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公开(公告)号：US20090247666A1
公开(公告)日：2009-10-01
申请号：US12395495
申请日：2009-02-27
Applicant: Ya-Jen Yu , Chin Fu Chen , Tsai-Yu Lin , Shao-Jen Yeh , Shian-Yih Wang , Po-Liang Lai
Inventor： Ya-Jen Yu , Chin Fu Chen , Tsai-Yu Lin , Shao-Jen Yeh , Shian-Yih Wang , Po-Liang Lai
CPC classification number: A61L24/0042 , A61L24/046 , C08G63/664 , C08G69/14 , C08G69/42 , C08L67/04 , C08L71/02
Abstract: The disclosed is a biodegradable copolymer, an amphiphilic diblock copolymer, composed of a hydrophilic segment and a hydrophobic segment. The hydrophilic segment is an endcapped PEG or derivatives thereof. The hydrophilic segment is a random polymer polymerized of lactone or cyclic C3-C6 molecule and lactic acid/glycolic acid. There is no coupling agent between the hydrophilic and hydrophobic segments, and the biodegradable copolymer is formed by one-pot ring-opening polymerization. The biodegradable copolymer can be dissolved in water to form a thermosensitive material having a phase transfer temperature of 25 to 50° C., thereby being applied to biological activity factor delivery, tissue engineering, cell culture and biological glue.
Abstract translation: 所公开的是由亲水链段和疏水链段组成的可生物降解的共聚物，两亲二嵌段共聚物。 亲水片段是封端的PEG或其衍生物。 亲水段是内酯或环状C 3 -C 6分子和乳酸/乙醇酸聚合的无规聚合物。 亲水和疏水链段之间没有偶联剂，生物降解共聚物是通过一锅开环聚合形成的。 可生物降解的共聚物可以溶解在水中以形成相转移温度为25-50℃的热敏材料，从而适用于生物活性因子递送，组织工程，细胞培养和生物胶。
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公开(公告)号：US20090004731A1
公开(公告)日：2009-01-01
申请号：US12155785
申请日：2008-06-10
Applicant: Ming-Cheng Shih , Chin-Fu Chen , Rung-Jiun Gau , Yu-Shih Weng , Ya-Jen Yu , Shao-Jen Yeh
Inventor： Ming-Cheng Shih , Chin-Fu Chen , Rung-Jiun Gau , Yu-Shih Weng , Ya-Jen Yu , Shao-Jen Yeh
CPC classification number: C12M25/14
Abstract: A cell culture apparatus and a method for fabricating the cell culture apparatus are disclosed, the method comprises forming at least one fillister on a biomaterial composite layer by photolithography, wherein the biomaterial composite layer contains two gel materials. One is a bio-compatible hydrogel composition having various weight ratio of: 2-hydroxyethylmathacrylate (HEMA), bisphenol A and glycidyl methacrylate (bis-GMA), triethylene glycol dimethacrylate (TEGDMA), r-methacryloxypropyl trimethoxysilane (MAPTMS), α,α-diethoxyacetophenone (DEAP), and the other one is a photo-sensitive silica gel composition.
