System and method for cuffless blood pressure estimation

    公开(公告)号:US11006888B2

    公开(公告)日:2021-05-18

    申请号:US15939119

    申请日:2018-03-28

    Abstract: Disclosed is a system for estimating arterial blood pressure. The system includes a heartbeat detection module configured to receive an electrocardiogram signal, and detect one or more QRS complexes of the electrocardiogram signal. The system also includes a photoplethysmographic sensor module configured to trigger a light emitter, thereby generating a plurality of samples of a photoplethysmographic signal. Further, the system includes a blood pressure calculation module configured to receive information about the detected one or more QRS complexes and the plurality of photoplethysmographic signal samples, and calculate at least one blood pressure value based on a pulse arrival time period between the electrocardiogram and the photoplethysmographic signal. Additionally, the photoplethysmographic sensor module is further configured to receive information about the detected one or more QRS complexes, trigger, each time a QRS complex is detected, the generation of the plurality of photoplethysmographic signal samples, and determine a photoplethysmographic signal acquisition period.

    SINGLE-PHOTON AVALANCHE DIODE AND A SENSOR ARRAY

    公开(公告)号:US20210119069A1

    公开(公告)日:2021-04-22

    申请号:US17030203

    申请日:2020-09-23

    Abstract: A single-photon avalanche diode (SPAD) is disclosed. In one aspect, the SPAD comprises an inner doped region, a geometrical structure of a boundary of the inner doped region rotationally symmetric in a horizontal direction of a substrate; at least one outer doped region connected to a second terminal, the at least one outer doped region arranged to at least partially enclose the inner doped region and the outer doped region comprising dopant implantations of a different type than the inner doped region; a lowly doped depletion volume arranged to surround the inner doped region, a depth of the lowly doped depletion volume extending from the top surface of the substrate into the substrate being larger than a depth of the at least one outer doped region, and when a reverse bias is applied to an anode, an electric field peak around the inner doped region being formed to enable impact ionization and multiplication of charges.

    HOLOGRAPHIC IMAGING DEVICE AND METHOD

    公开(公告)号:US20210116863A1

    公开(公告)日:2021-04-22

    申请号:US17033123

    申请日:2020-09-25

    Applicant: IMEC vzw

    Abstract: A holographic imaging device is disclosed. In one aspect, the holographic imaging device comprises an imaging unit comprising at least two light sources, wherein the imaging unit is configured to illuminate an object by emitting at least two light beams with the at least two light sources. A first and second light beams have different wave-vectors and wavelengths. The holographic imaging device further comprises a processing unit configured to obtain at least two holograms of the object by controlling the imaging unit to sequentially illuminate the object with respectively the first light beam and the second light beam, construct at least two 2D image slices based on the at least two holograms, wherein each 2D image slice is constructed at a determined depth within the object volume, and generate a three-dimensional image of the object based on a combination of the 2D image slices.

    Method for producing an image sensor, and an image sensor

    公开(公告)号:US10985200B2

    公开(公告)日:2021-04-20

    申请号:US16234472

    申请日:2018-12-27

    Applicant: IMEC VZW

    Abstract: A method for producing an image sensor comprises: depositing a first back-end-of-line, BEOL, layer above a substrate comprising an array of light-detecting elements, said BEOL layer comprising metal wirings being arranged to form connections to components on the substrate and together with depositing the first BEOL layer, improving planarization of the first BEOL layer by depositing a planarizing metal dummy pattern in the first BEOL layer, wherein a part of the planarizing metal dummy pattern is arranged above a light-detecting element, wherein the planarizing metal dummy patterns is formed from the same material as the metal wirings and is deposited to planarize density of the metal deposited in the first BEOL layer across a surface of the layer and wherein a shape and/or position of the metal dummy pattern above the array of light-detecting elements is designed to provide a desired effect on incident light.

