Laser systems for food analysis based on reflectance ratio detection
    11.
    发明授权
    Laser systems for food analysis based on reflectance ratio detection 失效
    基于反射率检测的食品分析激光系统

    公开(公告)号:US5239180A

    公开(公告)日:1993-08-24

    申请号:US928539

    申请日:1992-08-13

    申请人: Richard H. Clarke

    发明人: Richard H. Clarke

    IPC分类号: A61B5/00 G01N21/35

    摘要: Systems and methods for material analysis are disclosed in which a material (e.g., a food of food ingredient) is illuminated at a plurality of discrete wavelengths. Measurements of the intensity of reflected light at such wavelengths are taken, and a analysis of reflection ratios for various wavelengths is performed. Changes in the reflection ratios are correlated with specific material properties such as the concentration of analytes or the condition of the material (e.g., spoilage, ripeness, degree of cooking or other processing stages).

    摘要翻译: 公开了用于材料分析的系统和方法,其中以多个离散波长照射材料(例如,食品成分的食物)。 测量这些波长的反射光的强度,并进行各种波长的反射率分析。 反射率的变化与特定材料性质(例如分析物的浓度或材料的状态(例如腐败,成熟度,烹饪程度或其他处理阶段))相关。

    RAMAN SPECTROSCOPIC MONITORING OF HEMODIALYSIS
    12.
    发明申请
    RAMAN SPECTROSCOPIC MONITORING OF HEMODIALYSIS 审中-公开
    拉曼光谱分析监测

    公开(公告)号:US20100165324A1

    公开(公告)日:2010-07-01

    申请号:US12645166

    申请日:2009-12-22

    IPC分类号: G01N33/48

    摘要: Spectroscopic systems and methods are disclosed for determining levels of at least one analyte in blood undergoing hemodialysis. In one aspect, the invention employs Raman spectroscopy to monitor and/or control hemodialysis. In one embodiment, the system uses a laser light directed to circulating blood from a patient undergoing dialysis to make Raman spectral measurements. For example, the laser light can be directed into a segment of the dialysis tubing. The system can utilize unique Raman spectroscopic signature of one or more analytes, e.g., urea, to identify and quantify such analytes against a whole blood background. Based on the spectral response, the concentration of the analytes can be monitored and/or used to control hemodialysis.

    摘要翻译: 公开了用于确定进行血液透析的血液中至少一种分析物的水平的光谱系统和方法。 在一个方面,本发明使用拉曼光谱来监测和/或控制血液透析。 在一个实施例中,系统使用指向的循环血液的激光,来自经历透析的患者进行拉曼光谱测量。 例如,激光可以被引导到透析管的一段中。 该系统可以利用一种或多种分析物(例如尿素)的独特拉曼光谱特征来鉴定和量化针对全血背景的这种分析物。 基于光谱响应,可以监测和/或使用分析物的浓度来控制血液透析。

    Catheter-delivered low resolution Raman scattering analyzing system for detecting lesions
    14.
    发明授权
    Catheter-delivered low resolution Raman scattering analyzing system for detecting lesions 失效
    导管传递的低分辨率拉曼散射分析系统,用于检测病变

    公开(公告)号:US06208887B1

    公开(公告)日:2001-03-27

    申请号:US09339524

    申请日:1999-06-24

    申请人: Richard H. Clarke

    发明人: Richard H. Clarke

    IPC分类号: A61B500

    CPC分类号: A61B5/0075 A61B5/0084

    摘要: The present invention provides low resolution Raman spectroscopic systems and methods for in-vivo detection and analysis of a lesion in a lumen of a subject. The system uses a multi-mode laser attached to a catheter in making in-vivo Raman spectroscopic measurements of the lumen. The system includes a light collector and/or a light dispersion element as well as a detector to measure spectral patterns that indicate the presence of the lesion. Based on the spectral response of the lumen, the presence (or absence) of a lesion can be determined. In addition, the components of the lesion can also be identified based on the unique Raman spectrum associated with each component.

    摘要翻译: 本发明提供了低分辨率拉曼光谱系统和用于体内检测和分析受试者的管腔中病变的方法。 该系统使用连接到导管的多模激光器进行体内拉曼光谱测量。 该系统包括光收集器和/或光分散元件以及用于测量指示病变存在的光谱图案的检测器。 基于管腔的光谱响应,可以确定病变的存在(或不存在)。 此外,还可以基于与每个组分相关联的唯一拉曼光谱来鉴定损伤的组分。

    Portable fuel analyzer for the diagnosis of fuel-related problems
on-site at the vehicle service bay
    15.
    发明授权
    Portable fuel analyzer for the diagnosis of fuel-related problems on-site at the vehicle service bay 失效
    便携式燃油分析仪,用于诊断车辆服务舱现场燃油相关问题

