公开(公告)号：US20160367173A1

公开(公告)日：2016-12-22

申请号：US15160907

申请日：2016-05-20

Applicant: Cercacor Laboratories, Inc.

Inventor： Cristiano Dalvi ,  Ferdyan Lesmana ,  Hung Vo ,  Jeroen Poeze ,  Jesse Chen ,  Kevin Pauley ,  Mathew Paul ,  Sean Merritt ,  Thomas B. Blank ,  Massi Joe E. Kiani

IPC: A61B5/145 ,  A61B5/1455 ,  A61B5/00

CPC classification number: A61B5/14552 ,  A61B5/0075 ,  A61B5/6838 ,  A61B2562/0238

Abstract: An optical physiological sensor configured to perform high speed spectral sweep analysis of sample tissue being measured to non-invasively predict an analyte level of a patient. An emitter of the optical physiological sensor can be regulated to operate at different temperatures to emit radiation at different wavelengths. Variation in emitter drive current, duty cycle, and forward voltage can also be used to cause the emitter to emit a range of wavelengths. Informative spectral data can be obtained during the sweeping of specific wavelength regions of sample tissue.

Abstract translation: 一种光学生理传感器，其被配置为对被测量的样品组织进行高速光谱扫描分析，以非侵入性地预测患者的分析物水平。 可以调节光学生理传感器的发射器以在不同温度下操作以发射不同波长的辐射。 发射极驱动电流，占空比和正向电压的变化也可用于使发射极发射波长范围。 在扫描样品组织的特定波长区域期间可以获得信息谱数据。

公开(公告)号：US08909310B2

公开(公告)日：2014-12-09

申请号：US14153895

申请日：2014-01-13

Applicant: Cercacor Laboratories, Inc.

Inventor： Marcelo M. Lamego ,  Sean Merritt ,  Cristiano Dalvi ,  Hung Vo ,  Johannes Bruinsma ,  Jeroen Poeze ,  Ferdyan Lesmana ,  Massi Joe E. Kiani

IPC: A61B5/00 ,  A61B5/145 ,  A61B5/1455

CPC classification number: A61B5/1455 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/14552 ,  A61B5/6816 ,  A61B5/6826 ,  A61B5/6829 ,  A61B5/6838 ,  A61B5/6843 ,  A61B2562/0233 ,  A61B2562/04 ,  A61B2562/046 ,  A61B2562/146

Abstract: The present disclosure relates to an interface for a noninvasive glucose sensor that comprises a front-end adapted to receive an input signals from optical detectors and provide corresponding digital signals. In one embodiment, the front-end comprises switched capacitor circuits that are capable of handling multiple streams signals from the optical detectors. In another embodiment, the front-end comprises transimpedance amplifiers that are capable of handling multiple streams of input signals. In this embodiment, the transimpedance amplifier may be configured based on its own characteristics, such as its impedance, the impedance of the photodiodes to which it is coupled, and the number of photodiodes to which it is coupled.

公开(公告)号：US20140121482A1

公开(公告)日：2014-05-01

申请号：US14064055

申请日：2013-10-25

Applicant: CERCACOR LABORATORIES, INC.

Inventor： Sean Merritt ,  Marcelo Lamego ,  Cristiano Dalvi ,  Hung Vo ,  Johannes Bruinsma ,  Jeroen Poeze ,  Ferdyan Lesmana ,  Massi Joe E. Kiani

IPC: A61B5/1455

CPC classification number: A61B5/1455 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/14552 ,  A61B5/6816 ,  A61B5/6826 ,  A61B5/6829 ,  A61B5/6838 ,  A61B5/6843 ,  A61B2562/0233 ,  A61B2562/04 ,  A61B2562/046 ,  A61B2562/146

Abstract: The present disclosure relates to a sensor having a set of photodetectors that are arranged at various locations to enable the measurement of blood glucose. The photodetectors are arranged across multiple locations. For example, the detector may comprise multiple photodetector arrays that are arranged to have a sufficient difference in mean path length to allow for noise cancellation and noise reduction. Walls may be used in the detector to separate individual photodetectors and prevent mixing of detected optical radiation between the different locations on the measurement site. A window may also be employed to facilitate the passing of optical radiation at various wavelengths for measuring glucose in the tissue.

Abstract translation: 本公开涉及具有一组光电检测器的传感器，其被布置在各种位置以能够测量血糖。 光电探测器布置在多个位置。 例如，检测器可以包括多个光电检测器阵列，其布置成在平均路径长度上具有足够的差异以允许噪声消除和降噪。 可以在检测器中使用壁来分离各个光电检测器，并防止检测的光辐射在测量位置上的不同位置之间的混合。 还可以使用窗口来促进用于测量组织中葡萄糖的各种波长的光辐射的通过。

公开(公告)号：US20130317370A1

公开(公告)日：2013-11-28

申请号：US13888266

申请日：2013-05-06

Applicant: Cercacor Laboratories, Inc.

