公开(公告)号：US20180306824A1

公开(公告)日：2018-10-25

申请号：US15493433

申请日：2017-04-21

申请人： David R. Hall ,  Dan Allen ,  Daniel Hendricks ,  Andrew Nguyen ,  Conrad Rosenbrock ,  Travis Niederhauser ,  Joe Fox ,  Terrece Pearman ,  Steven J.M. Butala

发明人： David R. Hall ,  Dan Allen ,  Daniel Hendricks ,  Andrew Nguyen ,  Conrad Rosenbrock ,  Travis Niederhauser ,  Joe Fox ,  Terrece Pearman ,  Steven J.M. Butala

IPC分类号： G01N33/94 ,  A61B5/15 ,  A61B10/00 ,  G01N21/359

CPC分类号： G01N21/359 ,  A61B5/145 ,  A61B10/0038 ,  A61B10/0051 ,  A61B10/007 ,  A61B2010/0009 ,  A61B2010/0061 ,  A61B2010/0077 ,  A61B2010/0087 ,  G01N30/02 ,  G01N33/15 ,  G01N2458/15

摘要： We disclose a method of tagging nutritional or drug compositions using chemical entities which are known to be safely consumed and which are detectable using known techniques, including near IR spectroscopy. The chemical entities used as tags may be detected in easily obtainable biological samples, including urine and feces. The biological sample may be deposited into a medical toilet which may analyze the biological sample using an analytical device associated with the medical toilet. The tag may be identified and quantified to then identify and quantify the nutritional or drug composition the subject consumed along with the tag. This system may be used to track the source of a food or drug, confirm compliance to a prescribed diet or drug treatment, confirm drug consumption in clinical trials, identify the source of contaminated food, and identify the food substances used to produce food products.

公开(公告)号：US20180265916A1

公开(公告)日：2018-09-20

申请号：US15460575

申请日：2017-03-16

申请人： David R. Hall ,  Dan Allen ,  Conrad Rosenbrock ,  Andrew Nguyen ,  Ben Swenson ,  Daniel Hendricks

发明人： David R. Hall ,  Dan Allen ,  Conrad Rosenbrock ,  Andrew Nguyen ,  Ben Swenson ,  Daniel Hendricks

IPC分类号： C12Q1/68

CPC分类号： C12Q1/68 ,  C12Q2563/143 ,  C12Q2563/155 ,  C12Q2563/185

摘要： We disclose a drug tracking system and method of use which may be used to screen a user's bodily waste and to collect information about the drugs the user has consumed. The system includes mixing or adhering a drug tag with a drug compound. The drug tag includes at least one nucleic acid or nucleic acid analog, the unique nucleotide sequence of which correlates to information about the drug. The unique sequence may correlate with a drug molecule, a drug class, a manufacturer, and/or a distributer. Each of these categories of information may be incorporated into the nucleotide sequence of a separate nucleic acid or nucleic acid analog molecules or combined in a single molecule. The sequence of the drug tag may be entered into a database which stores the drug information associated with each discrete nucleotide sequence.

公开(公告)号：US20180334669A1

公开(公告)日：2018-11-22

申请号：US15597633

申请日：2017-05-17

申请人： David R. Hall ,  Steven J.M. Butala ,  Dan Allen ,  Andrew Nguyen ,  Conrad Rosenbrock ,  Ben Swenson ,  Daniel Hendricks ,  Joe Fox

发明人： David R. Hall ,  Steven J.M. Butala ,  Dan Allen ,  Andrew Nguyen ,  Conrad Rosenbrock ,  Ben Swenson ,  Daniel Hendricks ,  Joe Fox

IPC分类号： C12N15/10

CPC分类号： C12N15/1065

摘要： We disclose a method of tagging a variety of pharmaceutical or nutritional products in which well-studied chemicals may be added to the products in unique ratios. The identities of the chemicals and their relative ratios comprise unique taggants. The taggants may identify which of multiple distinct categories the product falls within. The method includes the step of systematically varying the relative concentrations of the chemicals resulting in multiple ratios of the chemicals. The plurality of ratios of a defined set of chemicals may be collected to form a library of taggants associated with specified items or categories. As the number of chemicals added per product increases, the library supports more categories and the system is less likely to produce a false positive. The method may result in a series of taggants for each item which is single fault tolerant or double fault tolerant.

