公开(公告)号：US08920832B2

公开(公告)日：2014-12-30

申请号：US13249120

申请日：2011-09-29

申请人： Hiroshi Kikuchi ,  Hideo Kobayashi ,  Kouichi Hashimoto ,  Ayako Iijima ,  Daigo Asano ,  Junko Yasuda

发明人： Hiroshi Kikuchi ,  Hideo Kobayashi ,  Kouichi Hashimoto ,  Ayako Iijima ,  Daigo Asano ,  Junko Yasuda

IPC分类号： A61K31/7088 ,  A61K48/00

CPC分类号： A61K31/7088 ,  A61K48/0025

摘要： The invention provides a nucleic-acid-transfecting composition which exhibits low cytotoxicity, which facilitates an effective nucleic acid transfection into a cell, and which improves expression of the nucleic acid in the cell.The composition for transfecting a nucleic acid into a cell, contains a di(C12-16 alkyl)dimethylammonium halide and a phospholipid.

摘要翻译： 本发明提供了一种显示低细胞毒性的核酸转染组合物，其有利于有效的核酸转染到细胞中，并且其改善细胞中核酸的表达。 用于将核酸转染入细胞的组合物含有二（C 12-16烷基）二甲基卤化铵和磷脂。

公开(公告)号：US08829000B2

公开(公告)日：2014-09-09

申请号：US13617683

申请日：2012-09-14

申请人： Makoto Okada ,  Shuichiro Sato ,  Kenji Kawade ,  Kotaro Gotanda ,  Atsushi Shinbo ,  Youichi Nakano ,  Hideo Kobayashi

发明人： Makoto Okada ,  Shuichiro Sato ,  Kenji Kawade ,  Kotaro Gotanda ,  Atsushi Shinbo ,  Youichi Nakano ,  Hideo Kobayashi

IPC分类号： A61K31/4985 ,  C07D487/04 ,  C07D487/14

CPC分类号： C07D487/04 ,  C07D487/14

摘要： The invention discloses quinoxaline derivatives or salts thereof having PDE9-inhibiting activity and being useful as treating agent of dysuria and the like, which are represented by the formula (I) in the formula, R1 and R2 each independently stands for hydrogen, halogen, alkyl, alkoxy, acyl, amino and the like, R3 stands for alkyl, aryl, saturated carbocyclic group, saturated heterocyclic group, acyl and the like, R4 stands for hydrogen, hydroxy, alkyl or amino, R5 and R8 each independently stands for hydrogen, halogen, alkyl, alkenyl, alkoxy, cyano or nitro, R6 and R7 each independently stands for hydrogen, halogen, alkyl, alkenyl, alkynyl, alkoxy, cyano, amino, carbocyclic group, heterocyclic group, COR9 or SO2R9, R9 stands for hydrogen, hydroxy, alkyl, amino, pyrrolidin-1-yl, piperidin-1-yl, pyperazin-1-yl or the like, X stands for S or O, and A1, A2 and A3 each independently stands for N or C.

摘要翻译： 本发明公开了具有PDE9抑制活性的喹喔啉衍生物或其盐，可用作式（I）所示的排尿困难等的治疗剂，R 1和R 2各自独立地表示氢，卤素，烷基 烷氧基，酰基，氨基等，R3代表烷基，芳基，饱和碳环基，饱和杂环基，酰基等，R4代表氢，羟基，烷基或氨基，R5和R8各自独立代表氢， 卤素，烷基，烯基，烷氧基，氰基或硝基，R6和R7各自独立地代表氢，卤素，烷基，烯基，炔基，烷氧基，氰基，氨基，碳环基，杂环基，COR9或SO2R9，R9代表氢， 羟基，烷基，氨基，吡咯烷-1-基，哌啶-1-基，哒嗪-1-基等，X表示S或O，并且，A1，A2和A3各自独立地表示N或C.

公开(公告)号：US08683963B2

公开(公告)日：2014-04-01

申请号：US13376880

申请日：2009-06-08

申请人： Hideo Kobayashi ,  Toshihisa Sugiyama ,  Kenichi Yamada ,  Shusaku Sugamoto ,  Bunki Kawano

发明人： Hideo Kobayashi ,  Toshihisa Sugiyama ,  Kenichi Yamada ,  Shusaku Sugamoto ,  Bunki Kawano

IPC分类号： F01P1/04

CPC分类号： F01M1/16 ,  F01M1/08 ,  F01P3/06

摘要： A hydraulic control device is equipped with an oil jet that injects oil to a piston, an oil gallery through which oil injected by the oil jet and oil supplied to a lubrication part of an engine pass, an oil pump that pumps oil to the oil gallery, and a switching valve that is provided on an oil jet passage connecting the oil gallery and the oil jet together and leads oil supplied from the oil gallery to either the oil jet or an oil pan disposed at an upstream side of the oil pump. An ECU controls the switching valve on the basis of an engine speed and an engine cooling water temperature.

