Y, L227D/E/K/R, V228P, P229H/K/R, V230H/K/L/R, I255A/G/N/P/S/T/V/Y, P256A/K/N/Q/R/S/T/W, A257F/H/I/L/V/Y, L259F/Y, and W260D/E/F/H/I/L/N/Q/S/T/Y using SEQ ID NO:10 for position numbering or selected from H198A/D/E/F/G/I/L/N/Q/S/T/V/Y, F7H/K/R, F51A/I/L/V/Y, T143A/G/S/V, A150G/V, N200H/K/Q/R, I202G/L/V, S224C/F/H/I/L/P/Y, L227D/E/K/R, V228P, P229H/K/R, V230H/K/L/R, I255A/G/N/P/S/T/V/Y, T256A/K/N/Q/R/S/P/W, A257F/H/I/L/V/Y, L259F/Y, and W260D/E/F/H/I/L/N/Q/S/T/Y using SEQ ID NO:2 for position numbering. Further the invention relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; to compositions comprising the variants as well as methods of producing and using the variants.
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公开(公告)号:US20210040510A1
公开(公告)日:2021-02-11
申请号:US17072557
申请日:2020-10-16
Applicant: NOVOZYMES A/S
Inventor: Randy Deinhammer , Suzanne Clark , Mauricio Quiros , John Matthews , Anne Glud Hjulmand , Chee Leong Soong , Tomoko Matsui , Shinobu Takagi
IPC: C12P7/06
Abstract: The present invention relates to processes for producing fermentation products from starch-containing material, wherein a thermostable alpha-amylase and optionally a thermostable protease are present and/or added during liquefaction. The invention also relates to a composition suitable for use in a process of the invention.
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公开(公告)号:US20210024910A1
公开(公告)日:2021-01-28
申请号:US17041522
申请日:2019-03-27
Applicant: Novozymes A/S
Inventor: Rakhi Saikia , Naveen Shivanand Raikar , Padmavathi Balumuri , Jens Erik Nielsen
Abstract: The present invention relates to mannanase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
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公开(公告)号:US20210010010A1
公开(公告)日:2021-01-14
申请号:US17040906
申请日:2019-03-25
Applicant: Novozymes A/S
Inventor: Jean-Marie Mouillon , Pernille Hvid Christensen
IPC: C12N15/80
Abstract: The present invention relates to fungal host cells comprising nucleic acid constructs comprising a heterologous promoter operably linked to polynucleotidea encoding a chaperone, nucleic acid constructs comprising a polynucleotide encoding a chaperone, and methods for producing polypeptides of interest.
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公开(公告)号:US10889838B2
公开(公告)日:2021-01-12
申请号:US15507648
申请日:2015-08-27
Applicant: Novozymes A/S
Inventor: Henrik Bangsoe Nielsen , Lone Baekgaard , Joanna Wawrzynczyk , Hanne Soerensen , Lisa Rosgaard
IPC: C12P7/10 , C12N9/20 , C12N9/48 , C12N9/42 , C12N15/00 , C12N9/54 , C12N9/26 , C12N9/24 , C12N9/88 , C12P5/02 , C12P7/08 , C11D3/386
Abstract: The present invention relates to a method for solubilisation or hydrolysis of Municipal Solid Waste (MSW) with an enzyme blend and an enzyme composition for solubilization of Municipal Solid Waste (MSW), the enzyme composition comprising a cellulolytic background composition and a protease, lipase and/or beta-glucanase.
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公开(公告)号:US10829753B2
公开(公告)日:2020-11-10
申请号:US15776446
申请日:2016-11-24
Applicant: NOVOZYMES A/S
Inventor: Ye Liu , Xianzhi Jiang , Lan Tang , Astrid Benie , Henrik Frisner
Abstract: The present invention relates to isolated polypeptides having protease activity, and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
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公开(公告)号:US20200332227A1
公开(公告)日:2020-10-22
申请号:US16957436
申请日:2019-01-03
Applicant: Novozymes A/S
Abstract: Use of enzymes in preventing or removing air borne particulate matter from depositing on textile. The enzymes are preferably selected from a group consisting of DNase, protease, lipase, amylase, cellulase, and combinations thereof. The airborne particles comprise PM2.5 air pollutant, PM10 air pollutant, flying dust, sand storm dust, automobile exhaust, cigarette smoke, cooking smoke, and primary biological aerosol particles (PBAP).
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公开(公告)号:US20200318086A1
公开(公告)日:2020-10-08
申请号:US16652920
申请日:2018-11-07
Applicant: Novozymes A/S
Inventor: Carsten Anderson , Poul Erik Pedersen , Michael Dolberg Rasmussen , Carsten Hjort
Abstract: The present invention relates to temperature-sensitive variants of a Class-II Cas9 protein, polynucleotides encoding said variants, nucleic acid constructs and expression vectors comprising polynucleotides encoding said variants, host cells expressing said variant, methods of transient repression and expression of one or more genome target sequence using said variants, and use of said variants, polynucleotides, nucleic acid constructs, expression vectors, host cells, and methods.
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公开(公告)号:US20200318037A1
公开(公告)日:2020-10-08
申请号:US16652924
申请日:2018-10-15
Applicant: Novozymes A/S
Inventor: Albert E. Cervera-Padrell , Ole Simonsen , Alexander Findeisen , Poul Bach
Abstract: The invention provides layered granules comprising a core and a matrix coating surrounding the core. The matrix comprises a biological active and a non-volatile liquid, and may be applied using a fluidized bed spray coater (fluid-bed coating). The granules exhibit reduced release of biological active dust, such as enzyme dust, after subjecting the granules to mechanical stress.
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140.
公开(公告)号:US20200299662A1
公开(公告)日:2020-09-24
申请号:US16861471
申请日:2020-04-29
Applicant: NOVOZYMES A/S
Inventor: Zhengfang Kang , Kirk Matthew Schnorr , Lar Kobberøe Skov
Abstract: The present invention relates to polypeptides having trehalase activity. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using a trehalase of the invention, in particular a process of producing a fermentation product, such as ethanol.
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