公开(公告)号：US20170172868A1

公开(公告)日：2017-06-22

申请号：US14971448

申请日：2015-12-16

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： Viktor Dubovoy ,  Michael Stranick ,  Peter R. Hilliard, JR. ,  Laurence Du-Thumm ,  Long Pan

IPC: A61K8/24 ,  A61K8/88 ,  A61Q15/00

CPC classification number: A61K8/24 ,  A61K8/8158 ,  A61K8/88 ,  A61K2800/30 ,  A61K2800/5426 ,  A61K2800/596 ,  A61Q15/00

Abstract: Described herein, are compositions comprising a soluble quaternary ammonium polymer/polyphosphate complex made by combining ingredients comprising a quaternary ammonium polymer and polyphosphates having 2 or more phosphate units. Methods of making and using these compositions are also described.

公开(公告)号：US12194124B2

公开(公告)日：2025-01-14

申请号：US17658288

申请日：2022-04-07

Applicant: Colgate-Palmolive Company

Inventor： Aixing Fan ,  Min Li ,  Thomas Boyd ,  Shyamala Pillai ,  Katie Truong ,  Laurence Du-Thumm

IPC: A61K8/34 ,  A61K8/20 ,  A61K8/27 ,  A61K8/37 ,  A61K8/41 ,  A61K8/42 ,  A61K8/49 ,  A61K8/86 ,  A61Q15/00 ,  A61Q17/00

Abstract: Compositions, such as personal care compositions, and methods for selectively inhibiting the growth of a detrimental bacteria and promoting the growth of a beneficial bacteria are disclosed. The composition may include a base and one or more fatty alcohols. The one or more fatty alcohols may be present in an amount effective to selectively inhibit the growth of at least one detrimental Gram-positive bacteria and promote the growth of at least one beneficial Gram-positive bacteria on skin. The detrimental Gram-positive bacteria may include Corynebacterium, and the beneficial Gram-positive bacteria may include Staphylococcus.

公开(公告)号：US12133908B2

公开(公告)日：2024-11-05

申请号：US16877821

申请日：2020-05-19

Applicant: Colgate-Palmolive Company

Inventor： Zeenat Nabi ,  Shujiang Cheng ,  Halyna Siomyk ,  Laurence Du-Thumm

IPC: A61K31/198 ,  A61K8/02 ,  A61K8/04 ,  A61K8/44 ,  A61K8/46 ,  A61K31/185 ,  A61Q5/02 ,  A61Q5/12 ,  A61Q15/00 ,  A61Q17/00 ,  A61Q19/00 ,  A61Q19/10

Abstract: Described herein, are personal care compositions comprising taurine in combination with arginine and glycine, and methods for using the compositions to effect reduction of skin irritation and or inflammation, and/or improving barrier repair of the skin.

公开(公告)号：US20210322295A1

公开(公告)日：2021-10-21

申请号：US17304578

申请日：2021-06-23

Applicant: Colgate-Palmolive Company

Inventor： Eugene Hardy ,  Shujiang Cheng ,  Zeenat Nabi ,  Jeffrey Mastrull ,  Evangelia Arvanitidou ,  Laurence Du-Thumm

IPC: A61K8/81 ,  A61K8/42 ,  A61K8/44 ,  A61K8/46 ,  A61Q19/10

Abstract: Described herein, are personal care compositions comprising a surfactant system; an amino acid, e.g. taurine; and a deposition aid comprising a PVM/MA copolymer having a M.W. of from about 30,000 to about 1,000,000, or a vinylimidazolium vinyl pyrrolidone copolymer. Methods of making and using these compositions are also described.

公开(公告)号：US11116708B2

公开(公告)日：2021-09-14

申请号：US16758434

申请日：2017-12-19

Applicant: Colgate-Palmolive Company

Inventor： Shujiang Cheng ,  Zeenat Nabi ,  Laurence Du-Thumm ,  Qiang Wu ,  Jane Ong ,  Halyna Siomyk ,  Harsh Mahendra Trivedi ,  James Masters ,  Chi-Yuan Cheng ,  Donghui Wu

IPC: A61K8/27 ,  A61K8/49 ,  A61K8/60 ,  A61Q15/00 ,  A61Q19/08 ,  A61Q19/02 ,  A61Q11/00

Abstract: Personal care compositions including a naringin:zinc complex and methods for preparing and using the same are provided. The personal care compositions may include a carrier and a naringin:zinc complex having a 2:1 naringin to zinc molar ratio.

