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54 条记录 (耗时 0.06 秒)

    Process for the preparation of dihydropyrrole derivatives
    14.
    发明授权
    Process for the preparation of dihydropyrrole derivatives 有权
    二氢吡咯衍生物的制备方法

    公开(公告)号：US09233920B2

    公开(公告)日：2016-01-12

    申请号：US13703630

    申请日：2011-06-14

    申请人： Myriem El Qacemi ,  Helmars Smits ,  Jerome Yves Cassayre ,  Nicholas Phillip Mulholland ,  Peter Renold ,  Edouard Godineau ,  Thomas Pitterna

    发明人： Myriem El Qacemi ,  Helmars Smits ,  Jerome Yves Cassayre ,  Nicholas Phillip Mulholland ,  Peter Renold ,  Edouard Godineau ,  Thomas Pitterna

    IPC分类号： C07D207/46 ,  C07D207/20 ,  C07D401/04 ,  C07D413/12 ,  C07D413/14 ,  C07D417/14 ,  A01N43/36

    CPC分类号： C07D207/46 ,  A01N43/36 ,  C07D207/20 ,  C07D401/04 ,  C07D413/12 ,  C07D413/14 ,  C07D417/14

    摘要： The present invention provides stereoselective processes for the preparation of compounds of formula (I) wherein P is phenyl, naphthyl, a 6-membered heteroaryl group containing one or two nitrogen atoms as ring members, or a 10-membered bicyclic heteroaryl group containing one or two nitrogen atoms as ring members, and wherein the phenyl, naphthyl and heteroaryl groups are optionally substituted; R1 is chlorodifluoromethyl or trifluoromethyl; R2 is optionally substituted aryl or optionally substituted heteroaryl; n is 0 or 1; including the process comprising (a-i) reacting a compound of formula II wherein P, R1 and R2 are as defined for the compound of formula I; with nitromethane in the presence a chiral catalyst to give a compound of formula III Wherein P, R1 and R2 are as defined for the compound of formula I; and (a-ii) reductively cyclizing the compound of formula III to give the compound of formula I. The invention also provides intermediates useful for processes for the synthesis of compounds of formula (I).

    摘要翻译： 本发明提供了制备式（I）化合物的立体选择性方法，其中P是苯基，萘基，含有一个或两个氮原子作为环成员的6元杂芳基或含有一个或多个氮原子的10元双环杂芳基 两个氮原子作为环成员，并且其中苯基，萘基和杂芳基任选被取代; R1是氯二氟甲基或三氟甲基; R2是任选取代的芳基或任选取代的杂芳基; n为0或1; 包括（a-i）使式II化合物与式Ⅰ化合物反应的方法，其中P，R 1和R 2如对式I化合物所定义; 在硝基甲烷中存在手性催化剂，得到式III化合物，其中P，R 1和R 2如式I化合物所定义; 和（a-ii）将式III化合物还原性环化得到式I化合物。本发明还提供了可用于合成式（I）化合物的方法的中间体。

    ISOTHIAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS
    17.
    发明申请
    ISOTHIAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS 有权
    异噻唑衍生物作为杀虫剂化合物

    公开(公告)号：US20140378415A1

    公开(公告)日：2014-12-25

    申请号：US14344123

    申请日：2012-08-27

    申请人： Jerome Yves Cassayre ,  Myriem El Qacemi

    发明人： Jerome Yves Cassayre ,  Myriem El Qacemi

    IPC分类号： A01N43/90 ,  A01N43/00 ,  A01N43/80 ,  A01N51/00

    CPC分类号： A01N43/90 ,  A01N43/00 ,  A01N43/80 ,  A01N51/00 ,  C07C323/22 ,  C07C323/56 ,  C07C327/22 ,  C07C327/32 ,  C07D249/08 ,  C07D275/02 ,  C07D291/04 ,  C07D331/04 ,  C07D417/10 ,  C07D417/12