公开(公告)号：US09863967B1

公开(公告)日：2018-01-09

申请号：US15670191

申请日：2017-08-07

申请人： David R. Hall ,  Conrad Rosenbrock ,  Ben Swenson ,  Daniel Hendricks ,  Joe Fox ,  Terrece Pearman

发明人： David R. Hall ,  Conrad Rosenbrock ,  Ben Swenson ,  Daniel Hendricks ,  Joe Fox ,  Terrece Pearman

IPC分类号： G01N21/64 ,  E03D11/11 ,  E03D11/13 ,  G01N33/493 ,  G01N33/94 ,  A61B10/00

CPC分类号： G01N33/94 ,  A61B10/007 ,  E03D11/025 ,  E03D11/11 ,  E03D11/13 ,  G01N21/6428 ,  G01N21/645 ,  G01N33/493 ,  G01N2021/6417 ,  G01N2201/061

摘要： The present disclosure describes a method of detecting a drug marker in a urine sample. The drug markers are fluorophores each of which emits a unique fluorescence spectrum. Accordingly, the method does not detect the drug but rather, the drug marker. The drug marker may include quantum dots which may be functionalized by connecting the quantum dot to a biomolecule. The biomolecule may be cleavable by a peptidase, a protease, or a nuclease to release the drug. Alternatively, the composition may include a liposome carrier. A user who has consumed the drug composition provides a urine sample. The fluorescence spectrometer screens the urine for drug markers based on their unique fluorescent spectra.

公开(公告)号：US10060112B1

公开(公告)日：2018-08-28

申请号：US15611348

申请日：2017-06-01

申请人： David R. Hall ,  Steven J. M. Butala ,  Dan Allen ,  Andrew Nguyen ,  Conrad Rosenbrock ,  Ben Swenson ,  Daniel Hendricks ,  Travis Niederhauser ,  John Christensen ,  Joshua Larsen ,  Joe Fox

发明人： David R. Hall ,  Steven J. M. Butala ,  Dan Allen ,  Andrew Nguyen ,  Conrad Rosenbrock ,  Ben Swenson ,  Daniel Hendricks ,  Travis Niederhauser ,  John Christensen ,  Joshua Larsen ,  Joe Fox

IPC分类号： E03D9/10 ,  E03D5/10 ,  E03D5/014 ,  G01N33/58 ,  G01N33/487 ,  B01F1/00 ,  G01N33/00

CPC分类号： G01N33/48785 ,  B01F5/0615 ,  B01F5/0688 ,  B01F7/00908 ,  B01F7/00916 ,  B01F11/0258 ,  B01F13/0818 ,  B01F15/0237 ,  G01N33/48714 ,  G01N2033/0003

摘要： We disclose a toilet system which analyzes solid waste to detect tags which were associated with pharmaceutical or nutritional products and excreted in the solid waste of a user. The toilet system may include a receptacle for receiving solid waste, a liquid dispenser for providing a liquid to assist in dispersing the solid waste, a solid waste dispersing system which may mix the solid waste with the liquid thereby homogenizing the solid waste, and an electromagnetic signature detector which may analyze the tags in the solid waste. The electromagnetic signature detector may include a selective binding surface which may bind tags present in the solid waste and which may be connected to a transducer which senses the presence of bound tags.

公开(公告)号：US10012660B2

公开(公告)日：2018-07-03

申请号：US15834441

申请日：2017-12-07

申请人： David R. Hall ,  Conrad Rosenbrock ,  Ben Swenson ,  Daniel Hendricks ,  Joe Fox ,  Terrece Pearman

发明人： David R. Hall ,  Conrad Rosenbrock ,  Ben Swenson ,  Daniel Hendricks ,  Joe Fox ,  Terrece Pearman

IPC分类号： G01N33/58 ,  G01N21/64 ,  A61B10/00 ,  E03D11/13 ,  E03D11/11 ,  G01N33/94 ,  G01N33/493

CPC分类号： G01N33/94 ,  A61B10/007 ,  E03D11/025 ,  E03D11/11 ,  E03D11/13 ,  G01N21/6428 ,  G01N21/645 ,  G01N33/493 ,  G01N2021/6417 ,  G01N2201/061

摘要： The present disclosure describes a toilet apparatus for detecting a drug marker in a urine sample. The drug markers are fluorophores each of which emits a unique fluorescence spectrum. Accordingly, the toilet does not detect the drug but rather, the drug marker. The user consumes a drug composition which includes a drug and a fluorescent drug marker. The user urinates normally into the toilet and fluorescence spectrometer within the toilet analyzes the urine for drug markers based on their unique fluorescent spectra. Computer software associated with the toilet identifies, and in some embodiments, quantifies the fluorescent spectra by comparing the detected spectra to known spectra of fluorescent markers associated with the drug.

公开(公告)号：US20180149666A1

公开(公告)日：2018-05-31

申请号：US15834441

申请日：2017-12-07

申请人： David R. Hall ,  Conrad Rosenbrock ,  Ben Swenson ,  Daniel Hendricks ,  Joe Fox ,  Terrece Pearman

发明人： David R. Hall ,  Conrad Rosenbrock ,  Ben Swenson ,  Daniel Hendricks ,  Joe Fox ,  Terrece Pearman

IPC分类号： G01N33/94 ,  G01N21/64 ,  E03D11/11 ,  A61B10/00 ,  E03D11/13 ,  G01N33/493

CPC分类号： G01N33/94 ,  A61B10/007 ,  E03D11/025 ,  E03D11/11 ,  E03D11/13 ,  G01N21/6428 ,  G01N21/645 ,  G01N33/493 ,  G01N2021/6417 ,  G01N2201/061

摘要： The present disclosure describes a toilet apparatus for detecting a drug marker in a urine sample. The drug markers are fluorophores each of which emits a unique fluorescence spectrum. Accordingly, the toilet does not detect the drug but rather, the drug marker. The user consumes a drug composition which includes a drug and a fluorescent drug marker. The user urinates normally into the toilet and fluorescence spectrometer within the toilet analyzes the urine for drug markers based on their unique fluorescent spectra. Computer software associated with the toilet identifies, and in some embodiments, quantifies the fluorescent spectra by comparing the detected spectra to known spectra of fluorescent markers associated with the drug.

