Methods for fine powder formation
    12.
    发明授权
    Methods for fine powder formation 有权
    精细粉末形成方法

    公开(公告)号:US07794754B2

    公开(公告)日:2010-09-14

    申请号:US11385513

    申请日:2006-03-21

    IPC分类号: A61K38/00 C07K14/00

    摘要: Improved methods for forming fine particles of a material have been developed, wherein the method steps include dissolving the material in a solvent to form a dilute solution, immobilizing the dilution solution, and then removing the solvent to yield particles of the material. Methods of immobilizing the dilute solution include freezing, gelation, and chelation. In a preferred embodiment, the immobilized solvent is removed by lyophilization, i.e. reducing the ambient pressure while avoiding application of sufficient heat to power a phase transition. Essentially any material and solvent for the material can be used in the methods described herein. Proteins and peptides in an aqueous solvent are the preferred systems.

    摘要翻译: 已经开发了用于形成材料细颗粒的改进方法,其中所述方法步骤包括将所述材料溶解在溶剂中以形成稀溶液,固定所述稀释溶液,然后除去所述溶剂以产生所述材料的颗粒。 固定稀释溶液的方法包括冷冻,凝胶化和螯合。 在一个优选的实施方案中,通过冻干除去固定的溶剂,即降低环境压力,同时避免施加足够的热量以对相变作用。 基本上可以在本文所述的方法中使用材料的任何材料和溶剂。 水性溶剂中的蛋白质和肽是优选的体系。

    Methods for fine powder formation
    13.
    发明授权
    Methods for fine powder formation 失效
    精细粉末形成方法

    公开(公告)号:US07278843B2

    公开(公告)日:2007-10-09

    申请号:US10224676

    申请日:2002-08-20

    IPC分类号: B29B9/00

    摘要: Improved methods for forming fine particles of a material have been developed, wherein the method steps include dissolving the material in a solvent to form a dilute solution, immobilizing the dilution solution, and then removing the solvent to yield particles of the material. Methods of immobilizing the dilute solution include freezing, gelation, and chelation. In a preferred embodiment, the immobilized solvent is removed by lyophilization, i.e. reducing the ambient pressure while avoiding application of sufficient heat to power a phase transition. Essentially any material and solvent for the material can be used in the methods described herein. Proteins and peptides in an aqueous solvent are the preferred systems.

    摘要翻译: 已经开发了用于形成材料细颗粒的改进方法,其中所述方法步骤包括将所述材料溶解在溶剂中以形成稀溶液,固定所述稀释溶液,然后除去所述溶剂以产生所述材料的颗粒。 固定稀释溶液的方法包括冷冻,凝胶化和螯合。 在一个优选的实施方案中,通过冻干除去固定的溶剂,即降低环境压力,同时避免施加足够的热量以对相变作用。 基本上可以在本文所述的方法中使用材料的任何材料和溶剂。 水性溶剂中的蛋白质和肽是优选的体系。

    Level detector for storage tanks for fluids
    14.
    发明授权
    Level detector for storage tanks for fluids 失效
    用于液体储罐的液位探测器

    公开(公告)号:US06959599B2

    公开(公告)日:2005-11-01

    申请号:US10411343

    申请日:2003-04-10

    IPC分类号: G01F23/24 G01F23/00

    CPC分类号: G01F23/246

    摘要: A level detector for storage tanks for fluids comprises a microprocessor, a network of resistive elements connected in series or parallel, and a plurality of conductive elements between them, connected across a power source. The resistive elements have a high temperature coefficient, and are heated by passing a high electric current through them, after which a low electric current is passed through them and the voltage between them is sampled by the microprocessor. The resistive elements lose heat through conduction, so that a pair of resistive elements can be detected having differential cooling between them as a consequence of being adjacent to the void within the tank or the fluid within the tank. Thus, an approximation of the fluid level within the storage tank can be determined and signalled remotely.

    摘要翻译: 用于流体存储罐的液位检测器包括微处理器,串联或并联连接的电阻元件的网络,以及跨过电源连接的多个在它们之间的导电元件。 电阻元件具有高温度系数,并通过使高电流通过它们而被加热,之后低电流通过它们,并且它们之间的电压被微处理器采样。 电阻元件通过导电而失去热量,从而可以检测出一对电阻元件,它们之间具有差别的冷却作用,因为它们与罐内的空隙或槽内的流体相邻。 因此,可以确定储存罐内的液位的近似值并远程发出信号。

    Methods for fine powder formation
    15.
    发明授权
    Methods for fine powder formation 有权
    精细粉末形成方法

    公开(公告)号:US06440463B1

    公开(公告)日:2002-08-27

    申请号:US09543309

    申请日:2000-04-05

    IPC分类号: A61K914

    摘要: Improved methods for forming fine particles of a material have been developed, wherein the method steps include dissolving the material in a solvent to form a dilute solution, immobilizing the dilution solution, and then removing the solvent to yield particles of the material. Methods of immobilizing the dilute solution include freezing, gelation, and chelation. In a preferred embodiment, the immobilized solvent is removed by lyophilization, i.e. reducing the ambient pressure while avoiding application of sufficient heat to power a phase transition. Essentially any material and solvent for the material can be used in the methods described herein. Proteins and peptides in an aqueous solvent are the preferred systems.