    摘要： The present invention provides compounds of formula (I) wherein P is P0, heterocyclyl or heterocyclyl substituted by one to five Z formula (II); Y1, Y2, Y3 and Y4 are independently of each other C—H, C—R5, or nitrogen; G1 is oxygen or sulfur; X4 is C1-C8 haloalkyl; R4 is aryl or aryl substituted by one to five R9, or heteroaryl or heteroaryl substituted by one to five R9; and R1, R2, R4, R5, R9 and Z are as defined in the claims. The invention also provides compositions comprising the compounds of formula (I), intermediates useful in the preparation of compounds of formula (I) and methods of using the compounds of formula (I) to control insects, acarines, nematodes or molluscs.

    摘要翻译： 本发明提供式（I）的化合物，其中P为P0，被一至五个Z式（II）取代的杂环基或杂环基; Y1，Y2，Y3和Y4彼此独立地为C-H，C-R5或氮; G1是氧或硫; X4是C1-C8卤代烷基; R4是被1至5个R9取代的芳基或芳基，或被1至5个R9取代的杂芳基或杂芳基; 并且R 1，R 2，R 4，R 5，R 9和Z如权利要求中所定义。 本发明还提供包含式（I）化合物的组合物，可用于制备式（I）化合物的中间体和使用式（I）化合物来控制昆虫，蜱，线虫或软体动物的方法。

    Isoxazoline derivatives as insecticides
    18.
    发明授权
    Isoxazoline derivatives as insecticides 有权
    异恶唑啉衍生物作为杀虫剂

    公开(公告)号：US08754053B2

    公开(公告)日：2014-06-17

    申请号：US13579637

    申请日：2011-02-17

    申请人： Thomas Pitterna ,  Myriem El Qacemi ,  Jerome Yves Cassayre ,  Peter Renold ,  Vladimir Bobosik

    发明人： Thomas Pitterna ,  Myriem El Qacemi ,  Jerome Yves Cassayre ,  Peter Renold ,  Vladimir Bobosik

    IPC分类号： A01N43/80 ,  C07D261/04 ,  C07D413/10 ,  C07D413/12 ,  C07D417/12

    CPC分类号： C07D261/04 ,  A01N43/80 ,  C07D413/10 ,  C07D413/12 ,  C07D417/12

    摘要： The present invention relates to compounds formula (I), wherein P is P1, P2, heterocyclyl or heterocyclyl substituted by one to five Z; and wherein A1, A2, A3, A4, G1, R1, R2, R3, R4, R5, R6, R17, R18, R19 and R20 are as defined in claim 1; or a salt or N-oxide thereof. Furthermore, the present invention relates to processes and intermediates for preparing compounds of formula (I), to insecticidal, acaricidal, nematicidal and molluscicidal compositions comprising the compounds of formula (I) and to methods of using the compounds of formula (I) to control insect, acarine, nematode and mollusc pests.

    摘要翻译： 本发明涉及式（I）化合物，其中P为P1，P2，被1至5个Z取代的杂环基或杂环基; 并且其中A1，A2，A3，A4，G1，R1，R2，R3，R4，R5，R6，R17，R18，R19和R20如权利要求1中所定义; 或其盐或N-氧化物。 此外，本发明涉及制备式（I）化合物的方法和中间体，其包含式（I）化合物的杀虫，杀螨，杀线虫和杀软体动物的组合物和使用式（I）化合物控制的方法 昆虫，螨虫，线虫和软体动物害虫。

    INSECTICIDAL COMPOUNDS
    20.
    发明申请
    INSECTICIDAL COMPOUNDS 有权
    杀虫剂化合物

    公开(公告)号：US20140107056A1

    公开(公告)日：2014-04-17

    申请号：US14118573

    申请日：2012-05-30

    申请人： Jerome Yves Cassayre ,  Peter Renold ,  Myriem El Qacemi ,  Thomas Pitterna ,  Julie Clementine Toueg

