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11.发明申请Postpartum cells derived from umbilical cord tissue, and methods of making and using the same 有权来自脐带组织的产后细胞，以及制造和使用它们的方法公开(公告)号：US20050054098A1
公开(公告)日：2005-03-10
申请号：US10877012
申请日：2004-06-25
申请人： Sanjay Mistry , Anthony Kihm , Ian Harris , Alexander Harmon , Darin Messina , Agnieszka Seyda , Chin-Feng Yi , Anna Gosiewska
发明人： Sanjay Mistry , Anthony Kihm , Ian Harris , Alexander Harmon , Darin Messina , Agnieszka Seyda , Chin-Feng Yi , Anna Gosiewska
CPC分类号： A61K35/51 , A01N1/0226 , A61K35/12 , A61K35/50 , A61K38/18 , A61K38/1808 , A61K38/1825 , A61K38/1833 , A61K38/1841 , A61K38/185 , A61K38/1858 , A61K38/1866 , A61K38/1891 , A61K38/19 , A61K38/204 , A61K38/2053 , A61K38/27 , A61K45/06 , C12N5/0605 , C12N5/0606 , C12N5/0607 , C12N2500/32 , C12N2500/34 , C12N2500/44 , C12N2500/90 , C12N2500/95 , C12N2501/12 , C12N2501/21 , C12N2501/23 , C12N2502/02 , C12N2506/02 , C12N2506/03 , C12N2509/00 , C12N2509/10 , C12N2533/50
摘要： Cells derived from human umbilical cords are disclosed along with methods for their therapeutic use. Isolation techniques, culture methods and detailed characterization of the cells with respect to their cell surface markers, gene expression, and their secretion of trophic factors are described.
摘要翻译： 公开了源自人脐带的细胞及其治疗用途的方法。 描述了相对于其细胞表面标志物的细胞的分离技术，培养方法和详细表征，基因表达及其营养因子的分泌。
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12.发明申请公开(公告)号：US20050037491A1
公开(公告)日：2005-02-17
申请号：US10877541
申请日：2004-06-25
申请人： Sanjay Mistry , Darin Messina , Ian Harris , Alexander Harmon , Anthony Kihm , Agnieszka Seyda , Chin-Feng Yi , Anna Gosiewska
发明人： Sanjay Mistry , Darin Messina , Ian Harris , Alexander Harmon , Anthony Kihm , Agnieszka Seyda , Chin-Feng Yi , Anna Gosiewska
CPC分类号： A61K35/51 , A01N1/0226 , A61K35/12 , A61K35/50 , A61K38/18 , A61K38/1808 , A61K38/1825 , A61K38/1833 , A61K38/1841 , A61K38/185 , A61K38/1858 , A61K38/1866 , A61K38/1891 , A61K38/19 , A61K38/204 , A61K38/2053 , A61K38/27 , A61K45/06 , C12N5/0605 , C12N5/0606 , C12N5/0607 , C12N2500/32 , C12N2500/34 , C12N2500/44 , C12N2500/90 , C12N2500/95 , C12N2501/12 , C12N2501/21 , C12N2501/23 , C12N2502/02 , C12N2506/02 , C12N2506/03 , C12N2509/00 , C12N2509/10 , C12N2533/50
摘要： Cells derived from postpartum umbilicus and placenta are disclosed. Pharmaceutical compositions, devices and methods for the regeneration or repair of ocular tissue using the postpartum-derived cells are also disclosed.
摘要翻译： 公开了产自产后脐带和胎盘的细胞。 还公开了使用产后来源细胞再生或修复眼组织的药物组合物，装置和方法。
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13.发明申请公开(公告)号：US20070036767A1
公开(公告)日：2007-02-15
申请号：US11481456
申请日：2006-07-06
申请人： Sanjay Mistry , Anthony Kihm , Ian Harris , Alexander Harmon , Darin Messina , Agnieszka Seyda , Anna Gosiewska
发明人： Sanjay Mistry , Anthony Kihm , Ian Harris , Alexander Harmon , Darin Messina , Agnieszka Seyda , Anna Gosiewska
CPC分类号： A61K35/51 , A01N1/0226 , A61K35/12 , A61K35/50 , A61K38/18 , A61K38/1808 , A61K38/1825 , A61K38/1833 , A61K38/1841 , A61K38/185 , A61K38/1858 , A61K38/1866 , A61K38/1891 , A61K38/19 , A61K38/204 , A61K38/2053 , A61K38/27 , A61K45/06 , C12N5/0605 , C12N5/0606 , C12N5/0607 , C12N2500/32 , C12N2500/34 , C12N2500/44 , C12N2500/90 , C12N2500/95 , C12N2501/12 , C12N2501/21 , C12N2501/23 , C12N2502/02 , C12N2506/02 , C12N2506/03 , C12N2509/00 , C12N2509/10 , C12N2533/50
摘要： Cells derived from human umbilical cords are disclosed along with methods for their therapeutic use. Isolation techniques, culture methods and detailed characterization of the cells with respect to their cell surface markers, gene expression, and their secretion of trophic factors are described.
