公开(公告)号：US20240164668A1

公开(公告)日：2024-05-23

申请号：US18520380

申请日：2023-11-27

Applicant: Cercacor Laboratories, Inc.

Inventor： Kevin Pauley ,  Cristiano Dalvi ,  Hung Vo ,  Jesse Chen ,  Ferdyan Lesmana ,  Jeroen Poeze ,  Sean Merritt

IPC: A61B5/1455 ,  A61B5/00 ,  A61B5/145 ,  G01J1/16 ,  G01N21/31 ,  G01N21/47 ,  G01N21/49 ,  G01N21/59

CPC classification number: A61B5/14552 ,  A61B5/14532 ,  A61B5/14535 ,  A61B5/14539 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/4875 ,  G01J1/1626 ,  G01N21/31 ,  G01N21/4738 ,  G01N21/49 ,  G01N21/59 ,  A61B2562/0238 ,  G01J2001/1636 ,  G01J2001/1652 ,  G01N2021/3181

Abstract: An optical measurement device includes a light source, a first detector, and a second detector. The light source emits light to a measurement site of a patient and one or more detectors detect the light from the light source. At least a portion of a detector is translucent and the light passes through the translucent portion prior to reaching the measurement site. A detector receives the light after attenuation and/or reflection or refraction by the measurement site. A processor determines a light intensity of the light source, a light intensity through a tissue site, or a light intensity of reflected or refracted light based on light detected by the one or more detectors. The processor can estimate a concentration of an analyte at the measurement site or an absorption or reflection at the measurement site.

公开(公告)号：US11864890B2

公开(公告)日：2024-01-09

申请号：US16985497

申请日：2020-08-05

Applicant: Cercacor Laboratories, Inc.

Inventor： Kevin Pauley ,  Cristiano Dalvi ,  Hung Vo ,  Jesse Chen ,  Ferdyan Lesmana ,  Jeroen Poeze ,  Sean Merritt

IPC: A61B5/1455 ,  A61B5/145 ,  G01J1/16 ,  G01N21/47 ,  G01N21/31 ,  G01N21/49 ,  A61B5/00 ,  G01N21/59

CPC classification number: A61B5/14552 ,  A61B5/14532 ,  A61B5/14535 ,  A61B5/14539 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/4875 ,  G01J1/1626 ,  G01N21/31 ,  G01N21/4738 ,  G01N21/49 ,  G01N21/59 ,  A61B2562/0238 ,  G01J2001/1636 ,  G01J2001/1652 ,  G01N2021/3181

Abstract: An optical measurement device includes a light source, a first detector, and a second detector. The light source emits light to a measurement site of a patient and one or more detectors detect the light from the light source. At least a portion of a detector is translucent and the light passes through the translucent portion prior to reaching the measurement site. A detector receives the light after attenuation and/or reflection or refraction by the measurement site. A processor determines a light intensity of the light source, a light intensity through a tissue site, or a light intensity of reflected or refracted light based on light detected by the one or more detectors. The processor can estimate a concentration of an analyte at the measurement site or an absorption or reflection at the measurement site.

公开(公告)号：US20180199871A1

公开(公告)日：2018-07-19

申请号：US15850755

申请日：2017-12-21

Applicant: Cercacor Laboratories, Inc.

Inventor： Kevin Pauley ,  Cristiano Dalvi ,  Hung Vo ,  Jesse Chen ,  Ferdyan Lesmana ,  Jeroen Poeze ,  Sean Merritt

IPC: A61B5/1455 ,  A61B5/145 ,  A61B5/00 ,  G01N21/59

CPC classification number: A61B5/14552 ,  A61B5/14532 ,  A61B5/14535 ,  A61B5/14539 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/4875 ,  A61B2562/0238 ,  G01J1/1626 ,  G01J2001/1636 ,  G01J2001/1652 ,  G01N21/31 ,  G01N21/4738 ,  G01N21/49 ,  G01N21/59 ,  G01N2021/3181

Abstract: An optical measurement device includes a light source, a first detector, and a second detector. The light source emits light to a measurement site of a patient and one or more detectors detect the light from the light source. At least a portion of a detector is translucent and the light passes through the translucent portion prior to reaching the measurement site. A detector receives the light after attenuation and/or reflection or refraction by the measurement site. A processor determines a light intensity of the light source, a light intensity through a tissue site, or a light intensity of reflected or refracted light based on light detected by the one or more detectors. The processor can estimate a concentration of an analyte at the measurement site or an absorption or reflection at the measurement site.