公开(公告)号：US11026873B2

公开(公告)日：2021-06-08

申请号：US16066896

申请日：2015-12-31

Applicant: Colgate-Palmolive Company

Inventor： Zeenat Nabi ,  Shujiang Cheng ,  Halyna Siomyk ,  Laurence Du-Thumm

IPC: A61K31/198 ,  A61K8/44 ,  A61Q5/02 ,  A61Q5/12 ,  A61Q15/00 ,  A61Q17/00 ,  A61Q19/00 ,  A61Q19/10 ,  A61K8/46 ,  A61K8/02 ,  A61K8/04 ,  A61K31/185

Abstract: Described herein, are personal care compositions comprising taurine in combination with arginine and glycine, and methods for using the compositions to effect reduction of skin irritation and or inflammation, and/or improving barrier repair of the skin.

公开(公告)号：US09889077B2

公开(公告)日：2018-02-13

申请号：US14527829

申请日：2014-10-30

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： Lyndsay Schaeffer-Korbylo ,  Andre Michelle Morgan ,  Davide Miksa ,  Laurence Du-Thumm ,  Michael Prencipe ,  Evangelia Arvanitidou ,  Gregory Szewczyk

IPC: A61Q11/00 ,  A61K8/97 ,  A61K8/27 ,  A61K8/34 ,  A01N49/00 ,  A61K8/35 ,  A61K8/33 ,  A61K8/49 ,  A61K8/365 ,  A61K8/19 ,  A61K8/21

CPC classification number: A61K8/34 ,  A01N49/00 ,  A61K8/19 ,  A61K8/21 ,  A61K8/33 ,  A61K8/342 ,  A61K8/347 ,  A61K8/35 ,  A61K8/365 ,  A61K8/4926 ,  A61K8/97 ,  A61K2800/92 ,  A61Q11/00 ,  A01N31/08 ,  A01N31/16 ,  A01N43/40 ,  A01N59/16 ,  A01N65/00 ,  A01N2300/00 ,  A01N65/08

Abstract: Disclosed are oral care compositions and the use of such oral care compositions for treating conditions caused by biofilm formation. Also disclosed are methods for inhibiting biofilm formation and/or degrading biofilm. The oral care composition includes a sesquiterpenoid and an antimicrobial agent, in which the sesquiterpenoid and the antimicrobial agent are present in an amount effective to inhibit and/or degrade a biofilm in the oral cavity.

公开(公告)号：US11298306B2

公开(公告)日：2022-04-12

申请号：US16771852

申请日：2017-12-12

Applicant: Colgate-Palmolive Company

Inventor： Qiang Wu ,  Laurence Du-Thumm ,  Joan Gambogi ,  Zeenat Nabi ,  Cristina Bielli ,  Juliana Nwosisi ,  Shujiang Cheng ,  Halyna Siomyk

IPC: A61K8/46 ,  A61K8/92 ,  A61Q15/00

Abstract: An antiperspirant and/or deodorant composition including from 0.01 weight % to 0.15 weight % flaxseed oil and from 0.5 weight % to 5.0 weight % taurine.

公开(公告)号：US10760109B2

公开(公告)日：2020-09-01

申请号：US15316537

申请日：2015-06-08

Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN ,  COLGATE-PALMOLIVE COMPANY

Inventor： Alexander Rickard ,  William Giannobile ,  Michelle Swetky ,  Nielson T. Baxter ,  Steven E. Miller ,  Laurence Du-Thumm ,  Hans Stettler

IPC: C12Q1/04 ,  G16H50/30 ,  C12Q1/18 ,  G01N33/569 ,  C12Q1/66 ,  G06F19/00

Abstract: The present disclosure relates to methods for characterizing and diagnosing dental diseases. In particular, the present disclosure relates to methods for characterizing and diagnosing dental disease (e.g., gingivitis and periodontal disease) based on levels of AI-2 in oral fluids and plaque.

公开(公告)号：US20160304886A1

公开(公告)日：2016-10-20

申请号：US15134007

申请日：2016-04-20

Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN ,  COLGATE-PALMOLIVE COMPANY

Inventor： Alexander Rickard ,  Adam Underwood ,  Laurence Du-Thumm

IPC: C12N15/74 ,  G01N33/84 ,  G01N33/68

Abstract: The present disclosure relates to compositions and methods for destabilizing biofilms, altering biofilm 3D structure, and dispersing biofilms, in order to enhance biofilm cell removal and/or sensitivity to other agents (e.g., environmental or co-applied treatments). In particular, the present disclosure relates to the use of L-arginine in the removal and/or sensitization (e.g., to antimicrobials) of microorganisms in medical, industrial, domestic, or environmental applications, as well as treatment of bacterial infections (e.g., in biofilms).

Abstract translation: 本公开涉及用于使生物膜不稳定，改变生物膜3D结构和分散生物膜的组合物和方法，以增强生物膜细胞去除和/或对其他试剂的敏感性（例如环境或共同施用的处理）。 特别地，本公开内容涉及L-精氨酸在医疗，工业，家庭或环境应用中的微生物的去除和/或致敏（例如，抗微生物剂）中的应用以及细菌感染的治疗（例如， 在生物膜中）。