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公开(公告)号：US20050002897A1
公开(公告)日：2005-01-06
申请号：US10872198
申请日：2004-06-18
Applicant: Ulrich Haupts , Andre Koltermann , Andreas Scheidig , Christian Votsmeier , Ulrich Kettling
Inventor： Ulrich Haupts , Andre Koltermann , Andreas Scheidig , Christian Votsmeier , Ulrich Kettling
CPC classification number: C12N9/6427 , A61K38/482 , A61K38/4826 , A61K38/486 , A61K38/4873 , A61K38/488 , C12P21/06 , C12Q1/37
Abstract: The present invention provides method for the treatment of a disease by applying a medicament comprising a protease with a defined specificity is capable to hydrolyze specific peptide bonds within a target substrate related to such disease. The proteases with such a defined specificity can further be used for related therapeutic or diagnostic purposes.
Abstract translation: 本发明提供了通过应用包含具有确定的特异性的蛋白酶的药物能够水解与这种疾病相关的靶基质内的特异性肽键来治疗疾病的方法。 具有这种确定的特异性的蛋白酶可进一步用于相关的治疗或诊断目的。
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公开(公告)号：US20140045217A1
公开(公告)日：2014-02-13
申请号：US13997593
申请日：2012-01-02
Applicant: Klaudija Milos , Claudia Stamme , Tanja Lindner , Vitaly Svetlichny , Andreas Scheidig
Inventor： Klaudija Milos , Claudia Stamme , Tanja Lindner , Vitaly Svetlichny , Andreas Scheidig
IPC: C12P7/26
Abstract: The present disclosure provides novel methods and compositions for improved production processes of algae cell components. In particular the present disclosure relates to methods for improving the extractability of algae cellular compositions.
Abstract translation: 本公开提供了用于改进藻类细胞组分的生产方法的新方法和组合物。 特别地，本公开涉及用于改善藻类细胞组合物的提取能力的方法。
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Patent Agency Ranking
公开(公告)号：US20130344576A1
公开(公告)日：2013-12-26
申请号：US13997647
申请日：2012-01-02
Applicant: Klaudija Milos , Claudia Stamme , Tanja Lindner , Vitaly Svetlichny , Andreas Scheidig
Inventor： Klaudija Milos , Claudia Stamme , Tanja Lindner , Vitaly Svetlichny , Andreas Scheidig
IPC: C12N1/06
Abstract: The technology disclosed herein relates to novel methods and compositions for the production processes of algae cell components from algae of the genus Scenedesmus. The extractability of algae cellular components is improved and the process is optimized and accelerated by using the enzyme compositions according to the present invention.
Abstract translation: 本文公开的技术涉及用于来自鲨叶藻藻类的藻类细胞成分的生产方法的新方法和组合物。 通过使用根据本发明的酶组合物，藻类细胞成分的提取能力得到改善并且该方法被优化和加速。
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公开(公告)号：US20120237496A1
公开(公告)日：2012-09-20
申请号：US13378764
申请日：2010-06-21
Applicant: Joerg Birkenfeld , Andrea Eicker , Per-Ola Freskgard , Claudia Gotzberger-Schad , Joanna Grudzinska , Ulrich Haupts , Josi Innig , Christoph Mahlert , Andreas Scheidig , Michael Strerath , Jan Tebbe , Johan Per-Wallin , Nina Wobst , Carl Innes Webster , Lutz Jermutus
Inventor： Joerg Birkenfeld , Andrea Eicker , Per-Ola Freskgard , Claudia Gotzberger-Schad , Joanna Grudzinska , Ulrich Haupts , Josi Innig , Christoph Mahlert , Andreas Scheidig , Michael Strerath , Jan Tebbe , Johan Per-Wallin , Nina Wobst , Carl Innes Webster , Lutz Jermutus
IPC: A61K38/48 , C12N9/96 , C12N5/10 , A61P25/28 , C12N1/19 , C12N15/63 , C12N15/57 , C12N9/64 , C12N1/15
CPC classification number: C12N9/6494 , A61K38/00 , C12Y304/24011
Abstract: The present invention relates to polypeptides comprising protease variants of wild type human neprilysin having an altered specificity and/or activity. In particular the present invention relates to polypeptides comprising protease variants derived from human neprilysin having an increased specificity and/or activity against certain substrates, in particular against amyloid beta.
