公开(公告)号：US5798240A

公开(公告)日：1998-08-25

申请号：US584226

申请日：1996-01-11

Applicant: Susan A. Martinis ,  Mandana Sassanfar ,  Sunghoon Kim ,  Sang Ho Lee ,  Paul R. Schimmel

Inventor： Susan A. Martinis ,  Mandana Sassanfar ,  Sunghoon Kim ,  Sang Ho Lee ,  Paul R. Schimmel

IPC: A61K38/00 ,  C12N9/00 ,  C07H21/04 ,  C12N1/20 ,  C12N15/00

CPC classification number: C12N9/93 ,  A61K38/00 ,  Y10S435/863

Abstract: Isolated and/or recombinant nucleic acids encoding mycobacterial methionyl-tRNA synthetase have been characterized. Recombinant DNA constructs and vectors having a sequence which encodes mycobacterial methionyl-tRNA synthetase have been made, and can be used for the construction of tester strains as well as for the production of isolated and/or recombinant methionyl-tRNA synthetases. These enzymes or portions thereof are useful in the biochemical separation of methionine and quantification of methionine or ATP, and for producing antibodies useful in the purification and study of the enzyme, for example. Host cells and methods useful for producing recombinant mycobacterial methionyl-tRNA synthetases are described, as are tester strains, which are cells engineered to rely on the function of the tRNA synthetase encoded by an introduced cloned gene. Tester strains can be used to identify inhibitors of the essential tRNA synthetase enzyme encoded by the introduced cloned gene, and thus provide a means to assess the antimicrobial effect and specificity of the inhibitor without employing slow-growing, pathogenic strains of mycobacteria, such as Mycobacterium tuberculosis.

Abstract translation: 已经表征了编码分枝杆菌甲硫氨酰-tRNA合成酶的分离和/或重组核酸。 已经制备了具有编码分枝杆菌甲硫氨酰-tRNA合成酶的序列的重组DNA构建体和载体，并且可用于构建测试菌株以及用于分离和/或重组甲硫氨酰-tRNA合成酶的产生。 这些酶或其部分可用于甲硫氨酸的生物化学分离和甲硫氨酸或ATP的定量，以及用于产生用于纯化和研究酶的抗体。 描述了可用于产生重组分枝杆菌甲硫氨酰-tRNA合成酶的宿主细胞和方法，试验菌株是被依赖于引入的克隆基因编码的tRNA合成酶的功能而被工程化的细胞。 测试菌株可以用于鉴定由引入的克隆基因编码的必需tRNA合成酶的抑制剂，并且因此提供了评估抑制剂的抗微生物效果和特异性的方法，而不使用分枝杆菌的缓慢生长的致病菌株，例如分枝杆菌 结核。

公开(公告)号：US5777945A

公开(公告)日：1998-07-07

申请号：US886445

申请日：1997-07-01

Applicant: Jae-Kwang Sim ,  Sang-Ho Lee

Inventor： Jae-Kwang Sim ,  Sang-Ho Lee

IPC: G11C11/413 ,  G11C8/10 ,  G11C11/407 ,  G11C11/409 ,  H03M1/66 ,  G11C8/00

CPC classification number: G11C8/10

Abstract: A column decoding circuit for a semiconductor memory device includes a decoding unit and a pulse generating unit. The decoding unit decodes a selected column address and generates a selection signal. The pulse generating unit self-generates a pulse signal based on the selection signal output from the decoding unit. The pulse generating unit uses the self-generated pulse signal and the selection signal to output to a selected column switch a control signal having a minimum pulse width sufficient for selecting an associated column. Accordingly, a high speed read operation is performed by decreasing a loading and transmission time of the control signal. Further, power consumption of the column decoding circuit is decreased by self-generating the pulse signal, preferably based on the selection signal.

Abstract translation: 用于半导体存储器件的列解码电路包括解码单元和脉冲产生单元。 解码单元解码所选择的列地址并产生选择信号。 脉冲发生单元基于从解码单元输出的选择信号自生成脉冲信号。 脉冲发生单元使用自生成的脉冲信号，并且选择信号输出到选定的列切换具有足以选择相关列的最小脉冲宽度的控制信号。 因此，通过减小控制信号的负载和发送时间来执行高速读取操作。 此外，优选地基于选择信号，通过自发生脉冲信号来降低列解码电路的功耗。