    公开(公告)号:US5569922A

    公开(公告)日:1996-10-29

    申请号:US507724

    申请日:1995-07-26

    申请人: Richard H. Clarke

    发明人: Richard H. Clarke

    IPC分类号: G01N21/35 G01N33/28 G01N33/22

    CPC分类号: G01N33/2829 G01N21/3577

    摘要: Method and apparatus for diagnosing fuel-related problems at the site of vehicle servicing and matching fuels to new engine designs. Fuel properties associated with a fuel sample can be measured with mid-infrared analysis. The measured fuel property values can be compared with pre-determined preferred values for the fuel properties for the particular type of vehicle. Fuel-related problems can then be identified and diagnosed based upon this comparison, and the diagnosis can be immediately displayed for the operator. In one embodiment, driveability index can be determined in situ and in real time. In other embodiments, octane number, and Reid vapor pressure can be similarly determined.

    摘要翻译: 用于在车辆维修现场诊断燃料相关问题并将燃料与新发动机设计相匹配的方法和装置。 与燃料样品相关的燃料性质可以用中红外分析来测量。 可将所测量的燃料特性值与用于特定类型车辆的燃料特性的预定优选值进行比较。 然后可以基于该比较来识别和诊断燃料相关问题,并且可以立即为操作者显示诊断。 在一个实施例中,驾驶性能指数可以在现场和实时地确定。 在其它实施方案中,可以类似地确定辛烷值和Reid蒸气压。

    Laser systems for material analysis based on reflectance ratio detection
    16.
    发明授权
    Laser systems for material analysis based on reflectance ratio detection 失效
    基于反射率检测的材料分析激光系统

    公开(公告)号:US5054487A

    公开(公告)日:1991-10-08

    申请号:US474344

    申请日:1990-02-02

    申请人: Richard H. Clarke

    发明人: Richard H. Clarke

    IPC分类号: A61B5/00

    摘要: Systems and methods for non-invasive material analysis are disclosed in which a material (e.g., a liquid such as blood) is illuminated at a plurality of discrete wavelengths. Measurements of the intensity of reflected light at such wavelengths are taken, and an analysis of reflection ratios for various wavelengths is performed. Changes in the reflection ratios can be correlated with specific material properties such as the concentration of analytes (e.g., oxygen content, glucose levels, cholesterol or drugs in a subject's circulatory system).

    摘要翻译: 公开了用于非侵入性材料分析的系统和方法,其中以多个离散波长照射材料(例如,诸如血液的液体)。 对这些波长的反射光的强度进行测量,并进行各种波长的反射率分析。 反射率的变化可以与具体的材料性质相关,例如分析物的浓度(例如,受试者的循环系统中的氧含量,葡萄糖水平,胆固醇或药物)。

    Raman spectroscopic monitoring of hemodialysis
    17.
    发明授权
    Raman spectroscopic monitoring of hemodialysis 失效
    拉曼光谱监测血液透析

    公开(公告)号:US07326576B2

    公开(公告)日:2008-02-05

    申请号:US10410051

    申请日:2003-04-09

    摘要: Spectroscopic systems and methods are disclosed for determining levels of at least one analyte in blood undergoing hemodialysis. In one aspect, the invention employs Raman spectroscopy to monitor and/or control hemodialysis. In one embodiment, the system uses a laser light directed to circulating blood from a patient undergoing dialysis to make Raman spectral measurements. For example, the laser light can be directed into a segment of the dialysis tubing. The system can utilize unique Raman spectroscopic signature of one or more analytes, e.g., urea, to identify and quantify such analytes against a whole blood background. Based on the spectral response, the concentration of the analytes can be monitored and/or used to control hemodialysis.

    摘要翻译: 公开了用于确定进行血液透析的血液中至少一种分析物的水平的光谱系统和方法。 在一个方面,本发明使用拉曼光谱来监测和/或控制血液透析。 在一个实施例中,系统使用指向的循环血液的激光,来自经历透析的患者进行拉曼光谱测量。 例如,激光可以被引导到透析管的一段中。 该系统可以利用一种或多种分析物(例如尿素)的独特拉曼光谱特征来鉴定和量化针对全血背景的这种分析物。 基于光谱响应,可以监测和/或使用分析物的浓度来控制血液透析。

    Probe assemblies for Raman spectroscopy
    18.
    发明授权
    Probe assemblies for Raman spectroscopy 失效
    用于拉曼光谱的探针组件

    公开(公告)号:US06897951B2

    公开(公告)日:2005-05-24

    申请号:US10367238

    申请日:2003-02-14

    IPC分类号: G01J3/44 G01N21/27 G01N21/65

    摘要: Raman spectroscopy probe assemblies are disclosed for use with portable and/or handheld analyzers. The probes are also adaptable to sample liquids, and/or powders, tablets and/or other solids and are capable of withstanding harsh environmental conditions. The probes include an optical head assembly, associated optical fibers and replaceable sampling tubes. In one aspect of the invention, a simple orthogonal optical head assembly is disclosed that does not require collinear optical paths. The orthogonal arrangement of input and captured light paths also reduces the need for precise alignment of the optical components. The orthogonal optical head assemblies of the present invention are well suited to accommodate the shutoff mechanisms of the present invention. In another aspect of the invention, sampling tubes, and replaceable end caps for such tubes, are disclosed that facilitate hand measurements of substances.

