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公开(公告)号：US20170271038A1
公开(公告)日：2017-09-21
申请号：US15532089
申请日：2015-12-04
Applicant: General Electric Company , Medi-Physics Inc.
Inventor： Matthew David Butts , Charles E. Shanks
CPC classification number: G21G4/06 , B29C39/003 , B29K2063/00 , B29K2505/08 , G21G1/001 , G21G1/02 , G21G1/06 , G21G4/08 , G21G2001/0094
Abstract: An equatorial anthropic radiation source and a method of making an equatorial anthropic radiation source are described. The radiation source is useful in diagnostic imaging applications in healthcare or other industries (e.g. computerized three-dimensional segmental imaging; Crompton scattering imaging techniques; radiation detector check and calibration, in particular CdZnTe detectors commonly used in medical imaging).
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公开(公告)号：US09324466B2
公开(公告)日：2016-04-26
申请号：US14651447
申请日：2013-12-26
Applicant: Medi-Physics Inc.
Inventor： Kevin Helle , Jay Reed , Robert F Chisholm
Abstract: The present invention provides a radiation-shielding container for a radiopharmaceutical that allows or a product fluid to be dispensed from a base component thereof.
Abstract translation: 本发明提供了一种用于放射性药物的辐射屏蔽容器，其允许或从其基础部件分配产品流体。
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13.发明授权Hyperpolarized gas containers,solenoids, transport and storage devices and associated transport and storage methods 失效超极化气体容器，螺线管，运输和存储设备以及相关的运输和储存方法公开(公告)号：US6430939B2
公开(公告)日：2002-08-13
申请号：US84672001
申请日：2001-05-01
Applicant: MEDI PHYSICS INC
Inventor： HASSON KENTON C , ZOLLINGER GERI T K , ZOLLINGER DAVID L , BOGORAD PAUL L , WHEELER BRADLEY A
CPC classification number: G01R33/282 , A61K49/1815 , F17C1/00 , F17C3/00 , F17C13/002 , F17C13/005 , F17C2201/0128 , F17C2201/0176 , F17C2201/058 , F17C2203/0604 , F17C2203/0607 , F17C2203/0629 , F17C2203/0636 , F17C2203/0646 , F17C2203/066 , F17C2203/0685 , F17C2203/0697 , F17C2205/0134 , F17C2205/0323 , F17C2205/035 , F17C2205/0352 , F17C2205/0382 , F17C2221/07 , F17C2223/0123 , F17C2223/035 , F17C2225/0123 , F17C2225/035 , F17C2227/041 , F17C2227/044 , F17C2250/032 , F17C2250/0404 , F17C2250/0491 , F17C2260/012 , F17C2260/026 , F17C2260/03 , F17C2270/02 , F17C2270/0536 , Y10S62/914
Abstract: A compact portable transport unit for shipping hyperpolarized noble gases and shielding same from electromagnetic interference and/or external magnetic fields includes a means for shifting the resonance frequency of the hyperpolarized gas outside the bandwidth of typical frequencies associated with prevalent time-dependent fields produced by electrical sources. Preferably the transport unit includes a magnetic holding field which is generated from a solenoid in the transport unit. The solenoid includes a plurality of coil segments and is sized and configured to receive the gas chamber of a container. The gas container is configured with a valve, a spherical body, and an extending capillary stem between the valve and the body. The gas container or hyperpolarized product container can also be formed as a resilient bag. The distribution method includes positioning a multi-bolus container within the transport unit to shield it and transporting same to a second site remote from the first site and subsequently dispensing into smaller patient sized formulations which can be transported (shielded) in another transport unit to yet another site.
Abstract translation: 用于运输超极化惰性气体并将其与电磁干扰和/或外部磁场屏蔽的紧凑便携式运输单元包括用于将超极化气体的共振频率移动到与由电气产生的流行的时间依赖场相关的典型频率的带宽之外的装置 来源。 优选地，传送单元包括从传送单元中的螺线管产生的磁保持场。 螺线管包括多个线圈段，其尺寸和构造用于容纳容器的气室。 气体容器在阀和主体之间配置有阀，球体和延伸的毛细管杆。 气体容器或超极化产品容器也可以形成为弹性袋。 分配方法包括将多次推注容器定位在运输单元内以对其进行屏蔽并将其运送到远离第一部位的第二部位，并随后分配到可在另一运输单元中运输（屏蔽）的较小的患者尺寸的配方中 另一个网站。
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公开(公告)号：US3749556A
公开(公告)日：1973-07-31
申请号：US3749556D
申请日：1971-08-19
Applicant: MEDI PHYSICS INC
Inventor： BARAK M , WINCHELL H
CPC classification number: A61K51/1282 , A61K2123/00 , G01N30/52 , G01N30/6034
Abstract: A KIT READILY ASSEMBLED INTO ESSENTIALLY A PACKED CHROMATOGRAPHIC COLUMN FOR GENERATING TECHNETIUM-99M LABELED PHARMACEUTICALS IN A SIMPLE TWO-STEP PROCESS. TECHNETIUM-99M PERTECHNETATE IN A FIRST STEP IS ISOLATED AND ITS VALENCE STATE REDUCED BY ADSORPTION UPON A REDUCING AGENT. THEN THE REDUCED TECHNETIUM-99M IN A SECOND STEP IS ELUTED FROM THE REDUCING AGENT BY COMBINATION WITH AN IMMEDIATELY LABELED BIOLOGICAL COMPOUND, THE ELUANT PH IS ADJUSTED AND BUFFERED TO PHYSIOLOGICAL LEVELS AND BENIGN CATIONS ARE SUBSTITUTED FOR UNCOMBINED REDUCING AGENT AND ISOTOPE IONS. A NEW TECHNETIUM-99M LABELED RADIOPHARMACEUTICAL USEFUL IN LIVER IMAGING IS PRODUCED BY INTERACTION WITH THE COLUMN PACKING IN ONE SPECIFIC ASPECT OF THE PROCEDURE.
