-
公开(公告)号：US20190350965A1
公开(公告)日：2019-11-21
申请号：US16527740
申请日：2019-07-31
Applicant: Covidien LP
Inventor： Rachit Ohri , Phillip D. Blaskovich , Min-Shyan Sheu , Petra Brockfeld
IPC: A61K31/717 , A61K33/20 , A61L26/00 , A61K31/714 , A61K49/04 , A61K31/295 , A61K33/24 , A61K31/445
Abstract: A method of treatment includes agitating a thixotropic oxidized cellulose solution; administering the agitated thixotropic oxidized cellulose solution to a target tissue site; and allowing the agitated thixotropic oxidized cellulose solution to gel at the target tissue site.
-
公开(公告)号：US10040871B2
公开(公告)日：2018-08-07
申请号：US13927311
申请日：2013-06-26
Applicant: Confluent Surgical, Inc. , Covidien LP
Inventor： Valentino Tramontano , Phillip Blaskovich , Rachit Ohri , Joshua Kennedy , Sajida Farooqi
Abstract: A process for dissolving modified cellulose includes contacting modified cellulose with a solvent in a mixture to form swelled modified cellulose and then contacting the mixture with a salt to dissolve the swelled modified cellulose. The dissolved modified cellulose is used to form at least one of a predictably degrading coating, film, or a fiber.
-
13.发明授权Dissolution of oxidized cellulose and particle preparation by cross-linking with multivalent cations 有权通过与多价阳离子交联，氧化纤维素和颗粒制剂的溶解公开(公告)号：US09499636B2
公开(公告)日：2016-11-22
申请号：US13927316
申请日：2013-06-26
Applicant: Confluent Surgical, Inc. , Covidien LP
Inventor： Phillip Blaskovich , Valentino Tramontano , Rachit Ohri , Daniel S. Costa , Joshua Kennedy , Sajida Farooqi
CPC classification number: C08B1/003 , C08B15/00 , C08B15/005 , C08B15/02 , C08J3/075 , C08J3/096 , C08J3/14 , C08J2301/04 , C08L1/04
Abstract: A process for dissolving modified cellulose includes contacting modified cellulose solution with at least one multivalent cation to form a plurality of modified cellulose particles.
Abstract translation: 溶解改性纤维素的方法包括将改性纤维素溶液与至少一种多价阳离子接触以形成多个改性纤维素颗粒。
-
公开(公告)号：US20160089335A1
公开(公告)日：2016-03-31
申请号：US14848385
申请日：2015-09-09
Applicant: Covidien LP
Inventor： Rachit Ohri , Gary R. Strichartz , Phillip Blaskovich
IPC: A61K9/16 , A61K31/445
CPC classification number: A61K9/1647 , A61K9/0024 , A61K31/445
Abstract: A microsphere is disclosed. The microsphere includes at least one biodegradable polymer and at least one local anesthetic, wherein about 75% of the at least one local anesthetic is released by about 72 hours and from about 80% to about 90% of the at least one local anesthetic is released by about 120 hours, thereby relieving chronic pain for at least 28 days.
Abstract translation: 公开了一种微球。 微球包括至少一种可生物降解的聚合物和至少一种局部麻醉剂，其中约75％的至少一种局部麻醉剂释放约72小时，并且至少一种局部麻醉剂的约80％至约90％释放 约120小时，从而缓解至少28天的慢性疼痛。
-
公开(公告)号：US08932618B2
公开(公告)日：2015-01-13
申请号：US13939720
申请日：2013-07-11
Applicant: Covidien LP
Inventor： Phillip D. Blaskovich , Rachit Ohri , Steven L. Bennett
CPC classification number: A61K9/0004 , A61K9/0024
Abstract: The present disclosure relates to a drug delivery device including a biodegradable housing and a hydrogel within the biodegradable housing. The housing, the hydrogel, or both, may include a bioactive agent. Also disclosed is a method of drug delivery including the steps of forming the biodegradable housing, in embodiments a hydrogel, suspending a bioactive agent in the hydrogel, and introducing a second hydrogel and/or precursors of a second hydrogel into the biodegradable housing.
