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公开(公告)号：US4309713A
公开(公告)日：1982-01-05
申请号：US52277
申请日：1979-06-26
Applicant: Fumiaki Shinozaki , Tomizo Namiki , Masao Kitajima , Tomoaki Ikeda , Yuzo Mizobuchi
Inventor： Fumiaki Shinozaki , Tomizo Namiki , Masao Kitajima , Tomoaki Ikeda , Yuzo Mizobuchi
CPC classification number: G11B7/2575 , G11B7/252 , G11B7/2542 , G11B2007/2431 , G11B2007/24312 , G11B2007/24324 , G11B2007/24326 , G11B7/2535 , Y10S430/162 , Y10T428/31699
Abstract: A thermal recording element comprising a support, a recording layer formed thereon and a chlorinated polyolefin layer formed on said recording layer.
Abstract translation: 一种热敏记录元件，包括载体，形成在其上的记录层和形成在所述记录层上的氯化聚烯烃层。
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公开(公告)号：US4292272A
公开(公告)日：1981-09-29
申请号：US157737
申请日：1980-06-09
Applicant: Masao Kitajima , Fuminori Arai , Asaji Kondo
Inventor： Masao Kitajima , Fuminori Arai , Asaji Kondo
CPC classification number: G01N33/525
Abstract: A multilayer analysis sheet for analyzing liquid samples is described, comprising, in sequence, a light transmitting hydrophobic support having on one side thereof at least one layer containing at least one reagent in a binder and a liquid sample spreading layer made of fabric, which layers are laminated to form an integral unit together with the support, wherein said fabric has the ability to supply a liquid sample placed on the surface thereof to the reagent-containing layer at a substantially constant volume per unit area, which ability is conferred upon the fabric by rendering it hydrophilic; the multilayer analysis sheet can be economically manufactured without variations in quality, and improves the spreading capability of liquid samples.
Abstract translation: 描述了用于分析液体样品的多层分析片，其中依次包括透光性疏水性支持体，其透光性疏水性支持体的一面上具有至少一层含有粘合剂中的至少一种试剂和由织物构成的液体样品扩散层， 层叠以与支撑体一起形成整体单元，其中所述织物具有以每单位面积基本上恒定的体积供应将其表面上的液体样品供应到含有试剂的层的能力，该能力被赋予织物 通过使其亲水; 可以经济地制造多层分析片而不产生质量变化，并提高液体样品的铺展能力。
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公开(公告)号：US3951851A
公开(公告)日：1976-04-20
申请号：US364478
申请日：1973-05-29
Applicant: Masao Kitajima , Asaji Kondo , Fuminori Arai
Inventor： Masao Kitajima , Asaji Kondo , Fuminori Arai
CPC classification number: A61K9/5047 , A61K31/60 , A61K9/5089 , Y10T428/2989
Abstract: Process of producing aspirin-containing capsules which comprises (1) dispersing aspirin particles in a solution of a cellulose derivative in an organic solvent partially miscible with water; (2) adding the dispersion to an encapsulation medium comprising water containing organic solvent(s) partially miscible with water with or without aspirin; (3) stirring the mixture to form a fine dispersion of the aspirin; and (4) evaporating off the organic solvent to deposit the cellulose derivative around the aspirin particles.
Abstract translation: 制备含阿司匹林胶囊的方法，其包括（1）将阿司匹林颗粒分散在纤维素衍生物在与水部分混溶的有机溶剂中的溶液中; （2）将分散体加入到包含含有有机溶剂的水的包封介质中，所述有机溶剂与或不与阿斯匹林部分混溶; （3）搅拌混合物形成阿司匹林的精细分散体; 和（4）蒸发掉有机溶剂以将纤维素衍生物沉积在阿司匹林颗粒周围。
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公开(公告)号：US06220453B1
公开(公告)日：2001-04-24
申请号：US09287425
申请日：1999-04-07
Applicant: Masao Kitajima , Sigeru Tezuka , Yasuo Washizawa , Kenichiro Yazawa
Inventor： Masao Kitajima , Sigeru Tezuka , Yasuo Washizawa , Kenichiro Yazawa
IPC: B01D3500
CPC classification number: G01N1/4077 , A61M1/3633 , B01D19/0031 , B01D61/18 , B01D61/20
Abstract: This invention provides a blood filter unit capable of obtaining a necessary volume of a plasma or serum sample from blood to be assayed easily at any place, which comprises a blood filtering material and a holder accommodating the blood filtering material and having a nozzle for sucking blood and a filtrate outlet, and the inside of the holder being kept reduced pressure conditions.
