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11.发明申请公开(公告)号：US20150157771A1
公开(公告)日：2015-06-11
申请号：US14624063
申请日：2015-02-17
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Syed F.A. Hossainy , O. Mikael Trollsas , Lothar W. Kleiner
CPC classification number: A61L31/148 , A61F2/82 , A61L27/34 , A61L27/58 , A61L29/085 , A61L29/148 , A61L31/048 , A61L31/06 , A61L31/10 , A61L31/16 , A61L2300/602 , C08L1/286 , C08L5/08 , C08L89/00 , C09D101/286 , C09D105/08 , C09D189/00
Abstract: The present invention provides an implantable device having a biosoluble coating comprising a polyelectrolyte and a counterion and the methods of making and using the same.
Abstract translation: 本发明提供了具有包含聚电解质和抗衡离子的生物可溶性涂层的可植入装置及其制备和使用方法。
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公开(公告)号：US20150147402A1
公开(公告)日：2015-05-28
申请号：US14542983
申请日：2014-11-17
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： O. Mikael Trollsas , Michael H. Ngo , David J. Sherman , Syed F.A. Hossainy
IPC: A61K9/50 , A61K31/436
CPC classification number: A61L31/10 , A61K9/5031 , A61K9/5089 , A61K31/33 , A61K31/436 , A61K31/497 , A61K31/56 , A61K38/13 , A61K38/446 , A61K45/06 , A61K47/34 , A61L27/34 , A61L31/148 , A61L31/16 , A61L2300/416 , A61L2300/602 , A61L2300/606 , A61L2420/02 , C08L71/02 , C08L67/04
Abstract: The present invention provides an implantable device having a coating including a slow dissolving polymer or material and the methods of making and using the same.
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公开(公告)号：US20150290363A1
公开(公告)日：2015-10-15
申请号：US14251536
申请日：2014-04-11
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Stephen D. Pacetti , O. Mikael Trollsas , Alexander J. Sheehy
CPC classification number: A61L31/10 , A61L31/08 , A61L31/16 , A61L33/128 , A61L2300/252 , A61L2300/42 , A61L2420/02 , C08L89/00
Abstract: Coatings for medical devices, the coatings including albumin, the methods of forming the coatings, and the coated medical devices are disclosed. In preferred embodiments the medical device is a bioabsorbable stent. The albumin coating layer improves the thromboresistance of the device.
Abstract translation: 公开了用于医疗装置的涂层，包括白蛋白的涂层，形成涂层的方法和涂覆的医疗装置。 在优选实施例中，医疗装置是生物可吸收支架。 白蛋白涂层改善了该装置的血栓阻力。
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公开(公告)号：US09067002B2
公开(公告)日：2015-06-30
申请号：US14185699
申请日：2014-02-20
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： O. Mikael Trollsas , Lothar W. Kleiner , Syed F. A. Hossainy
CPC classification number: A61L31/10 , A61L27/34 , A61L31/148 , A61L31/16 , A61L2300/416 , A61L2400/18 , A61L2420/08 , C08L67/04
Abstract: An aliphatic polyester polymer for stent coating is described.
Abstract translation: 描述了用于支架涂层的脂族聚酯聚合物。
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公开(公告)号：US09066992B2
公开(公告)日：2015-06-30
申请号：US13903773
申请日：2013-05-28
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： John J. Stankus , O. Mikael Trollsas , Michael H. Ngo
CPC classification number: A61L27/18 , A61L27/34 , A61L27/54 , A61L2400/16 , C08G2230/00 , C08G2280/00 , C08L75/04
Abstract: The present invention is directed to polymeric compositions comprising a biodegradable copolymer that possesses shape-memory properties and implantable devices (e.g., drug-delivery stents) formed of materials (e.g., a coating) containing such compositions. The polymeric compositions can also contain at least one non-fouling moiety, at least additional biocompatible polymer, at least one biobeneficial material, at least one bioactive agent, or a combination thereof. The polymeric compositions are formulated to possess good mechanical, physical and biological properties. Moreover, implantable devices formed of materials comprising such compositions can be delivered to the treatment site in a conveniently compressed size and then can expand to dimensions appropriate for their medical functions.
