公开(公告)号：US2702306A

公开(公告)日：1955-02-15

申请号：US4874848

申请日：1948-09-10

Applicant: PENNSYLVANIA SALT MFG CO

Inventor： GALL JOHN F ,  INMAN CHARLES E

IPC: C07B39/00 ,  C07C17/00 ,  C07C45/63 ,  C07C46/00 ,  C07C201/12 ,  C07C205/12

CPC classification number: C07C201/12 ,  C07B39/00 ,  C07C17/00 ,  C07C45/63 ,  C07C46/00 ,  C07C205/12

公开(公告)号：US2601282A

公开(公告)日：1952-06-24

申请号：US2443048

申请日：1948-04-30

Applicant: UPJOHN CO

Inventor： HEINZELMANN RICHARD V

IPC: C07C201/12 ,  C07C205/04 ,  C07C205/32

CPC classification number: C07C201/12 ,  C07C205/04 ,  C07C205/32

公开(公告)号：US2545597A

公开(公告)日：1951-03-20

申请号：US78976247

申请日：1947-12-04

Applicant: US RUBBER CO

Inventor： ASHFORD WALTER R ,  BEATTIE ROBERT W

IPC: C07C201/12 ,  C07C205/37

CPC classification number: C07C201/12 ,  C07C205/37

公开(公告)号：US2483201A

公开(公告)日：1949-09-27

申请号：US60065445

申请日：1945-06-20

Applicant: COMMERCIAL SOLVENTS CORP

Inventor： HURD CHARLES D

IPC: C07C45/00 ,  C07C201/12 ,  C07C205/04

CPC classification number: C07C201/12 ,  C07C45/00 ,  C07C205/04

公开(公告)号：US2397384A

公开(公告)日：1946-03-26

申请号：US53852744

申请日：1944-06-02

Applicant: COMMERCIAL SOLVENTS CORP

Inventor： TINDALL JOHN B

IPC: C07C201/12 ,  C07C205/08

CPC classification number: C07C201/12 ,  C07C205/08

公开(公告)号：US20240279156A1

公开(公告)日：2024-08-22

申请号：US18413582

申请日：2024-01-16

Applicant: PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION

Inventor： Chang Sik HA ,  Jun Seok LEE ,  Sung Soo PARK ,  Jadhav Amol MARUTI

IPC: C07C217/84 ,  C07C201/12 ,  C07C213/02 ,  C08G73/10

CPC classification number: C07C217/84 ,  C07C201/12 ,  C07C213/02 ,  C08G73/105

Abstract: Disclosed are a novel diamine compound, a reactive monomer for a polyimide precursor containing the same, and a polyimide film manufactured therefrom. The novel diamine compound is represented by a following Chemical Formula 1:






where in the Chemical Formula 1, Ph represents a substituted or unsubstituted phenyl group.

公开(公告)号：US12030854B2

公开(公告)日：2024-07-09

申请号：US17296542

申请日：2020-07-21

Applicant: SOOCHOW UNIVERSITY

Inventor： Xiaobing Wan ,  Pengcheng Lian ,  Wenhao Long ,  Jingjing Li ,  Yonggao Zheng

IPC: C07D209/48 ,  C07B39/00 ,  C07C67/287 ,  C07C201/12 ,  C07C253/30 ,  C07C303/40 ,  C07C315/04

CPC classification number: C07D209/48 ,  C07B39/00 ,  C07C67/287 ,  C07C201/12 ,  C07C253/30 ,  C07C303/40 ,  C07C315/04

Abstract: The invention provides a method for producing a dichloro addition product of an aliphatic olefin by photocatalysis under visible light. The method includes reacting an aliphatic olefin as a substrate with hydrochloric acid as a chlorine source in an organic solvent under visible light irradiation in the presence of copper chloride with visible light absorption ability as a catalyst, to obtain the dichloro addition product of the aliphatic olefin, wherein the reaction is carried out under an oxygen-containing atmosphere, the aliphatic olefin comprises a carbon-carbon double bond and a C9-C15 aliphatic chain connected to the carbon-carbon double bond by a covalent bond. In the invention, visible light is used to provide the energy and a transition metal chloride with visible light absorption ability is used to undergo light-induced electron transfer from chloride with a reaction substrate, thereby initiating an addition reaction to obtain a dichloro addition product.

