Process for selective oxidation of primary alcohols
    15.
    发明授权
    Process for selective oxidation of primary alcohols 失效
    伯醇选择性氧化的方法

    公开(公告)号:US06518419B1

    公开(公告)日:2003-02-11

    申请号:US09706767

    申请日:2000-11-07

    CPC classification number: C08B15/02 C07C51/285 C07H7/033 C08B31/18

    Abstract: Primary alcohols, especially in carbohydrates, can be selectively oxidized to aldehydes and carboxylic acids in a low-halogen process by using a peracid in the presence of a catalytic amount of a di-tertiary-alkyl nitroxyl (TEMPO) and a catalytic amount of halide. The halide is preferably bromide and the process can be carried out at nearly neutral to moderately alkaline pH (5-11). The peracid can be produced or regenerated by means of hydrogen peroxide or oxygen. The process is advantageous for producing uronic acids and for introducing aldehyde groups which are suitable for crosslinking and derivatization.

    Abstract translation: 通过在催化量的二 - 叔烷基硝酰基(TEMPO)和催化量的卤化物存在下使用过酸,可以将低级醇(特别是碳水化合物)中的伯醇,在低卤素方法中选择性地氧化成醛和羧酸 。 卤化物优选是溴化物,并且该方法可以在接近中性至中等碱性pH(5-11)下进行。 过酸可以通过过氧化氢或氧气生产或再生。 该方法有利于生产糖醛酸和用于引入适于交联和衍生化的醛基。

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