公开(公告)号：US20080064064A1

公开(公告)日：2008-03-13

申请号：US11778690

申请日：2007-07-17

申请人： Oliver Kensch ,  Wayne Coco ,  Andreas Scheidig ,  Ute Beister ,  Birgitta Leuthner ,  Nadine Koch ,  Markus Rarbach ,  Ulrich Kettling ,  Ulrich Haupts

发明人： Oliver Kensch ,  Wayne Coco ,  Andreas Scheidig ,  Ute Beister ,  Birgitta Leuthner ,  Nadine Koch ,  Markus Rarbach ,  Ulrich Kettling ,  Ulrich Haupts

IPC分类号： C12P21/04 ,  A23F5/24 ,  A23K1/14 ,  C07H21/04 ,  C09K8/60 ,  C11D7/42 ,  C12N15/00 ,  C12N5/06 ,  C12N9/48

CPC分类号： C11D3/38636 ,  A23F5/246 ,  A23K20/189 ,  A23L29/06 ,  C09K8/68 ,  C12N9/2494 ,  C12Y302/01078

摘要： The present invention provides an insertion, deletion and/or substitution mutein of wild-type Trichoderma reesei β-mannanase having enhanced thermostability, proteolytic stability, specific activity and/or stability at low pH, a nucleic acid molecule encoding said mannanase mutein, a composition comprising said mannanase mutein; a method for its preparation, and its use for food and feed processing, for coffee extraction and the processing of coffee waste, as a supplement to food and feed, for enzyme aided bleaching of paper pulps, as bleaching and/or desizing agent in textile industry, for oil and gas well stimulation by hydraulic fracturing, as detergent, for removal of biofilms and in delivery systems, or for the processing of renewable resources intended for the production of biological fuels.

摘要翻译： 本发明提供了具有增强的热稳定性，蛋白水解稳定性，比较活性和/或低pH稳定性的野生型里氏木霉β-甘露聚糖酶的插入，缺失和/或取代突变蛋白，编码所述甘露聚糖酶突变蛋白的核酸分子，组合物 包含所述甘露聚糖酶突变蛋白; 其制备方法及其用于食品和饲料加工的咖啡提取和咖啡废弃物的加工，作为食品和饲料的补充，用于纸浆的酶辅助漂白，作为纺织品中的漂白和/或脱浆剂 工业，通过水力压裂的油气井刺激，作为洗涤剂，用于去除生物膜和输送系统，或用于处理用于生产生物燃料的可再生资源。

公开(公告)号：US07846705B2

公开(公告)日：2010-12-07

申请号：US11778690

申请日：2007-07-17

申请人： Oliver Kensch ,  Wayne M. Coco ,  Andreas Scheidig ,  Ute Beister ,  Birgitta Leuthner ,  Nadine Koch ,  Markus Rarbach ,  Ulrich Kettling ,  Ulrich Haupts

发明人： Oliver Kensch ,  Wayne M. Coco ,  Andreas Scheidig ,  Ute Beister ,  Birgitta Leuthner ,  Nadine Koch ,  Markus Rarbach ,  Ulrich Kettling ,  Ulrich Haupts

IPC分类号： C12N9/24

CPC分类号： C11D3/38636 ,  A23F5/246 ,  A23K20/189 ,  A23L29/06 ,  C09K8/68 ,  C12N9/2494 ,  C12Y302/01078

摘要： The present invention provides an insertion, deletion and/or substitution mutein of wild-type Trichoderma reesei β-mannanase having enhanced thermostability, proteolytic stability, specific activity and/or stability at low pH, a nucleic acid molecule encoding said mannanase mutein, a composition comprising said mannanase mutein; a method for its preparation, and its use for food and feed processing, for coffee extraction and the processing of coffee waste, as a supplement to food and feed, for enzyme aided bleaching of paper pulps, as bleaching and/or desizing agent in textile industry, for oil and gas well stimulation by hydraulic fracturing, as detergent, for removal of biofilms and in delivery systems, or for the processing of renewable resources intended for the production of biological fuels.