Abstract translation: 本发明提供一种血液过滤器单元，其能够在任何地方容易地从血液中获得需要测定血液的血浆或血清样品的必需体积，该血液或血清样品包括血液过滤材料和容纳血液过滤材料的保持器，并具有用于吸入血液的喷嘴 和滤液出口，并且保持器的内部保持减压条件。
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公开(公告)号：US5979669A
公开(公告)日：1999-11-09
申请号：US784481
申请日：1997-01-17
Applicant: Masao Kitajima , Kenichiro Yazawa , Shigeru Tezuka , Fumio Sugaya , Akemi Higo , Kiyotaka Fujiwara
Inventor： Masao Kitajima , Kenichiro Yazawa , Shigeru Tezuka , Fumio Sugaya , Akemi Higo , Kiyotaka Fujiwara
IPC: G01N33/48 , B01D39/20 , B01D61/18 , B01D61/20 , B01D69/12 , G01N1/10 , G01N1/28 , G01N33/49 , B01D29/05 , B01D29/56 , B01D29/92
CPC classification number: B01D39/2017 , B01D61/18 , B01D61/20 , B01D69/12 , G01N33/491
Abstract: A blood filter unit having a blood filter holder containing a blood filtering material of a glass fiber filter and a microporous membrane is described. The holder has a blood inlet and a filtrate outlet, and accommodates the blood filtering material so that the microporous membrane is located on the filtrate outlet side and has a space between the blood filtering material and the filtrate outlet. The holder provides means for preventing adhesion of the blood filtering material on the filtrate outlet side. The inventive blood filter unit allows separation of a desired volume of plasma or serum for analysis without interference by the hematocrit value of the blood.
Abstract translation: 描述了具有含有玻璃纤维过滤器的血液过滤材料和微孔膜的血液过滤器保持器的血液过滤器单元。 保持器具有血液入口和滤液出口，并且容纳血液过滤材料，使得微孔膜位于滤液出口侧，并且在血液过滤材料和滤液出口之间具有空间。 保持器提供用于防止血液过滤材料在滤液出口侧粘附的装置。 本发明的血液过滤器单元允许分离所需体积的血浆或血清用于分析，而不受血液的血细胞比容值的干扰。
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Patent Agency Ranking
公开(公告)号：US5460777A
公开(公告)日：1995-10-24
申请号：US29799
申请日：1993-03-11
Applicant: Masao Kitajima , Masashi Ogawa , Osamu Seshimoto
Inventor： Masao Kitajima , Masashi Ogawa , Osamu Seshimoto
IPC: G01N33/49
CPC classification number: G01N33/491
Abstract: An analytical element for whole blood which comprises a blood cell-separating layer having a volume smaller than the upper limit of the diffused volume of a whole blood sample having a hematocrit value of 70% provided on a porous layer, and a method of measuring an analyte which comprises spotting a whole blood sample onto the above analytical element removing the blood cell-separating layer after blood plasma portion of the sample is diffused into the porous layer, supplying a fixed amount of measuring reagent solution having a diffused area smaller than the diffused area of the blood plasma to measure the analyte. According to the invention, the analytical error caused by scattering of hematocrit values is removed, and analysis can be conducted in a high accuracy.
Abstract translation: 一种全血分析元件，其特征在于，具有比多孔层上具有血细胞比容值为70％的全血样品的扩散体积的上限容积小的血细胞分离层， 分析物，其包括将全血样品点样到所述分析元件上，在样品的血浆部分扩散到多孔层中之后去除血细胞分离层，提供固定量的测量试剂溶液，其扩散面积小于扩散区 血浆的面积来测量分析物。 根据本发明，消除了血细胞比容值散射引起的分析误差，可以高精度地进行分析。
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公开(公告)号：US4612290A
公开(公告)日：1986-09-16
申请号：US542569
申请日：1983-10-19
Applicant: Kenichiro Yazawa , Osamu Seshimoto , Masao Kitajima , Asaji Kondo
Inventor： Kenichiro Yazawa , Osamu Seshimoto , Masao Kitajima , Asaji Kondo
CPC classification number: G01N33/728 , Y10T436/146666 , Y10T436/255
Abstract: A method for quantitative determination of bilirubin is disclosed. The method comprises bringing a bilirubin-containing aqueous liquid sample into contact with a hydrophobic bilirubin extracting composition containing a hydrophobic amine capable of extracting bilirubin. The amine extracts the bilirubin in said aqueous liquid sample. Photometry is then used to determine the concentration of bilirubin extracted with the bilirubin extracting composition. A device for use in this method is also disclosed. The device has a layer containing a hydrophobic bilirubin extracting composition containing a hydrophobic amine capable of extracting bilirubin.