    摘要翻译: 公开了用于便携式和/或手持式分析仪的拉曼光谱探测器组件。 探针还适用于液体和/或粉末,片剂和/或其他固体的样品,并能够承受恶劣的环境条件。 探头包括光头组件,相关联的光纤和可更换的采样管。 在本发明的一个方面,公开了一种不需要共线光路的简单正交光学头组件。 输入和捕获的光路的正交布置也减少了对光学部件的精确对准的需要。 本发明的正交光学头组件非常适合于适应本发明的切断机构。 在本发明的另一方面,公开了用于这种管的取样管和可替换的端盖,其便于手测量物质。

    Apparatus for marking and identifying liquids
    19.
    发明授权
    Apparatus for marking and identifying liquids 有权
    用于标记和识别液体的设备

    公开(公告)号:US06881381B1

    公开(公告)日:2005-04-19

    申请号:US09219288

    申请日:1998-12-22

    摘要: A liquid can be marked for identification purposes with at least first and second miscible markers. The markers are mixed in the liquid so that the ratio of the concentration of the first marker to the concentration of the second marker is substantially equal to a predetermined value. Thus, by comparing the ratio of the measured concentration of the first marker to the measured concentration of the second marker with predetermined values the liquid can be uniquely identified. The detectors can be connected to a processor and control unit (22) for initiation of testing, for processing of detection signal from the detectors, and for display of readout information. Processor and control unit (22) can include a look up table (23) for storing information about marking patterns, a comparison element (35) for comparing measured values with values supplied by look up table (23), and a display (30).

    摘要翻译: 液体可以用至少第一和第二混溶标记物进行标识。 标记物在液体中混合,使得第一标记物的浓度与第二标记物的浓度之比基本上等于预定值。 因此,通过将第一标记物的测量浓度与第二标记物的测量浓度的比率与预定值进行比较,可以唯一地识别液体。 检测器可以连接到处理器和控制单元(22),用于启动测试,用于处理来自检测器的检测信号,以及显示读出信息。 处理器和控制单元(22)可以包括用于存储关于标记图案的信息的查询表(23),用于将测量值与由查找表(23)提供的值进行比较的比较元件(35) 。

    High accuracy mass sensor for monitoring fluid quantity in storage tanks
    20.
    发明授权
    High accuracy mass sensor for monitoring fluid quantity in storage tanks 失效
    用于监测储罐液量的高精度质量传感器

    公开(公告)号:US5245869A

    公开(公告)日:1993-09-21

    申请号:US769865

    申请日:1991-10-01

    IPC分类号: G01F23/16 G01F23/18 G01M3/32

    摘要: A mass sensoring system for monitoring the amount of fluid in a storage tank with an accuracy high enough to determine both the quantity present and the potential loss of fluid at a loss rate of 0.05 gal/hr or at least 0.1 gal/hr. The system utilizes a pressure sensor positioned at the bottom of the tank and in contact with the fluid. This device includes a bellows unit whose displacement is correlated to changes in the mass of fluid in which it is immersed, and a transducer for monitoring the position of the bellows, wherein the interior of the bellows unit is in the same atmosphere as the sensor, and the sensor is in communication with the vapor pressure immediately above the fluid in the tank. The outside of the bellows is subjected to the stored fluid. A multiple-capsule bellows assembly is coupled to an LDVT transducer in a thermal-expansion-cancelling configuration of the invention.

    摘要翻译: 一种质量传感系统,用于以0.05加仑/小时或至少0.1加仑/小时的损失速率监测存储罐中的流体的量,其精度足够高以确定流体的存在量和潜在损失。 该系统利用位于罐底部并与流体接触的压力传感器。 该装置包括波纹管单元,其位移与其浸入的流体的质量变化相关,以及用于监测波纹管的位置的换能器,其中波纹管单元的内部处于与传感器相同的气氛中, 并且传感器与罐中流体正上方的蒸汽压力相通。 波纹管的外部经受存储的流体。 在本发明的热膨胀消除结构中,多个胶囊波纹管组件联接到LDVT换能器。