    发明人： Jerome Yves Cassayre ,  Peter Renold ,  Myriem El Qacemi ,  Thomas Pitterna ,  Julie Clementine Toueg

    IPC分类号： A01N43/80

    CPC分类号： A01N43/80 ,  C07D261/02 ,  C07D327/02 ,  C07D411/12 ,  C07D413/12 ,  C07D413/14

    摘要： The present invention provides compounds of formula (I): wherein A1, A2, A3 and A4 are independently of one another C—H, C—R5, or nitrogen; B1—B2—B3—B4 is —CH2—C═N—CH2—, —CH2—N—CH2—CH2—, —CH2—C═CH-0- or —CH═C—CH2-0-; G1 is oxygen or sulfur; L is a single bond or C1-C8alkylene; R1 is hydrogen, C1-C8alkyl, C1-C8alkylcarbonyl-, C1-C8alkoxy, C2-C8alkenyl, C2-C8alkynyl, C1-C8alkoxy-C1-C8alkyl, aryl or aryl substituted by one to three R6, or R1 is heterocyclyl or heterocyclyl substituted by one to three R6 or C1-C8alkoxycarbonyl-; R2 is hydrogen, C1-C8haloalkyl or C1-C8alkyl; R3 is C1-C8haloalkyl; R4 is aryl or aryl substituted by one to three R6, or R4 is heterocyclyl or heterocyclyl substituted by one to three R6; Y1 is CR7R8, C═O or C═S; Y2, Y3 and Y4 are independently CR7R8, C=0, C═S, N—R9, O, S, SO or SO2; wherein at least two adjacent ring atoms in the ring formed by Y1, Y2, Y3 and Y4 are heteroatoms; each R7 and R8 is independently hydrogen, halogen, C1-C8alkyl, or C1-C8haloalkyl; and R5, R6, R7, R8 and R9 are as defined in the claims. The invention also relates to processes and intermediates for preparing these compounds, to insecticidal, acaricidal, nematicidal and molluscicidal compositions comprising these compounds and to methods of using these compounds to control insect, acarine, nematode and mollusc pests.

    摘要翻译： 本发明提供式（I）化合物：其中A1，A2，A3和A4彼此独立地为C-H，C-R5或氮; B1-B2-B3-B4是-CH2-C≡N-CH2-，-CH2-N-CH2-CH2-，-CH2-C≡CH-O-或-CH = C-CH2-O-; G1是氧或硫; L是单键或C1-C8亚烷基; R 1是氢，C 1 -C 8烷基，C 1 -C 8烷基羰基 - ，C 1 -C 8烷氧基，C 2 -C 8烯基，C 2 -C 8炔基，C 1 -C 8烷氧基-C 1 -C 8烷基，被1至3个R 6取代的芳基或芳基，或R 1是杂环基或杂环基取代 一至三个R6或C1-C8烷氧基羰基 - ; R2是氢，C1-C8卤代烷基或C1-C8烷基; R3是C1-C8卤代烷基; R4是被一至三个R6取代的芳基或芳基，或R4是被一至三个R6取代的杂环基或杂环基; Y1是CR7R8，C = O或C = S; Y2，Y3和Y4独立地为CR7R8，C = 0，C = S，N-R9，O，S，SO或SO2; 其中由Y1，Y2，Y3和Y4形成的环中至少两个相邻的环原子是杂原子; 每个R 7和R 8独立地是氢，卤素，C 1 -C 8烷基或C 1 -C 8卤代烷基; 且R 5，R 6，R 7，R 8和R 9如权利要求中所定义。 本发明还涉及制备这些化合物的方法和中间体，包含这些化合物的杀虫，杀螨，杀线虫和杀软体动物的组合物，以及使用这些化合物来控制昆虫，螨虫，线虫和软体动物害虫的方法。