公开(公告)号：US08207676B2

公开(公告)日：2012-06-26

申请号：US12676629

申请日：2008-09-08

Applicant: Achim Hilgers

Inventor： Achim Hilgers

IPC: H05B37/02 ,  H05B41/24

CPC classification number: G01J1/04 ,  G01J1/02 ,  G01J1/0214 ,  G01J1/0407 ,  G01J1/0474 ,  G01J1/4204 ,  G01J1/4228 ,  G01J3/02 ,  G01J3/0205 ,  G01J3/021 ,  G01J3/0256 ,  G01J3/0262 ,  G01J3/0291 ,  G01J3/50 ,  G01J3/505 ,  G01J2001/1636 ,  H05B33/0803 ,  H05B33/0869 ,  H05B33/0872

Abstract: The present invention relates to a solid-state based light source, a corresponding circuitry and a method of emitting light, including one or more light source elements for generating light, a first sensor for receiving light emitted by the light source elements and ambient light and for generating a first sensor signal (S1) representing the received light, a second sensor for only receiving ambient light and for generating a second sensor signal (S2) representing the received ambient light. Moreover, the solid-state based light source comprises a control unit for receiving the first and the second sensor signals (S1, S2) and for generating control signals (Sc) for controlling the light source elements, based on the difference between the first and the second sensor signals (S1, S2), to compensate for the influence of the ambient light.

Abstract translation: 本发明涉及一种基于固态的光源，包括用于产生光的一个或多个光源元件的发光的对应电路和方法，用于接收由光源元件发出的光和环境光的第一传感器， 用于产生表示所接收的光的第一传感器信号（S1），用于仅接收环境光并用于产生表示所接收的环境光的第二传感器信号（S2）的第二传感器。 此外，基于固态的光源包括控制单元，用于接收第一和第二传感器信号（S1，S2），并且用于产生用于控制光源元件的控制信号（Sc），基于第一和第二传感器信号 第二传感器信号（S1，S2），以补偿环境光的影响。

公开(公告)号：US5260584A

公开(公告)日：1993-11-09

申请号：US911501

申请日：1992-07-10

Applicant: Stephen J. Popson ,  Kenneth A. Richey

Inventor： Stephen J. Popson ,  Kenneth A. Richey

IPC: G01J1/16 ,  G01N21/47 ,  G01N21/86

CPC classification number: G01N21/474 ,  G01J2001/1636 ,  G01N2021/4766 ,  G01N2021/8663 ,  G01N2201/06153 ,  G01N2201/0621

Abstract: A portable, hand held reflectometer which employs at least one blue light emitting diode for measuring the optical brightness of an opaque material, such as a stack or pad of paper is disclosed. A brightness measuring reflectometer which employs two blue light emitting diodes arranged so as to substantially reduce measured brightness variations caused by changing the orientation of the reflectometer relative to that of the fibers contained in a fibrous material such as paper whose brightness is to be measured is also disclosed. An ultraviolet light source such as a fluorescent lamp is also employed for measuring the brightness of paper or other materials which contain ultraviolet light excitable blue wavelength emitting substances. An electronic circuit for operating the reflectometer is also disclosed which employs a negative feedback circuit for maintaining the intensity of the ultraviolet light source at a relatively constant level.