公开(公告)号：US5689464A

公开(公告)日：1997-11-18

申请号：US600599

申请日：1994-04-19

Applicant: Jong Seuk Lee ,  Seung Min Kim ,  Jae Hyeoung Kim ,  Sang Ho Lee

Inventor： Jong Seuk Lee ,  Seung Min Kim ,  Jae Hyeoung Kim ,  Sang Ho Lee

IPC: G11C11/413 ,  G11C29/00 ,  G11C29/04 ,  G11C7/00

CPC classification number: G11C29/812 ,  G11C29/846

Abstract: A column repair circuit for a semiconductor memory having an input/output selection circuit for inputting a control signal, selecting a bit line and a bit bar line corresponding to a faulty memory cell and replacing the selected bit line and bit bar line with a spare bit line and a spare bit bar line. The input/output selection circuit includes an input stage for inputting the control signal, a spare bit line and a spare bit bar line, and a plurality of fuses each having one side connected to the input stage and other side connected to a plurality of resistors. The other side of the resistors are connected to ground for outputting the output signals. The input/output selection circuit further has a plurality of n-channel MOSFETs each including a gate connected to each of the other stages of the plurality of fuses via the resistors in a 2 to 1 manner for inputting the output signals. The drains of the MOSFETS are connected to the spare bit line and spare bit bar line and their sources are connected to each of the plurality of data bit lines and the plurality of data bit bar lines for functioning as a switch. Therefore, the present invention can provide the column repair circuit for a semiconductor memory which is capable of increasing its repair yield by adding the input/output selecting circuit enabling input/output selecting.

Abstract translation: 一种用于半导体存储器的列修复电路，具有用于输入控制信号的输入/输出选择电路，选择与故障存储器单元相对应的位线和位线，并用备用位替换所选位线和位线 线和备用位线。 输入/输出选择电路包括用于输入控制信号的输入级，备用位线和备用位线条，以及多个熔丝，每个熔丝具有连接到输入级的一侧和连接到多个电阻器的另一侧 。 电阻的另一侧连接到地，用于输出输出信号。 所述输入/输出选择电路还具有多个n沟道MOSFET，每个n沟道MOSFET包括通过所述电阻器以多个熔丝连接到所述多个熔丝中的每一个的栅极，以2:1的方式输入所述输出信号。 MOSFETS的漏极连接到备用位线和备用位线，并且它们的源极连接到用作开关的多个数据位线和多个数据位线中的每一个。 因此，本发明可以提供半导体存储器的列修复电路，该半导体存储器能够通过添加能够进行输入/输出选择的输入/输出选择电路来提高其修复产率。

公开(公告)号：US20250086859A1

公开(公告)日：2025-03-13

申请号：US18369216

申请日：2023-09-18

Applicant: Sang Ho Lee

Inventor： Sang Ho Lee

IPC: G06T11/60 ,  G06V10/774 ,  G06V10/82 ,  G06V40/10

Abstract: Disclosed are a user terminal, a server, and a method of operation capable of preserving and editing identity of an original image by performing user-customized learning on a pre-trained artificial neural network. The user terminal according to an embodiment includes an interface unit, a communication unit, and a control unit, in which the control unit may receive an original input image to be edited from a user and a text prompt including information about the editing, and transmit the received original input image to a server including a first artificial neural network trained to edit the input image according to the input text prompt, and receive, from the server, an output image for the original input image edited according to the text prompt by the first artificial neural network subjected to user-customized learning based on the original input image, and output the received output image through the interface unit.

公开(公告)号：US12246053B2

公开(公告)日：2025-03-11

申请号：US18407894

申请日：2024-01-09

Applicant: You Suk Youn ,  Young Jin Choi ,  Sang Ho Lee

Inventor： You Suk Youn ,  Young Jin Choi ,  Sang Ho Lee

IPC: A61K36/48 ,  A61K36/18 ,  A61K36/73 ,  A61K36/8969 ,  A61K36/899 ,  A61P25/04 ,  A61P29/00

Abstract: The pharmaceutical composition for treating or preventing neuropathic pain includes Polygonati rhizoma, Sorbus commixta Hedl., Geranium nepalense, and Glycine Semen Preparata.

公开(公告)号：US20220273454A1

公开(公告)日：2022-09-01

申请号：US17627322

申请日：2020-07-14

Applicant: Sang Ho LEE

Inventor： Sang Ho LEE ,  Ju Hee JANG

IPC: A61F2/44 ,  A61F2/46

Abstract: A cage to be inserted between vertebrae reduces a risk of damage to organs and nerves in the process of insertion surgery and facilitates the process of insertion surgery. The cage can be inserted in one insertion direction between a plurality of vertebrae, wherein the insertion direction forms a predetermined insertion angle with respect to the anterior aspect of the spine, and an upper surface and a lower surface of the cage are provided to correspond to a lower surface and an upper surface of the vertebrae. Also, the cage is stably fixed, and side effects after surgery is reduced. Also, the surgery time is reduced, and a burden on the patient is reduced. In addition, advantages of anterior insertion and direct lateral insertion are combined, and thus post-surgery outcomes in patients may be improved.

公开(公告)号：US20220249246A1

公开(公告)日：2022-08-11

申请号：US17626232

申请日：2020-07-13

Applicant: Sang Ho LEE ,  Sang Hyeop JEON ,  Jun Seok BAE ,  Young Sik BAE

Inventor： Sang Ho LEE ,  Sang Hyeop JEON ,  Jun Seok BAE ,  Young Sik BAE

IPC: A61F2/44

Abstract: Provided is a cage to be inserted into vertebrae. The cage configured to reduce a risk of organs, muscles, and nerves being injured during an insertion surgery process and to allow the insertion surgery process to be easily performed. To this end, the present invention provides a cage including a leading insertion portion which is inserted from the front of vertebrae to be in position between the vertebrae and a following insertion portion which is coupled to one surface of the leading insertion portion to be in position between the vertebrae. According to the present invention, there are effects of reducing a risk of organs, muscles, and nerves being injured during a surgery process of inserting the cage, facilitating the surgery process of inserting the cage, reducing post-surgery side effects by stably fixing the cage, and reducing a surgery time to reduce a burden to a patient.

