公开(公告)号：US12285264B2

公开(公告)日：2025-04-29

申请号：US17333199

申请日：2021-05-28

Applicant: Covidien LP

Inventor： Eric J. Panken ,  Philip E. Tracton ,  Eric M. Christensen ,  Richard J. O'Brien ,  David A. Anderson ,  Avram Scheiner ,  Paul G. Krause ,  Jonathon E. Giftakis ,  John Wainwright ,  Andrew J. Ries ,  Randal C. Schulhauser ,  Ekaterina M. Ippolito

IPC: A61B5/00 ,  A61B5/0205 ,  A61B5/021 ,  A61B5/024 ,  A61B5/28 ,  A61B5/291 ,  A61B5/304 ,  A61B5/318 ,  A61B5/369

Abstract: In some examples, a device includes at least three electrodes a first pair of electrodes and a second pair of electrodes. The device also includes circuitry configured to generate a first cardiac signal based on a first differential signal received across the first pair, generate a first brain signal based on the first differential signal received across the first pair, generate a second cardiac signal based on a second differential signal received across the second pair, and generate a second brain signal based on the second differential signal received across the second pair. The circuitry is also configured to output a composite cardiac signal based on the first cardiac signal and the second cardiac signal and to output a composite brain signal based on the first brain signal and the second brain signal.

公开(公告)号：US12016582B2

公开(公告)日：2024-06-25

申请号：US18053217

申请日：2022-11-07

Applicant: Covidien LP

Inventor： Hoai Nguyen ,  Gaurav Girdhar ,  Andyanhdzung Huynh ,  Ujwal Jalgaonkar ,  Eric Mintz ,  Ashok Nageswaran ,  John Wainwright

IPC: A61B17/221 ,  A61B17/22 ,  A61L29/02 ,  A61M25/00

CPC classification number: A61B17/221 ,  A61L29/02 ,  A61B2017/22094 ,  A61B2017/2212 ,  A61M2025/0042

Abstract: Retrieval of material from vessel lumens can be improved by use of a distal element comprising an expandable mesh. a treatment device includes an elongated member having a proximal portion and a distal portion configured to be positioned within a blood vessel at a treatment site at or near a thrombus. A distal element comprising an expandable mesh is coupled to the distal portion of the elongated member via a connection assembly. In an expanded state, at least a portion of the mesh is configured to be in apposition with the blood vessel wall at the treatment site to anchor or stabilize the elongated member with respect to the blood vessel. The distal element can be electrically coupled to an extracorporeal current generator.

公开(公告)号：US20240189121A1

公开(公告)日：2024-06-13

申请号：US18581322

申请日：2024-02-19

Applicant: Covidien LP

Inventor： Xiaodong Ma ,  Min-Shyan Sheu ,  Lincoln Eramo ,  John Wainwright ,  Junwei Li

IPC: A61F2/82 ,  A61F2/06 ,  A61F2/90 ,  A61L31/02 ,  A61L31/10 ,  A61L31/14 ,  A61L31/16 ,  A61L33/00 ,  A61L33/06 ,  B05D1/18 ,  B05D3/14

CPC classification number: A61F2/82 ,  A61F2/06 ,  A61F2/90 ,  A61L31/022 ,  A61L31/10 ,  A61L31/146 ,  A61L31/16 ,  A61L33/0088 ,  A61L33/064 ,  A61F2240/001 ,  A61L2300/42 ,  A61L2400/18 ,  A61L2420/02 ,  B05D1/18 ,  B05D3/142

Abstract: Methods for forming an expandable tubular body having a plurality of braided filaments including a first filament including platinum or platinum alloy and a second filament including cobalt-chromium alloy. The methods include applying a first phosphorylcholine material directly on the platinum or platinum alloy of the first filament and applying a silane material on the second filament followed by a second phosphorylcholine material on the silane material on the second filament. The first and second phosphorylcholine materials each define a thickness of less than 100 nanometers.