    ELECTRODE ARRANGEMENT FOR STIMULATING AND RECORDING ELECTRICAL SIGNALS IN BIOLOGICAL MATTER, A NEURAL PROBE, A MICRO-ELECTRODE ARRAY AND A METHOD FOR CONTROLLING AN ELECTRODE ARRANGEMENT

    公开(公告)号:US20210085980A1

    公开(公告)日:2021-03-25

    申请号:US17031733

    申请日:2020-09-24

    Applicant: IMEC VZW

    Abstract: An electrode arrangement for stimulating and recording electrical signals in biological matter comprises: an array (110) of electrodes (112), wherein electrodes (112) are configured to be switchable between stimulating and recording of electrical signals; a control unit (120), wherein the control unit (120) is configured to select a plurality of electrodes (112) to form a combined macroelectrode site (114) for providing a stimulating signal, wherein the control unit (120) is further configured to determine a perimeter electrode (112b) and a central electrode (112a), wherein the perimeter electrode (112b) is arranged at a perimeter of the combined macroelectrode site (114) and the central electrode (112a) is arranged centrally within the combined macroelectrode site (114), and wherein the control unit (120) is further configured to provide a stimulation signal to the perimeter electrode (112b) that has a lower magnitude than a stimulation signal provided to the central electrode (112a).

    Method of forming target layer surrounding vertical nanostructure

    公开(公告)号:US10957793B2

    公开(公告)日:2021-03-23

    申请号:US16128386

    申请日:2018-09-11

    Applicant: IMEC vzw

    Abstract: The disclosed technology generally relates to semiconductor fabrication, and more particularly to a method of forming a target layer surrounding a vertical nanostructure. In one aspect, a method includes providing a substrate having a substrate surface. The method additionally includes forming a vertical nanostructure extending outwardly from a substrate surface. The vertical nanostructure has a sidewall surface, where the sidewall surface has an upper portion and a lower portion. The method additionally includes forming a target layer at least along the sidewall surface of the vertical nanostructure and on the substrate surface. The method additionally includes forming a protection layer covering the target layer and removing an upper portion of the protection layer, thereby exposing the target layer along the upper portion of the sidewall surface of the vertical nanostructure. Thereafter, the exposed target layer is removed along the upper portion of the sidewall surface of the vertical nanostructure selective towards the protection layer. Thereafter, the remaining protection layer is removed.

    Isolated Vertical Nanowire
    169.
    发明申请

    公开(公告)号:US20210074830A1

    公开(公告)日:2021-03-11

    申请号:US17013230

    申请日:2020-09-04

    Applicant: IMEC VZW

    Abstract: A method for electrically isolating a vertical nanowire on at least one location in the nanowire. The method comprises providing a substrate, forming a vertical nanowire stack on the substrate. The stack comprises at least one nanowire section of a first material. A sacrificial section of a second material is provided in the vertical nanowire stack on the at least one location. The second material is selected such that it can be selectively removed with respect to the first material. The method, moreover, comprises creating at least one interconnect to the at least one nanowire section which should be isolated, removing the at least one sacrificial section and replacing it with an isolating section after creating the interconnect.

    Phase Difference Measurement Device for Optical Phased Arrays

    公开(公告)号:US20210063840A1

    公开(公告)日:2021-03-04

    申请号:US16998551

    申请日:2020-08-20

    Applicant: IMEC VZW

    Abstract: A phase difference measurement device comprises at least two optical waveguides arranged in parallel in a first plane. Each optical waveguide comprises a proximal portion and a distal portion. The proximal portion of at least one of the optical waveguides comprises a phase-shifting device configured to induce a phase shift of a light wave being transmitted in the phase difference measurement device. The device further comprises at least one phase interrogator device arranged in the first plane between two neighboring optical waveguides of the optical waveguides. The phase interrogator device is configured to couple light from the two neighboring optical waveguides to interfere in the phase interrogator to generate an interference light wave. At least one photodetector is arranged for detecting the interference light wave. The photodetector is arranged in a second plane other than the first plane.

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