Abstract translation: 公开了一种细胞培养装置和细胞培养装置的制造方法，该方法包括通过光刻法在生物材料复合层上形成至少一个填充物，其中生物材料复合层含有两种凝胶材料。 一种是具有各种重量比的生物相容性水凝胶组合物：2-羟乙基甲基丙烯酸酯（HEMA），双酚A和甲基丙烯酸缩水甘油酯（双-GMA），三乙二醇二甲基丙烯酸酯（TEGDMA），γ-甲基丙烯酰氧基丙基三甲氧基硅烷（MAPTMS），α，α 二乙氧基苯乙酮（DEAP），另一种是光敏硅胶组合物。
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公开(公告)号：US08840648B2
公开(公告)日：2014-09-23
申请号：US12751944
申请日：2010-03-31
Applicant: Yang-Hwei Tsuang , Chang Jung Chiang , Shan-Chang Chueh , Chun-Jen Liao , Chung-Nun Chen , Ya-Jen Yu
Inventor： Yang-Hwei Tsuang , Chang Jung Chiang , Shan-Chang Chueh , Chun-Jen Liao , Chung-Nun Chen , Ya-Jen Yu
CPC classification number: A61F2/442 , A61F2/4611 , A61F2002/2835 , A61F2002/3052 , A61F2002/3055 , A61F2002/30579 , A61F2002/4475 , A61F2002/448 , A61F2002/4485 , A61F2002/4623 , A61F2002/4627 , A61F2002/4628 , A61F2002/4629 , A61F2220/0025 , A61F2310/00221 , A61F2310/00293 , A61F2310/00365 , A61F2310/00383
Abstract: A spinal cage is provided to be implanted in an intervertebral disc space. The spinal cage includes a first segment and a second segment movably connected with each other. The first segment is slidable with respect to the second segment, so as to elongate the spinal cage from a retracted state to an extended state.
Abstract translation: 提供脊柱笼以植入椎间盘空间。 脊柱笼包括彼此可移动地连接的第一段和第二段。 第一段可相对于第二段滑动，从而将脊柱笼从缩回状态延伸至延伸状态。
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公开(公告)号：US08435271B2
公开(公告)日：2013-05-07
申请号：US13231924
申请日：2011-09-13
Applicant: Ching-Chuan Jiang , Shan-Chang Chueh , Ting-Hui Chiu , Chun-Jen Liao , Yi-Hung Lin , Ya-Jen Yu , I-Fan Chiu
Inventor： Ching-Chuan Jiang , Shan-Chang Chueh , Ting-Hui Chiu , Chun-Jen Liao , Yi-Hung Lin , Ya-Jen Yu , I-Fan Chiu
IPC: A61B17/03
CPC classification number: A61F2/0811 , A61B17/8875 , A61F2/0805 , A61F2002/0829 , A61F2002/0835 , A61F2002/0858 , A61F2002/0888
Abstract: A device for fixing soft tissue. A sleeve is detachably connected to a self-drilling tapping screw, moving and rotating the self-drilling tapping screw. A guide bar is detachably connected to the self-drilling tapping screw and fit in the sleeve. A fixing pin is fit in a washer and connected to the self-drilling tapping screw. The guide bar is detachably fit in the fixing pin. The fixing pin abuts the washer and the self-drilling tapping screw.
Abstract translation: 用于固定软组织的装置。 套筒可拆卸地连接到自钻自攻螺钉，移动和旋转自钻自攻螺钉。 引导杆可拆卸地连接到自钻自攻螺钉并且装配在套筒中。 固定销安装在垫圈中，并与自钻自攻螺钉相连。 导杆可拆卸地安装在固定销中。 固定销与垫圈和自钻自攻螺钉相接。
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Patent Agency Ranking
公开(公告)号：US08129188B2
公开(公告)日：2012-03-06
申请号：US12155785
申请日：2008-06-10
Applicant: Ming-Cheng Shih , Chin-Fu Chen , Rung-Jiun Gau , Yu-Shih Weng , Ya-Jen Yu , Shao-Jen Yeh
Inventor： Ming-Cheng Shih , Chin-Fu Chen , Rung-Jiun Gau , Yu-Shih Weng , Ya-Jen Yu , Shao-Jen Yeh
CPC classification number: C12M25/14
Abstract: A cell culture apparatus and a method for fabricating the cell culture apparatus are disclosed, the method comprises forming at least one fillister on a biomaterial composite layer by photolithography, wherein the biomaterial composite layer contains two gel materials. One is a bio-compatible hydrogel composition having various weight ratio of: 2-hydroxyethylmathacrylate (HEMA), bisphenol A and glycidyl methacrylate (bis-GMA), triethylene glycol dimethacrylate (TEGDMA), r-methacryloxypropyl trimethoxysilane (MAPTMS), α,α-diethoxyacetophenone (DEAP), and the other one is a photo-sensitive silica gel composition.