摘要翻译： 液压控制装置配备有将油喷射到活塞的油喷射器，通过油喷射的油被供应到发动机通过的润滑部分的油的油库，将油泵送到油库的油泵 以及切换阀，其设置在将油路和油喷射连接在一起的油喷射通路上，并将从油路供给的油引导到设置在油泵的上游侧的油喷射或油盘。 ECU根据发动机转速和发动机冷却水温度控制切换阀。

公开(公告)号：US08552357B2

公开(公告)日：2013-10-08

申请号：US13040172

申请日：2011-03-03

申请人： Hideo Kobayashi

发明人： Hideo Kobayashi

IPC分类号： H01J40/14

CPC分类号： G01J1/42 ,  G01J1/18 ,  G01J1/44 ,  H01L31/02019 ,  H01L31/035272 ,  H01L31/103 ,  H03F3/08

摘要： An apparatus includes a first photoelectric conversion element configured to convert light into a current by a photoelectric conversion, a first current amplification unit configured to amplify the current, a first current monitoring unit configured to monitor the amplified current amplified and output a monitor signal, and a first bias voltage setting unit configured to gain the monitor signal by a factor less than 1 and apply a reverse bias voltage to the first photoelectric conversion element according to the gained monitor signal.

摘要翻译： 一种装置，包括被配置为通过光电转换将光转换为电流的第一光电转换元件，被配置为放大电流的第一电流放大单元，被配置为监视放大的放大电流并输出监视信号的第一电流监视单元，以及 第一偏置电压设定单元，被配置为以小于1的因子获得所述监视信号，并且根据所获得的监视信号向所述第一光电转换元件施加反向偏置电压。

公开(公告)号：US20130078578A1

公开(公告)日：2013-03-28

申请号：US13638249

申请日：2011-03-28

申请人： Hiromasa Iyama ,  Hideo Kobayashi

发明人： Hiromasa Iyama ,  Hideo Kobayashi

IPC分类号： G03F7/32

CPC分类号： G03F7/325 ,  Y10S430/143

摘要： The disclosed resist developer is used when developing by irradiating an energy beam onto a resist layer containing a polymer of α-chloromethacrylate and α-methylstyrene for rendering or exposure, and contains a fluorocarbon-containing solvent (A) and an alcohol solvent (B), the latter of which has higher solubility relative to the resist layer than the former.

摘要翻译： 通过将能量束照射到含有α-甲基丙烯酸甲酯和α-甲基苯乙烯的聚合物的抗蚀层上进行显影或曝光而使用本发明的抗蚀剂显影剂，并含有含氟碳的溶剂（A）和醇溶剂（B） ，后者相对于抗蚀剂层的溶解度高于前者。

公开(公告)号：US20130056807A1

公开(公告)日：2013-03-07

申请号：US13595520

申请日：2012-08-27

申请人： Hideo Kobayashi ,  Tetsunobu Kochi

发明人： Hideo Kobayashi ,  Tetsunobu Kochi

IPC分类号： H01L31/102 ,  H01L31/113 ,  H01L31/11

CPC分类号： H01L31/03529 ,  H01L27/14647 ,  H01L31/103 ,  Y02E10/50

摘要： A photoelectric converting apparatus has first and third semiconductor layers of a first conductivity type which respectively output signals obtained by photoelectric conversion, and second and fourth semiconductor layers of a second conductivity type supplied with potentials from a potential supplying unit. In the photoelectric converting apparatus, the first, second, third and fourth semiconductor layers are arranged in sequence, the second and fourth semiconductor layers are electrically separated from each other, and the potential to be supplied to the second semiconductor layer and the potential to be supplied to the fourth semiconductor layer are controlled independently from each other.