摘要翻译： 本发明提供了具有增强的热稳定性，蛋白水解稳定性，在低pH下的比活性和/或稳定性的野生型里氏木霉 - 甘露聚糖酶的插入，缺失和/或取代突变蛋白，编码所述甘露聚糖酶突变蛋白的核酸分子， 包含所述甘露聚糖酶突变蛋白的组合物; 其制备方法及其用于食品和饲料加工的咖啡提取和咖啡废弃物的加工，作为食品和饲料的补充，用于纸浆的酶辅助漂白，作为纺织品中的漂白和/或脱浆剂 工业，通过水力压裂的油气井刺激，作为洗涤剂，用于去除生物膜和输送系统，或用于处理用于生产生物燃料的可再生资源。

公开(公告)号：US20090208440A1

公开(公告)日：2009-08-20

申请号：US11969511

申请日：2008-01-04

申请人： Ulrich Haupts ,  Andre Koltermann ,  Andreas Scheidig ,  Christian Votsmeier ,  Ulrich Kettling ,  Oliver Kensch ,  Birgitta Leuthner

发明人： Ulrich Haupts ,  Andre Koltermann ,  Andreas Scheidig ,  Christian Votsmeier ,  Ulrich Kettling ,  Oliver Kensch ,  Birgitta Leuthner

IPC分类号： A61K8/64 ,  C12N9/56 ,  C07H21/04 ,  C12N1/21 ,  C12N15/74

CPC分类号： C12N9/6424 ,  A61K8/64 ,  A61K38/482 ,  A61K38/4826 ,  A61K38/486 ,  A61K38/4873 ,  A61K38/488 ,  A61Q19/00 ,  C12N9/50 ,  C12N9/6472 ,  C12N9/6478 ,  C12N9/6489 ,  C12N15/1034 ,  C12N15/62 ,  C12P21/06 ,  C12Q1/37

摘要： The present invention provides engineered enzymes generated from protein scaffolds combined with Specificity Determining Regions, the production thereof and the use of said engineered enzymes for research, nutritional care, personal care and industrial purposes.

摘要翻译： 本发明提供由与特异性确定区组合的蛋白质支架产生的工程化酶，其生产和所述工程化酶用于研究，营养保健，个人护理和工业目的的用途。

公开(公告)号：US20070298145A1

公开(公告)日：2007-12-27

申请号：US11737057

申请日：2007-04-18

申请人： Andrei MIASNIKOV ,  Vijay Kumar ,  Oliver Kensch ,  Klaus Pellengahr ,  Birgitta Leuthner ,  Ulrich Kettling ,  Andre Koltermann

发明人： Andrei MIASNIKOV ,  Vijay Kumar ,  Oliver Kensch ,  Klaus Pellengahr ,  Birgitta Leuthner ,  Ulrich Kettling ,  Andre Koltermann

IPC分类号： A23K1/165 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N15/55 ,  C12N15/63 ,  C12N15/70 ,  C12N15/74 ,  C12N15/75 ,  C12N9/16

CPC分类号： C12N9/16

摘要： The present invention relates to enzymes and processes. In particular, there is described a host cell transformed or transfected with a nucleic acid encoding a bacterial phytase enzyme and variants thereof.

摘要翻译： 本发明涉及酶和方法。 特别地，描述了用编码细菌植酸酶及其变体的核酸转化或转染的宿主细胞。

公开(公告)号：US08143045B2

公开(公告)日：2012-03-27

申请号：US11696162

申请日：2007-04-03

申请人： Andrei Miasnikov ,  Vijay Kumar ,  Oliver Kensch ,  Klaus Pellangahr ,  Birgitta Leuthner ,  Ulrich Kettling ,  Andre Koltermann

发明人： Andrei Miasnikov ,  Vijay Kumar ,  Oliver Kensch ,  Klaus Pellangahr ,  Birgitta Leuthner ,  Ulrich Kettling ,  Andre Koltermann

IPC分类号： C12N9/16 ,  C12Q1/44

CPC分类号： C12N9/16

摘要： The present invention relates to enzymes and processes. In particular, there is described an isolated polypeptide comprising the amino acid sequence corresponding to Citrobacter freundii phytase or a homologue, a modified form, a functional equivalent or an effective fragment thereof. There is also described a host cell transformed or transfected with a nucleic acid encoding a bacterial phytase enzyme or a modified form as well as the use of such a phytase or modified form in food or animal feed.