    摘要翻译: 已经开发了用于形成材料细颗粒的改进方法,其中所述方法步骤包括将所述材料溶解在溶剂中以形成稀溶液,固定所述稀释溶液,然后除去所述溶剂以产生所述材料的颗粒。 固定稀释溶液的方法包括冷冻,凝胶化和螯合。 在一个优选的实施方案中,通过冻干除去固定的溶剂,即降低环境压力,同时避免施加足够的热量以对相变作用。 基本上可以在本文所述的方法中使用材料的任何材料和溶剂。 水性溶剂中的蛋白质和肽是优选的体系。

    Electronic ballast with closed loop control using composite current and voltage feedback and method thereof
    19.
    发明申请
    Electronic ballast with closed loop control using composite current and voltage feedback and method thereof 失效
    电子镇流器采用复合电流和电压反馈闭环控制及其方法

    公开(公告)号:US20050212458A1

    公开(公告)日:2005-09-29

    申请号:US10809948

    申请日:2004-03-26

    IPC分类号: H05B37/00 H05B41/288

    CPC分类号: H05B41/2886 Y02B20/202

    摘要: An electronic control system especially for non-linear loads, such as high pressure sodium (HPS) lamps, includes an active power factor correction circuit (APFC). The system provides a power factor correction of above 0.95; total harmonic distortion (THD) below 5%; lamp crest factor (LCF) close to unity; efficient power consumption and reliable open circuit voltage (OCV) under all power line conditions. A ballast would include integrated circuits (ICs) and a four-arm transistor bridge which is directly driven by integrated circuits. The bridge generates reversal of polarity to the load. An approximate average current feedback is derived from a load current. A resistor divider in parallel with the load provides voltage feedback. The average current feedback and voltage feedback are added together to provide an approximation of power consumed by the load, without the complex circuitry required for a true power feedback of current multiplied by voltage. That composite feedback signal is transmitted to the integrated circuit (IC) which compares it with an internal reference voltage and which adjusts the IC output to minimize the error.

    摘要翻译: 特别是用于非线性负载的电子控制系统,例如高压钠(HPS)灯,包括有源功率因数校正电路(APFC)。 该系统提供了0.95以上的功率因数校正; 总谐波失真(THD)低于5%; 灯头因数(LCF)接近统一; 在所有电力线条件下,高效的功耗和可靠的开路电压(OCV)。 镇流器将包括集成电路(IC)和由集成电路直接驱动的四臂晶体管桥。 桥对负载产生极性反转。 从负载电流得到近似的平均电流反馈。 与负载并联的电阻分压器提供电压反馈。 将平均电流反馈和电压反馈相加在一起,以提供负载消耗的功率的近似值,而不需要电流乘以电压的真实功率反馈所需的复杂电路。 该复合反馈信号被传输到集成电路(IC),该集成电路将其与内部参考电压进行比较,并调整IC输出以最小化误差。

    Information processing system for counting coughs or evaluating other
activities of a patient
    20.
    发明授权
    Information processing system for counting coughs or evaluating other activities of a patient 失效
    信息处理系统用于计数或评估患者的其他活动

    公开(公告)号:US5197490A

    公开(公告)日:1993-03-30

    申请号:US510936

    申请日:1990-04-19

    IPC分类号: A61B5/00 A61B5/11

    摘要: A system using audio and visual information to count coughs or evaluate other discrete information, including respiration and heart rate, relating to a patient in a fixed location such as a bed is disclosed. The system provides movement- and sound-based information derived from the patient's activities to a storage device and subsequently to a signal processing apparatus. One embodiment of the invention includes a pressure transducer, a video camera, a directional microphone, and a videocassette recorder (VCR) having two audio channels. Signals obtained from the transducer and microphone are transmitted to the two audio channel inputs of the VCR, while movement of the patient is recorded using the video camera connected to the video channel input of the VCR. Part or all of the information stored using the VCR may be transmitted to signal processing equipment and frequency filtered to determine the presence and number of coughs, and any remaining information (e.g. the video data) may be used to confirm the count. Because various conditions manifest themselves in movements having different frequency characteristics, the present system, as appropriately modified, also can be used to determine the presence of symptoms such as restlessness and thereby evaluate the effectiveness of medicines such as sedatives and hypnotics.

    摘要翻译: 公开了一种使用音频和视觉信息计算咳嗽或评估与固定位置(例如床)中的患者有关的其它离散信息(包括呼吸和心率)的系统。 该系统将从患者活动得到的基于运动和声音的信息提供给存储装置,随后提供给信号处理装置。 本发明的一个实施例包括压力换能器,摄像机,定向麦克风和具有两个音频通道的录像机(VCR)。 从传感器和麦克风获得的信号被传送到VCR的两个音频通道输入端,同时使用连接到VCR的视频通道输入的摄像机记录病人的移动。 使用VCR存储的信息的部分或全部可以被发送到信号处理设备并经频率滤波以确定咳嗽的存在和数量,并且可以使用任何剩余信息(例如,视频数据)来确认计数。 由于各种条件表现为具有不同频率特征的运动,所以适当修改的本系统也可用于确定诸如不安的症状的存在,从而评估诸如镇静剂和催眠药之类的药物的有效性。