Inventor： Cristiano Dalvi ,  Marcelo Lamego ,  Sean Merritt ,  Hung Vo ,  Johannes Bruinsma ,  Jeroen Poeze ,  Ferydan Lesmana ,  Greg Olsen ,  Massi Joe E. Kiani

IPC: A61B5/024 ,  A61B5/145 ,  A61B5/00 ,  A61B5/1455

CPC classification number: A61B5/02427 ,  A61B5/02416 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/14551 ,  A61B5/14552 ,  A61B5/4875 ,  A61B5/6816 ,  A61B5/6826 ,  A61B5/6829 ,  A61B5/6838 ,  A61B5/6843 ,  A61B5/70 ,  A61B5/7275 ,  A61B2562/146

Abstract: A noninvasive physiological sensor for measuring one or more physiological parameters of a medical patient can include a bump interposed between a light source and a photodetector. The bump can be placed in contact with body tissue of a patient and thereby reduce a thickness of the body tissue. As a result, an optical pathlength between the light source and the photodetector can be reduced. In addition, the sensor can include a heat sink that can direct heat away from the light source. Moreover, the sensor can include shielding in the optical path between the light source and the photodetector. The shielding can reduce noise received by the photodetector.

Abstract translation: 用于测量医疗患者的一个或多个生理参数的无创生理传感器可以包括插入在光源和光电检测器之间的凸块。 凸起可以放置成与患者的身体组织接触，从而减少身体组织的厚度。 结果，可以减少光源和光电检测器之间的光程。 此外，传感器可以包括可将热量远离光源引导的散热器。 此外，传感器可以包括在光源和光电检测器之间的光路中的屏蔽。 屏蔽可以降低由光电检测器接收的噪声。

公开(公告)号：US20240164668A1

公开(公告)日：2024-05-23

申请号：US18520380

申请日：2023-11-27

Applicant: Cercacor Laboratories, Inc.

Inventor： Kevin Pauley ,  Cristiano Dalvi ,  Hung Vo ,  Jesse Chen ,  Ferdyan Lesmana ,  Jeroen Poeze ,  Sean Merritt

IPC: A61B5/1455 ,  A61B5/00 ,  A61B5/145 ,  G01J1/16 ,  G01N21/31 ,  G01N21/47 ,  G01N21/49 ,  G01N21/59

CPC classification number: A61B5/14552 ,  A61B5/14532 ,  A61B5/14535 ,  A61B5/14539 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/4875 ,  G01J1/1626 ,  G01N21/31 ,  G01N21/4738 ,  G01N21/49 ,  G01N21/59 ,  A61B2562/0238 ,  G01J2001/1636 ,  G01J2001/1652 ,  G01N2021/3181

Abstract: An optical measurement device includes a light source, a first detector, and a second detector. The light source emits light to a measurement site of a patient and one or more detectors detect the light from the light source. At least a portion of a detector is translucent and the light passes through the translucent portion prior to reaching the measurement site. A detector receives the light after attenuation and/or reflection or refraction by the measurement site. A processor determines a light intensity of the light source, a light intensity through a tissue site, or a light intensity of reflected or refracted light based on light detected by the one or more detectors. The processor can estimate a concentration of an analyte at the measurement site or an absorption or reflection at the measurement site.

公开(公告)号：US11864890B2

公开(公告)日：2024-01-09

申请号：US16985497

申请日：2020-08-05

Applicant: Cercacor Laboratories, Inc.

Inventor： Kevin Pauley ,  Cristiano Dalvi ,  Hung Vo ,  Jesse Chen ,  Ferdyan Lesmana ,  Jeroen Poeze ,  Sean Merritt

IPC: A61B5/1455 ,  A61B5/145 ,  G01J1/16 ,  G01N21/47 ,  G01N21/31 ,  G01N21/49 ,  A61B5/00 ,  G01N21/59

CPC classification number: A61B5/14552 ,  A61B5/14532 ,  A61B5/14535 ,  A61B5/14539 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/4875 ,  G01J1/1626 ,  G01N21/31 ,  G01N21/4738 ,  G01N21/49 ,  G01N21/59 ,  A61B2562/0238 ,  G01J2001/1636 ,  G01J2001/1652 ,  G01N2021/3181

Abstract: An optical measurement device includes a light source, a first detector, and a second detector. The light source emits light to a measurement site of a patient and one or more detectors detect the light from the light source. At least a portion of a detector is translucent and the light passes through the translucent portion prior to reaching the measurement site. A detector receives the light after attenuation and/or reflection or refraction by the measurement site. A processor determines a light intensity of the light source, a light intensity through a tissue site, or a light intensity of reflected or refracted light based on light detected by the one or more detectors. The processor can estimate a concentration of an analyte at the measurement site or an absorption or reflection at the measurement site.

