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公开(公告)号：US10350151B2
公开(公告)日：2019-07-16
申请号：US15539275
申请日：2014-12-26
Applicant: Colgate-Palmolive Company
Inventor： Baohua Qiao , Long Pan , Gregory Szewczyk , Ravi Subramanyam , Shiri Nawrocki , Viktor Dubovoy
Abstract: A soluble zinc polyphosphate complex made by combining ingredients which include an organic zinc salt and a plurality of long chain polyphosphates having 6 or more phosphate polymer units, the organic zinc salt and long chain polyphosphates being mixed in amounts that provide a phosphorus to zinc mole ratio of 15:1 to about 55:1. Further provided is a method of making this soluble zinc polyphosphate.
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公开(公告)号：US10188112B2
公开(公告)日：2019-01-29
申请号：US14650952
申请日：2013-11-20
Applicant: Colgate-Palmolive Company
Inventor： Eugene Hardy , Long Pan , Shiri Nawrocki , Evangelia Arvanitidou , Laurence D. Du-Thumm
IPC: A61K8/58 , A61Q19/10 , A61Q15/00 , A61Q17/04 , A01N55/02 , A01N59/16 , A61K8/27 , A61K8/44 , A61K8/20
Abstract: Provided is a personal cleansing composition for application to the skin which comprises a zinc X halide present in an amount to provide at least 0.36 weight % of the composition of zinc, and a surfactant, wherein X is an amino acid or trimethylglycine. Methods of making and using the compositions are also provided. The zinc X halide is can be used to deliver zinc salts to reduce or prevent sunburn, kill bacteria, or reduce perspiration.
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公开(公告)号：US10118832B2
公开(公告)日：2018-11-06
申请号：US15272357
申请日：2016-09-21
Applicant: Colgate-Palmolive Company
Inventor： Iraklis Pappas , John Vaughn , Long Pan
Abstract: A composition comprising an aluminum chlorohydrate salt, the aluminum chlorohydrate salt having at least 50 mole % Al30 polyhydroxyoxoaluminum cation of all polyhydroxyoxoaluminum cations detectable by quantitative 27Al NMR within the aluminum chlorohydrate salt, and a buffer. The composition can optionally include zirconium. Also disclosed are a method of making an aluminum salt using an increased molar concentration of a starting aluminum salt with a buffer, a method of reducing perspiration with the aluminum chlorohydrate salt, and a method of treating water with the aluminum chlorohydrate salt.
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公开(公告)号：US09980890B2
公开(公告)日：2018-05-29
申请号：US14653324
申请日：2012-12-19
Applicant: Colgate-Palmolive Company
Inventor： Long Pan , Shaotang Yuan , Shira Pilch , James G. Masters , Zhiqiang Liu
Abstract: Disclosed herein are mouthwashes comprising a complex of a zinc ion source acid. Methods of making and using the compositions are also provided.
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公开(公告)号：US09943473B2
公开(公告)日：2018-04-17
申请号：US14653292
申请日：2012-12-19
Applicant: Colgate-Palmolive Company
Inventor： Long Pan , Jairajh Mattai , Shamim Ansari , Jianhong Qiu , James G. Masters , Ying Yang
CPC classification number: A61K8/58 , A61K8/27 , A61K8/44 , A61Q15/00 , A61Q17/005
Abstract: The invention provides a personal care composition for application to the skin which comprises a personal care composition for application to the skin or hair comprising a zinc X halide and a cosmetically acceptable base, wherein X is an amino acid or trimethylglycine. Methods of making and using the compositions are also provided. The zinc X halide is can be used to deliver zinc salts to block perspiration and provide antibacterial effects.
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Patent Agency Ranking
公开(公告)号：US20170340539A1
公开(公告)日：2017-11-30
申请号：US15674557
申请日：2017-08-11
Applicant: Colgate-Palmolive Company
Inventor： Long Pan , Shaotang Yuan , Shira Pilch , James Masters , Zhiqiang Liu , Vyoma Patel
CPC classification number: A61K8/44 , A61K8/042 , A61K8/20 , A61K8/21 , A61K8/27 , A61K8/442 , A61K8/731 , A61K2800/58 , A61K2800/92 , A61Q11/00
Abstract: Disclosed herein are dentifrices comprising a zinc amino acid halide, which provide a precipitate of zinc oxide upon use with dilution with water and/or saliva. Methods of making and using the dentifrices are also provided.