公开(公告)号：US11905232B2

公开(公告)日：2024-02-20

申请号：US17429183

申请日：2020-02-10

Applicant: Nogra Pharma Limited

Inventor： Salvatore Demartis ,  Francesca Viti ,  Marie McNulty

IPC: C07C231/10 ,  C07C201/12 ,  C07C205/56 ,  C07C231/18 ,  C07C233/54 ,  C07C231/02 ,  C07C227/04 ,  C07C303/28

CPC classification number: C07C231/10 ,  C07C201/12 ,  C07C205/56 ,  C07C227/04 ,  C07C231/02 ,  C07C231/18 ,  C07C233/54 ,  C07C303/28 ,  C07C201/12 ,  C07C205/56 ,  C07C303/28 ,  C07C309/66 ,  C07C227/04 ,  C07C229/42 ,  C07C231/02 ,  C07C233/54

Abstract: The disclosure provides a process for the preparation of 3-(4′-aminophenyl)-2-methoxypropionic acid, and analogs and intermediates thereof, contemplated to be capable of modulating the activity of receptors, e.g., PPARs receptors.

公开(公告)号：US20230303501A1

公开(公告)日：2023-09-28

申请号：US18128603

申请日：2023-03-30

Applicant: The USA, as represented by the Secretary, Dept. of Health and Human Services ,  Pontificia Universidad Católica de Chile

Inventor： Juan J. Marugan ,  Marc Ferrer ,  Noel T. Southall ,  Andres E. Dulcey ,  Xin Hu ,  Christopher R. Dextras ,  Daniel C. Talley ,  Alejandra Alvarez ,  Silvana Zanlungo ,  Rommy M. Von Bernhardi

IPC: C07D243/38 ,  A61P25/28 ,  A61P33/06 ,  A61P35/02 ,  A61P25/08 ,  A61K31/5513 ,  A61K31/553 ,  A61K31/554 ,  C07C201/12 ,  C07C227/22 ,  C07C319/14 ,  C07D267/18 ,  C07D267/20 ,  C07D281/16 ,  C07D401/04 ,  C07D403/04 ,  C07D413/04 ,  C07D413/10 ,  C07D413/14 ,  C07D417/04 ,  C07D471/04 ,  C07D487/04 ,  C07F5/02 ,  C07F7/08

CPC classification number: C07D243/38 ,  A61K31/5513 ,  A61K31/553 ,  A61K31/554 ,  A61P25/08 ,  A61P25/28 ,  A61P33/06 ,  A61P35/02 ,  C07C201/12 ,  C07C227/22 ,  C07C319/14 ,  C07D267/18 ,  C07D267/20 ,  C07D281/16 ,  C07D401/04 ,  C07D403/04 ,  C07D413/04 ,  C07D413/10 ,  C07D413/14 ,  C07D417/04 ,  C07D471/04 ,  C07D487/04 ,  C07F5/025 ,  C07F7/0812

Abstract: Disclosed herein are embodiments of a compound that inhibits c-Abl tyrosine kinase (also referred to herein as “c-Abl”). The compound embodiments described herein are novel c-Abl inhibitors that can bind to c-Abl at an allosteric site and inhibit its activity in various pathways. The compound embodiments also are capable of crossing the blood brain barrier and therefore are useful in inhibiting c-Abl activity as it affects pathways and/or proteins in the brain. The compound embodiments described herein are effective therapeutic agents for treating diseases involving c-Abl, such as cancers, motor neuron diseases, and neurodegenerative diseases. Also disclosed herein are embodiments of methods for making and using the c-Abl inhibitory compound embodiments.

公开(公告)号：US20230234900A1

公开(公告)日：2023-07-27

申请号：US17999273

申请日：2021-05-19

Applicant: University of Virginia Patent Foundation

Inventor： Thomas Brent Gunnoe ,  Xiaofan Jia ,  Lucas Isaac Frye

IPC: C07C2/84 ,  C07C41/30 ,  C07C17/266 ,  C07C201/12 ,  C07C253/30 ,  C07D307/36 ,  B01J31/22

CPC classification number: C07C2/84 ,  C07C41/30 ,  C07C17/266 ,  C07C201/12 ,  C07C253/30 ,  C07D307/36 ,  B01J31/2213 ,  B01J31/2291 ,  C07C2523/46 ,  B01J2531/822 ,  B01J2531/0208 ,  B01J2231/4261

Abstract: The present disclosure provides for a rhodium-catalyzed oxidative arene alkenylation from arenes and styrenes to prepare stilbene and stilbene derivatives. For example, the present disclosure provides for method of making arenes or substituted arenes, in particular stilbene and stilbene derivatives, from a reaction of an optionally substituted arene and/or optionally substituted styrene. The reaction includes a Rh catalyst or Rh pre-catalyst material and an oxidant, where the Rh catalyst or Rh catalyst formed Rh pre-catalyst material selectively functionalizes CH bond on the arene compound (e.g., benzene or substituted benzene).