公开(公告)号：US11903850B2

公开(公告)日：2024-02-20

申请号：US17818585

申请日：2022-08-09

Applicant: Covidien LP

Inventor： Xiaodong Ma ,  Min-Shyan Sheu ,  Lincoln Eramo ,  John Wainwright ,  Junwei Li

IPC: A61L33/00 ,  A61F2/82 ,  A61L31/02 ,  A61L31/16 ,  A61F2/90 ,  A61L31/10 ,  A61F2/06 ,  A61L31/14 ,  A61L33/06 ,  B05D1/18 ,  B05D3/14

CPC classification number: A61F2/82 ,  A61F2/06 ,  A61F2/90 ,  A61L31/022 ,  A61L31/10 ,  A61L31/146 ,  A61L31/16 ,  A61L33/0088 ,  A61L33/064 ,  A61F2240/001 ,  A61L2300/42 ,  A61L2400/18 ,  A61L2420/02 ,  B05D1/18 ,  B05D3/142

Abstract: Methods for forming an expandable tubular body having a plurality of braided filaments including a first filament including platinum or platinum alloy and a second filament including cobalt-chromium alloy. The methods include applying a first phosphorylcholine material directly on the platinum or platinum alloy of the first filament and applying a silane material on the second filament followed by a second phosphorylcholine material on the silane material on the second filament. The first and second phosphorylcholine materials each define a thickness of less than 100 nanometers.

公开(公告)号：US20230277187A1

公开(公告)日：2023-09-07

申请号：US17653269

申请日：2022-03-02

Applicant: Covidien LP

Inventor： Mark Philip Ashby ,  Ashok Nageswaran ,  Eric Mintz ,  Gaurav Girdhar ,  Ujwal Ramesh Jalgaonkar ,  John Wainwright

IPC: A61B17/12

CPC classification number: A61B17/12118 ,  A61B17/12168 ,  A61B2017/1205

Abstract: Expandable devices for occluding bifurcation aneurysms are disclosed herein. Several of the embodiments are directed towards an expandable device comprising a mesh configured to be deployed at a treatment site including blood vessel bifurcation of a human patient so that the mesh extends across a neck of an aneurysm and prevents or limits blood flow through the mesh and into the aneurysm. The mesh can comprise one or more circumferentially discontinuous portions so that, when the device is deployed at the treatment site, the device does not substantially impede flow from a parent blood vessel to two or more branching blood vessels. Systems and methods for delivering an expandable device of the present technology are also disclosed herein.

公开(公告)号：US11523838B2

公开(公告)日：2022-12-13

申请号：US16439642

申请日：2019-06-12

Applicant: Covidien LP

Inventor： Hoai Nguyen ,  Gaurav Girdhar ,  Andyanhdzung Huynh ,  Ujwal Jalgaonkar ,  Eric Mintz ,  Ashok Nageswaran ,  John Wainwright

IPC: A61B17/221 ,  A61B17/22 ,  A61M25/00 ,  A61L29/02

Abstract: Retrieval of material from vessel lumens can be improved by use of a distal element comprising an expandable mesh, a treatment device includes an elongated member having a proximal portion and a distal portion configured to be positioned within a blood vessel at a treatment site at or near a thrombus. A distal element comprising an expandable mesh is coupled to the distal portion of the elongated member via a connection assembly. In an expanded state, at least a portion of the mesh is configured to be in apposition with the blood vessel wall at the treatment site to anchor or stabilize the elongated member with respect to the blood vessel. The distal element can be electrically coupled to an extracorporeal current generator.

公开(公告)号：US20210251578A1

公开(公告)日：2021-08-19

申请号：US17006444

申请日：2020-08-28

Applicant: Covidien LP

Inventor： Randal C. Schulhauser ,  John Wainwright ,  Eric J. Panken ,  Jadin C. Jackson ,  Alejo Chavez Gaxiola ,  Aaron Gilletti ,  Eduardo N. Warman ,  Paul G. Krause ,  Eric M. Christensen ,  Patrick W. Kinzie ,  Julia Slopsema

IPC: A61B5/00 ,  A61B5/0478 ,  A61B5/04 ,  A61B5/0205 ,  A61B5/042 ,  A61B5/11

Abstract: A system for detecting strokes includes a sensor device configured to obtain physiological data from a patient, for example brain activity data. The sensor device can include electrodes configured to be disposed at the back of the patient's neck or base of the skull. The electrodes can detect electrical signals corresponding to brain activity in the P3, Pz, and/or P4 brain regions or other brain regions. A computing device communicatively coupled to the sensor device is configured to receive the physiological data and analyze it to indicate whether the patient has suffered a stroke.

