公开(公告)号：US20070112228A1

公开(公告)日：2007-05-17

申请号：US11592415

申请日：2006-11-03

Applicant: Sudip Mukhopadhyay ,  Haridasan Nair ,  Hsueh Tung ,  Michael Van Der Puy ,  Daniel Merkel ,  Rajesh Dubey ,  Jing Ji Ma ,  Barbara Light ,  Kim Fleming ,  Cheryl Bortz ,  Richard Udy

Inventor： Sudip Mukhopadhyay ,  Haridasan Nair ,  Hsueh Tung ,  Michael Van Der Puy ,  Daniel Merkel ,  Rajesh Dubey ,  Jing Ji Ma ,  Barbara Light ,  Kim Fleming ,  Cheryl Bortz ,  Richard Udy

IPC: C07C17/093

CPC classification number: C07C17/00 ,  C07C17/02 ,  C07C17/04 ,  C07C17/10 ,  C07C21/18 ,  C07C19/08 ,  C07C19/10

Abstract: A method for preparing fluorinated organic compounds comprising contacting hydrogen fluoride with at least one compound of formula I: CX3CXYCH3  Iwhere each X is independently Cl, I or Br, and each Y is independently H or F, said contacting step being carried out under conditions effective to produce a compound of formula II CF3CZCH2  IIwhere Z is Cl, I, Br, or F.

Abstract translation: 一种制备氟化有机化合物的方法，包括使氟化氢与至少一种式I化合物接触：<？in-line-formula description =“In-Line Formulas”end =“lead”→> 3 其中每个X独立地为Cl，I或Br，并且每个Y独立地为H，其中每个X独立地为H， 或F，所述接触步骤在有效产生式II化合物的条件下进行。＆lt;线内公式描述=“在线配方”末端=“铅”→CF 3 CZCH II II <？in-line-formula description =“In-line Formulas”end =“tail”？>其中Z是Cl，I，Br或F.

公开(公告)号：US09358265B2

公开(公告)日：2016-06-07

申请号：US14468276

申请日：2014-08-25

Applicant: Govind P. Dubey ,  Aruna Agarwal ,  Gurprit I. Singh ,  Gurpreet S. Gill ,  Shipra Dubey ,  Rajesh Dubey

Inventor： Govind P. Dubey ,  Aruna Agarwal ,  Gurprit I. Singh ,  Gurpreet S. Gill ,  Shipra Dubey ,  Rajesh Dubey

IPC: A01N65/00 ,  A61K36/75 ,  A61K36/48 ,  A61K36/35

CPC classification number: A61K36/75 ,  A61K36/35 ,  A61K36/48 ,  A61K2300/00

Abstract: The invention relates to a plant based formulation for the prevention and management of Irritable Bowel Syndrome (IBS) comprising of effective amount of a hydro-alcoholic extract of Acacia arabica, Aegle marmelos and Nardostachys jatamansi.

Abstract translation: 本发明涉及一种用于预防和治疗肠易激综合征（IBS）的基于植物的制剂，其包含有效量的阿拉伯胶，阿耳麦尔马斯和哈达氏菌（Nardostachys jatamansi）的含水醇提取物。

公开(公告)号：US20160051614A1

公开(公告)日：2016-02-25

申请号：US14468276

申请日：2014-08-25

Applicant: Govind P. Dubey ,  Aruna Agarwal ,  Gurprit I. Singh ,  Gurpreet S. Gill ,  Shipra Dubey ,  Rajesh Dubey

Inventor： Govind P. Dubey ,  Aruna Agarwal ,  Gurprit I. Singh ,  Gurpreet S. Gill ,  Shipra Dubey ,  Rajesh Dubey

IPC: A61K36/75 ,  A61K36/35 ,  A61K36/48

CPC classification number: A61K36/75 ,  A61K36/35 ,  A61K36/48 ,  A61K2300/00

Abstract: The invention relates to a plant based formulation for the prevention and management of Irritable Bowel Syndrome (IBS) comprising of effective amount of a hydro-alcoholic extract of Acacia arabica, Aegle marmelos and Nardostachys jatamansi.

