公开(公告)号：US20220118032A1

公开(公告)日：2022-04-21

申请号：US17521383

申请日：2021-11-08

Applicant: Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Kirankumar Beede ,  Sivakumar Arumugam

Inventor： Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Kirankumar Beede ,  Sivakumar Arumugam

IPC: A61K35/741 ,  C12N1/20 ,  C12Q1/689 ,  C12P7/56 ,  A61K9/20

Abstract: The present invention discloses a novel fructophilic lactic acid producing bacteria Bacillus coagulans strain FF-7 (MTCC 25235) and the process of isolation and characterization of the bacteria.

公开(公告)号：US11213553B2

公开(公告)日：2022-01-04

申请号：US15901962

申请日：2018-02-22

Applicant: Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Sivakumar Arumugam ,  Furqan Ali ,  Shaheen Majeed

Inventor： Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Sivakumar Arumugam ,  Furqan Ali ,  Shaheen Majeed

IPC: A61K39/00 ,  A61K39/38 ,  A61K39/07 ,  A01N63/00 ,  A61K35/742 ,  A61P1/14 ,  A61K9/00 ,  A61K9/48 ,  A61K9/20 ,  A23L33/135 ,  A61K35/00

Abstract: Disclosed is the hypolipidemic potential of Bacillus coagulans. More specifically the invention discloses the cholesterol lowering potential of Bacillus coagulans MTCC 5856 and therapeutic/biological indications thereof.

公开(公告)号：US11197898B2

公开(公告)日：2021-12-14

申请号：US16410054

申请日：2019-05-13

Applicant: Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Furqan Ali ,  Sivakumar Arumugam ,  Shaheen Majeed ,  Kirankumar Beede

Inventor： Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Furqan Ali ,  Sivakumar Arumugam ,  Shaheen Majeed ,  Kirankumar Beede

IPC: A01N63/00 ,  A61K35/742 ,  C12N5/00 ,  A61P3/10 ,  A61P29/00 ,  A61K9/20 ,  C12N1/20 ,  A61K9/19 ,  A61K9/48 ,  A61P1/16

Abstract: The present invention discloses a novel fructophilic lactic acid producing bacteria Bacillus coagulans strain FF-7 (MTCC 25235) and the process of isolation and characterization of the bacteria. The invention also discloses the biological applications/therapeutic use of fructophilic lactic acid producing bacteria in increased utilization of fructose from food stuff and in the managing disorders related to high fructose intake.

公开(公告)号：US11123382B2

公开(公告)日：2021-09-21

申请号：US15995454

申请日：2018-06-01

Applicant: Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Sivakumar Arumugam ,  Furqan Ali ,  Shaheen Majeed ,  Lakshmi Mundkur

Inventor： Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Sivakumar Arumugam ,  Furqan Ali ,  Shaheen Majeed ,  Lakshmi Mundkur

IPC: A61K35/742 ,  A61K9/00 ,  A61P17/08 ,  A61P17/14 ,  A61Q7/00 ,  A61K8/99 ,  A61K47/32 ,  A61K47/18 ,  A61K47/44

Abstract: Disclosed are hair care compositions containing partially purified extracellular metabolite preparation from strains of Bacillus coagulans. Specifically, the uses of compositions containing extracellular metabolite preparation from a strain of Bacillus coagulans for increasing hair growth, inhibition of 5α-reductase and proliferation of follicle dermal papilla cells and in the management of androgenic alopecia, are disclosed.

公开(公告)号：US10260112B2

公开(公告)日：2019-04-16

申请号：US15276912

申请日：2016-09-27

Applicant: Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Sivakumar Arumugam ,  Furqan Ali

Inventor： Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Sivakumar Arumugam ,  Furqan Ali

IPC: C12P19/34 ,  C12Q1/689

Abstract: The present invention discloses novel oligonucleotide primer sequences BC1, BC2 and BC3 for the identification of Bacillus coagulans. The invention also discloses a PCR based method for the identification of Bacillus coagulants using the aforesaid primers, wherein positive amplification with primer sets BC1, BC2 and negative amplification with primer set BC3 confirms the presence of Bacillus coagulans.

公开(公告)号：US09596861B2

公开(公告)日：2017-03-21

申请号：US14576411

申请日：2014-12-19

Applicant: Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Sivakumar Arumugam ,  Furqan Ali

Inventor： Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Sivakumar Arumugam ,  Furqan Ali

IPC: A61K35/00 ,  A01N63/02 ,  C12N1/20 ,  C12R1/07 ,  A01N31/08 ,  A01N37/12 ,  C12R1/085 ,  C12R1/19 ,  C12R1/385 ,  C12R1/42 ,  C12R1/445 ,  C12R1/45 ,  C12R1/46

CPC classification number: A01N63/02 ,  A01N31/08 ,  A01N37/12 ,  C12N1/20 ,  C12R1/07 ,  C12R1/085 ,  C12R1/19 ,  C12R1/385 ,  C12R1/42 ,  C12R1/445 ,  C12R1/45 ,  C12R1/46 ,  A01N65/08

Abstract: Method of extracting a partially purified extracellular metabolite composition from Bacillus coagulans MTCC 5856 and its antimicrobial effects thereof are described.