Abstract translation: 公开了一种便携式手持式反射计，其采用至少一个蓝色发光二极管来测量不透明材料（诸如纸堆或纸）的光学亮度。 使用两个蓝色发光二极管的亮度测量反射计，该蓝色发光二极管被布置成基本上减少由反射计相对于包含在诸如要测量其亮度的纸的纤维材料中的纤维的取向而引起的测量的亮度变化 披露 诸如荧光灯的紫外光源也用于测量含有紫外线可激发蓝色波长发射物质的纸张或其他材料的亮度。 还公开了一种用于操作反射计的电子电路，其采用负反馈电路以将紫外光源的强度保持在相对恒定的水平。

公开(公告)号：US4998043A

公开(公告)日：1991-03-05

申请号：US345883

申请日：1989-05-01

Applicant: Yoshihara Unami ,  Masao Tanaka

Inventor： Yoshihara Unami ,  Masao Tanaka

IPC: G01J1/16 ,  G01N21/25 ,  G01S7/491 ,  H05B33/08

CPC classification number: H05B33/0851 ,  G01N21/255 ,  H05B33/0803 ,  G01J2001/1636 ,  G01N2201/0621 ,  G01N2201/069 ,  G01S7/4911

Abstract: An LED stabilizing light source device comprises an LED, a drive circuit for driving the LED, a wavelength filter for filtering the light emitted from the LED, a light splitter for splitting the light passing through the filter, a photodiode for receiving the split light. The device further comprises a feedback loop for feeding an output of the photodiode to the drive circuit.

Abstract translation: LED稳定光源装置包括LED，用于驱动LED的驱动电路，用于对从LED发射的光进行滤波的波长滤波器，用于分离通过滤光器的光的分光器，用于接收分离光的光电二极管。 该装置还包括用于将光电二极管的输出馈送到驱动电路的反馈回路。

公开(公告)号：US5691817A

公开(公告)日：1997-11-25

申请号：US700155

申请日：1996-08-20

Applicant: Mark A. Cargill ,  Bernard J. Berg

Inventor： Mark A. Cargill ,  Bernard J. Berg

IPC: G01J1/02 ,  G01J1/16 ,  G01J1/42 ,  G01J3/02 ,  G01J3/28 ,  G01J3/51 ,  G01N21/27 ,  G01N21/47 ,  G01N21/25

CPC classification number: G01N21/474 ,  G01J3/02 ,  G01J3/027 ,  G01J3/0272 ,  G01J3/0291 ,  G01J3/51 ,  G01J3/513 ,  G01J3/524 ,  G01N21/274 ,  G01J2001/0257 ,  G01J2001/1636 ,  G01J2003/2866 ,  G01J3/465

Abstract: A spectrophotometer apparatus (200) is adapted to provide spectral reflectance measurements of object samples. The apparatus (200) comprises a source light (254) and a reflection optics assembly (264, 268). Signals representative of reflected light are analyzed and data provided to an operator representative of the spectral response characteristics of the object sample (252). The apparatus (200) further comprises a side sensor (276) having a fixed spectral response characteristic for compensating the reflectance measurements in accordance with the light intensity emanating from the lamp. For purposes of calibration, a series of time-sequenced measurements are made of a reference sample. Utilizing these measurements, the apparatus (200) provides computations of compensation coefficients for each spectral segment. The compensation coefficients are utilized, with the side sensor measurements, to provide normalization of the reflectance measurements for each segment and for each measurement within the timed sequence. For each segment, a scale factor is then determined. The scale factors, compensation coefficients and side sensor measurements are employed to compensate actual reflectance measurements, with further compensation provided by a determination of temperature coefficients.

