-
161.发明申请公开(公告)号：US20210373036A1
公开(公告)日：2021-12-02
申请号：US17242780
申请日：2021-04-28
Inventor： Michael SIERKS , Stephanie WILLIAMS , Lalitha VENKATARAMAN
Abstract: The invention relates to antibodies, antibody fragments and binding agents that specifically recognize TDP-43 associated with frontotemporal dementia (FTD), but not TDP-43 associated with amyotrophic lateral sclerosis (ALS) or TDP-43 associated with healthy human brain tissue, and antibodies, antibody fragments and binding agents that specifically recognize TDP-43 associated with ALS, but not TDP-43 associated FTD or TDP-43 associated with healthy human brain tissue.
-
公开(公告)号：US11186835B2
公开(公告)日：2021-11-30
申请号：US16245984
申请日：2019-01-11
Inventor： Alexander A. Green
IPC: C12N9/00 , C12P21/02 , C07K14/005 , C07K14/47 , C12N15/113 , C12P7/64
Abstract: Provided herein, in some embodiments, are artificial ribosomes that synthesize nonribosomal peptides, polyketides, and fatty acids with full control over peptide sequence. Also provided herein are methods for programmed synthesis of nonribosomal peptides, polyketides, and fatty acids. In particular, provided herein are methods for scalable synthesis of a wide range of antibacterial, antifungal, antiviral, and anticancer compounds.
-
公开(公告)号：US20210359151A1
公开(公告)日：2021-11-18
申请号：US17285360
申请日：2019-10-14
Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY , BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA
Inventor： David FERRY , Vincent WHITESIDE , Ian R. SELLERS
IPC: H01L31/0735
Abstract: A photovoltaic device configured to substantially avoid radiative recombination of photo-generated carriers, reduce loss of energy of the photo-generated carriers through the phonon emission, extract photo-generated carriers substantially exclusively from the multi-frequency satellite valley(s) of the bandstructure of the used semiconductor material as opposed to the single predetermined extremum of the bandstructure. Methodologies of fabrication and operation of such a device.
-
公开(公告)号：US20210339858A1
公开(公告)日：2021-11-04
申请号：US17115677
申请日：2020-12-08
Inventor： Ivan Ermanoski
Abstract: An unmanned aerial vehicle (UAV) for gas transport is disclosed. The UAV includes a fuselage enclosing a volume, and a gas reservoir enclosed within the fuselage, filling at least a majority of the volume. The gas reservoir is configured to receive and store a gas at a pressure no greater than 100 bar. The UAV also includes a propulsion system having at least one engine, each of the at least one engine coupled to a prop that is driven by the at least one engine using energy derived from the gas stored in the gas reservoir. The UAV also includes a control system communicatively coupled to the propulsion system and configured to operate the unmanned aerial vehicle to autonomously transport the gas. The UAV may have a footprint while on the ground, and the footprint of the UAV may be no larger than three standard parking spaces.
-
公开(公告)号：US20210339023A1
公开(公告)日：2021-11-04
申请号：US17243564
申请日：2021-04-28
Inventor： Vishvak Rangarajan , Devin Dhooge , Kiryl Sheleg , Nicholas Holmes , Jeffrey Kleim , Bradley Greger , Shivanshi Shukla
Abstract: A system and method for the automatic stimulation of a vagus nerve for post-stroke rehabilitation is disclosed. The system includes an application subsystem having an electrode positioned to stimulate the vagus nerve and coupled to a user outside of a surgical setting. The system also includes a waveform generator communicatively coupled to the electrode, and a triggering subsystem including a receiver configured to detect the presence of a tag. The triggering subsystem is communicatively coupled to waveform generator and is configured to automatically trigger the stimulation of the vagus nerve upon detecting the presence of the tag. The tag is located proximate a rehabilitation context such that the tag is detected when the user is using the rehabilitation context, resulting in the vagus nerve of the user being automatically stimulated by the electrode in response to the user's post-stroke rehabilitation training.
-
Patent Agency Ranking
公开(公告)号：US11164067B2
公开(公告)日：2021-11-02
申请号：US16556130
申请日：2019-08-29
Inventor： Jianming Liang , Zongwei Zhou , Md Mahfuzur Rahman Siddiquee , Nima Tajbakhsh
Abstract: Disclosed are provided systems, methods, and apparatuses for implementing a multi-resolution neural network for use with imaging intensive applications including medical imaging. For example, a system having means to execute a neural network model formed from a plurality of layer blocks including an encoder layer block which precedes a plurality of decoder layer blocks includes: means for associating a resolution value with each of the plurality of layer blocks; means for processing via the encoder layer block a respective layer block input including a down-sampled layer block output processing, via decoder layer blocks, a respective layer block input including an up-sampled layer block output and a layer block output of a previous layer block associated with a prior resolution value of a layer block which precedes the respective decoder layer block; and generating the respective layer block output by summing or concatenating the processed layer block inputs.
-
公开(公告)号：US11164021B2
公开(公告)日：2021-11-02
申请号：US16875680
申请日：2020-05-15
Inventor： Md Mahfuzur Rahman Siddiquee , Zongwei Zhou , Ruibin Feng , Nima Tajbakhsh , Jianming Liang
Abstract: Methods, systems, and media for discriminating and generating translated images are provided. In some embodiments, the method comprises: identifying a set of training images, wherein each image is associated with at least one domain from a plurality of domains; training a generator network to generate: i) a first fake image that is associated with a first domain; and ii) a second fake image that is associated with a second domain; training a discriminator network, using as inputs to the discriminator network: i) an image from the set of training images; ii) the first fake image; and iii) the second fake image; and using the generator network to generate, for an image not included in the set of training images at least one of: i) a third fake image that is associated with the first domain; and ii) a fourth fake image that is associated with the second domain.
-
公开(公告)号：US11154606B2
公开(公告)日：2021-10-26
申请号：US16628860
申请日：2018-07-02
Inventor： Kenneth Roland , Andrew Diamos , Hugh Mason
Abstract: In certain embodiments, the present invention provides a poultry vaccine comprising an antigenic protein comprising a PlcC protein unit that is operably linked to a peptide linker that is operably linked to a NetB protein unit, where the vaccine is effective in stimulating a protective cellular and/or humoral immune response to C. perfringens. Methods are also provided for making the vaccine and for vaccinating poultry by administering such a vaccine.
-
公开(公告)号：US20210324060A1
公开(公告)日：2021-10-21
申请号：US17327462
申请日：2021-05-21
Inventor： Michael SIERKS , Huilai TIAN
Abstract: The invention relates to antibodies, antibody fragments and binding agents that specifically recognize oligomeric tau but do not bind to monomeric tau, fibrillar tau or non-disease associated forms of tau.
-
公开(公告)号：US20210313085A1
公开(公告)日：2021-10-07
申请号：US17350464
申请日：2021-06-17
Inventor： William Graves
IPC: G21K1/06
Abstract: An optical apparatus is provided for manipulating light from x-ray sources (e.g., free electron lasers). In some embodiments, the optical apparatus includes a first capillary optic having a first longitudinal axis and a second capillary optic having a second longitudinal axis that is angled with respect to the first longitudinal axis. The second capillary optic is positioned to receive light directly from the first capillary optic.
-
-
-
-
-
-
-
-
-
Search Results
1764
records
(took 0.04 seconds)
