METHODS FOR CELL GENOTYPING
    11.
    发明申请
    METHODS FOR CELL GENOTYPING 审中-公开
    细胞基因分析方法

    公开(公告)号:US20110033862A1

    公开(公告)日:2011-02-10

    申请号:US12918445

    申请日:2009-02-19

    CPC classification number: C12Q1/6876 C12Q2600/156 C12Q2600/16 C12Q2600/172

    Abstract: Methods for cell genotyping are disclosed herein. A method for determining the genomic data of one or a small number of cells, or from fragmentary DNA, where a limited quantity of genetic data is available may include adding one or more targeted primers to a whole genome amplification of a cell, increasing the accuracy with which key alleles are measured in the context of a whole genome amplification. The genetic material from a single cell may be divided into fractions, each of which may be separately genotyped, allowing the reconstruction of the cells haplotype. The genetic material from a single cell may be divided into fractions, each of which may be separately genotyped, and the distribution of the various alleles in the different fractions may be used to determine the ploidy state of one or a plurality of chromosomes in the cell.

    Abstract translation: 本文公开了细胞基因分型的方法。 用于确定有限数量的遗传数据可用的一个或少数细胞或来自片段DNA的基因组数据的方法可包括向细胞的全基因组扩增添加一种或多种靶向引物,增加细胞的准确度 在全基因组扩增的情况下测量关键等位基因。 来自单个细胞的遗传物质可以被分成各自的部分,每一个可以分开进行基因分型,允许重建细胞单元型。 来自单个细胞的遗传物质可以分成各自的部分,每个可以分别进行基因分型,并且可以使用不同级分中各种等位基因的分布来确定细胞中一条或多条染色体的倍性状态 。

    Wide-lane pseudorange measurements using FM signals
    13.
    发明授权
    Wide-lane pseudorange measurements using FM signals 有权
    使用FM信号的宽行距伪距测量

    公开(公告)号:US07498873B2

    公开(公告)日:2009-03-03

    申请号:US11554765

    申请日:2006-10-31

    CPC classification number: G01S11/02 G01S5/0263 G01S5/12

    Abstract: Apparatus having corresponding methods and computer-readable media comprises a receiver to receive a wireless stereo frequency-modulation (FM) signal comprising a plurality of spectral signal components including a first tone and one or more frequency bands; one or more tone generators each to generate a respective second tone based on a respective one of the frequency bands; a plurality of phase circuits each to measure a phase of a respective one of the first and second tones; and a difference element to determine a phase difference between two of the phases.

    Abstract translation: 具有相应方法和计算机可读介质的装置包括:接收器,用于接收包括包括第一音调和一个或多个频带的多个频谱信号分量的无线立体声调频(FM)信号; 一个或多个音调发生器,每个音调发生器基于相应的一个频带产生相应的第二音调; 多个相位电路,各自测量第一和第二音调中的相应一个的相位; 以及差分元件,以确定两相之间的相位差。

    Rapid acquisition and correlation of synchronization codes for mobile devices with limited memory and computational power
    16.
    发明申请
    Rapid acquisition and correlation of synchronization codes for mobile devices with limited memory and computational power 失效
    有限的存储器和计算能力的移动设备的同步码的快速采集和相关性

    公开(公告)号:US20060061691A1

    公开(公告)日:2006-03-23

    申请号:US10946070

    申请日:2004-09-22

    Abstract: The present invention provides a method, system, and apparatus for rapidly acquiring and correlating synchronization codes for a mobile receiver used for position determination purposes. The receiver uses a processing unit to perform the correlation functions. The processing unit first computes, for each segment interval of the received signal, the phase offset of that interval. Each interval is appropriately adjusted to account for the computed phase offset. The processing unit then accumulates the phase-adjusted segment intervals, and may down-convert the accumulated signal to a baseband format from an intermediate frequency. The processing unit then correlates the accumulated signal with a reference signal to produce a correlation peak, from which the time delay of a synchronization code within the interval can be calculated. Ultimately, the receiver's position can be determined based on the calculated time delay.

    Abstract translation: 本发明提供一种用于快速获取和关联用于位置确定目的的移动接收机的同步码的方法,系统和装置。 接收机使用处理单元执行相关功能。 对于接收信号的每个段间隔,处理单元首先计算该间隔的相位偏移。 适当调整每个间隔以计算相位偏移。 处理单元然后累积相位调整的段间隔,并且可以将累积信号从中频降频转换为基带格式。 然后,处理单元将累加的信号与参考信号相关联,以产生相关峰值,从而可以计算间隔内的同步码的时间延迟。 最终,接收机的位置可以基于计算的时间延迟来确定。

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