摘要:
Antisense compounds, compositions and methods are provided for modulating the expression of superoxide dismutase 1, soluble. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding superoxide dismutase 1, soluble. Methods of using these compounds for modulation of superoxide dismutase 1, soluble expression and for treatment of diseases associated with expression of superoxide dismutase 1, soluble are provided.
摘要:
The invention is a message distribution system that can deliver a single message to a large number of people with a single act using a group of computer servers. The preferred embodiment requires the user to establish an account using a website and enter a contact list. The contact list can include both email addresses and telephone numbers. When the user wishes to send a message, at a later time, the user contacts the group of computer servers by a telephone number or email address. The user records a message on the servers and the server sends the messages to all email addresses and telephone numbers on the contact list for that user. Other embodiments include procedures to confirm the validity of the email addresses and telephone numbers and to confirm the delivery of messages to the email address and telephone numbers on the contact list.
摘要:
Apparatus for detecting the breaking of a contact-sensitive surface includes an acoustic, shock, and vibration transducer, a detector circuit responsive to the transducer for detecting an acoustic wave resulting from a contact force applied to the surface and generating a signal, a support for the transducer, and the means for disqualifying a contact force to the support as a breakage event that relies on differentiation of the speed with which a shock wave travels through a solid material versus the speed with which an acoustic wave travels through air. The transducer may include a front electret condenser microphone and in some preferred embodiments the microphone does not have a preamplifier associated therewith. The invention also includes the method for detecting the breaking of a contact-sensitive surface that includes providing an acoustic, shock, and vibration transducer, providing a support for the transducer, providing a detector circuit responsive to the transducer for detecting an acoustic wave resulting from a contact force applied to the surface and generating a signal; and providing means for disqualifying a contact force to the support as a breakage event that relies on differentiation of the speed with which a shock wave travels through a solid material versus the speed with which an acoustic wave travels through air.
摘要:
A multi-sectional percussive drill bit assembly for drilling holes in earth formation primarily used in conjunction with a pneumatic percussive device. The drill bit assembly is comprised of an easily removable bit that is rotationally driven by a lug and pocket structure and axially limited in travel by means of retaining members.
摘要:
The present invention relates to a device for separation and characterization of gas-phase ions. The device incorporates an ion source, a field asymmetric waveform ion mobility spectrometry (FAIMS) analyzer, an ion mobility spectrometry (IMS) drift tube, and an ion detector. In one aspect of the invention, FAIMS operating voltages are electrically floated on top of the IMS drift voltage. In the other aspect, the FAIMS/IMS interface is implemented employing an electrodynamic ion funnel, including in particular an hourglass ion funnel. The present invention improves the efficiency (peak capacity) and sensitivity of gas-phase separations; the online FAIMS/IMS coupling creates a fundamentally novel two-dimensional gas-phase separation technology with high peak capacity, specificity, and exceptional throughput.
摘要:
A hand held retractable abrasive sharpener having a rod formed with a tapered end portion and a partially cylindrical opposite end portion. A part of the partially cylindrical opposition end portion is flat. A slot is formed in the rod. Substantially all of the outer surfaces include layers of the rod have an abrasive material. The rod is carried in a carrying case for tansport and storage in a locked relationship and being capable of being released and withdrawn for sharpening with carrying case serving as a holder.
摘要:
A hose (10) comprising a tubular body (12) of flexible material arranged between an inner and an outer helically wound wire (22, 24). The hose (10) further comprises an elongate member having opposing longitudinal edges, the elongate member being helically wound around the tubular body such that the opposing longitudinal edges of the layer are in an adjacent or overlapping arrangement, wherein each longitudinal edge includes a formation capable of interengaging with a cooperating formation on the opposing longitudinal edge.
摘要:
Method for making a dual-textured food substrate having large seasoning bits whereby the bits are substantially adhered to the food substrate, or chip. A first topping comprising large seasoning bits and a dry adhesive is applied to a cooked chip having a first texture. The topped, cooked chip is then heated to a temperature such that the dry adhesive undergoes a glass transition and flows down around the bit to the bit and food substrate contact point. The topped, cooked chip is then subjected to changed process conditions, such as cooling, the adhesive hardens, and a bond is formed between the chip and the seasoning bits. A second topping having a second texture is then placed and melted onto the chip. The food ingredient properties are optimized to provide a shelf-stable dual-textured food product.
摘要:
High electron mobility transistors are provided that include a non-uniform aluminum concentration AlGaN based cap layer having a high aluminum concentration adjacent a surface of the cap layer that is remote from the barrier layer on which the cap layer is provided. High electron mobility transistors are provided that include a cap layer having a doped region adjacent a surface of the cap layer that is remote from the barrier layer on which the cap layer is provided. Graphitic BN passivation structures for wide bandgap semiconductor devices are provided. SiC passivation structures for Group III-nitride semiconductor devices are provided. Oxygen anneals of passivation structures are also provided. Ohmic contacts without a recess are also provided.
摘要:
A system is disclosed for providing a new panel antenna array with enhanced environmental protection, increased reliability and simplified assembly through the incorporation of new array structures. In one embodiment, a panel antenna array system comprises one or more linear arrays having one or more radiating elements for providing antenna transmission and reception; and one or more protection modules to be aligned vertically with each other in a parallel fashion, with each protection module providing protection to one linear array. A mounting bracket further provides a mounting surface to the protection modules.