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公开(公告)号：US20060154367A1
公开(公告)日：2006-07-13
申请号：US11322003
申请日：2005-12-29
申请人： Anthony Kihm , Agnieszka Seyda , Sridevi Dhanaraj , Ziwei Wang , Alexander Harmon , Ian Harris , Darin Messina , Sanjay Mistry , Anna Gosiewska
发明人： Anthony Kihm , Agnieszka Seyda , Sridevi Dhanaraj , Ziwei Wang , Alexander Harmon , Ian Harris , Darin Messina , Sanjay Mistry , Anna Gosiewska
CPC分类号： A61K35/51 , A01N1/0226 , A61K35/12 , A61K35/50 , A61K38/18 , A61K38/1808 , A61K38/1825 , A61K38/1833 , A61K38/1841 , A61K38/185 , A61K38/1858 , A61K38/1866 , A61K38/1891 , A61K38/19 , A61K38/204 , A61K38/2053 , A61K38/27 , A61K45/06 , C12N5/0605 , C12N5/0606 , C12N5/0607 , C12N2500/32 , C12N2500/34 , C12N2500/44 , C12N2500/90 , C12N2500/95 , C12N2501/12 , C12N2501/21 , C12N2501/23 , C12N2502/02 , C12N2506/02 , C12N2506/03 , C12N2509/00 , C12N2509/10 , C12N2533/50
摘要： Cells derived from postpartum tissue and methods for their isolation and induction to differentiate to cells of a chondrogenic or osteogenic phenotype are provided by the invention. The invention further provides cultures and compositions of the postpartum-derived cells and products related thereto. The postpartum-derived cells of the invention and products related thereto have a plethora of uses, including but not limited to research, diagnostic, and therapeutic applications, for example, in the treatment of bone and cartilage conditions.
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15.发明申请Postpartum cells derived from umbilical cord tissue, and methods of making and using the same 审中-公开来自脐带组织的产后细胞，以及制造和使用它们的方法公开(公告)号：US20060223177A1
公开(公告)日：2006-10-05
申请号：US11315897
申请日：2005-12-22
申请人： Ian Harris , Darin Messina , Anthony Kihm , Agnieszka Seyda , David Colter
发明人： Ian Harris , Darin Messina , Anthony Kihm , Agnieszka Seyda , David Colter
CPC分类号： C12N5/0607 , C12N5/0619 , C12N2500/32 , C12N2500/90 , C12N2501/11 , C12N2501/115 , C12N2501/119 , C12N2501/135 , C12N2506/03
摘要： Cells derived from human umbilical cords are disclosed along with methods for their therapeutic use. Isolation techniques, culture methods and detailed characterization of the cells with respect to their cell surface markers, gene expression, and their secretion of trophic factors are described.
摘要翻译： 公开了源自人脐带的细胞及其治疗用途的方法。 描述了相对于其细胞表面标志物的细胞的分离技术，培养方法和详细表征，基因表达及其营养因子的分泌。
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16.发明申请公开(公告)号：US20070160588A1
公开(公告)日：2007-07-12
申请号：US11617346
申请日：2006-12-28
申请人： Anthony Kihm
发明人： Anthony Kihm
CPC分类号： C12N5/0605 , A61K35/48 , A61K35/50 , A61L27/3804 , A61L27/3839 , A61L27/3886 , A61L27/3895 , C12N2510/00
摘要： Compositions and methods of using cells derived from postpartum tissue such as the umbilical cord and placenta, to stimulate and support angiogenesis, to improve blood flow, to regenerate, repair, and improve skeletal muscle damaged by a peripheral ischemic event, and to protect skeletal muscle from ischemic damage in peripheral vascular disease patients are disclosed.
摘要翻译： 使用衍生自产后组织（例如脐带和胎盘）的细胞刺激和支持血管生成，改善血液流动，再生，修复和改善由外周缺血事件损伤的骨骼肌并且保护骨骼肌的组合物和方法 来自外周血管疾病患者的缺血性损伤。
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