公开(公告)号：US20160324163A1

公开(公告)日：2016-11-10

申请号：US15214699

申请日：2016-07-20

Applicant: Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Sivakumar Arumugam ,  Furqan Ali

Inventor： Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Sivakumar Arumugam ,  Furqan Ali

IPC: A01N63/02 ,  A01N31/08 ,  C12N1/20 ,  C12R1/46 ,  C12R1/085 ,  C12R1/45 ,  C12R1/19 ,  C12R1/385 ,  C12R1/42 ,  A01N37/12 ,  C12R1/445

CPC classification number: A01N63/02 ,  A01N31/08 ,  A01N37/12 ,  C12N1/20 ,  C12R1/07 ,  C12R1/085 ,  C12R1/19 ,  C12R1/385 ,  C12R1/42 ,  C12R1/445 ,  C12R1/45 ,  C12R1/46 ,  A01N65/08

Abstract: Disclosed is a method for producing partially purified extracellular metabolite preparation from the probiotic bacterial strain Bacillus coagulans SBC-37 (Deposited in the Microbial Type Culture Collection and Gene Bank as strain number MTCC 5856) exhibiting 99% genetic homology with the known bacterial strains Bacillus coagulans ATCC 31284, Bacillus coagulans NBRC 3887 and Bacillus coagulans ATCC 7050. Also disclosed is the anti-microbial profile of said extracellular metabolite preparation against a panel of microbial pathogens, including synergistic anti-microbial effects of preparation when combined with a synergistic preservative blend comprising from about 61% w/w of thymol, about 38% of monolaurin and about 1% w/w of magnolol obtained from supercritical fluid extracts of Magnolia officinalis. The extracellular metabolite preparation alone or the combination of said extracellular metabolite preparation and preservative blend also inhibits microbial biofilm formation in a synergistic manner.

公开(公告)号：US12257274B2

公开(公告)日：2025-03-25

申请号：US17521383

申请日：2021-11-08

Applicant: Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Kirankumar Beede ,  Sivakumar Arumugam

Inventor： Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Kirankumar Beede ,  Sivakumar Arumugam

IPC: A61K35/741 ,  A61K9/20 ,  C12N1/20 ,  C12P7/56 ,  C12Q1/689 ,  C12R1/07

Abstract: The present invention discloses a novel fructophilic lactic acid producing bacteria Bacillus coagulans strain FF-7 (MTCC 25235) and the process of isolation and characterization of the bacteria.

公开(公告)号：US11299706B2

公开(公告)日：2022-04-12

申请号：US16281120

申请日：2019-02-21

Applicant: Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Anju Majeed ,  Nooruddin Thajuddin ,  Sivakumar Arumugam ,  Krishnamurthy Kulithalai Viswanathan ,  Samuel Thomas Manoharan ,  Furqan Ali ,  John Adams Sebastian ,  Jamsheeda Moothedath ,  Muthuraman Gnanamani ,  Kirankumar Beede

Inventor： Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Anju Majeed ,  Nooruddin Thajuddin ,  Sivakumar Arumugam ,  Krishnamurthy Kulithalai Viswanathan ,  Samuel Thomas Manoharan ,  Furqan Ali ,  John Adams Sebastian ,  Jamsheeda Moothedath ,  Muthuraman Gnanamani ,  Kirankumar Beede

IPC: C12N1/14 ,  C12N1/20 ,  A61K36/9066 ,  A61K31/216 ,  C12R1/645 ,  C12R1/38

Abstract: The present invention discloses a novel endophytic fungi, Ovatospora brasiliensis MTCC 25236 for the bioconversion of curcuminoids to Calebin-A and a method for its isolation from the rhizomes of Curcuma sp. The invention also discloses a method for the bioconversion of curcuminoids to Calebin-A using an endophytic fungi Ovatospora brasiliensis MTCC 25236 and bacterial species, Acinetobacter johnsonii and Pseudomonas putida.

公开(公告)号：US11298381B2

公开(公告)日：2022-04-12

申请号：US16396876

申请日：2019-04-29

Applicant: Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Furqan Ali ,  Sivakumar Arumugam ,  Shaheen Majeed ,  Lakshmi Mundkur ,  Anurag Pande

Inventor： Muhammed Majeed ,  Kalyanam Nagabhushanam ,  Furqan Ali ,  Sivakumar Arumugam ,  Shaheen Majeed ,  Lakshmi Mundkur ,  Anurag Pande

IPC: A01N63/00 ,  A61K35/742 ,  C12N1/20

Abstract: The present invention discloses a composition comprising heat inactivated spores and/or comprising heat inactivated vegetative cells of probiotic bacteria Bacillus coagulans, and a process for preparing the same. The invention also discloses a method of modulating immune function in mammals by activating macrophages, using a composition comprising Bacillus coagulans in the form of live or heat inactivated spore and/or vegetative cells.