Nematode PGM-like sequences
    20.
    发明授权
    Nematode PGM-like sequences 有权
    线虫PGM样序列

    公开(公告)号:US06818433B1

    公开(公告)日:2004-11-16

    申请号:US10082894

    申请日:2002-02-26

    IPC分类号: C12N912

    摘要: Disclosed is a nucleic acid molecule from nematodes encoding for phosphoglycerate mutase (PGM) polypeptides. The PGM-like polypeptide sequence is also provided, as are vectors, host cells, and recombinant methods for production of PGM-like nucleotides and polypeptides. The invention further relates to screening methods for identifying inhibitors and/or activators, as well as methods for antibody production. Such inhibitors are useful for control nematode infection.

    摘要翻译: 公开了编码磷酸甘油酸变位酶(PGM)多肽的线虫的核酸分子。 还提供PGM样多肽序列,载体,宿主细胞以及用于产生PGM样核苷酸和多肽的重组方法。 本发明还涉及用于鉴定抑制剂和/或激活剂的筛选方法以及用于抗体生产的方法。 这种抑制剂可用于控制线虫感染。