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Patent Agency Ranking
16.发明申请Block Copolymer Comprising at least one Polyester Block and at least one Poly(ethylene glycol) Block 审中-公开嵌段共聚物包含至少一个聚酯嵌段和至少一个聚（乙二醇）嵌段公开(公告)号：US20150174300A1
公开(公告)日：2015-06-25
申请号：US14580101
申请日：2014-12-22
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： O. Mikael Trollsas , Michael H. Ngo , Syed F. A. Hossainy , David J. Sherman
CPC classification number: A61L31/10 , A61L31/047 , A61L31/06 , A61L31/148 , A61L31/16 , A61L2300/416 , A61L2300/606 , C08L71/02 , C08L67/04
Abstract: The present invention provides a block copolymer for a coating on an implantable device for controlling release of drug and methods of making and using the same.
Abstract translation: 本发明提供了用于控制药物释放的可植入装置上的涂层的嵌段共聚物及其制备和使用方法。
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公开(公告)号：US20140186417A1
公开(公告)日：2014-07-03
申请号：US14185699
申请日：2014-02-20
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： O. Mikael Trollsas , Lothar W. Kleiner , Syed F.A. Hossainy
CPC classification number: A61L31/10 , A61L27/34 , A61L31/148 , A61L31/16 , A61L2300/416 , A61L2400/18 , A61L2420/08 , C08L67/04
Abstract: An aliphatic polyester polymer for stent coating is described.
Abstract translation: 描述了用于支架涂层的脂族聚酯聚合物。
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公开(公告)号：US20140010858A1
公开(公告)日：2014-01-09
申请号：US13903773
申请日：2013-05-28
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： John J. Stankus , O. Mikael Trollsas , Michael H. Ngo
CPC classification number: A61L27/18 , A61L27/34 , A61L27/54 , A61L2400/16 , C08G2230/00 , C08G2280/00 , C08L75/04
Abstract: The present invention is directed to polymeric compositions comprising a biodegradable copolymer that possesses shape-memory properties and implantable devices (e.g., drug-delivery stents) formed of materials (e.g., a coating) containing such compositions. The polymeric compositions can also contain at least one non-fouling moiety, at least additional biocompatible polymer, at least one biobeneficial material, at least one bioactive agent, or a combination thereof. The polymeric compositions are formulated to possess good mechanical, physical and biological properties. Moreover, implantable devices formed of materials comprising such compositions can be delivered to the treatment site in a conveniently compressed size and then can expand to dimensions appropriate for their medical functions.
Abstract translation: 本发明涉及包含具有形状记忆特性的可生物降解的共聚物和由含有这种组合物的材料（例如涂层）形成的可植入装置（例如药物递送支架）的聚合物组合物。 聚合物组合物还可含有至少一种非结垢部分，至少另外的生物相容性聚合物，至少一种生物有益材料，至少一种生物活性剂或其组合。 将聚合物组合物配制成具有良好的机械，物理和生物学特性。 此外，由包含这种组合物的材料形成的可植入装置可以以方便的压缩尺寸输送到治疗部位，然后可扩大到适于其医疗功能的尺寸。
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公开(公告)号：US09622891B2
公开(公告)日：2017-04-18
申请号：US14687843
申请日：2015-04-15
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Benjamyn Serna , Michael Huy Ngo , Syed F. A. Hossainy , O. Mikael Trollsas
CPC classification number: A61F2/95 , A61F2210/0076 , A61F2230/0063 , A61F2240/001 , A61F2250/0067 , A61L2420/02 , B05D1/002 , B05D1/38 , B05D3/10 , B05D3/12
Abstract: Embodiments of the present invention encompass methods of forming coatings, particularly coatings for medical devices, and more particularly, for braided or woven medical devices. Embodiments of the present invention encompass the coatings and the coated devices. The coatings may include a polymer and optionally a therapeutic agent.
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公开(公告)号：US09474834B2
公开(公告)日：2016-10-25
申请号：US14251536
申请日：2014-04-11
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Stephen D. Pacetti , O. Mikael Trollsas , Alexander J. Sheehy
CPC classification number: A61L31/10 , A61L31/08 , A61L31/16 , A61L33/128 , A61L2300/252 , A61L2300/42 , A61L2420/02 , C08L89/00
Abstract: Coatings for medical devices, the coatings including albumin, the methods of forming the coatings, and the coated medical devices are disclosed. In preferred embodiments the medical device is a bioabsorbable stent. The albumin coating layer improves the thromboresistance of the device.
Abstract translation: 公开了用于医疗装置的涂层，包括白蛋白的涂层，形成涂层的方法和涂覆的医疗装置。 在优选实施例中，医疗装置是生物可吸收支架。 白蛋白涂层改善了该装置的血栓阻力。
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