公开(公告)号：US20220241419A1

公开(公告)日：2022-08-04

申请号：US17617540

申请日：2020-06-02

Applicant: Sang Ho Lee

Inventor： Sang Ho Lee

IPC: A61K41/00 ,  A61K47/52 ,  A61K47/69

Abstract: The present disclosure relates to highly dispersible zinc phthalocyanine-silica nanotubes and a preparation method thereof. More particularly, the present disclosure relates to highly dispersible zinc phthalocyanine-silica nanotubes capable of improving the dispersibility of zinc phthalocyanine so that the zinc phthalocyanine can be easily absorbed in the body, and to a method of preparing highly dispersible zinc phthalocyanine nanotubes. The present disclosure proposes a highly dispersible zinc phthalocyanine-silica nanotube and a method of preparing sample. The method includes a first step of mixing a template with a alcohol solution to prepare a nanotube solution containing a nanotube template, a second step of adding a zinc phthalocyanine (ZnPc) solution to the nanotube solution and stirring the resulting mixture to prepare a zinc phthalocyanine-silica nanotube solution, a third step of adding a silica precursor to the zinc phthalocyanine-nanotube solution and stirring the resulting mixture to induce silication, thereby preparing a zinc phthalocyanine-silica nanotube solution, and a fourth step of filtering and drying the zinc phthalocyanine-silica nanotube to prepare zinc phthalocyanine nanotube powder. Further proposed is a method of preparing the zinc phthalocyanine powder.

公开(公告)号：US09318111B2

公开(公告)日：2016-04-19

申请号：US13995085

申请日：2011-07-21

Applicant: Sang Ho Lee ,  Hoon Kim ,  Dong Ook Koo ,  Jun Seok Kim ,  Sang Kyong Kim

Inventor： Sang Ho Lee ,  Hoon Kim ,  Dong Ook Koo ,  Jun Seok Kim ,  Sang Kyong Kim

IPC: G10L15/22 ,  G10L15/30 ,  G10L15/08 ,  G10L15/01

CPC classification number: G10L15/22 ,  G10L15/01 ,  G10L15/08 ,  G10L15/30 ,  G10L2015/221

Abstract: A voice/speech recognition client system, a voice recognition server system, and a voice recognition method. The voice recognition system indicates a result of voice recognition in a voice signal inputted from a starting time for voice recognition to an ending time. The voice recognition client comprises: a communication unit that transmits a unit voice signal input at intervals from the starting time to the ending time, to the voice recognition server system at the intervals and receives an intermediate result of voice recognition from the voice recognition server system; and a display unit that displays the intermediate result received between the starting time and the ending time.

Abstract translation: 语音/语音识别客户端系统，语音识别服务器系统和语音识别方法。 语音识别系统指示从用于语音识别的开始时间到结束时间输入的语音信号中的语音识别的结果。 语音识别客户端包括：通信单元，其将从开始时间到结束时间的间隔输入的单位语音信号以间隔发送到语音识别服务器系统，并从语音识别服务器系统接收语音识别的中间结果 ; 以及显示单元，其显示在开始时间和结束时间之间接收到的中间结果。

公开(公告)号：US08976148B2

公开(公告)日：2015-03-10

申请号：US13602678

申请日：2012-09-04

Applicant: Hyun Suk Lee ,  Sang Ho Lee ,  Tah Joon Park ,  Kang Joo Kim

Inventor： Hyun Suk Lee ,  Sang Ho Lee ,  Tah Joon Park ,  Kang Joo Kim

IPC: G06F3/041

CPC classification number: G06F3/0416 ,  G06F3/044

Abstract: There are provided a data processing method and a touch sensing apparatus. The data processing method includes (a) obtaining a plurality of pieces of sensing data according to one or more touch inputs; (b) selecting one or more pieces of temporary reference data having the minimum difference value between adjacent other pieces of sensing data; (c) calculating difference values between the one or more pieces of temporary reference data; (d) calculating an N number of difference values between the N number of pieces of sensing data obtained from the nodes included in the Kth row and an N number of pieces of sensing data obtained from nodes included in the K-1th row; and (e) determining the temporary reference data having a relatively small representative value as reference sensing data of the Kth row.

Abstract translation: 提供了数据处理方法和触摸感测装置。 数据处理方法包括：（a）根据一个或多个触摸输入获得多条感测数据; （b）选择在相邻的其它感测数据之间具有最小差值的一个或多个临时参考数据; （c）计算一条或多条临时参考数据之间的差值; （d）计算从包括在第K行中的节点获得的N个感测数据中的N个差值的N个数和从包括在第K-1行中的节点获得的N个感测数据; 和（e）确定具有相对小的代表值的临时参考数据作为第K行的参考感测数据。