摘要翻译： 本发明涉及酶和方法。 特别地，描述了分离的多肽，其包含对应于弗氏柠檬酸杆菌植酸酶的氨基酸序列或其同源物，修饰形式，功能等同物或其有效片段。 还描述了用编码细菌植酸酶或修饰形式的核酸转化或转染的宿主细胞，以及在食物或动物饲料中使用这种植酸酶或修饰形式。

公开(公告)号：US20120301578A1

公开(公告)日：2012-11-29

申请号：US13232588

申请日：2011-09-14

申请人： Andrei Miasnikov ,  Vijay Kumar ,  Oliver Kensch ,  Klaus Pellangahr ,  Birgitta Leuthner ,  Ulrich Kettling ,  Andre Koltermann

发明人： Andrei Miasnikov ,  Vijay Kumar ,  Oliver Kensch ,  Klaus Pellangahr ,  Birgitta Leuthner ,  Ulrich Kettling ,  Andre Koltermann

IPC分类号： C12N9/16 ,  C12N15/63 ,  A23K1/165 ,  C12N1/19 ,  C12N1/20 ,  A23L1/30 ,  C12N15/55 ,  C12N1/21

CPC分类号： C12N9/16

摘要： The present invention relates to enzymes and processes. In particular, there is described an isolated polypeptide comprising the amino acid sequence corresponding to Citrobacter freundii phytase or a homologue, a modified form, a functional equivalent or an effective fragment thereof. There is also described a host cell transformed or transfected with a nucleic acid encoding a bacterial phytase enzyme or a modified form as well as the use of such a phytase or modified form in food or animal feed.

摘要翻译： 本发明涉及酶和方法。 特别地，描述了分离的多肽，其包含对应于弗氏柠檬酸杆菌植酸酶的氨基酸序列或其同源物，修饰形式，功能等同物或其有效片段。 还描述了用编码细菌植酸酶或修饰形式的核酸转化或转染的宿主细胞，以及在食物或动物饲料中使用这种植酸酶或修饰形式。

公开(公告)号：US20090074925A1

公开(公告)日：2009-03-19

申请号：US11696162

申请日：2007-04-03

申请人： Andrei Miasnikov ,  Vijay Kumar ,  Oliver Kensch ,  Klaus Pellangahr ,  Birgitta Leuthner ,  Ulrich Kettling ,  Andre Koltermann

发明人： Andrei Miasnikov ,  Vijay Kumar ,  Oliver Kensch ,  Klaus Pellangahr ,  Birgitta Leuthner ,  Ulrich Kettling ,  Andre Koltermann

IPC分类号： A23L1/48 ,  C12N9/14 ,  C12N15/11 ,  C12N15/00 ,  C12N1/20 ,  C12N1/19 ,  C12P21/04 ,  A23J1/00

CPC分类号： C12N9/16

摘要： The present invention relates to enzymes and processes. In particular, there is described an isolated polypeptide comprising the amino acid sequence corresponding to Citrobacter freundii phytase or a homologue, a modified form, a functional equivalent or an effective fragment thereof. There is also described a host cell transformed or transfected with a nucleic acid encoding a bacterial phytase enzyme or a modified form as well as the use of such a phytase or modified form in food or animal feed.