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公开(公告)号：US20170128330A1
公开(公告)日：2017-05-11
申请号：US15224681
申请日：2016-08-01
Applicant: Colgate-Palmolive Company
Inventor： John Vaughn , Iraklis Pappas , Long Pan
CPC classification number: A61K8/26 , A61K8/19 , A61K8/20 , A61K8/28 , A61K8/42 , A61K8/44 , A61K2800/58 , A61Q15/00 , C01F7/002 , C01F7/56 , C01P2002/86 , C01P2002/87
Abstract: An antiperspirant active composition comprising an aluminum salt, the aluminum salt (i) having an aluminum to chloride molar ratio of 0.3:1 to 3:1; and (ii) having a species of polyhydroxyoxoaluminum cation detectable at 76 ppm by 27Al NMR that is present in a relative abundance on a 27Al NMR spectrograph that is greater than any other polyhydroxyoxoaluminum cation detectable by 27Al NMR. Also, disclosed are methods of making the antiperspirant active.
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公开(公告)号：US09585825B2
公开(公告)日：2017-03-07
申请号：US14154216
申请日：2014-01-14
Applicant: Colgate-Palmolive Company
Inventor： Iraklis Pappas , Michael C. Fitzgerald , Long Pan
CPC classification number: A61K8/416 , A61K8/26 , A61K8/42 , A61K8/44 , A61K2800/31 , A61K2800/58 , A61Q15/00
Abstract: A method of producing an anhydrous antiperspirant composition comprising (a) providing a mixture of at least one antiperspirant active including a metal salt, and an anhydrous carrier for the at least one antiperspirant active in which the at least one antiperspirant active is dissolved, the carrier comprising a eutectic mixture of at least one basic compound selected from a basic amide and a basic amine and at least one member chosen from a cation and zwitterion; and (b) heating the mixture to form a stabilized eutectic system of the at least one antiperspirant active and the anhydrous carrier, and wherein the at least one antiperspirant active, the at least one basic compound and the at least one member chosen from a cation and zwitterion form a ternary eutectic system.
Abstract translation: 一种制备无水止汗组合物的方法，其包含（a）提供至少一种止汗剂活性物质（包括金属盐）的混合物和至少一种其中所述至少一种止汗活性剂溶解的止汗活性剂的无水载体，所述载体 包括至少一种选自碱性酰胺和碱性胺的碱性化合物和选自阳离子和两性离子的至少一种的共晶混合物; 和（b）加热所述混合物以形成所述至少一种止汗活性剂和所述无水载体的稳定的共晶体系，并且其中所述至少一种止汗活性剂，所述至少一种碱性化合物和至少一种选自阳离子 并且两性离子形成三元共晶体系。
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19.发明申请TWO COMPONENT COMPOSITIONS CONTAINING TETRABASIC ZINC-AMINO ACID HALIDE COMPLEXES AND CYSTEINE 有权含有四羧酸锌盐酸盐复合物和CYSTEINE的两种组分公开(公告)号：US20160030319A1
公开(公告)日：2016-02-04
申请号：US14653901
申请日：2013-11-07
Applicant: Colgate-Palmolive Company
Inventor： Zhiqiang Liu , Long Pan , Joseph Convery , Shaotang Yuan , Harsh M. Trivedi
CPC classification number: A61K8/447 , A61K8/27 , A61K8/345 , A61K8/44 , A61K2800/58 , A61K2800/5922 , A61K2800/882 , A61Q11/00 , A61Q15/00 , A61Q17/005 , A61Q19/00 , A61Q19/10
Abstract: Provided are compositions, e.g., oral and personal care products, comprising (i) a tetrabasic zinc-amino acid or trialkyl glycine-halide complex, and (ii) cysteine in free or in orally or cosmetically acceptable salt form, together with methods of making and using the same.
Abstract translation: 提供了组合物，例如口服和个人护理产品，其包含（i）四碱基锌 - 氨基酸或三烷基甘氨酸 - 卤化物配合物，和（ii）游离或口服或化妆品可接受的盐形式的半胱氨酸，以及制备方法 并使用相同的。
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公开(公告)号：US20150328112A1
公开(公告)日：2015-11-19
申请号：US14653885
申请日：2012-12-19
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： Guofeng Xu , Zhiqiang Liu , Long Pan , LaTonya Kilpatrick-Liverman , Ying Yang , Michael A. Stranick , Zhigang Hao
CPC classification number: A61K8/27 , A61K8/20 , A61K8/21 , A61K8/44 , A61K2800/58 , A61K2800/92 , A61Q11/00
Abstract: Described herein are oral care compositions comprising a mixture of zinc oxide and trimethylglycine, in free or orally acceptable salt form. Methods of making and using the compositions are also provided.
Abstract translation: 本文描述了包含游离或口服可接受的盐形式的氧化锌和三甲基甘氨酸的混合物的口腔护理组合物。 还提供了制备和使用组合物的方法。
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