Abstract translation: 本发明涉及一种用于预防和治疗肠易激综合征（IBS）的基于植物的制剂，其包含有效量的阿拉伯胶，阿耳麦尔马斯和哈达氏菌（Nardostachys jatamansi）的含水醇提取物。

公开(公告)号：US20070112230A1

公开(公告)日：2007-05-17

申请号：US11592761

申请日：2006-11-03

Applicant: Sudip Mukhopadhyay ,  Haridasan Nair ,  Hsueh Tung ,  Michael Van Der Puy ,  Daniel Merkel ,  Rajesh Dubey ,  Jing Ji Ma

Inventor： Sudip Mukhopadhyay ,  Haridasan Nair ,  Hsueh Tung ,  Michael Van Der Puy ,  Daniel Merkel ,  Rajesh Dubey ,  Jing Ji Ma

IPC: C07C17/093

CPC classification number: C07C17/04 ,  C07C17/00 ,  C07C17/06 ,  C07C17/206 ,  C07C17/25 ,  C07C17/26 ,  C07C17/269 ,  C07C17/272 ,  C07C17/278 ,  C07C21/18 ,  C07C19/08 ,  C07C19/10

Abstract: Disclosed are methods for producing fluorinated organic compounds, including hydrofluoropropenes, which preferably comprises converting at least one compound of formula (I): CF3CHXCH2X   (I) to at least one compound of formula (II) CF3CZCHZ   (II). where X is independently Cl, Br, I or F, and Z independently is H or F. In certain preferred embodiments, each Z is different.

Abstract translation: 公开了用于制备包括氢氟丙烯的氟化有机化合物的方法，其优选包括转化至少一种式（I）的化合物：<？in-line-formula description =“In-Line Formulas”end =“lead” 至少一种式（III）化合物（其中R 1，R 2，R 3，R 4， II）<？in-line-formula description =“In-line Formulas”end =“lead”？> CF 3 3 CZCHZ（II）。 其中X独立地为Cl，Br，I或F，Z独立地为H或F.在某些优选实施方案中，每个Z为 不同。

公开(公告)号：US20070112229A1

公开(公告)日：2007-05-17

申请号：US11592476

申请日：2006-11-03

Applicant: Sudip Mukhopadhyay ,  Haridasan Nair ,  Rajesh Dubey ,  Rajiv Singh ,  George Shia

Inventor： Sudip Mukhopadhyay ,  Haridasan Nair ,  Rajesh Dubey ,  Rajiv Singh ,  George Shia

IPC: C07C17/093

CPC classification number: C07C17/278 ,  C07C17/23 ,  C07C17/25 ,  C07C21/18 ,  C07C19/10

Abstract: Disclosed is a method for producing fluorinated organic compounds, including hydrofluoropropenes, which preferably comprises converting at least one compound of formula (I): CF3CFnCHmXa-m   (I) to at least one compound of formula (II) CF3CZCHZ   (II). where each X is independently Cl, F, I or Br; each Z is independently H or F; n is 1 or 2; m is 1, 2 or 3, provided that when n is 1, mis 1 or 2; a is 2 or 3, and a-m≧0. Certain embodiments include the step of reacting fluorinated C2 olefin, such as tetrafluoroethylene, with a Cl addition agent under conditions effective to produce a compound of formula (I).

Abstract translation: 公开了一种包括氢氟丙烯的氟化有机化合物的制备方法，其优选包括转化至少一种式（I）的化合物：<？in-line-formula description =“In-line formula”end =“lead”→> CF （I）<？in-line-formula description =“In-line-formula description =”In-line-formula description =“In- 至少一种式（II）的化合物<？in-line-formula description =“In-line Formulas”end =“lead”？> CF 3 CZCHZ（二）。 <？in-line-formula description =“在线公式”end =“tail”？>其中每个X独立为Cl，F，I或Br; 每个Z独立地为H或F; n为1或2; m为1,2或3，条件是当n为1时，为1或2; a为2或3，a-m> = 0。 某些实施方案包括在有效产生式（I）化合物的条件下，将氟化C 2烯烃如四氟乙烯与Cl加成剂反应的步骤。