Abstract translation: 公开了一种细胞培养装置和细胞培养装置的制造方法，该方法包括通过光刻法在生物材料复合层上形成至少一个填充物，其中生物材料复合层含有两种凝胶材料。 一种是具有以下重要比例的生物相容性水凝胶组合物：2-羟乙基甲基丙烯酸酯（HEMA），双酚A和甲基丙烯酸缩水甘油酯（双-GMA），三乙二醇二甲基丙烯酸酯（TEGDMA），γ-甲基丙烯酰氧基丙基三甲氧基硅烷（MAPTMS），α，α 二乙氧基苯乙酮（DEAP），另一种是光敏硅胶组合物。
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公开(公告)号：US07884142B2
公开(公告)日：2011-02-08
申请号：US12395495
申请日：2009-02-27
Applicant: Ya-Jen Yu , Chin-Fu Chen , Tsai-Yu Lin , Shao-Jen Yeh , Shian-Yih Wang , Po-Liang Lai
Inventor： Ya-Jen Yu , Chin-Fu Chen , Tsai-Yu Lin , Shao-Jen Yeh , Shian-Yih Wang , Po-Liang Lai
CPC classification number: A61L24/0042 , A61L24/046 , C08G63/664 , C08G69/14 , C08G69/42 , C08L67/04 , C08L71/02
Abstract: The disclosed is a biodegradable copolymer, an amphiphilic diblock copolymer, composed of a hydrophilic segment and a hydrophobic segment. The hydrophilic segment is an endcapped PEG or derivatives thereof. The hydrophilic segment is a random polymer polymerized of lactone or cyclic C3-C6 molecule and lactic acid/glycolic acid. There is no coupling agent between the hydrophilic and hydrophobic segments, and the biodegradable copolymer is formed by one-pot ring-opening polymerization. The biodegradable copolymer can be dissolved in water to form a thermosensitive material having a phase transfer temperature of 25 to 50° C., thereby being applied to biological activity factor delivery, tissue engineering, cell culture and biological glue.
Abstract translation: 所公开的是由亲水链段和疏水链段组成的可生物降解的共聚物，两亲二嵌段共聚物。 亲水片段是封端的PEG或其衍生物。 亲水段是内酯或环状C 3 -C 6分子和乳酸/乙醇酸聚合的无规聚合物。 亲水和疏水链段之间没有偶联剂，生物降解共聚物是通过一锅开环聚合形成的。 可生物降解的共聚物可以溶解在水中以形成相转移温度为25-50℃的热敏材料，从而适用于生物活性因子递送，组织工程，细胞培养和生物胶。
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公开(公告)号：US20100256764A1
公开(公告)日：2010-10-07
申请号：US12751944
申请日：2010-03-31
Applicant: Yang-Hwei Tsuang , Chang Jung Chiang , Shan-Chang Chueh , Chun-Jen Liao , Chung-Nun Chen , Ya-Jen Yu
Inventor： Yang-Hwei Tsuang , Chang Jung Chiang , Shan-Chang Chueh , Chun-Jen Liao , Chung-Nun Chen , Ya-Jen Yu
IPC: A61F2/44
CPC classification number: A61F2/442 , A61F2/4611 , A61F2002/2835 , A61F2002/3052 , A61F2002/3055 , A61F2002/30579 , A61F2002/4475 , A61F2002/448 , A61F2002/4485 , A61F2002/4623 , A61F2002/4627 , A61F2002/4628 , A61F2002/4629 , A61F2220/0025 , A61F2310/00221 , A61F2310/00293 , A61F2310/00365 , A61F2310/00383
Abstract: A spinal cage is provided to be implanted in an intervertebral disc space. The spinal cage includes a first segment and a second segment movably connected with each other. The first segment is slidable with respect to the second segment, so as to elongate the spinal cage from a retracted state to an extended state.