Abstract translation: 公开了一种定量测定胆红素的方法。 该方法包括使含胆红素的含水液体样品与含有能够提取胆红素的疏水性胺的疏水性胆红素提取组合物接触。 胺提取所述含水液体样品中的胆红素。 然后使用光度测定法测定用胆红素提取组合物提取的胆红素的浓度。 还公开了一种用于该方法的装置。 该装置具有包含含有能够提取胆红素的疏水性胺的疏水性胆红素提取组合物的层。
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公开(公告)号：US4578245A
公开(公告)日：1986-03-25
申请号：US534085
申请日：1983-09-20
Applicant: Fuminori Arai , Yoshio Inagaki , Masao Kitajima
Inventor： Fuminori Arai , Yoshio Inagaki , Masao Kitajima
CPC classification number: C12Q1/28 , G01N31/22 , G01N33/525 , C12Q2326/00 , C12Q2326/96
Abstract: A multilayer analytical element comprising a water-impermeable, light-transmissive support, a reagent layer containing a color forming reagent composition for detection of hydrogen peroxide including at least combination of a chromogen and a coupler (a color indicator composition), and peroxidase, which produces a detectable change in the presence of peroxidase and hydrogen peroxide, and a porous spreading layer, which are superposed in this order,in which said chromogen is a 1,2,3-tri-substituted compound of 4-amino-3-pyrazolin-5-one having solubility in water at 25.degree. C. of lower than that of 4-amino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one.
Abstract translation: 一种多层分析元件，包括不透水的透光性载体，含有用于检测至少包括色原和成色剂的组合物的过氧化氢的成色剂组合物（颜色指示剂组合物）的试剂层和过氧化物酶， 在过氧化物酶和过氧化氢的存在下产生可检测的变化，以及以该顺序重叠的多孔扩散层，其中所述色原是4-氨基-3-吡唑啉的1,2,3-三取代化合物 -5-酮在25℃下在水中的溶解度低于4-氨基-2,3-二甲基-1-苯基-3-吡唑啉-5-酮的溶解度。
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公开(公告)号：US4396700A
公开(公告)日：1983-08-02
申请号：US331742
申请日：1981-12-17
Applicant: Masao Kitajima , Hiromichi Tachikawa , Fumiaki Shinozaki , Tomoaki Ikeda
Inventor： Masao Kitajima , Hiromichi Tachikawa , Fumiaki Shinozaki , Tomoaki Ikeda
CPC classification number: G03F7/346
Abstract: A process for forming an image is disclosed wherein a photosensitive image-forming material comprising a diazonium compound or an azide compound is exposed and developed by a peeling development method wherein a development carrier sheet having thereon a layer of an adhesive composition is adhered to the image-forming material, before or after exposure, and, after exposure, peeled from the image-forming material whereby the exposed areas of the photosensitive layer are adhered to the carrier sheet thereby forming a relief image, and the unexposed areas remaining adhered to the support also forming a relief image.
Abstract translation: 公开了一种用于形成图像的方法，其中包含重氮化合物或叠氮化合物的感光成像材料通过剥离显影方法曝光和显影，其中其上具有粘合剂组合物层的显影载体片材粘附到图像上 在曝光之前或之后，曝光后，从图像形成材料剥离，由此感光层的曝光区域粘附到载体片上，从而形成浮雕图像，并且未曝光区域保持粘附到支撑体 也形成浮雕形象。
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公开(公告)号：US4356149A
公开(公告)日：1982-10-26
申请号：US165444
申请日：1980-07-02
Applicant: Masao Kitajima , Fuminori Arai , Asaji Kondo
Inventor： Masao Kitajima , Fuminori Arai , Asaji Kondo
CPC classification number: C12Q1/58 , G01N33/526 , Y10S435/805
Abstract: A multi-layer chemical analytical material comprising a support, a reagent layer on the support and a spreading layer on the reagent layer wherein the reagent layer is composed of a hydrophilic binder and fine hydrophobic particles dispersed in the hydrophilic binder, said hydrophobic particles containing a reagent capable of directly or indirectly reacting with the component being analyzed to produce a color change.
Abstract translation: 一种多层化学分析材料，包括载体，载体上的试剂层和试剂层上的扩散层，其中试剂层由亲水性粘合剂和分散在亲水性粘合剂中的细疏水性颗粒构成，所述疏水性颗粒含有 能够直接或间接地与被分析的组分反应以产生颜色变化的试剂。
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