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    Transcatheter heart valve for replacing natural mitral valve
    11.
    发明授权
    Transcatheter heart valve for replacing natural mitral valve 有权

    公开(公告)号：US10470876B2

    公开(公告)日：2019-11-12

    申请号：US15345857

    申请日：2016-11-08

    Applicant: Edwards Lifesciences Corporation

    Inventor： Nikolay Gurovich ,  Mohammad Jafari ,  Liron Tayeb ,  Ilan Tamir ,  Ziv Yohanan ,  Noam Nir ,  David Maimon ,  Boaz Manash

    IPC: A61F2/24

    Abstract: Embodiments of prosthetic valves for implantation within a native mitral valve are provided. A prosthetic valve may comprise a radially compressible main body and a one-way valve portion. The prosthetic valve may further comprise one or more ventricular anchors coupled to the main body and disposed outside of the main body. The ventricular anchors may be configured such that a reduced profile of the prosthetic valve is possible. A space may be provided between an outer surface of the main body and the ventricular anchors for receiving native mitral valve leaflets. The prosthetic valve may include an atrial sealing member adapted for placement above the annulus of the mitral valve. Methods and devices for receiving the native mitral valve leaflets between the ventricular anchors and the main body are described.

    EXPANDABLE SHEATH
    12.
    发明申请
    EXPANDABLE SHEATH 审中-公开

    公开(公告)号：US20190307589A1

    公开(公告)日：2019-10-10

    申请号：US16378417

    申请日：2019-04-08

    Applicant: Edwards Lifesciences Corporation

    Inventor： Eran Goldberg ,  Noa Axelrod ,  Yair A. Neumann ,  Boaz Manash ,  David Maimon ,  Eyal Leiba ,  Ralph Schneider ,  Liron Tayeb

    IPC: A61F2/966 ,  A61M29/00

    Abstract: An expandable sheath is disclosed herein, which has a first polymeric layer and a braided layer positioned radially outward of the first polymeric layer. The braided layer includes a plurality of filaments braided together. The expandable sheaths further include a resilient elastic layer positioned radially outward of the braided layer. The elastic layer is configured to apply radial force to the braided layer and the first polymeric layer. The expandable sheath further includes a second polymeric layer positioned radially outward of the elastic layer and bonded to the first polymeric layer such that the braided layer and the elastic layer are encapsulated between the first and second polymeric layers. Methods of making and using the devices disclosed herein are also disclosed, as are crimping devices that may be used in methods of making the devices disclosed herein.

    ACTIVE HOLDER FOR ANNULOPLASTY RING DELIVERY
    13.
    发明申请
    ACTIVE HOLDER FOR ANNULOPLASTY RING DELIVERY 审中-公开

    公开(公告)号：US20190029829A1

    公开(公告)日：2019-01-31

    申请号：US16148864

    申请日：2018-10-01

    Applicant: Edwards Lifesciences Corporation

    Inventor： Yaron Keidar ,  Wesley V. Adzich ,  Dan Rottenberg ,  Boaz Manash ,  Alon Nahshon

    IPC: A61F2/24

    Abstract: An active annuloplasty ring holder having a template that can be folded or pivoted to the side allowing the template to align longitudinally with the handle and enter the patient's chest through a small incision. The holder may include a mechanism to remotely detach sutures fastening the ring to the holder, thereby detaching the ring while avoiding the risk associated with introducing a scalpel into the operating field. A detachment mechanism may include a movable pin actuated by a pull wire that releases a plurality of holding sutures, or a hot wire, knives, or pull wire that severs the sutures. The holder may have a built-in light source for better visualization of the ring inside the heart. The holder may also have an optical means of visualizing the inside of the heart from the proximal end of the handle.

    Unidirectional valvular implant
    14.
    发明授权
    Unidirectional valvular implant 有权

    公开(公告)号：US12245756B2

    公开(公告)日：2025-03-11

    申请号：US17334479

    申请日：2021-05-28

    Applicant: Edwards Lifesciences Corporation

    Inventor： Boaz Manash ,  Eitan Atias ,  Liron Tayeb ,  Amir Blumenfeld ,  David Maimon ,  Eyal Leiba

    IPC: A61B17/00 ,  A61F2/24

    Abstract: Valvular implants and blood vessel closure devices herein are configured to be positioned in the heart and to block regurgitant blood flow from the heart into blood vessels supplying blood to the heart. The valvular implants can have a cover, a membrane, a valve, a resilient frame, and/or other features. Some valvular implants can have anchors to be positioned in the blood vessels, such as in pulmonary veins, and can anchor the implant to the heart wall. Various embodiments of covers and/or membranes act as valves contracting and expanding, to alternately permit and block blood flow. The valvular implants can cover one or more blood vessels, such as one, two, three, or four pulmonary veins, and can also be configured and implanted to block an appendage to the heart, such as the left atrial appendage.

    Mechanically expandable heart valve
    16.
    发明授权
    Mechanically expandable heart valve 有权

    公开(公告)号：US11951003B2

    公开(公告)日：2024-04-09

    申请号：US17339316

    申请日：2021-06-04

    Applicant: Edwards Lifesciences Corporation

    Inventor： Boaz Manash

    IPC: A61F2/24 ,  A61F2/95

    CPC classification number: A61F2/2418 ,  A61F2/2415 ,  A61F2/243 ,  A61F2/2436 ,  A61F2/9517 ,  A61F2220/0033 ,  A61F2220/0075 ,  A61F2220/0091

    Abstract: In one embodiment, a prosthetic valve can comprise a radially expandable and compressible frame, which can include a plurality of struts which are pivotally joined together without requiring individual rivets. In some embodiments, the struts are interwoven, and can be joined using integral hinges formed in the struts, such as by performing alternate cuts on the struts, bending the struts to form stopper tabs adjacent to joints and/or drilling holes in the struts to facilitate interconnecting struts at joints, or otherwise forming integral hinges and corresponding holes at junction points between the struts. In another embodiment, the frame comprises a plurality of inner struts and outer struts which are connected by a plurality of chains of interconnected rivets, avoiding the need to provide individual rivets at each junction between struts. In still another embodiment, separate hinges or flanged rivets are provided to interconnect the struts.

    Active holder for annuloplasty ring delivery
    20.
    发明授权
    Active holder for annuloplasty ring delivery 有权

    公开(公告)号：US11576784B2

    公开(公告)日：2023-02-14

    申请号：US17100381

    申请日：2020-11-20

    Applicant: Edwards Lifesciences Corporation

    Inventor： Yaron Keidar ,  W. Vaso Adzich ,  Dan Rottenberg ,  Boaz Manash ,  Alon Nahshon

    IPC: A61F2/24

    Abstract: An active annuloplasty ring holder having a template that can be folded or pivoted to the side allowing the template to align longitudinally with the handle and enter the patient's chest through a small incision. The holder may include a mechanism to remotely detach sutures fastening the ring to the holder, thereby detaching the ring while avoiding the risk associated with introducing a scalpel into the operating field. A detachment mechanism may include a movable pin actuated by a pull wire that releases a plurality of holding sutures, or a hot wire, knives, or pull wire that severs the sutures. The holder may have a built-in light source for better visualization of the ring inside the heart. The holder may also have an optical means of visualizing the inside of the heart from the proximal end of the handle.

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