公开(公告)号：US10750984B2

公开(公告)日：2020-08-25

申请号：US15850755

申请日：2017-12-21

Applicant: Cercacor Laboratories, Inc.

Inventor： Kevin Pauley ,  Cristiano Dalvi ,  Hung Vo ,  Jesse Chen ,  Ferdyan Lesmana ,  Jeroen Poeze ,  Sean Merritt

IPC: A61B5/1455 ,  A61B5/145 ,  G01J1/16 ,  G01N21/47 ,  G01N21/31 ,  G01N21/49 ,  A61B5/00 ,  G01N21/59

Abstract: An optical measurement device includes a light source, a first detector, and a second detector. The light source emits light to a measurement site of a patient and one or more detectors detect the light from the light source. At least a portion of a detector is translucent and the light passes through the translucent portion prior to reaching the measurement site. A detector receives the light after attenuation and/or reflection or refraction by the measurement site. A processor determines a light intensity of the light source, a light intensity through a tissue site, or a light intensity of reflected or refracted light based on light detected by the one or more detectors. The processor can estimate a concentration of an analyte at the measurement site or an absorption or reflection at the measurement site.

公开(公告)号：US20190142283A1

公开(公告)日：2019-05-16

申请号：US16230734

申请日：2018-12-21

Applicant: Cercacor Laboratories, Inc.

Inventor： Marcelo M. Lamego ,  Massi Joe E. Kiani ,  Jeroen Poeze ,  Cristiano Dalvi ,  Sean Merritt ,  Hung Vo ,  Gregory A. Olsen ,  Ferdyan Lesmana

IPC: A61B5/0205 ,  A61B5/00 ,  A61B5/1455 ,  A61B5/145 ,  A61B5/1459

CPC classification number: A61B5/0205 ,  A61B5/0022 ,  A61B5/021 ,  A61B5/0816 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/1459 ,  A61B5/7435 ,  A61B5/7475 ,  A61B2560/0223 ,  A61B2560/0431

Abstract: The present disclosure includes a handheld processing device including medical applications for minimally and noninvasive glucose measurements. In an embodiment, the device creates a patient specific calibration using a measurement protocol of minimally invasive measurements and noninvasive measurements, eventually creating a patient specific noninvasive glucometer. Additionally, embodiments of the present disclosure provide for the processing device to execute medical applications and non-medical applications.

公开(公告)号：US10159412B2

公开(公告)日：2018-12-25

申请号：US14703816

申请日：2015-05-04

Applicant: Cercacor Laboratories, Inc.

Inventor： Marcelo M. Lamego ,  Massi Joe E. Kiani ,  Jeroen Poeze ,  Cristiano Dalvi ,  Sean Merritt ,  Hung Vo ,  Gregory A. Olsen ,  Ferdyan Lesmana

IPC: A61B5/1455 ,  A61B5/0205 ,  A61B5/145 ,  A61B5/00 ,  A61B5/1459 ,  A61B5/021 ,  A61B5/08

Abstract: The present disclosure includes a handheld processing device including medical applications for minimally and noninvasive glucose measurements. In an embodiment, the device creates a patient specific calibration using a measurement protocol of minimally invasive measurements and noninvasive measurements, eventually creating a patient specific noninvasive glucometer. Additionally, embodiments of the present disclosure provide for the processing device to execute medical applications and non-medical applications.

公开(公告)号：US20180199871A1

公开(公告)日：2018-07-19

申请号：US15850755

申请日：2017-12-21

Applicant: Cercacor Laboratories, Inc.

Inventor： Kevin Pauley ,  Cristiano Dalvi ,  Hung Vo ,  Jesse Chen ,  Ferdyan Lesmana ,  Jeroen Poeze ,  Sean Merritt

IPC: A61B5/1455 ,  A61B5/145 ,  A61B5/00 ,  G01N21/59

CPC classification number: A61B5/14552 ,  A61B5/14532 ,  A61B5/14535 ,  A61B5/14539 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/4875 ,  A61B2562/0238 ,  G01J1/1626 ,  G01J2001/1636 ,  G01J2001/1652 ,  G01N21/31 ,  G01N21/4738 ,  G01N21/49 ,  G01N21/59 ,  G01N2021/3181

Abstract: An optical measurement device includes a light source, a first detector, and a second detector. The light source emits light to a measurement site of a patient and one or more detectors detect the light from the light source. At least a portion of a detector is translucent and the light passes through the translucent portion prior to reaching the measurement site. A detector receives the light after attenuation and/or reflection or refraction by the measurement site. A processor determines a light intensity of the light source, a light intensity through a tissue site, or a light intensity of reflected or refracted light based on light detected by the one or more detectors. The processor can estimate a concentration of an analyte at the measurement site or an absorption or reflection at the measurement site.