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公开(公告)号:US07867749B2
公开(公告)日:2011-01-11
申请号:US11326080
申请日:2006-01-05
申请人: Deryck J. Williams , Merry B. McLaird , Michelle Coutu Hresko , Anita M. Frevert-Thompson , Ronald E. Worthington , Andrew P. Kloek , Jennifer A. Davila-Aponte , John D. Bradley , Siqun Xu
发明人: Deryck J. Williams , Merry B. McLaird , Michelle Coutu Hresko , Anita M. Frevert-Thompson , Ronald E. Worthington , Andrew P. Kloek , Jennifer A. Davila-Aponte , John D. Bradley , Siqun Xu
CPC分类号: C12N9/1007
摘要: Nucleic acid molecules from nematodes encoding phosphoethanolamine n-methyltransferase polypeptides are described. PEAMT-like polypeptide sequences are also provided, as are vectors, host cells, and recombinant methods for production of PEAMT-like nucleotides and polypeptides. Also described are screening methods for identifying inhibitors and/or activators, as well as methods for antibody production.
摘要翻译: 描述了编码磷酸乙醇胺正甲基转移酶多肽的线虫的核酸分子。 还提供了PEAMT样多肽序列,载体,宿主细胞和用于产生PEAMT样核苷酸和多肽的重组方法也是如此。 还描述了用于鉴定抑制剂和/或激活剂的筛选方法以及用于抗体生产的方法。
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公开(公告)号:US20090123986A1
公开(公告)日:2009-05-14
申请号:US12260071
申请日:2008-10-28
申请人: Deryck J. Williams , Merry B. McLaird , Michelle Coutu Hresko , Anita M. Frevert , Ronald E. Worthington , Andrew P. Kloek , Jennifer A. Davila-Aponte , John D. Bradley , Siqun Xu
发明人: Deryck J. Williams , Merry B. McLaird , Michelle Coutu Hresko , Anita M. Frevert , Ronald E. Worthington , Andrew P. Kloek , Jennifer A. Davila-Aponte , John D. Bradley , Siqun Xu
IPC分类号: C12N9/10
CPC分类号: C12N9/1007
摘要: Nucleic acid molecules from nematodes encoding phosphoethanolamine n-methyltransferase polypeptides are described. PEAMT-like polypeptide sequences are also provided, as are vectors, host cells, and recombinant methods for production of PEAMT-like nucleotides and polypeptides. Also described are screening methods for identifying inhibitors and/or activators, as well as methods for antibody production.
摘要翻译: 描述了编码磷酸乙醇胺正甲基转移酶多肽的线虫的核酸分子。 还提供了PEAMT样多肽序列,载体,宿主细胞和用于产生PEAMT样核苷酸和多肽的重组方法也是如此。 还描述了用于鉴定抑制剂和/或激活剂的筛选方法以及用于抗体生产的方法。
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公开(公告)号:US20080227955A1
公开(公告)日:2008-09-18
申请号:US12042297
申请日:2008-03-04
申请人: Michelle Coutu Hresko , Merry B. Mclaird , Deryck J. Williams , Anita M. Frevert , Brandi Chiapelli , Catherine Baublite , Andrew P. Kloek , Jennifer A. Davila-Aponte , John D. Bradley , Siqun Xu
发明人: Michelle Coutu Hresko , Merry B. Mclaird , Deryck J. Williams , Anita M. Frevert , Brandi Chiapelli , Catherine Baublite , Andrew P. Kloek , Jennifer A. Davila-Aponte , John D. Bradley , Siqun Xu
IPC分类号: C07K14/435
CPC分类号: C07K14/705
摘要: Nucleic acid molecules from nematodes encoding PAN and ZP domain containing receptor polypeptides are described. PANZP polypeptide sequences are also provided, as are vectors, host cells, and recombinant methods for production of PANZP nucleotides and polypeptides. Also described are screening methods for identifying inhibitors and/or activators, as well as methods for antibody production.