Abstract translation: 分光光度计装置（200）适于提供对象样品的光谱反射率测量。 装置（200）包括源光（254）和反射光学组件（264,268）。 分析代表反射光的信号，并将数据提供给代表对象样品（252）的光谱响应特性的算子。 装置（200）还包括具有固定频谱响应特性的侧传感器（276），用于根据从灯发出的光强来补偿反射率测量。 为了进行校准，对参考样品进行了一系列时间序列测量。 利用这些测量，装置（200）提供每个光谱段的补偿系数的计算。 利用侧传感器测量，利用补偿系数来提供每个段的反射率测量的归一化以及定时序列内的每个测量的归一化。 对于每个段，然后确定比例因子。 采用比例因子，补偿系数和侧面传感器测量来补偿实际反射率测量，并通过确定温度系数提供进一步的补偿。

公开(公告)号：US5050991A

公开(公告)日：1991-09-24

申请号：US415740

申请日：1989-09-29

Applicant: Jeanne A. Welch

Inventor： Jeanne A. Welch

IPC: G01J1/16 ,  G01J1/44 ,  G01J3/18 ,  G01J3/36 ,  G01J3/42 ,  G01N21/25

CPC classification number: G01J3/42 ,  G01N21/255 ,  G01J2001/1636 ,  G01J2001/442 ,  G01J3/1838 ,  G01J3/36 ,  G01N2201/06166 ,  G01N2201/064

Abstract: An apparatus is disclosed for measuring the spectra of a high optical density sample having substantially known optical properties. In a preferred embodiment, the apparatus comprises: a laser for producing a light beam; a Raman cell responsive to the light beam for generating a first light containing a plurality of preselected wavelength components; an optical system for directing the first light through the sample; a dispersion device for spatially separating the first light passed through the sample into its plurality of preselected wavelength components; a plurality of light detectors positioned to respectively receive the spatially-separated preselected wavelength components and to convert the photons in each of the spatially-separated preselected components into a plurality of associated photocurrents having amplitudes respectively representative of the numbers of photons in the spatially-separated preselected wavelength components; and a photon counter for respectively converting the plurality of associated photocurrents into a plurality of photon counts corresponding to the transmittance of the sample at the respective preselected wavelength components of the first light passing through the sample. In a modification of the invention, the apparatus further includes an energy meter adapted to receive a portion of the light beam for generating an energy signal representative of the total energy in the light beam, and processing means responsive to the plurality of photon counts and to the energy signal for determining the output transmittance of the sample at the preselected wavelength components of the first light passing through the sample.

Abstract translation: 公开了一种用于测量具有基本上已知光学特性的高光密度样品的光谱的装置。 在优选实施例中，该装置包括：用于产生光束的激光器; 响应于所述光束的拉曼单元，用于产生包含多个预选波长分量的第一光; 用于将第一光引导通过样品的光学系统; 用于将通过所述样品的所述第一光线空间分离成其多个预选波长分量的分散装置; 多个光检测器被定位成分别接收空间分离的预选波长分量并将每个空间分离的预选分量中的光子转换成多个相关联的光电流，其具有分别代表空间分离的光子数量的幅度 预选波长分量; 以及光子计数器，用于将多个相关联的光电流分别转换成对应于通过样品的第一光的各个预选波长分量的样品的透射率的多个光子计数。 在本发明的修改中，该装置还包括适于接收光束的一部分以产生表示光束中的总能量的能量信号的能量计，以及响应于多个光子计数的处理装置，以及 用于确定通过样品的第一光的预选波长分量处的样品的输出透射率的能量信号。

公开(公告)号：US4925299A

公开(公告)日：1990-05-15

申请号：US229599

申请日：1988-08-08

Applicant: Artur Meisberger ,  Hans-Jurgen Neumann

Inventor： Artur Meisberger ,  Hans-Jurgen Neumann

IPC: G01N21/27 ,  G01J1/16 ,  G01J1/44 ,  G01N21/25 ,  G01N21/31

CPC classification number: G01N21/3151 ,  G01J1/16 ,  G01J2001/1636 ,  G01N2021/3181 ,  G01N21/256

Abstract: A photoelectric arrangement for the determination of a substance spectrally differently absorbing light in a specimen (1) comprising two alternately switched on light sources (2,3) of different wavelengths matched to the absorption maximum or minimum of the substance, two photoelectric receivers (5,6) arranged in such a manner with respect to the specimen that the one receiver (measuring receiver 5) receives light which traverses the specimen and the other receiver (reference receiver 6) receives light of the light sources directly and an electronic control and evaluation circuit following the photoelectric receivers and controlling the light sources for the determination of the different absorption typical for the substance at the two wavelengths, wherein the control and evaluation circuit comprises a light circuit (7,8,10,11a,11b) following the reference receiver (6) for determining light amounts transmitted by the light sources and defining the switchover instant for the light sources on reaching a predetermined amount of light.

