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    INDAZOLINONE COMPOSITIONS USEFUL AS KINASE INHIBITORS
    15.
    发明申请
    INDAZOLINONE COMPOSITIONS USEFUL AS KINASE INHIBITORS 有权
    恩佐酮组合物可用作激酶抑制剂

    公开(公告)号：US20090048250A1

    公开(公告)日：2009-02-19

    申请号：US11841233

    申请日：2007-08-20

    申请人： Alex Aronov ,  David J. Lauffer ,  Huan Qiu Li ,  Ronald Charles Tomlinson ,  Pan Li

    发明人： Alex Aronov ,  David J. Lauffer ,  Huan Qiu Li ,  Ronald Charles Tomlinson ,  Pan Li

    IPC分类号： A61K31/5377 ,  C07D231/54 ,  A61K31/4152 ,  C07D471/04 ,  C07D413/04 ,  A61K31/437 ,  C07D403/02 ,  A61K31/53

    CPC分类号： C07D403/14 ,  C07D407/14 ,  C07D409/14 ,  C07D471/04

    摘要： The present invention provides compounds of formula I: These compounds, and pharmaceutically acceptable compositions thereof, are useful generally as kinase inhibitors, particularly as inhibitors of PRAK, GSK3, ERK2, CDK2, MK2, SRC, SYK, and Aurora-2. Accordingly, compounds and compositions of the invention are useful for treating or lessening the severity of a variety of disorders, including, but not limited to, heart disease, diabetes, Alzheimer's disease, immunodeficiency disorders, inflammatory diseases, allergic diseases, autoimmune diseases, destructive bone disorders such as osteoporosis, proliferative disorders, infectious diseases and viral diseases.

    摘要翻译： 本发明提供式I化合物：这些化合物及其药学上可接受的组合物通常用作激酶抑制剂，特别是作为PRAK，GSK3，ERK2，CDK2，MK2，SRC，SYK和Aurora-2的抑制剂。 因此，本发明的化合物和组合物可用于治疗或减轻各种障碍的严重性，包括但不限于心脏病，糖尿病，阿尔茨海默氏病，免疫缺陷病症，炎性疾病，过敏性疾病，自身免疫疾病，破坏性 骨质疏松症，增殖性疾病，感染性疾病和病毒性疾病等骨骼疾病。

    Method and device for measuring system performance in real time
    18.
    发明授权
    Method and device for measuring system performance in real time 有权

    公开(公告)号：US09606886B2

    公开(公告)日：2017-03-28

    申请号：US13822812

    申请日：2011-07-06

    申请人： Pan Li

    发明人： Pan Li

    IPC分类号： H04W24/10 ,  H04L12/26 ,  G06F11/30 ,  G06F11/34 ,  H04W24/08

    CPC分类号： G06F11/3065 ,  G06F11/3409 ,  G06F11/3466 ,  G06F11/3476 ,  G06F11/3495 ,  H04L43/062 ,  H04L43/0829 ,  H04L43/106 ,  H04W24/08 ,  H04W24/10

    摘要： Disclosed are method and device for measuring system performance in real time. The method includes: the foreground receives a real-time measurement task comprising a measurement period parameter constructed by the background according to the concerned service data, with the quantity of the service data being lower than a preset value; the foreground extracts the current data corresponding to the real-time measurement task from a performance measurement cache area according to the measurement period parameter; the foreground acquires the real-time measurement data corresponding to the real-time measurement task according to the current data; and the foreground reports the real-time measurement data to the background. In the present invention, the background sends the concerned service data to the foreground by way of a real-time measurement task, and the foreground merely reports few service data.