摘要翻译: 描述了编码含有PAN和ZP结构域的受体多肽的线虫的核酸分子。 还提供PANZP多肽序列,载体,宿主细胞以及用于产生PANZP核苷酸和多肽的重组方法。 还描述了用于鉴定抑制剂和/或激活剂的筛选方法以及用于抗体生产的方法。
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公开(公告)号:US20080227193A1
公开(公告)日:2008-09-18
申请号:US12061072
申请日:2008-04-02
申请人: Andrew P. Kloek , Deryck J. Williams , Merry B. McLaird , John D. Bradley , Jennifer A. Davila-Aponte , Siqun Xu , Anita M. Frevert
发明人: Andrew P. Kloek , Deryck J. Williams , Merry B. McLaird , John D. Bradley , Jennifer A. Davila-Aponte , Siqun Xu , Anita M. Frevert
CPC分类号: C12N9/0083 , C12N15/8247 , C12N15/8285 , G01N33/573 , G01N2333/4353 , Y02A40/164
摘要: Nucleic acid molecules from nematodes encoding fatty acid desaturase polypeptides are described. Fatty acid desaturase-like polypeptide sequences are also provided, as are vectors, host cells, and recombinant methods for production of fatty acid desaturase-like nucleotides and polypeptides. Also described are screening methods for identifying inhibitors and/or activators of fatty acid desaturase-like polypeptides, as well as methods for antibody production.
摘要翻译: 描述了编码脂肪酸去饱和酶多肽的线虫的核酸分子。 还提供了脂肪酸去饱和酶样多肽序列,以及用于产生脂肪酸去饱和酶样核苷酸和多肽的载体,宿主细胞和重组方法。 还描述了用于鉴定脂肪酸去饱和酶样多肽的抑制剂和/或激活剂的筛选方法以及用于抗体生产的方法。
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公开(公告)号:US07250500B2
公开(公告)日:2007-07-31
申请号:US11191374
申请日:2005-07-28
申请人: Michelle Coutu Hresko , Merry B. McLaird , Deryck J. Williams , Anita M. Frevert , Brandi Chiapelli , Catherine Baublite , Andrew P. Kloek , Jennifer A. Davila-Aponte , John D. Bradley , Siqun Xu
发明人: Michelle Coutu Hresko , Merry B. McLaird , Deryck J. Williams , Anita M. Frevert , Brandi Chiapelli , Catherine Baublite , Andrew P. Kloek , Jennifer A. Davila-Aponte , John D. Bradley , Siqun Xu
CPC分类号: C07K14/705
摘要: Nucleic acid molecules from nematodes encoding PAN and ZP domain containing receptor polypeptides are described. PANZP polypeptide sequences are also provided, as are vectors, host cells, and recombinant methods for production of PANZP nucleotides and polypeptides. Also described are screening methods for identifying inhibitors and/or activators, as well as methods for antibody production.
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公开(公告)号:US06936693B2
公开(公告)日:2005-08-30
申请号:US10771708
申请日:2004-02-04
申请人: Michelle Coutu Hresko , Merry B. McLaird , Deryck J. Williams , Anita M. Frevert , Brandi Chiapelli , Catherine Baublite , Andrew P. Kloek , Jennifer A. Davila-Aponte , John D. Bradley , Siqun Xu
发明人: Michelle Coutu Hresko , Merry B. McLaird , Deryck J. Williams , Anita M. Frevert , Brandi Chiapelli , Catherine Baublite , Andrew P. Kloek , Jennifer A. Davila-Aponte , John D. Bradley , Siqun Xu
IPC分类号: A61K38/17 , C07H21/04 , C07K1/00 , C07K14/00 , C07K14/435 , C07K14/705 , C07K17/00 , C12N20060101 , C12N15/00 , C12P21/06 , C12Q1/68
CPC分类号: C07K14/705
摘要: Nucleic acid molecules from nematodes encoding PAN and ZP domain containing receptor polypeptides are described. PANZP polypeptide sequences are also provided, as are vectors, host cells, and recombinant methods for production of PANZP nucleotides and polypeptides. Also described are screening methods for identifying inhibitors and/or activators, as well as methods for antibody production.
摘要翻译: 描述了编码含有PAN和ZP结构域的受体多肽的线虫的核酸分子。 还提供PANZP多肽序列,载体,宿主细胞以及用于产生PANZP核苷酸和多肽的重组方法。 还描述了用于鉴定抑制剂和/或激活剂的筛选方法以及用于抗体生产的方法。
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公开(公告)号:US20080249160A1
公开(公告)日:2008-10-09
申请号:US12105591
申请日:2008-04-18
申请人: Deryck J. Williams , Andrew P. Kloek , Michelle Coutu Hresko , Barry J. Shortt , Jennifer A. Davila-Aponte , John D. Bradley , James McCarter , Merry B. McLaird
发明人: Deryck J. Williams , Andrew P. Kloek , Michelle Coutu Hresko , Barry J. Shortt , Jennifer A. Davila-Aponte , John D. Bradley , James McCarter , Merry B. McLaird
摘要: Certain fatty acids and related compounds useful in the control nematodes that infest plants or the situs of plants are described. Nematodes that parasitize animals can also be controlled using the methods and compounds of this invention.