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Patent Agency Ranking
公开(公告)号：US09726591B2
公开(公告)日：2017-08-08
申请号：US14655259
申请日：2013-12-26
Applicant: MEDI-PHYSICS, INC.
Inventor： Kevin M Helle , Michael T Schneider
CPC classification number: G01N15/082 , A61L2/022 , B01D65/102 , G01N2015/084
Abstract: A dual-filter dual-integrity test conduit assembly allows for in-situ testing of both filters with separate, duplicate systems for membrane integrity so that if the first tester filter fails, the second filter may be tested with a different, but identical method with its own gauges and nitrogen supply so as to further isolate malfunctions of the filter integrity test equipment as a cause for erroneous batch failures.
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公开(公告)号：US20150352013A1
公开(公告)日：2015-12-10
申请号：US14655507
申请日：2013-12-26
Applicant: MEDI-PHYSICS, INC.
Inventor： Kevin M HELLE
CPC classification number: A61J1/201 , A61J1/20 , A61J1/2075 , A61M39/0208 , A61M2039/0036 , B65B3/003
Abstract: Asceptic transfer through a needle penetrating a septum is accomplished by inserting an elongate inner tube through the needle and delivering a product fluid through the inner tube. Inner tube is desirably made from a polymer such as PTFE and product fluid does not contact the needle.
Abstract translation: 通过穿过隔膜的针的透过性转移是通过将细长的内管插入穿过针头并将产品流体输送通过内管来实现的。 内管希望由诸如PTFE的聚合物制成，并且产品流体不接触针。
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公开(公告)号：US20150325321A1
公开(公告)日：2015-11-12
申请号：US14651447
申请日：2013-12-26
Applicant: Medi-Physics, Inc.
Inventor： Kevin M. HELLE , Jay C. REED , Robert F. CHISHOLM
Abstract: The present invention provides a radiation-shielding container for a radiopharmaceutical that allows or a product fluid to be dispensed from a base component thereof.
Abstract translation: 本发明提供了一种用于放射性药物的辐射屏蔽容器，其允许或从其基础部件分配产品流体。
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公开(公告)号：US3902849A
公开(公告)日：1975-09-02
申请号：US38379773
申请日：1973-07-30
Applicant: MEDI PHYSICS INC
Inventor： BARAK MORTON , WINCHELL HARRY W
CPC classification number: G01N30/6091 , A61K51/1282 , A61K2123/00 , G01N30/52 , G01N30/603 , G01N30/6034
Abstract: A chromatographic column for generating technetium-99m isotopes and technetium-99m labeled pharmaceuticals in a simple two-step process. Technetium-99m pertechnetate in a first step is isolated by adsorption upon an adsorbent packing. Then the technetium-99m in a second step is eluted from the packing, either with an immediately labeled biological compound to form a radiopharmaceutical, or by a controlled volume of eluant to produce a 99m-technetium-bearing eluate of a desired specific concentration.
Abstract translation: 一种用于以简单的两步法生成锝-99m同位素和锝-99m标记药物的色谱柱。 锝-99m高锝酸盐在第一步通过吸附填料分离。 然后第二步中的锝-99m从包装中用立即标记的生物化合物洗脱以形成放射性药物，或通过受控体积的洗脱液洗脱，以产生具有所需特定浓度的99m-含锝的洗脱液。
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公开(公告)号：US3875299A
公开(公告)日：1975-04-01
申请号：US25073872
申请日：1972-05-05
Applicant: MEDI PHYSICS INC
Inventor： WINCHELL HARRY S , BARAK MORTON , VAN FLEET III PARMER
CPC classification number: A61K51/1217 , A61K2123/00
Abstract: An improved 99m- technetium labeled tin(II) colloid, size stabilized for reticuloendothelial organ imaging without the use of macromolecular stabilizers and a packaged tin base reagent and improved method for making it.
Abstract translation: 改进的99m-锝标记的锡（II）胶体，尺寸稳定的网状内皮细胞成像，不使用大分子稳定剂和包装的锡碱试剂和改进的制备方法。
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