Abstract translation: 一种用于确定样品（1）中光线不同地吸收光的物质的光电装置，包括与所述物质的吸收最大值或最小值匹配的不同波长的两个交替接通的光源（2,3），两个光电接收器（5） ，6）相对于样本以一个接收器（测量接收器5）接收穿过样本的光并且另一个接收器（参考接收机6）直接接收光源的光并且进行电子控制和评估 跟随光电接收器并且控制光源以确定在两个波长处的物质的典型的不同吸收，其中控制和评估电路包括遵循参考的光电路（7,8,10,11a，11b） 接收器（6），用于确定光源传输的光量并定义光源的切换时刻 达到预定量的光。

公开(公告)号：US4775794A

公开(公告)日：1988-10-04

申请号：US115314

申请日：1987-11-02

Applicant: Henry Behmann

Inventor： Henry Behmann

IPC: G01J1/16 ,  G01J1/44 ,  G01N21/31 ,  G01N21/33 ,  G01N33/18 ,  G01J1/42

CPC classification number: G01N33/1826 ,  G01N21/33 ,  G01J2001/1636 ,  G01J2001/4433 ,  G01N2021/3155 ,  G01N2021/3166 ,  G01N2201/0696 ,  G01N2201/0806

Abstract: The invention provides a new method and apparatus for measuring the concentration of ultra-violet light absorbing organic materials liquids, particularly in pure or ultra-pure water, the speed and convenience being such that it is possible to take successive readings with periods as short as ten seconds. The apparatus can be mounted directly in or as a by-pass to a process stream, giving the capability of constant monitoring with virtually instant microprocessor-controlled response to measurements outside a pre-set range. The water to be measured passes upwards in a cylindrical opaque-walled sample cell at the upper end of which is mounted an intense light source, preferably a Xenon flash tube, and at the lower end of which is mounted two transmission photodetectors, which have in front of them respective narrow-band optical transmission filters in the ultra-violet and visible regions. The light source sits on the upper end of a quartz rod which extends into the cell at or below the water inlet and is coaxial with the cell longitudinal axis, the rod serving to direct the light toward the transmission photodetectors. The output from the "visible" photodetector is used to correct the output from the "ultraviolet" photodetector for transmission losses caused by particulates, element fouling and bubbles in the stream. Two reference photodetectors employing two similar transmission filters are disposed close to the flash tube outlet window and their signals are used to correct for variation in the flash tube output.

Abstract translation: 本发明提供了一种用于测量紫外光吸收有机材料液体的浓度的新方法和装置，特别是在纯净或超纯水中，其速度和方便性使得可以连续读数， 十秒钟。 该设备可以直接安装在旁路旁边或作为旁路安装到过程流中，从而能够以预定范围外的测量实际上对微处理器控制的响应进行持续监控。 要测量的水在圆柱形不透明壁样品池中向上通过，其上端安装有强光源，优选氙闪光管，并且其下端安装有两个透射光电检测器，其具有 在它们的前面分别在紫外和可见区域的窄带光传输滤波器。 光源位于石英棒的上端，该石英棒在水入口处或其下方延伸到电池中，并且与电池纵向轴线同轴，该杆用于将光引向透射光电检测器。 来自“可见”光电探测器的输出用于校正“紫外”光电检测器的输出，用于由流中的微粒，元素结垢和气泡引起的传输损失。 使用两个类似的透射滤光器的两个参考光电检测器设置在闪光管出口窗口附近，并且它们的信号用于校正闪光管输出的变化。