中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

350 records (took 0.026 seconds)

    COMPOSITIONS AND METHODS FOR ASSAY MEASUREMENTS
    11.
    发明公开
    COMPOSITIONS AND METHODS FOR ASSAY MEASUREMENTS 审中-公开

    公开(公告)号：US20230279290A1

    公开(公告)日：2023-09-07

    申请号：US18145735

    申请日：2022-12-22

    Applicant: Meso Scale Technologies, LLC.

    Inventor： John Kenten ,  John Pettersson ,  George Sigal ,  Alexander K. Tucker-Schwartz

    IPC: C09K11/02 ,  C12Q1/6816

    CPC classification number: C09K11/02 ,  C12Q1/6816

    Abstract: The disclosure relates to novel compositions comprising an electrochemiluminescence (ECL) co-reactant. In embodiments, the composition further comprises an ionic component, a surfactant, or combination thereof. In embodiments, the ECL co-reactant is triethanolamine (TEA), tert-butyldiethanolamine (tBDEA), methyldibutylethanolamine (MDEA), 3-[Bis-(2-hydroxy-ethyl)-amino]-propane-1-sulfonic acid (DEA-PS), or a combination thereof. Methods of using the compositions and kits comprising the compositions are also provided herein, including methods using ECL-labeled oligonucleotide probes having quenching moieties.

    DEVICE HOUSING WITH LIGHTING
    13.
    发明申请
    DEVICE HOUSING WITH LIGHTING 有权

    公开(公告)号：US20230070700A1

    公开(公告)日：2023-03-09

    申请号：US17986182

    申请日：2022-11-14

    Applicant: Meso Scale Technologies, LLC.

    Inventor： Cecilia Zimmerman ,  Jules VanDersarl

    IPC: F21V8/00 ,  F21V3/00

    Abstract: The application is directed to a device housing. The device housing includes a first light device, the first light device including a first electrical supply configured to provide an electrical signal to a first light emitting diode (LED), the first LED separated from a first surface of a diffuser film by a space, wherein the diffuser film includes a second surface, opposite the first surface, the second surface configured to contact a first light pipe.

    METHODS AND KITS FOR DETECTING AUTOIMMUNE DISEASES
    15.
    发明申请
    METHODS AND KITS FOR DETECTING AUTOIMMUNE DISEASES 有权

    公开(公告)号：US20230021837A1

    公开(公告)日：2023-01-26

    申请号：US17779900

    申请日：2020-11-25

    Applicant: MESO SCALE TECHNOLOGIES, LLC.

    Inventor： Anu MATHEW ,  Mingyue WANG ,  Christopher CAMPBELL ,  Katarzyna HAYNESWORTH ,  Nikhil PADMANABHAN ,  Martin STENGELIN ,  Paridhi GUPTA ,  Rashmi SRIRAM

    IPC: G01N33/564 ,  G01N33/543

    Abstract: The invention relates to assay methods and kits for assessing autoimmune diseases in a human subject. In embodiments, the present disclosure provides assay methods and kits for diagnosing a subject with or predicting that a subject will develop Type 1 diabetes. In embodiments, the present disclosure provides assay methods and kits for assessing responsiveness of a subject having Type 1 diabetes to treatment with alefacept. In embodiments, the present disclosure provides assay methods and kits for diagnosing a subject with systemic lupus erythematosus. In embodiments, the present disclosure provides assay methods and kits for determining if a subject is at risk of a systemic lupus erythematosus flare. In embodiments, the present disclosure provides assay methods and kits for diagnosing a subject with celiac disease.

    MULTI-PLEX ASSAY PLATES AND METHODS OF MAKING
    17.
    发明申请
    MULTI-PLEX ASSAY PLATES AND METHODS OF MAKING 有权

    公开(公告)号：US20220341923A1

    公开(公告)日：2022-10-27

    申请号：US17728292

    申请日：2022-04-25

    Applicant: Meso Scale Technologies, LLC.

    Inventor： John H. KENTEN ,  Galina NIKOLENKO

    IPC: G01N33/543 ,  G01N21/76 ,  G01N33/53 ,  G01N33/569 ,  G01N33/58

    Abstract: Described herein is a method of preparing a bifunctional assay surface. In particular, a method is provided for preparing an assay surface that includes a primary reagent and a secondary reagent. In one aspect, the primary and secondary reagents are immobilized on the assay surface by different surface chemistries. In one aspect, a method is provided for preparing an assay surface that includes a proteinaceous primary reagent and a thiol-containing secondary reagent. In one aspect, a method is provided for preparing an assay surface that includes a capture-target hybrid and a thiol-containing secondary reagent.

    ASSAY SYSTEM CALIBRATION SYSTEMS AND METHODS
    20.
    发明申请
    ASSAY SYSTEM CALIBRATION SYSTEMS AND METHODS 有权

    公开(公告)号：US20220221449A1

    公开(公告)日：2022-07-14

    申请号：US17572280

    申请日：2022-01-10

    Applicant: MESO SCALE TECHNOLOGIES, LLC.

    Inventor： John JOERN ,  George SIGAL

    IPC: G01N33/543 ,  G06F17/18

    Abstract: Systems and methods for calibrating sample assays are provided. Systems may include assay devices and components for carrying out calibration and sample assays. Systems may further include processing components and storage units configured for receiving calibration information, determining calibration models and parameters, and applying calibration parameters to sample data. Systems may further include components for operating in a networked environment. Methods may include techniques and processes for carrying out calibration and sample assays, determining calibration models and parameters, and applying calibration parameters to sample data.

Patent Agency Ranking