Abstract translation: 本公开涉及一种药物递送装置，其包括可生物降解的壳体内的可生物降解的壳体和水凝胶。 壳体，水凝胶或两者可以包括生物活性剂。 还公开了药物递送的方法，包括形成可生物降解的壳体的步骤，在实施方案中为水凝胶，将生物活性剂悬浮在水凝胶中，以及将第二水凝胶和/或第二水凝胶的前体引入可生物降解的壳体中。
-
Patent Agency Ranking
公开(公告)号：US10982012B2
公开(公告)日：2021-04-20
申请号：US15353997
申请日：2016-11-17
Applicant: Covidien LP
Inventor： Valentino J. Tramontano , Joshua Kennedy , Sajida Farooqi , Phillip D. Blaskovich , Rachit Ohri , Daniel S. Costa
IPC: C08B16/00 , C08K3/16 , C08K5/20 , C08K5/3415 , C08J3/09 , C08B15/02 , C08J3/12 , C08L1/04 , A61K9/16
Abstract: A process for dissolving modified cellulose is disclosed. The process includes contacting modified cellulose with a solvent in a mixture to form swelled modified cellulose and then contacting the mixture with a salt to dissolve the swelled modified cellulose.
-
公开(公告)号：US20190117575A1
公开(公告)日：2019-04-25
申请号：US16225169
申请日：2018-12-19
Applicant: Covidien LP
Inventor： Phillip Blaskovich , Rachit Ohri , Lan Pham
IPC: A61K9/16 , A61L27/20 , A61L15/28 , B01J13/12 , A61K31/445 , A61K31/714 , A61K33/24
CPC classification number: A61K9/1682 , A61K9/1652 , A61K9/1694 , A61K31/445 , A61K31/714 , A61K33/24 , A61L15/28 , A61L27/20 , B01J13/12 , B01J13/125
Abstract: A process for forming microspheres is disclosed. The process includes contacting a solvent with a modified cellulose to form a solution; contacting the modified cellulose solution with at least one bioactive agent to form a discontinuous phase liquid; contacting the discontinuous phase liquid with a continuous phase liquid to form an emulsion; and contacting the emulsion with a third phase liquid to extract the solvent from the emulsion, thereby forming a plurality of modified cellulose microspheres.
-
公开(公告)号：US20180305468A1
公开(公告)日：2018-10-25
申请号：US16022772
申请日：2018-06-29
Applicant: Covidien LP
Inventor： Valentino Tramontano , Phillip Blaskovich , Rachit Ohri , Joshua Kennedy , Sajida Farooqi
Abstract: A process for dissolving modified cellulose includes contacting modified cellulose with a solvent in a mixture to form swelled modified cellulose and then contacting the mixture with a salt to dissolve the swelled modified cellulose. The dissolved modified cellulose is used to form at least one of a predictably degrading coating, film, or a fiber.
-
19.发明申请Dissolution of Oxidized Cellulose and Particle Preparation by Solvent and Non-Solvent Precipitation 审中-公开氧化纤维素的溶解和溶剂和非溶剂沉淀的颗粒制备公开(公告)号：US20160369013A1
公开(公告)日：2016-12-22
申请号：US15255263
申请日：2016-09-02
Applicant: Covidien LP
Inventor： Valentino Tramontano , Phillip Blaskovich , Rachit Ohri , Daniel S. Costa , Joshua Kennedy , Sajida Farooqi
CPC classification number: C08B1/003 , C08B15/00 , C08B15/005 , C08B15/02 , C08J3/096 , C08J3/14 , C08J2301/04
Abstract: A process for dissolving modified cellulose includes contacting modified cellulose solution with at least one non-solvent to form a plurality of modified cellulose particles.
Abstract translation: 用于溶解改性纤维素的方法包括使改性纤维素溶液与至少一种非溶剂接触以形成多个改性的纤维素颗粒。
-
20.发明授权Dissolution of oxidized cellulose and particle preparation by dispersion and neutralization 有权通过分散和中和溶解氧化纤维素和颗粒制剂公开(公告)号：US09447197B2
公开(公告)日：2016-09-20
申请号：US13927315
申请日：2013-06-26
Applicant: Confluent Surgical, Inc. , Covidien LP
Inventor： Valentino Tramontano , Phillip Blaskovich , Rachit Ohri , Daniel S. Costa , Joshua Kennedy , Sajida Farooqi
Abstract: A process for dissolving modified cellulose includes contacting modified cellulose solution with at least one neutralizing agent to form a plurality of modified cellulose particles.
Abstract translation: 溶解改性纤维素的方法包括使改性纤维素溶液与至少一种中和剂接触以形成多个改性纤维素颗粒。
-
-
-
-
-
-
-
-
-
Search Results
48
records
(took 0.022 seconds)