摘要翻译： 本发明涉及酶和方法。 特别地，描述了分离的多肽，其包含对应于弗氏柠檬酸杆菌植酸酶的氨基酸序列或其同源物，修饰形式，功能等同物或其有效片段。 还描述了用编码细菌植酸酶或修饰形式的核酸转化或转染的宿主细胞，以及在食物或动物饲料中使用这种植酸酶或修饰形式。

公开(公告)号：US20080220498A1

公开(公告)日：2008-09-11

申请号：US11714487

申请日：2007-03-06

申请人： Marguerite A. Cervin ,  Oliver Kensch ,  Ulrich Kettling ,  Birgitta Leuthner ,  Andrei Miasnikov ,  Klaus Pellengahr

发明人： Marguerite A. Cervin ,  Oliver Kensch ,  Ulrich Kettling ,  Birgitta Leuthner ,  Andrei Miasnikov ,  Klaus Pellengahr

IPC分类号： C12N9/14 ,  C12N15/00 ,  C12N15/11 ,  C12N5/06

CPC分类号： C12N9/16 ,  A23K20/189 ,  A23K50/10 ,  A23K50/30 ,  A23K50/75 ,  A23K50/80 ,  C12Y301/03008 ,  C12Y301/03026 ,  C13K1/06 ,  Y02A40/818 ,  Y02E50/17

摘要： The present invention relates to variant phytase enzymes having altered properties.

摘要翻译： 本发明涉及具有改变性质的变体植酸酶。

公开(公告)号：US09273295B2

公开(公告)日：2016-03-01

申请号：US13232588

申请日：2011-09-14

申请人： Andrei Miasnikov ,  Vijay Kumar ,  Oliver Kensch ,  Klaus Pellangahr ,  Birgitta Leuthner ,  Ulrich Kettling ,  Andre Koltermann

发明人： Andrei Miasnikov ,  Vijay Kumar ,  Oliver Kensch ,  Klaus Pellangahr ,  Birgitta Leuthner ,  Ulrich Kettling ,  Andre Koltermann

IPC分类号： C12N9/16

CPC分类号： C12N9/16

摘要： The present invention relates to enzymes and processes. In particular, there is described an isolated polypeptide comprising the amino acid sequence corresponding to Citrobacter freundii phytase or a homologue, a modified form, a functional equivalent or an effective fragment thereof. There is also described a host cell transformed or transfected with a nucleic acid encoding a bacterial phytase enzyme or a modified form as well as the use of such a phytase or modified form in food or animal feed.

摘要翻译： 本发明涉及酶和方法。 特别地，描述了分离的多肽，其包含对应于弗氏柠檬酸杆菌植酸酶的氨基酸序列或其同源物，修饰形式，功能等同物或其有效片段。 还描述了用编码细菌植酸酶或修饰形式的核酸转化或转染的宿主细胞，以及在食物或动物饲料中使用这种植酸酶或修饰形式。

公开(公告)号：US20130136825A2

公开(公告)日：2013-05-30

申请号：US13232588

申请日：2011-09-14

申请人： Andrei Miasnikov ,  Vijay Kumar ,  Oliver Kensch ,  Klaus Pellangahr ,  Birgitta Leuthner ,  Ulrich Kettling ,  Andre Koltermann

发明人： Andrei Miasnikov ,  Vijay Kumar ,  Oliver Kensch ,  Klaus Pellangahr ,  Birgitta Leuthner ,  Ulrich Kettling ,  Andre Koltermann

IPC分类号： C12N9/16 ,  C12N15/63 ,  A23K1/165 ,  C12N1/19 ,  C12N1/20 ,  A23L1/30 ,  C12N15/55 ,  C12N1/21

CPC分类号： C12N9/16

摘要： The present invention relates to enzymes and processes. In particular, there is described an isolated polypeptide comprising the amino acid sequence corresponding to Citrobacter freundii phytase or a homologue, a modified form, a functional equivalent or an effective fragment thereof. There is also described a host cell transformed or transfected with a nucleic acid encoding a bacterial phytase enzyme or a modified form as well as the use of such a phytase or modified form in food or animal feed.