公开(公告)号：US09766257B1

公开(公告)日：2017-09-19

申请号：US15497638

申请日：2017-04-26

申请人： David R. Hall ,  Conrad Rosenbrock ,  Ben Swenson ,  Daniel Hendricks ,  Joe Fox ,  Terrece Pearman

发明人： David R. Hall ,  Conrad Rosenbrock ,  Ben Swenson ,  Daniel Hendricks ,  Joe Fox ,  Terrece Pearman

IPC分类号： G01N21/64 ,  E03D11/11 ,  E03D11/13 ,  G01N33/493 ,  G01N33/94 ,  A61B10/00

CPC分类号： G01N33/94 ,  A61B10/007 ,  E03D11/025 ,  E03D11/11 ,  E03D11/13 ,  G01N21/6428 ,  G01N21/645 ,  G01N33/493 ,  G01N2021/6417 ,  G01N2201/061

摘要： The present disclosure describes a method of detecting a drug marker in urine a urine sample using a toilet. The drug markers are fluorophores each of which emits a unique fluorescence spectra. Accordingly, the method does not detect the drug but rather, the drug marker. The drug marker may include quantum dots which may be functionalized by connecting the quantum dot to a biomolecule. The biomolecule may be cleavable by a peptidase, a protease, or a nuclease to release the drug. Alternatively, the composition may include a liposome carrier. A user who has consumed the drug composition urinates into the toilet and a urine sample is captured. The toilet includes a mechanism for fluid handling which diverts urine into a fluorescence spectrometer. The fluorescence spectrometer screens the urine for drug markers based on their unique fluorescent spectra.

公开(公告)号：US09671343B1

公开(公告)日：2017-06-06

申请号：US15361872

申请日：2016-11-28

申请人： David R. Hall ,  Conrad Rosenbrock ,  Ben Swenson ,  Dan Hendricks ,  Terrece Pearman

发明人： David R. Hall ,  Conrad Rosenbrock ,  Ben Swenson ,  Dan Hendricks ,  Terrece Pearman

IPC分类号： G01N21/64 ,  E03D11/11 ,  E03D11/13 ,  G01N33/493

CPC分类号： G01N21/6428 ,  E03D11/025 ,  E03D11/11 ,  E03D11/13 ,  G01N21/645 ,  G01N33/493 ,  G01N2021/6439

摘要： The present disclosure describes a method of detecting a drug marker in urine a urine sample using a toilet. The drug markers are fluorophores each of which emits a unique fluorescence spectra. Accordingly, the method does not detect the drug but rather, the drug marker. A user who has consumed the drug with its unique drug marker then urinates into the toilet and a urine sample is captured. The toilet includes a mechanism for fluid handling which diverts urine into a fluorescence spectrometer. The fluorescence spectrometer screens the urine for drug markers based on their unique fluorescent spectra. The toilet may include a controller which quantifies the drug marker. The fluorescent spectrometer may detect multiple drug markers in a single urine sample. This method may be used to confirm drug compliance, test for illicit drugs, identify amounts of drugs consumed, and other uses described herein.

公开(公告)号：US20180165421A1

公开(公告)日：2018-06-14

申请号：US15377048

申请日：2016-12-13

申请人： David R. Hall ,  Dan Allen ,  Ben Swenson ,  Conrad Rosenbrock

发明人： David R. Hall ,  Dan Allen ,  Ben Swenson ,  Conrad Rosenbrock

IPC分类号： G06F19/00

CPC分类号： G06F19/3462 ,  G06F19/3418 ,  G07F17/0092 ,  G16H20/13 ,  G16H40/20 ,  G16H40/67

摘要： We disclose a telemedicine device for tracking, dispensing, and retrieving medical supplies as well as methods of its use. The device includes a medical supply dispensing and retrieving station which includes a medical supply dispenser and medical supply receptacle. Both the medical supply dispenser and medical supply receptacle may include multiple compartments which house medical supplies. The device may include a communication port for receiving prescription information. The device includes a personal identification indicator which verifies the identity of the user and links the identity to the user's prescription information. The device may include medical devices. The medical devices may conduct measurements to confirm efficacy of a medical supply or screen for side effects. The device may confirm proper usage of a medical supply by weighing an unused portion of the medical supply and comparing it to the weight expected for the amount that should be remaining.