Abstract translation: 提供脊柱笼以植入椎间盘空间。 脊柱笼包括彼此可移动地连接的第一段和第二段。 第一段可相对于第二段滑动，从而将脊柱笼从缩回状态延伸至延伸状态。
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公开(公告)号：US07749761B2
公开(公告)日：2010-07-06
申请号：US11446207
申请日：2006-06-05
Applicant: Ming-Cheng Shih , Chin-Fu Chen , Rung-Jiun Gau , Yu-Shih Weng , Ya-Jen Yu , Shao-Jen Yeh
Inventor： Ming-Cheng Shih , Chin-Fu Chen , Rung-Jiun Gau , Yu-Shih Weng , Ya-Jen Yu , Shao-Jen Yeh
CPC classification number: C12M25/14
Abstract: A cell culture apparatus and a method for fabricating the cell culture apparatus are disclosed, the method comprises forming at least one fillister on a biomaterial composite layer by photolithography, wherein the biomaterial composite layer contains two gel materials. One is a bio-compatible hydrogel composition having various weight ratio of: 2-hydroxyethylmathacrylate (HEMA), bisphenolA and glycidyl methacrylate (bis-GMA), triethylene glycol dimethacrylate (TEGDMA), r-methacryloxypropyl trimethoxysilane (MAPTMS), α,α-diethoxyacetophenone (DEAP), and the other one is a photo-sensitive silica gel composition.
Abstract translation: 公开了一种细胞培养装置和细胞培养装置的制造方法，该方法包括通过光刻法在生物材料复合层上形成至少一个填充物，其中生物材料复合层含有两种凝胶材料。 一种是具有以下重量比的生物相容性水凝胶组合物：2-羟乙基甲基丙烯酸酯（HEMA），双酚A和甲基丙烯酸缩水甘油酯（双-GMA），三乙二醇二甲基丙烯酸酯（TEGDMA），γ-甲基丙烯酰氧基丙基三甲氧基硅烷（MAPTMS），α， 二乙氧基苯乙酮（DEAP），另一种是光敏硅胶组合物。
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公开(公告)号：US20070072288A1
公开(公告)日：2007-03-29
申请号：US11446207
申请日：2006-06-05
Applicant: Ming-Cheng Shih , Yu-Shih Weng , Chin-Fu Chen , Rung-Jiun Gau , Ya-Jen Yu , Shao-Jen Yeh
Inventor： Ming-Cheng Shih , Yu-Shih Weng , Chin-Fu Chen , Rung-Jiun Gau , Ya-Jen Yu , Shao-Jen Yeh
IPC: C12M3/00
CPC classification number: C12M25/14
Abstract: A cell culture apparatus and a method for fabricating the cell culture apparatus are disclosed, the method comprises forming at least one fillister on a biomaterial composite layer by photolithography, wherein the biomaterial composite layer contains two gel materials. One is a bio-compatible hydrogel composition having various weight ratio of:2-hydroxyethylmathacrylate(HEMA),bisphenolA and glycidyl methacrylate (bis-GMA), triethylene glycol dimethacrylate (TEGDMA), r-methacryloxypropyl trimethoxysilane (MAPTMS), α,α-diethoxyacetophenone (DEAP), and the other one is a photo-sensitive silica gel composition.
Abstract translation: 公开了一种细胞培养装置和细胞培养装置的制造方法，该方法包括通过光刻法在生物材料复合层上形成至少一个填充物，其中生物材料复合层含有两种凝胶材料。 一种是具有以下重量比的生物相容性水凝胶组合物：2-羟乙基甲基丙烯酸酯（HEMA），双酚A和甲基丙烯酸缩水甘油酯（双-GMA），三乙二醇二甲基丙烯酸酯（TEGDMA），γ-甲基丙烯酰氧基丙基三甲氧基硅烷（MAPTMS），α， 二乙氧基苯乙酮（DEAP），另一种是光敏硅胶组合物。
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