摘要翻译: 描述了可用于控制线虫的某些脂肪酸和相关化合物,其侵染植物或植物的部位。 也可以使用本发明的方法和化合物来控制寄生动物的线虫。
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公开(公告)号:US20090318563A1
公开(公告)日:2009-12-24
申请号:US12342720
申请日:2008-12-23
申请人: Michelle Coutu Hresko , Deryck J. Williams , Merry B. McLaird , John D. Bradley , Barry J. Shortt , Ronald E. Worthington
发明人: Michelle Coutu Hresko , Deryck J. Williams , Merry B. McLaird , John D. Bradley , Barry J. Shortt , Ronald E. Worthington
IPC分类号: A01N33/08 , C07C215/06 , C07C215/20 , A01P5/00
CPC分类号: A01N33/04 , A01N33/06 , A01N33/08 , A01N33/10 , A01N33/12 , A01N33/26 , A01N37/32 , A01N41/08 , A01N41/10 , A01N43/50 , A01N43/647 , A01N57/12 , A01N57/20
摘要: Certain ethanolamine analogs and related compounds useful in the control of nematodes that infest plants or the situs of plants are described. Nematodes that parasitize animals can also be controlled using the methods and compounds of this invention
摘要翻译: 描述了可用于控制侵染植物或植物部位的线虫的某些乙醇胺类似物和相关化合物。 也可以使用本发明的方法和化合物来控制寄生动物的线虫
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公开(公告)号:US20110107446A1
公开(公告)日:2011-05-05
申请号:US12865845
申请日:2009-02-09
申请人: John D. Bradley , Catherine C. Baublite , Michael J. Crawford , Stanislaw Flasinski , Deryck J. Williams
发明人: John D. Bradley , Catherine C. Baublite , Michael J. Crawford , Stanislaw Flasinski , Deryck J. Williams
IPC分类号: A01H1/02 , C07H21/00 , C07H21/04 , C12N15/82 , C12N5/10 , A01H5/00 , A01H5/02 , A01H5/12 , A01H5/10 , A01H5/06 , A01H1/06 , A23L1/36 , A23L1/28
CPC分类号: C12N15/8285 , A01H1/02 , C12N15/8286 , Y02A40/162 , Y02A40/164
摘要: The present invention is directed to controlling nematode infestation. The invention discloses methods and compositions for use in controlling nematode infestation by providing recombinant DNA molecules to the cells of a plant in order to achieve a reduction in nematode infestation. The invention is also directed to methods for making transgenic plants that express the recombinant DNA molecule for use in protecting plants from nematode infestation.
摘要翻译: 本发明涉及控制线虫侵染。 本发明公开了通过向植物细胞提供重组DNA分子来控制线虫侵袭的方法和组合物,以实现线虫侵染的减少。 本发明还涉及用于制备表达用于保护植物免于线虫侵袭的重组DNA分子的转基因植物的方法。
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公开(公告)号:US06818433B1
公开(公告)日:2004-11-16
申请号:US10082894
申请日:2002-02-26
IPC分类号: C12N912
CPC分类号: C12Y504/02001 , C07H21/04 , C12N9/90
摘要: Disclosed is a nucleic acid molecule from nematodes encoding for phosphoglycerate mutase (PGM) polypeptides. The PGM-like polypeptide sequence is also provided, as are vectors, host cells, and recombinant methods for production of PGM-like nucleotides and polypeptides. The invention further relates to screening methods for identifying inhibitors and/or activators, as well as methods for antibody production. Such inhibitors are useful for control nematode infection.
摘要翻译: 公开了编码磷酸甘油酸变位酶(PGM)多肽的线虫的核酸分子。 还提供PGM样多肽序列,载体,宿主细胞以及用于产生PGM样核苷酸和多肽的重组方法。 本发明还涉及用于鉴定抑制剂和/或激活剂的筛选方法以及用于抗体生产的方法。 这种抑制剂可用于控制线虫感染。
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