摘要翻译： 光电转换装置具有分别输出通过光电转换获得的信号的第一导电类型的第一和第三半导体层以及从电位供给单元提供电位的第二和第四半导体层。 在光电转换装置中，第一，第二，第三和第四半导体层依次布置，第二和第四半导体层彼此电分离，并且提供给第二半导体层的电位和潜在的 被提供给第四半导体层的第一半导体层彼此独立地被控制。

公开(公告)号：US08325259B2

公开(公告)日：2012-12-04

申请号：US12628422

申请日：2009-12-01

申请人： Hideo Kobayashi ,  Tomohisa Kinugasa

发明人： Hideo Kobayashi ,  Tomohisa Kinugasa

IPC分类号： H04N3/14 ,  H04N5/335

CPC分类号： H01L31/02005 ,  G01J1/44 ,  H01L27/1446 ,  H01L27/14647 ,  H01L31/102

摘要： A photoelectric conversion apparatus includes: a first photoelectric conversion element generating a current by photoelectric conversion; a first current amplifying element for amplifying the current generated by the first photoelectric conversion element; a first detecting unit for detecting a reverse bias voltage value of the first photoelectric conversion element; and a first setting unit for setting the reverse bias voltage value of the first photoelectric conversion element at a first normal value based on a result of the detection by the first detecting unit, wherein the first normal value is larger than a depleting voltage of the first photoelectric conversion element.

摘要翻译： 一种光电转换装置包括：通过光电转换产生电流的第一光电转换元件; 第一电流放大元件，用于放大由第一光电转换元件产生的电流; 第一检测单元，用于检测第一光电转换元件的反向偏置电压值; 以及第一设定单元，用于基于第一检测单元的检测结果，将第一光电转换元件的反向偏置电压值设定在第一正常值，其中第一正常值大于第一正常值的消耗电压 光电转换元件。

公开(公告)号：US08161920B2

公开(公告)日：2012-04-24

申请号：US12223858

申请日：2007-06-04

申请人： Kunihiko Hayashi ,  Hideo Kobayashi ,  Katuhiko Arisawa ,  Yoshio Yamashita ,  Kenichi Yamada

发明人： Kunihiko Hayashi ,  Hideo Kobayashi ,  Katuhiko Arisawa ,  Yoshio Yamashita ,  Kenichi Yamada

IPC分类号： F01P11/02

CPC分类号： F28D20/028 ,  B60H1/00492 ,  F01P2003/021 ,  F01P2011/205 ,  F01P2025/31 ,  F01P2037/02 ,  F02N19/10 ,  Y02E60/145

摘要： In the cylinder block of an engine including a heat storage apparatus, a water jacket is formed between a cylinder bore wall that forms a cylinder bore and a cylinder block outer wall. An actuator is installed on the cylinder block outer wall. A container is housed in the water jacket. A coolant temperature sensor is installed on the upper portion of the container. An ECU determines the state of a heat storage agent in the container and the state of the container, based on information on the temperature of coolant determined by the coolant temperature sensor.

摘要翻译： 在包括蓄热装置的发动机的气缸体中，在形成气缸孔的气缸孔壁和气缸体外壁之间形成水套。 执行器安装在气缸体外壁上。 一个容器装在水套里。 冷却剂温度传感器安装在容器的上部。 基于由冷却剂温度传感器确定的冷却剂的温度的信息，ECU确定容器中的蓄热剂的状态和容器的状态。

公开(公告)号：USD649574S1

公开(公告)日：2011-11-29

申请号：US29351207

申请日：2009-12-02

申请人： Hideo Kobayashi

设计人： Hideo Kobayashi

公开(公告)号：US08066100B2

公开(公告)日：2011-11-29

申请号：US11664601

申请日：2005-10-05

申请人： Taiichi Mori ,  Hideo Kobayashi ,  Katuhiko Arisawa ,  Kenichi Yamada ,  Yoshio Yamashita ,  Kunihiko Hayashi

发明人： Taiichi Mori ,  Hideo Kobayashi ,  Katuhiko Arisawa ,  Kenichi Yamada ,  Yoshio Yamashita ,  Kunihiko Hayashi

IPC分类号： F16N31/00

CPC分类号： F01M11/0004 ,  F01M5/007 ,  F01M2011/0037 ,  F01M2011/0045 ,  F01M2011/007 ,  Y10T137/7404 ,  Y10T137/7436

摘要： An oil pan is provided with an oil pan separator that partitions a first chamber that communicates with a moving part inside a cylinder block and a second chamber outside the first chamber. A communicating hole is provided to a bottom panel of the oil pan separator. The communicating hole is shielded from a strainer.

摘要翻译： 油盘设置有油盘分离器，其分隔与气缸体内的运动部分连通的第一室和在第一室外的第二室。 连通孔设置在油底壳分离器的底板上。 连通孔与过滤器屏蔽。