Abstract translation: 本发明涉及包含具有改变的特异性和/或活性的野生型人体炎蛋白的蛋白酶变体的多肽。 特别地，本发明涉及包含衍生自人尼泊金的蛋白酶变体的多肽，其具有针对某些底物，特别是针对淀粉样β的特异性和/或活性增加。
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公开(公告)号：US20080064064A1
公开(公告)日：2008-03-13
申请号：US11778690
申请日：2007-07-17
Applicant: Oliver Kensch , Wayne Coco , Andreas Scheidig , Ute Beister , Birgitta Leuthner , Nadine Koch , Markus Rarbach , Ulrich Kettling , Ulrich Haupts
Inventor： Oliver Kensch , Wayne Coco , Andreas Scheidig , Ute Beister , Birgitta Leuthner , Nadine Koch , Markus Rarbach , Ulrich Kettling , Ulrich Haupts
IPC: C12P21/04 , A23F5/24 , A23K1/14 , C07H21/04 , C09K8/60 , C11D7/42 , C12N15/00 , C12N5/06 , C12N9/48
CPC classification number: C11D3/38636 , A23F5/246 , A23K20/189 , A23L29/06 , C09K8/68 , C12N9/2494 , C12Y302/01078
Abstract: The present invention provides an insertion, deletion and/or substitution mutein of wild-type Trichoderma reesei β-mannanase having enhanced thermostability, proteolytic stability, specific activity and/or stability at low pH, a nucleic acid molecule encoding said mannanase mutein, a composition comprising said mannanase mutein; a method for its preparation, and its use for food and feed processing, for coffee extraction and the processing of coffee waste, as a supplement to food and feed, for enzyme aided bleaching of paper pulps, as bleaching and/or desizing agent in textile industry, for oil and gas well stimulation by hydraulic fracturing, as detergent, for removal of biofilms and in delivery systems, or for the processing of renewable resources intended for the production of biological fuels.
Abstract translation: 本发明提供了具有增强的热稳定性，蛋白水解稳定性，比较活性和/或低pH稳定性的野生型里氏木霉β-甘露聚糖酶的插入，缺失和/或取代突变蛋白，编码所述甘露聚糖酶突变蛋白的核酸分子，组合物 包含所述甘露聚糖酶突变蛋白; 其制备方法及其用于食品和饲料加工的咖啡提取和咖啡废弃物的加工，作为食品和饲料的补充，用于纸浆的酶辅助漂白，作为纺织品中的漂白和/或脱浆剂 工业，通过水力压裂的油气井刺激，作为洗涤剂，用于去除生物膜和输送系统，或用于处理用于生产生物燃料的可再生资源。
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公开(公告)号：US20060236426A1
公开(公告)日：2006-10-19
申请号：US10476107
申请日：2002-04-25
Applicant: Jens Kossmann , Andreas Scheidig , Anja Froehlich
Inventor： Jens Kossmann , Andreas Scheidig , Anja Froehlich
CPC classification number: C12N9/2411 , C12N9/2408 , C12N9/2414 , C12N9/2422 , C12N15/8245
Abstract: Nucleic acid molecules encoding starch degrading enzymes are provided. Moreover, vectors, host cells and plant cells transformed by the herein-described nucleic acid molecules and plants containing them are provided. Furthermore, methods are described for preparing transgenic plants which show increased or reduced starch degradation.
Abstract translation: 提供编码淀粉降解酶的核酸分子。 此外，提供了通过本文描述的核酸分子和含有它们的植物转化的载体，宿主细胞和植物细胞。 此外，描述了制备显示增加或降低的淀粉降解的转基因植物的方法。
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公开(公告)号：US20050175581A1
公开(公告)日：2005-08-11
申请号：US11021951
申请日：2004-12-22
Applicant: Ulrich Haupts , Andre Koltermann , Andreas Scheidig , Christian Votsmeier , Ulrich Kettling , Wayne Coco
Inventor： Ulrich Haupts , Andre Koltermann , Andreas Scheidig , Christian Votsmeier , Ulrich Kettling , Wayne Coco
CPC classification number: C12N9/6427 , A61K38/482 , A61K38/4826 , A61K38/486 , A61K38/4873 , A61K38/488 , C12P21/06 , C12Q1/37
Abstract: The present invention provides method for the treatment of a disease by applying a medicament comprising a protease with a defined specificity is capable to hydrolyze specific peptide bonds within a target substrate related to such disease. The proteases with such a defined specificity can further be used for related therapeutic or diagnostic purposes.
Abstract translation: 本发明提供了通过应用包含具有确定的特异性的蛋白酶的药物能够水解与这种疾病相关的靶基质内的特异性肽键来治疗疾病的方法。 具有这种确定的特异性的蛋白酶可进一步用于相关的治疗或诊断目的。
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