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16 条记录 (耗时 0.028 秒)

    AMINE COMPOUND AND USE FOR SAME
    13.
    发明申请
    AMINE COMPOUND AND USE FOR SAME 失效
    胺化合物和用途

    公开(公告)号：US20130245280A1

    公开(公告)日：2013-09-19

    申请号：US13878131

    申请日：2011-09-30

    申请人： Ryo Matsui ,  Toru Yamazaki ,  Shigeyuki Kikumoto

    发明人： Ryo Matsui ,  Toru Yamazaki ,  Shigeyuki Kikumoto

    IPC分类号： C07D233/64

    CPC分类号： C07D233/64

    摘要： Provided is an ester of 3-[(4-dipropylamino-butyl)(4-{[(1H-imidazole-2-ylmethyl)(1-methyl-1H-imidazole-2-ylmethyl)amino]methyl}benzyl)amino]propionic acid which is easily hydrolyzed in serum. The amine compound of the present invention is an ester compound represented by general formula (1). (In general formula (1), n is 1-4, and R1 and R2 represent an alkyl group having 1-3 carbon atoms.)

    摘要翻译： 提供了3 - [（4-二丙基氨基 - 丁基）（4 - {[（1H-咪唑-2-基甲基）（1-甲基-1H-咪唑-2-基甲基）氨基]甲基}苄基）氨基] 在血清中容易水解的丙酸。 本发明的胺化合物是通式（1）表示的酯化合物。 （通式（1）中，n为1-4，R 1和R 2表示碳原子数1〜3的烷基。）

    Transmission and method of up-shifting for transmission
    15.
    发明授权
    Transmission and method of up-shifting for transmission 失效
    传输和传输方式

    公开(公告)号：US07882758B2

    公开(公告)日：2011-02-08

    申请号：US12233226

    申请日：2008-09-18

    申请人： Katsumi Kubo ,  Ryo Matsui ,  Kouhei Ohsono ,  Toshio Hiyoshi

    发明人： Katsumi Kubo ,  Ryo Matsui ,  Kouhei Ohsono ,  Toshio Hiyoshi

    IPC分类号： F16H3/08 ,  F16H59/00

    CPC分类号： F16H63/30 ,  F16D21/04 ,  F16D41/12 ,  F16H3/083 ,  F16H3/10 ,  F16H2063/3096 ,  Y10T74/19251 ,  Y10T74/19279 ,  Y10T74/19465

    摘要： The driving force can be transmitted at the time of both acceleration and deceleration in an engaged state where a first engagement face of a strut is forced to protrude inside a cutaway of a gear. The driving force is transmitted at the time of acceleration and the transmission of the driving force can be cut off at the time of deceleration in a one-way state where the first engagement face of the strut and the cutaway of the gear are made either to engage with or to disengage from each other in accordance with the rotational direction of the gear relative to the rotational shaft. The transmission of the driving force can be cut off at the time of both acceleration and deceleration in a disengaged state where the first engagement face of the strut is forced to withdraw from the cutaway of the gear. In addition, the decreasing of the transmission efficiency caused by friction between the strut and the gear can be prevented.

    摘要翻译： 驱动力可以在加速和减速两者处于啮合状态下传递，其中支柱的第一接合面被迫在齿轮的切口内突出。 驱动力在加速时传递，并且在将支柱的第一接合面和齿轮的切口形成为单向状态的减速时可以切断驱动力的传递， 根据齿轮相对于旋转轴的旋转方向与第二齿轮啮合或脱离啮合。 驱动力的传递在加强和减速两者都可以在支柱的第一啮合面被迫从齿轮的切口中退出的脱离状态下被切断。 此外，可以防止由支柱和齿轮之间的摩擦引起的传动效率的降低。

    Amine compound and use thereof
    16.
    发明授权
    Amine compound and use thereof 有权
    胺化合物及其用途

    公开(公告)号：US07833991B2

    公开(公告)日：2010-11-16

    申请号：US11704860

    申请日：2007-02-09

    申请人： Toru Yamazaki ,  Shigeyuki Kikumoto ,  Masahiro Ono ,  Atsushi Saitou ,  Haruka Takahashi ,  Sei Kumakura ,  Kunitaka Hirose ,  Mikiro Yanaka ,  Yoshiyuki Takemura ,  Shigeru Suzuki ,  Ryo Matsui

    发明人： Toru Yamazaki ,  Shigeyuki Kikumoto ,  Masahiro Ono ,  Atsushi Saitou ,  Haruka Takahashi ,  Sei Kumakura ,  Kunitaka Hirose ,  Mikiro Yanaka ,  Yoshiyuki Takemura ,  Shigeru Suzuki ,  Ryo Matsui

    IPC分类号： C07D403/02 ,  A01N43/50

    CPC分类号： C07D233/64 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D403/14 ,  C07D405/14 ,  C07D417/12 ,  C07D417/14

    摘要： It is intended to provide novel amine compounds which are efficacious against diseases such as infection with HIV virus, rheumatism and cancer metastasis. Namely, amine compounds represented by the following general formula (1): In a typical case, A1 and A2 represent each an optionally substituted monocyclic or polycyclic aromatic heterocycle; W represents cyclic C3-10 alkylene, an optionally substituted monocyclic or polycyclic aromatic heterocycle, a monocyclic or polycyclic aromatic ring or a partly saturated polycyclic aromatic ring; X represents O, CH2, C(═O) or NR11; and D is a group represented by the following general formula (4) or (6). In the formula (6), Q represents a single bond, S, O or NR12; and Y is a group represented by the following general formula (7). z represents an optionally substituted monocyclic or polycyclic aromatic ring. In the formula (6), B represents NR25R26. In the above formulae, R1 to R26 each represents hydrogen, alkyl, alkenyl or alkynyl.

    摘要翻译： 旨在提供对HIV病毒感染，风湿病和癌症转移等疾病有效的新型胺化合物。 即，由以下通式（1）表示的胺化合物：在典型情况下，A1和A2各自表示任选取代的单环或多环芳族杂环; W表示环状C 3-10亚烷基，任选取代的单环或多环芳族杂环，单环或多环芳环或部分饱和多环芳环; X表示O，CH 2，C（= O）或NR 11; D为由以下通式（4）或（6）表示的基团。 在式（6）中，Q表示单键，S，O或NR 12; Y为由以下通式（7）表示的基团。 z表示任选取代的单环或多环芳环。 式（6）中，B表示NR25R26。 在上式中，R 1至R 26各自表示氢，烷基，烯基或炔基。