公开(公告)号：US20210000624A1

公开(公告)日：2021-01-07

申请号：US16948385

申请日：2020-09-16

Applicant: Covidien LP

Inventor： Anh Cam ,  Michael Losordo ,  Jianlu Ma ,  Luong Nguyen ,  Sanjay Shrivastava ,  John Wainwright ,  Xiaoling Zhao

IPC: A61F2/90 ,  A61B17/12 ,  A61F2/95

Abstract: Vascular remodeling devices can include a proximal section, an intermediate section, and a distal section. During deployment, the proximal section can expand from a compressed delivery state to an expanded state and anchor the device in an afferent vessel of a bifurcation. The distal section expands from the compressed delivery state to an expanded state that may be substantially planar, approximately semi-spherical, umbrella shaped, or reverse umbrella shaped. The distal section is positioned in a bifurcation junction across the neck of an aneurysm or within an aneurysm. The intermediate section allows perfusion to efferent vessels. Before or after the device is in position, embolic material may be used to treat the aneurysm. The distal section can act as a scaffolding to prevent herniation of the embolic material. The device can be used for clot retrieval with integral distal embolic protection.

公开(公告)号：US20200323664A1

公开(公告)日：2020-10-15

申请号：US16913871

申请日：2020-06-26

Applicant: Covidien LP

Inventor： John Wainwright ,  Todd Mendelson ,  Kurt Haggstrom ,  Masoud Molaei ,  Victoria Schuman ,  Min-Shyan Sheu

IPC: A61F2/90 ,  A61F2/07 ,  B05D1/18 ,  B05D3/02 ,  B05D3/04

Abstract: Medical devices that include a tubular member with a plurality of braided filaments, each filament crossing another of the filaments at a respective crossing point forming sidewall and a plurality of pores in the sidewall that are sized to inhibit flow of blood through the sidewall into an aneurysm to a degree sufficient to lead to thrombosis and healing of the aneurysm when the tubular member is positioned in a blood vessel and adjacent to the aneurysm, the pores have an average pore size that is less than or equal to about 500 microns when the tubular member is in an expanded state, the filaments possessing antithrombogenic surfaces to increase antithrombogenicity of the medical device with pores substantially free of webs formed by antithrombogenic material, such that fewer than 5% of the crossing points have webs formed by antithrombogenic material thereby permitting the pores to be substantially free of webs.

公开(公告)号：US20200061099A1

公开(公告)日：2020-02-27

申请号：US16669978

申请日：2019-10-31

Applicant: Covidien LP

Inventor： Junwei Li ,  Gaurav Girdhar ,  John Wainwright ,  Yves Bayon ,  Ariana Pagani

IPC: A61K31/722 ,  A61B17/12 ,  A61M5/145 ,  A61M25/10 ,  A61L31/14 ,  A61L31/18 ,  A61L31/04

Abstract: A method for treating an aneurysm in accordance with a particular embodiment of the present technology includes intravascularly delivering a mixture including a biopolymer (e.g., chitosan) and a chemical crosslinking agent (e.g., genipin) to an aneurysm. The method further includes mixing the biopolymer and the chemical crosslinking agent to initiate chemical crosslinking of the biopolymer. The mixture is delivered to the aneurysm via a lumen and an exit port of a catheter while the chemical crosslinking is ongoing. The mixture exits the catheter as a single cohesive strand that at least partially agglomerates to form a mass occupying at least 75% of a total internal volume of the aneurysm. During delivery of the mixture, the method includes expanding a tubular flow diverter to reinforce a neck of the aneurysm.